Compile Data Set for Download or QSAR

Found 278 hits Enz. Inhib. hit(s) with all data for entry = 10970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581928 (US11510915, Example 283) Show SMILES Cc1ccc(c(F)c1)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:12:13:16.15:18.20| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0620	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456491 (US10723742, Example 218 | US10723742, Example 221 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31ClF2N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(29(35)28(30)33)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(34)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581933 (US11510915, Example 288) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:22:23:26.25:28.30| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581938 (US11510915, Example 293) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:22:23:26.25:28.30| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456476 (US10723742, Example 202 | US11510915, Example 202) Show SMILES Cc1noc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:34:33:31.30:28| Show InChI InChI=1S/C28H22F2N4O2/c1-14-20-11-24(30)22(12-27(20)36-33-14)19-6-4-16(28(35)34-18-5-7-26(34)25(32)10-18)8-21(19)15-2-3-17(13-31)23(29)9-15/h2-4,6,8-9,11-12,18,25-26H,5,7,10,32H2,1H3/t18-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581930 (US11510915, Example 285) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:20:21:24.23:26.28| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581931 (US11510915, Example 286) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2Cc1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 |TLB:8:7:5.4:1.2| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0930	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456487 (US10723742, Example 214 | US10723742, Example 217 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31F3N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(28(34)29(30)35)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(33)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456492 (US10723742, Example 219 | US11510915, Example 219) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C30H29ClF2N6O2/c1-3-30(41,4-2)16-39-28-25(36-37-39)13-23(27(33)26(28)31)21-8-7-18(29(40)38-10-9-20(35)15-38)11-22(21)17-5-6-19(14-34)24(32)12-17/h5-8,11-13,20,41H,3-4,9-10,15-16,35H2,1-2H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581932 (US11510915, Example 287) Show SMILES CC(C)(O)Cn1ncc2cc(c(F)cc12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:19:20:23.22:25.27| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456471 (US10723742, Example 197 | US11510915, Example 197) Show SMILES CC(C)(O)Cn1ncc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C30H28F3N5O2/c1-29(2,40)15-38-27-20(14-36-38)11-23(25(32)26(27)33)21-7-6-18(28(39)37-9-8-30(3,35)16-37)10-22(21)17-4-5-19(13-34)24(31)12-17/h4-7,10-12,14,40H,8-9,15-16,35H2,1-3H3/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456500 (US10723742, Example 228 | US10723742, Example 241 ...) Show SMILES Cc1c(F)c(cc2nnn(CC(C)(C)O)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C31H30F2N6O2/c1-16-28(33)23(13-26-29(16)38(37-36-26)15-31(2,3)41)21-8-6-18(30(40)39-20-7-9-27(39)25(35)12-20)10-22(21)17-4-5-19(14-34)24(32)11-17/h4-6,8,10-11,13,20,25,27,41H,7,9,12,15,35H2,1-3H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456304 (US10723742, Example 123 | US10723742, Example 23 |...) Show SMILES Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:35:34:30.31:28| Show InChI InChI=1S/C30H26F2N4O/c1-35-9-8-18-10-26(28(32)15-29(18)35)24-7-4-19(11-25(24)17-2-3-20(16-33)27(31)12-17)30(37)36-22-5-6-23(36)14-21(34)13-22/h2-4,7-12,15,21-23H,5-6,13-14,34H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456493 (US10723742, Example 220 | US11510915, Example 220) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:42:41:37.38:35| Show InChI InChI=1S/C33H33ClF2N6O2/c1-3-33(44,4-2)17-41-31-28(39-40-41)15-26(30(36)29(31)34)24-10-7-19(11-25(24)18-5-6-20(16-37)27(35)12-18)32(43)42-22-8-9-23(42)14-21(38)13-22/h5-7,10-12,15,21-23,44H,3-4,8-9,13-14,17,38H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456528 (US10723742, Example 257 | US10723742, Example 269 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 |THB:0:1:5.4:7| Show InChI InChI=1S/C31H27ClF2N6O2/c32-27-28(34)22(13-25-29(27)39(38-37-25)15-31(42)8-1-9-31)20-6-4-17(30(41)40-19-5-7-26(40)24(36)12-19)10-21(20)16-2-3-18(14-35)23(33)11-16/h2-4,6,10-11,13,19,24,26,42H,1,5,7-9,12,15,36H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456525 (US10723742, Example 254 | US10723742, Example 268 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(F)c2F)c(c1)-c1ccc(C#N)c(F)c1 |THB:0:1:5.4:7| Show InChI InChI=1S/C31H27F3N6O2/c32-23-11-16(2-3-18(23)14-35)21-10-17(30(41)40-19-5-7-26(40)24(36)12-19)4-6-20(21)22-13-25-29(28(34)27(22)33)39(38-37-25)15-31(42)8-1-9-31/h2-4,6,10-11,13,19,24,26,42H,1,5,7-9,12,15,36H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456529 (US10723742, Example 258 | US11510915, Example 258) Show SMILES N[C@H]1CCN(C1)C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C29H25ClF2N6O2/c30-25-26(32)22(12-24-27(25)38(36-35-24)15-29(40)7-1-8-29)20-5-4-17(28(39)37-9-6-19(34)14-37)10-21(20)16-2-3-18(13-33)23(31)11-16/h2-5,10-12,19,40H,1,6-9,14-15,34H2/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456449 (US10723742, Example 175 | US10723742, Example 185 ...) Show SMILES Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:35:34:32.31:29| Show InChI InChI=1S/C27H21F3N6O/c1-35-26-22(33-34-35)11-19(24(29)25(26)30)17-6-4-14(27(37)36-16-5-7-23(36)21(32)10-16)8-18(17)13-2-3-15(12-31)20(28)9-13/h2-4,6,8-9,11,16,21,23H,5,7,10,32H2,1H3/t16-,21+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456470 (US10723742, Example 196 | US11510915, Example 196) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C32H29F3N4O2/c1-32(2,41)16-38-10-9-18-11-24(28(34)29(35)30(18)38)22-7-5-19(31(40)39-21-6-8-27(39)26(37)14-21)12-23(22)17-3-4-20(15-36)25(33)13-17/h3-5,7,9-13,21,26-27,41H,6,8,14,16,37H2,1-2H3/t21-,26+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456485 (US10723742, Example 211 | US11510915, Example 211) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:40:39:35.36:33| Show InChI InChI=1S/C31H29ClF2N6O2/c1-31(2,42)15-39-29-26(37-38-39)13-24(28(34)27(29)32)22-8-5-17(9-23(22)16-3-4-18(14-35)25(33)10-16)30(41)40-20-6-7-21(40)12-19(36)11-20/h3-5,8-10,13,19-21,42H,6-7,11-12,15,36H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581904 (US11510915, Example 259) Show SMILES NC1CC2CCC(C1)N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 |TLB:9:8:4.5:1.2.7| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456531 (US10723742, Example 260 | US10723742, Example 263 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(c(c1)-c1ccc(C#N)c(F)c1)-c1cc2nnn(CC3(O)CCC3)c2c(C(F)F)c1F |THB:0:1:5.4:7| Show InChI InChI=1S/C32H28F4N6O2/c33-23-11-16(2-3-18(23)14-37)21-10-17(31(43)42-19-5-7-26(42)24(38)12-19)4-6-20(21)22-13-25-29(27(28(22)34)30(35)36)41(40-39-25)15-32(44)8-1-9-32/h2-4,6,10-11,13,19,24,26,30,44H,1,5,7-9,12,15,38H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581939 (US11510915, Example 294) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:20:21:24.23:26.28| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456464 (US10723742, Example 190 | US11510915, Example 190) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C31H30F2N4O2/c1-30(2,39)17-36-10-8-20-12-25(27(33)15-28(20)36)23-7-6-21(29(38)37-11-9-31(3,35)18-37)13-24(23)19-4-5-22(16-34)26(32)14-19/h4-8,10,12-15,39H,9,11,17-18,35H2,1-3H3/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456484 (US10723742, Example 210 | US11510915, Example 210) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C28H25ClF2N6O2/c1-28(2,39)14-37-26-23(34-35-37)11-21(25(31)24(26)29)19-6-5-16(27(38)36-8-7-18(33)13-36)9-20(19)15-3-4-17(12-32)22(30)10-15/h3-6,9-11,18,39H,7-8,13-14,33H2,1-2H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456541 (US10723742, Example 270 | US10723742, Example 276 ...) Show SMILES Cc1c(F)c(cc2nnn(CC3(O)CCC3)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:40:39:37.36:34| Show InChI InChI=1S/C32H30F2N6O2/c1-17-29(34)24(14-27-30(17)39(38-37-27)16-32(42)9-2-10-32)22-7-5-19(31(41)40-21-6-8-28(40)26(36)13-21)11-23(22)18-3-4-20(15-35)25(33)12-18/h3-5,7,11-12,14,21,26,28,42H,2,6,8-10,13,16,36H2,1H3/t21-,26+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581940 (US11510915, Example 295) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:22:23:26.25:28.30| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456517 (US10723742, Example 246 | US10723742, Example 252 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(C(F)F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C31H28F4N6O2/c1-31(2,43)14-40-28-24(38-39-40)12-21(27(33)26(28)29(34)35)19-7-5-16(30(42)41-18-6-8-25(41)23(37)11-18)9-20(19)15-3-4-17(13-36)22(32)10-15/h3-5,7,9-10,12,18,23,25,29,43H,6,8,11,14,37H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581686 (US11510915, Example 23) Show SMILES Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1(N)CCC2 |THB:26:28:34.35.36:30.31| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456472 (US10723742, Example 198 | US11510915, Example 198) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C31H29F3N4O2/c1-30(2,40)16-37-10-8-19-12-24(26(33)27(34)28(19)37)22-7-6-20(29(39)38-11-9-31(3,36)17-38)13-23(22)18-4-5-21(15-35)25(32)14-18/h4-8,10,12-14,40H,9,11,16-17,36H2,1-3H3/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581934 (US11510915, Example 289) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)cc12)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:19:20:23.22:25.27| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456544 (US10723742, Example 273 | US10723742, Example 277 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27BrF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456469 (US10723742, Example 195 | US11510915, Example 195) Show SMILES CC(C)(O)Cn1ncc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C31H28F3N5O2/c1-31(2,41)15-38-29-19(14-37-38)10-23(27(33)28(29)34)21-7-5-17(30(40)39-20-6-8-26(39)25(36)12-20)9-22(21)16-3-4-18(13-35)24(32)11-16/h3-5,7,9-11,14,20,25-26,41H,6,8,12,15,36H2,1-2H3/t20-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456491 (US10723742, Example 218 | US10723742, Example 221 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31ClF2N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(29(35)28(30)33)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(34)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456480 (US10723742, Example 206 | US10723742, Example 225 ...) Show SMILES CCC(O)(CC)Cn1ncc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:40:39:37.36:34| Show InChI InChI=1S/C33H33F2N5O2/c1-3-33(42,4-2)18-39-31-15-28(35)26(12-22(31)17-38-39)24-9-7-20(32(41)40-23-8-10-30(40)29(37)14-23)11-25(24)19-5-6-21(16-36)27(34)13-19/h5-7,9,11-13,15,17,23,29-30,42H,3-4,8,10,14,18,37H2,1-2H3/t23-,29+,30+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456508 (US10723742, Example 237 | US10723742, Example 243 ...) Show SMILES CNC(=O)Cc1cn(C)c2cc(F)c(cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C32H29F2N5O2/c1-37-31(40)11-20-16-38(2)30-14-27(34)25(13-24(20)30)22-7-5-18(32(41)39-21-6-8-29(39)28(36)12-21)9-23(22)17-3-4-19(15-35)26(33)10-17/h3-5,7,9-10,13-14,16,21,28-29H,6,8,11-12,36H2,1-2H3,(H,37,40)/t21-,28+,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456382 (US10723742, Example 103 | US11510915, Example 103) Show SMILES Cc1nc2cc(ccc2n1C)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C27H24FN5O/c1-16-31-25-13-18(6-8-26(25)32(16)2)22-7-5-19(27(34)33-10-9-21(30)15-33)11-23(22)17-3-4-20(14-29)24(28)12-17/h3-8,11-13,21H,9-10,15,30H2,1-2H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456413 (US10723742, Example 134 | US11510915, Example 134) Show SMILES Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C27H22F2N4O/c1-32-8-6-17-10-23(25(29)13-26(17)32)21-5-4-18(27(34)33-9-7-20(31)15-33)11-22(21)16-2-3-19(14-30)24(28)12-16/h2-6,8,10-13,20H,7,9,15,31H2,1H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456487 (US10723742, Example 214 | US10723742, Example 217 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31F3N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(28(34)29(30)35)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(33)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456546 (US10723742, Example 275 | US11510915, Example 275) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:40:39:35.36:33| Show InChI InChI=1S/C31H29BrF2N6O2/c1-31(2,42)15-39-29-26(37-38-39)13-24(28(34)27(29)32)22-8-5-17(9-23(22)16-3-4-18(14-35)25(33)10-16)30(41)40-20-6-7-21(40)12-19(36)11-20/h3-5,8-10,13,19-21,42H,6-7,11-12,15,36H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456465 (US10723742, Example 191 | US11510915, Example 191) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C29H27F3N6O2/c1-28(2,40)14-38-26-23(35-36-38)12-21(24(31)25(26)32)19-7-6-17(27(39)37-9-8-29(3,34)15-37)10-20(19)16-4-5-18(13-33)22(30)11-16/h4-7,10-12,40H,8-9,14-15,34H2,1-3H3/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456451 (US10723742, Example 177 | US10723742, Example 192 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27F3N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(26(32)27(28)33)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(31)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456518 (US10723742, Example 247 | US11510915, Example 247) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(C#N)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:40:39:37.36:34| Show InChI InChI=1S/C31H27F2N7O2/c1-31(2,42)15-39-29-23(14-35)28(33)22(12-26(29)37-38-39)20-7-5-17(30(41)40-19-6-8-27(40)25(36)11-19)9-21(20)16-3-4-18(13-34)24(32)10-16/h3-5,7,9-10,12,19,25,27,42H,6,8,11,15,36H2,1-2H3/t19-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456526 (US10723742, Example 255 | US11510915, Example 255) Show SMILES N[C@H]1CCN(C1)C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(F)c2F)c(c1)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C29H25F3N6O2/c30-23-11-16(2-3-18(23)13-33)21-10-17(28(39)37-9-6-19(34)14-37)4-5-20(21)22-12-24-27(26(32)25(22)31)38(36-35-24)15-29(40)7-1-8-29/h2-5,10-12,19,40H,1,6-9,14-15,34H2/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456542 (US10723742, Example 271 | US11510915, Example 271) Show SMILES Cc1c(F)c(cc2nnn(CC3(O)CCC3)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C30H28F2N6O2/c1-17-27(32)24(13-26-28(17)38(36-35-26)16-30(40)8-2-9-30)22-6-5-19(29(39)37-10-7-21(34)15-37)11-23(22)18-3-4-20(14-33)25(31)12-18/h3-6,11-13,21,40H,2,7-10,15-16,34H2,1H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM581935 (US11510915, Example 290) Show SMILES CC(C)(O)Cc1ccc(c(F)c1)-c1ccc(CN2[C@@H]3CC[C@H]2[C@@H](N)C3)cc1-c1ccc(C#N)c(F)c1 |THB:16:17:20.19:22.24| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456477 (US10723742, Example 203 | US11510915, Example 203) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC2CNCC2C1 Show InChI InChI=1S/C32H29F3N4O2/c1-32(2,41)17-38-8-7-19-9-26(28(34)29(35)30(19)38)24-6-5-20(31(40)39-15-22-13-37-14-23(22)16-39)10-25(24)18-3-4-21(12-36)27(33)11-18/h3-11,22-23,37,41H,13-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456527 (US10723742, Example 256 | US11510915, Example 256) Show SMILES NC1CC2CCC(C1)N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(F)c2F)c(c1)-c1ccc(C#N)c(F)c1 |TLB:0:1:4.5:8| Show InChI InChI=1S/C32H29F3N6O2/c33-26-11-17(2-3-19(26)15-36)24-10-18(31(42)41-21-5-6-22(41)13-20(37)12-21)4-7-23(24)25-14-27-30(29(35)28(25)34)40(39-38-27)16-32(43)8-1-9-32/h2-4,7,10-11,14,20-22,43H,1,5-6,8-9,12-13,16,37H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair

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