Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102217 (3-[5-(4-Fluoro-phenylcarbamoyl)-1-oxy-pyridine-2-s...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102229 (6-Benzenesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicoti...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102225 (CHEMBL39740 | N'-(3-[2,2']Bithiophenyl-5-yl-6,7-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Compound binding was evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human C-X-C chem... | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102216 (6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102219 (CHEMBL61835 | N-(4-Fluoro-phenyl)-6-methanesulfony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102226 (CHEMBL58619 | N-(4-Fluoro-phenyl)-1-oxy-6-phenylme...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102218 (CHEMBL61655 | N-(4-Fluoro-phenyl)-1-oxy-6-(propane...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102230 (6-Cyclopentanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-n...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102221 (6-Chloro-N-(4-fluoro-phenyl)-1-oxy-nicotinamide | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102224 (6-Chloro-N-(4-iodo-phenyl)-1-oxy-nicotinamide | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102228 (CHEMBL60578 | N-Benzhydryl-6-chloro-1-oxy-nicotina...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102227 (6-Chloro-N-cyclohexyl-1-oxy-nicotinamide | CHEMBL6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102220 (CHEMBL293139 | N-(4-tert-Butyl-phenyl)-6-chloro-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102223 (6-Chloro-N-(4-methoxy-phenyl)-1-oxy-nicotinamide |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102214 (6-Chloro-N-(4-fluoro-benzyl)-1-oxy-nicotinamide | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50102215 (6-Chloro-N-(2-hydroxy-phenyl)-1-oxy-nicotinamide |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Celltech R&D Curated by ChEMBL | Assay Description Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2 | Bioorg Med Chem Lett 11: 1951-4 (2001) BindingDB Entry DOI: 10.7270/Q2TX3DN0 | |||||||||||
More data for this Ligand-Target Pair |