Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257612 (CHEMBL493950 | N-benzyl-N-methyl-2,3,4,5-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257620 (7-(4-(2-fluorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257563 (CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257614 (7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257565 (CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257611 (CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257562 (CHEMBL492348 | N-(2-chlorophenyl)-2,3,4,5-tetrahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 156 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257616 (4-(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylsulfon...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257564 (CHEMBL511044 | N-(cyclopropylmethyl)-2,3,4,5-tetra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257610 (CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 382 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257609 (CHEMBL493151 | N-propyl-2,3,4,5-tetrahydro-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 531 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257566 (CHEMBL492950 | N-methyl-N-phenyl-2,3,4,5-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257570 (7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257568 (7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257571 ((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257569 (7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257618 ((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human 5HT2A receptor expressed in mouse Swiss 3T3 cells by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257625 (7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257626 (7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257569 (7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257571 ((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257627 (7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257625 (7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257570 (7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257568 (7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257618 ((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257626 (7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257563 (CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257565 (CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257614 (7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257610 (CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 69 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50257611 (CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257627 (7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 84 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH | |||||||||||
More data for this Ligand-Target Pair |
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