Compile Data Set for Download or QSAR

Found 134 hits Enz. Inhib. hit(s) with all data for entry = 50035262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50120157 (C-[(R)-C-((R)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@@H]([C@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120162 (C-((R)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...) Show SMILES CCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1cccc(F)c1 Show InChI InChI=1S/C21H26ClFN2/c1-2-3-10-19(15-6-5-9-18(23)14-15)25-12-11-20(25)21(24)16-7-4-8-17(22)13-16/h4-9,13-14,19-21H,2-3,10-12,24H2,1H3/t19?,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120151 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-pent...) Show SMILES CCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C21H27ClN2/c1-2-3-12-19(16-8-5-4-6-9-16)24-14-13-20(24)21(23)17-10-7-11-18(22)15-17/h4-11,15,19-21H,2-3,12-14,23H2,1H3/t19?,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120147 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120147 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120140 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...) Show SMILES CCCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C22H29ClN2/c1-2-3-5-13-20(17-9-6-4-7-10-17)25-15-14-21(25)22(24)18-11-8-12-19(23)16-18/h4,6-12,16,20-22H,2-3,5,13-15,24H2,1H3/t20?,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120156 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-7-12-19(16-20)22(25)21-14-15-26(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120137 (C-((R)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3,5-difluo...) Show SMILES CCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C21H25ClF2N2/c1-2-3-7-19(15-11-17(23)13-18(24)12-15)26-9-8-20(26)21(25)14-5-4-6-16(22)10-14/h4-6,10-13,19-21H,2-3,7-9,25H2,1H3/t19?,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120167 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES Cc1ccc(cc1F)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25FN2/c1-17-12-13-20(16-21(17)25)23(26)22-14-15-27(22)24(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-13,16,22-24H,14-15,26H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120166 (C-[(R)-C-{(S)-1-[Bis-(3-fluoro-phenyl)-methyl]-aze...) Show SMILES N[C@@H]([C@@H]1CCN1C(c1cccc(F)c1)c1cccc(F)c1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H21ClF2N2/c24-18-7-1-4-15(12-18)22(27)21-10-11-28(21)23(16-5-2-8-19(25)13-16)17-6-3-9-20(26)14-17/h1-9,12-14,21-23H,10-11,27H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120145 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-buty...) Show SMILES CCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C20H25ClN2/c1-2-7-18(15-8-4-3-5-9-15)23-13-12-19(23)20(22)16-10-6-11-17(21)14-16/h3-6,8-11,14,18-20H,2,7,12-13,22H2,1H3/t18?,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120149 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-p-toly...) Show SMILES Cc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2/c1-18-12-14-19(15-13-18)23(25)22-16-17-26(22)24(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120139 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120155 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N2/c24-19-13-18(14-20(25)15-19)22(26)21-11-12-27(21)23(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,13-15,21-23H,11-12,26H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120167 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES Cc1ccc(cc1F)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25FN2/c1-17-12-13-20(16-21(17)25)23(26)22-14-15-27(22)24(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-13,16,22-24H,14-15,26H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120167 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES Cc1ccc(cc1F)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25FN2/c1-17-12-13-20(16-21(17)25)23(26)22-14-15-27(22)24(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-13,16,22-24H,14-15,26H2,1H3/t22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120161 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-11-17(12-14-20)22(25)21-15-16-26(21)23(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,21-23H,15-16,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120138 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hept...) Show SMILES CCCCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C23H31ClN2/c1-2-3-4-8-14-21(18-10-6-5-7-11-18)26-16-15-22(26)23(25)19-12-9-13-20(24)17-19/h5-7,9-13,17,21-23H,2-4,8,14-16,25H2,1H3/t21?,22-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120150 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(F)c1 Show InChI InChI=1S/C23H23FN2/c24-20-13-7-12-19(16-20)22(25)21-14-15-26(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120165 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-met...) Show SMILES COc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2O/c1-27-21-14-12-18(13-15-21)23(25)22-16-17-26(22)24(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120148 (C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3,5-difluo...) Show SMILES CCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C21H25ClF2N2/c1-2-3-7-19(15-11-17(23)13-18(24)12-15)26-9-8-20(26)21(25)14-5-4-6-16(22)10-14/h4-6,10-13,19-21H,2-3,7-9,25H2,1H3/t19?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	347	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120146 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-buty...) Show SMILES CCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C20H25ClN2/c1-2-7-18(15-8-4-3-5-9-15)23-13-12-19(23)20(22)16-10-6-11-17(21)14-16/h3-6,8-11,14,18-20H,2,7,12-13,22H2,1H3/t18?,19-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	367	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120154 (C-[(R)-C-{(S)-1-[Bis-(3-chloro-phenyl)-methyl]-aze...) Show SMILES N[C@@H]([C@@H]1CCN1C(c1cccc(Cl)c1)c1cccc(Cl)c1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H21Cl3N2/c24-18-7-1-4-15(12-18)22(27)21-10-11-28(21)23(16-5-2-8-19(25)13-16)17-6-3-9-20(26)14-17/h1-9,12-14,21-23H,10-11,27H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120149 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-p-toly...) Show SMILES Cc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2/c1-18-12-14-19(15-13-18)23(25)22-16-17-26(22)24(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	488	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120157 (C-[(R)-C-((R)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@@H]([C@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	516	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120164 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120161 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-11-17(12-14-20)22(25)21-15-16-26(21)23(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,21-23H,15-16,25H2/t21-,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	586	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120161 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-11-17(12-14-20)22(25)21-15-16-26(21)23(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,21-23H,15-16,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	607	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120167 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES Cc1ccc(cc1F)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25FN2/c1-17-12-13-20(16-21(17)25)23(26)22-14-15-27(22)24(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-13,16,22-24H,14-15,26H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	634	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120157 (C-[(R)-C-((R)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@@H]([C@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	641	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120149 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-p-toly...) Show SMILES Cc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2/c1-18-12-14-19(15-13-18)23(25)22-16-17-26(22)24(20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120153 (C-((S)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...) Show SMILES CCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1cccc(F)c1 Show InChI InChI=1S/C21H26ClFN2/c1-2-3-10-19(15-6-5-9-18(23)14-15)25-12-11-20(25)21(24)16-7-4-8-17(22)13-16/h4-9,13-14,19-21H,2-3,10-12,24H2,1H3/t19?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120143 (C-[(R)-C-{(S)-1-[Bis-(4-fluoro-phenyl)-methyl]-aze...) Show SMILES N[C@@H]([C@@H]1CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H21ClF2N2/c24-18-3-1-2-17(14-18)22(27)21-12-13-28(21)23(15-4-8-19(25)9-5-15)16-6-10-20(26)11-7-16/h1-11,14,21-23H,12-13,27H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	684	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120168 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-pent...) Show SMILES CCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C21H27ClN2/c1-2-3-12-19(16-8-5-4-6-9-16)24-14-13-20(24)21(23)17-10-7-11-18(22)15-17/h4-11,15,19-21H,2-3,12-14,23H2,1H3/t19?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	745	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120144 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hexy...) Show SMILES CCCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C22H29ClN2/c1-2-3-5-13-20(17-9-6-4-7-10-17)25-15-14-21(25)22(24)18-11-8-12-19(23)16-18/h4,6-12,16,20-22H,2-3,5,13-15,24H2,1H3/t20?,21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120158 (C-[(R)-C-(3-Chloro-phenyl)-C-((S)-1-di-p-tolylmeth...) Show SMILES Cc1ccc(cc1)C(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccc(C)cc1 Show InChI InChI=1S/C25H27ClN2/c1-17-6-10-19(11-7-17)25(20-12-8-18(2)9-13-20)28-15-14-23(28)24(27)21-4-3-5-22(26)16-21/h3-13,16,23-25H,14-15,27H2,1-2H3/t23-,24+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	801	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120165 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-met...) Show SMILES COc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2O/c1-27-21-14-12-18(13-15-21)23(25)22-16-17-26(22)24(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	865	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120150 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-flu...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(F)c1 Show InChI InChI=1S/C23H23FN2/c24-20-13-7-12-19(16-20)22(25)21-14-15-26(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	997	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120163 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hept...) Show SMILES CCCCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C23H31ClN2/c1-2-3-4-8-14-21(18-10-6-5-7-11-18)26-16-15-22(26)23(25)19-12-9-13-20(24)17-19/h5-7,9-13,17,21-23H,2-4,8,14-16,25H2,1H3/t21?,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120160 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-ethy...) Show SMILES CC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C18H21ClN2/c1-13(14-6-3-2-4-7-14)21-11-10-17(21)18(20)15-8-5-9-16(19)12-15/h2-9,12-13,17-18H,10-11,20H2,1H3/t13?,17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120158 (C-[(R)-C-(3-Chloro-phenyl)-C-((S)-1-di-p-tolylmeth...) Show SMILES Cc1ccc(cc1)C(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccc(C)cc1 Show InChI InChI=1S/C25H27ClN2/c1-17-6-10-19(11-7-17)25(20-12-8-18(2)9-13-20)28-15-14-23(28)24(27)21-4-3-5-22(26)16-21/h3-13,16,23-25H,14-15,27H2,1-2H3/t23-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120156 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-7-12-19(16-20)22(25)21-14-15-26(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120165 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-met...) Show SMILES COc1ccc(cc1)[C@H](N)[C@@H]1CCN1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H26N2O/c1-27-21-14-12-18(13-15-21)23(25)22-16-17-26(22)24(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22-24H,16-17,25H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50120141 (C-[(S)-C-[(S)-1-(1-Butyl-pentyl)-azetidin-2-yl]-C-...) Show SMILES CCCCC(CCCC)N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1 Show InChI InChI=1S/C19H31ClN2/c1-3-5-10-17(11-6-4-2)22-13-12-18(22)19(21)15-8-7-9-16(20)14-15/h7-9,14,17-19H,3-6,10-13,21H2,1-2H3/t18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120161 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(4-chl...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H23ClN2/c24-20-13-11-17(12-14-20)22(25)21-15-16-26(21)23(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,21-23H,15-16,25H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120152 (C-[(R)-C-{(S)-1-[Bis-(4-bromo-phenyl)-methyl]-azet...) Show SMILES N[C@@H]([C@@H]1CCN1C(c1ccc(Br)cc1)c1ccc(Br)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H21Br2ClN2/c24-18-8-4-15(5-9-18)23(16-6-10-19(25)11-7-16)28-13-12-21(28)22(27)17-2-1-3-20(26)14-17/h1-11,14,21-23H,12-13,27H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120138 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hept...) Show SMILES CCCCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C23H31ClN2/c1-2-3-4-8-14-21(18-10-6-5-7-11-18)26-16-15-22(26)23(25)19-12-9-13-20(24)17-19/h5-7,9-13,17,21-23H,2-4,8,14-16,25H2,1H3/t21?,22-,23+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120163 (C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-hept...) Show SMILES CCCCCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C23H31ClN2/c1-2-3-4-8-14-21(18-10-6-5-7-11-18)26-16-15-22(26)23(25)19-12-9-13-20(24)17-19/h5-7,9-13,17,21-23H,2-4,8,14-16,25H2,1H3/t21?,22-,23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120162 (C-((R)-C-(3-Chloro-phenyl)-C-{(S)-1-[1-(3-fluoro-p...) Show SMILES CCCCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1cccc(F)c1 Show InChI InChI=1S/C21H26ClFN2/c1-2-3-10-19(15-6-5-9-18(23)14-15)25-12-11-20(25)21(24)16-7-4-8-17(22)13-16/h4-9,13-14,19-21H,2-3,10-12,24H2,1H3/t19?,20-,21+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120147 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3-tri...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2/c25-24(26,27)20-13-7-12-19(16-20)22(28)21-14-15-29(21)23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21-23H,14-15,28H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair

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