Compile Data Set for Download or QSAR

Found 128 hits Enz. Inhib. hit(s) with all data for entry = 50039524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379458 (CHEMBL2012273) Show SMILES Fc1c(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)cccc1C(F)(F)F Show InChI InChI=1S/C23H21F4N5OS/c24-20-15(2-1-3-19(20)23(25,26)27)10-32-9-6-18-21(32)28-13-29-22(18)33-17-4-7-31(8-5-17)11-16-12-34-14-30-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379439 (CHEMBL2012301) Show SMILES Fc1c(Cn2ccc3c(OC4CCN(Cc5ccccn5)CC4)ncnc23)cccc1C(F)(F)F Show InChI InChI=1S/C25H23F4N5O/c26-22-17(4-3-6-21(22)25(27,28)29)14-34-13-9-20-23(34)31-16-32-24(20)35-19-7-11-33(12-8-19)15-18-5-1-2-10-30-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379455 (CHEMBL2012269) Show SMILES FC(F)(F)c1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1 Show InChI InChI=1S/C23H22F3N5OS/c24-23(25,26)17-3-1-2-16(10-17)11-31-9-6-20-21(31)27-14-28-22(20)32-19-4-7-30(8-5-19)12-18-13-33-15-29-18/h1-3,6,9-10,13-15,19H,4-5,7-8,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379438 (CHEMBL2012300) Show SMILES Fc1c(Cl)cccc1Cn1ccc2c(OC3CCN(Cc4ccccn4)CC3)ncnc12 Show InChI InChI=1S/C24H23ClFN5O/c25-21-6-3-4-17(22(21)26)14-31-13-9-20-23(31)28-16-29-24(20)32-19-7-11-30(12-8-19)15-18-5-1-2-10-27-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379467 (CHEMBL2012293) Show SMILES Cc1cccnc1CN1CCC(CC1)Oc1ncnc2n(Cc3ccccc3)ccc12 Show InChI InChI=1S/C25H27N5O/c1-19-6-5-12-26-23(19)17-29-13-9-21(10-14-29)31-25-22-11-15-30(24(22)27-18-28-25)16-20-7-3-2-4-8-20/h2-8,11-12,15,18,21H,9-10,13-14,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379452 (CHEMBL2012266) Show SMILES Cc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1 Show InChI InChI=1S/C23H25N5OS/c1-17-3-2-4-18(11-17)12-28-10-7-21-22(28)24-15-25-23(21)29-20-5-8-27(9-6-20)13-19-14-30-16-26-19/h2-4,7,10-11,14-16,20H,5-6,8-9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379457 (CHEMBL2012272) Show SMILES Fc1c(Cl)cccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H21ClFN5OS/c23-19-3-1-2-15(20(19)24)10-29-9-6-18-21(29)25-13-26-22(18)30-17-4-7-28(8-5-17)11-16-12-31-14-27-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379465 (CHEMBL2012291) Show SMILES Cc1ccc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)nc1 Show InChI InChI=1S/C25H27N5O/c1-19-7-8-21(26-15-19)17-29-12-9-22(10-13-29)31-25-23-11-14-30(24(23)27-18-28-25)16-20-5-3-2-4-6-20/h2-8,11,14-15,18,22H,9-10,12-13,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379444 (CHEMBL2012246) Show SMILES FC(F)(F)c1nc(OC2CCN(Cc3cscn3)CC2)c2ccn(Cc3ccccc3)c2n1 Show InChI InChI=1S/C23H22F3N5OS/c24-23(25,26)22-28-20-19(8-11-31(20)12-16-4-2-1-3-5-16)21(29-22)32-18-6-9-30(10-7-18)13-17-14-33-15-27-17/h1-5,8,11,14-15,18H,6-7,9-10,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379437 (CHEMBL2012299) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5ccccn5)CC4)ncnc23)c1F Show InChI InChI=1S/C24H23F2N5O/c25-21-6-3-4-17(22(21)26)14-31-13-9-20-23(31)28-16-29-24(20)32-19-7-11-30(12-8-19)15-18-5-1-2-10-27-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379469 (CHEMBL2012295) Show SMILES Fc1ccc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)nc1 Show InChI InChI=1S/C24H24FN5O/c25-19-6-7-20(26-14-19)16-29-11-8-21(9-12-29)31-24-22-10-13-30(23(22)27-17-28-24)15-18-4-2-1-3-5-18/h1-7,10,13-14,17,21H,8-9,11-12,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379471 (CHEMBL2012260) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1 Show InChI InChI=1S/C22H22FN5OS/c23-17-3-1-2-16(10-17)11-28-9-6-20-21(28)24-14-25-22(20)29-19-4-7-27(8-5-19)12-18-13-30-15-26-18/h1-3,6,9-10,13-15,19H,4-5,7-8,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379470 (CHEMBL2012277) Show SMILES C(N1CCC(CC1)Oc1ncnc2n(Cc3ccccc3)ccc12)c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1-3-7-20(8-4-1)17-28-14-11-22(12-15-28)30-25-23-13-16-29(24(23)26-19-27-25)18-21-9-5-2-6-10-21/h1-10,13,16,19,22H,11-12,14-15,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379450 (CHEMBL2012263) Show SMILES Clc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1 Show InChI InChI=1S/C22H22ClN5OS/c23-17-3-1-2-16(10-17)11-28-9-6-20-21(28)24-14-25-22(20)29-19-4-7-27(8-5-19)12-18-13-30-15-26-18/h1-3,6,9-10,13-15,19H,4-5,7-8,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379440 (CHEMBL2012179) Show SMILES Cc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C23H25N5OS/c1-17-11-28(12-18-5-3-2-4-6-18)22-21(17)23(25-15-24-22)29-20-7-9-27(10-8-20)13-19-14-30-16-26-19/h2-6,11,14-16,20H,7-10,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379448 (CHEMBL2012259) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H22FN5OS/c23-20-4-2-1-3-16(20)11-28-10-7-19-21(28)24-14-25-22(19)29-18-5-8-27(9-6-18)12-17-13-30-15-26-17/h1-4,7,10,13-15,18H,5-6,8-9,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379442 (CHEMBL2012181) Show SMILES Clc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C22H22ClN5OS/c23-19-12-28(10-16-4-2-1-3-5-16)21-20(19)22(25-14-24-21)29-18-6-8-27(9-7-18)11-17-13-30-15-26-17/h1-5,12-15,18H,6-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379436 (CHEMBL2012298) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4ccccn4)CC3)ncnc12 Show InChI InChI=1S/C24H24FN5O/c25-22-7-2-1-5-18(22)15-30-14-10-21-23(30)27-17-28-24(21)31-20-8-12-29(13-9-20)16-19-6-3-4-11-26-19/h1-7,10-11,14,17,20H,8-9,12-13,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379466 (CHEMBL2012292) Show SMILES Cc1ccnc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)c1 Show InChI InChI=1S/C25H27N5O/c1-19-7-11-26-21(15-19)17-29-12-8-22(9-13-29)31-25-23-10-14-30(24(23)27-18-28-25)16-20-5-3-2-4-6-20/h2-7,10-11,14-15,18,22H,8-9,12-13,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379459 (CHEMBL2012274) Show SMILES Fc1cccc(F)c1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H21F2N5OS/c23-19-2-1-3-20(24)18(19)11-29-9-6-17-21(29)25-13-26-22(17)30-16-4-7-28(8-5-16)10-15-12-31-14-27-15/h1-3,6,9,12-14,16H,4-5,7-8,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379456 (CHEMBL2012271) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1F Show InChI InChI=1S/C22H21F2N5OS/c23-19-3-1-2-15(20(19)24)10-29-9-6-18-21(29)25-13-26-22(18)30-17-4-7-28(8-5-17)11-16-12-31-14-27-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379464 (CHEMBL2012290) Show SMILES Cc1cccc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)n1 Show InChI InChI=1S/C25H27N5O/c1-19-6-5-9-21(28-19)17-29-13-10-22(11-14-29)31-25-23-12-15-30(24(23)26-18-27-25)16-20-7-3-2-4-8-20/h2-9,12,15,18,22H,10-11,13-14,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379454 (CHEMBL2012268) Show SMILES FC(F)(F)c1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C23H22F3N5OS/c24-23(25,26)20-4-2-1-3-16(20)11-31-10-7-19-21(31)27-14-28-22(19)32-18-5-8-30(9-6-18)12-17-13-33-15-29-17/h1-4,7,10,13-15,18H,5-6,8-9,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379441 (CHEMBL2012180) Show SMILES Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C22H22FN5OS/c23-19-12-28(10-16-4-2-1-3-5-16)21-20(19)22(25-14-24-21)29-18-6-8-27(9-7-18)11-17-13-30-15-26-17/h1-5,12-15,18H,6-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379431 (CHEMBL2012178) Show SMILES Cc1c(C)c2c(OC3CCN(Cc4cscn4)CC3)ncnc2n1Cc1ccccc1 Show InChI InChI=1S/C24H27N5OS/c1-17-18(2)29(12-19-6-4-3-5-7-19)23-22(17)24(26-15-25-23)30-21-8-10-28(11-9-21)13-20-14-31-16-27-20/h3-7,14-16,21H,8-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379453 (CHEMBL2012267) Show SMILES Cc1ccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)cc1 Show InChI InChI=1S/C23H25N5OS/c1-17-2-4-18(5-3-17)12-28-11-8-21-22(28)24-15-25-23(21)29-20-6-9-27(10-7-20)13-19-14-30-16-26-19/h2-5,8,11,14-16,20H,6-7,9-10,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379468 (CHEMBL2012294) Show SMILES Fc1cccc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)n1 Show InChI InChI=1S/C24H24FN5O/c25-22-8-4-7-19(28-22)16-29-12-9-20(10-13-29)31-24-21-11-14-30(23(21)26-17-27-24)15-18-5-2-1-3-6-18/h1-8,11,14,17,20H,9-10,12-13,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379451 (CHEMBL2012265) Show SMILES Cc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C23H25N5OS/c1-17-4-2-3-5-18(17)12-28-11-8-21-22(28)24-15-25-23(21)29-20-6-9-27(10-7-20)13-19-14-30-16-26-19/h2-5,8,11,14-16,20H,6-7,9-10,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379437 (CHEMBL2012299) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5ccccn5)CC4)ncnc23)c1F Show InChI InChI=1S/C24H23F2N5O/c25-21-6-3-4-17(22(21)26)14-31-13-9-20-23(31)28-16-29-24(20)32-19-7-11-30(12-8-19)15-18-5-1-2-10-27-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379448 (CHEMBL2012259) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H22FN5OS/c23-20-4-2-1-3-16(20)11-28-10-7-19-21(28)24-14-25-22(19)29-18-5-8-27(9-6-18)12-17-13-30-15-26-17/h1-4,7,10,13-15,18H,5-6,8-9,11-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379457 (CHEMBL2012272) Show SMILES Fc1c(Cl)cccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H21ClFN5OS/c23-19-3-1-2-15(20(19)24)10-29-9-6-18-21(29)25-13-26-22(18)30-17-4-7-28(8-5-17)11-16-12-31-14-27-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379456 (CHEMBL2012271) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)c1F Show InChI InChI=1S/C22H21F2N5OS/c23-19-3-1-2-15(20(19)24)10-29-9-6-18-21(29)25-13-26-22(18)30-17-4-7-28(8-5-17)11-16-12-31-14-27-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379448 (CHEMBL2012259) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H22FN5OS/c23-20-4-2-1-3-16(20)11-28-10-7-19-21(28)24-14-25-22(19)29-18-5-8-27(9-6-18)12-17-13-30-15-26-17/h1-4,7,10,13-15,18H,5-6,8-9,11-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379436 (CHEMBL2012298) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4ccccn4)CC3)ncnc12 Show InChI InChI=1S/C24H24FN5O/c25-22-7-2-1-5-18(22)15-30-14-10-21-23(30)27-17-28-24(21)31-20-8-12-29(13-9-20)16-19-6-3-4-11-26-19/h1-7,10-11,14,17,20H,8-9,12-13,15-16H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379438 (CHEMBL2012300) Show SMILES Fc1c(Cl)cccc1Cn1ccc2c(OC3CCN(Cc4ccccn4)CC3)ncnc12 Show InChI InChI=1S/C24H23ClFN5O/c25-21-6-3-4-17(22(21)26)14-31-13-9-20-23(31)28-16-29-24(20)32-19-7-11-30(12-8-19)15-18-5-1-2-10-27-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379441 (CHEMBL2012180) Show SMILES Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C22H22FN5OS/c23-19-12-28(10-16-4-2-1-3-5-16)21-20(19)22(25-14-24-21)29-18-6-8-27(9-7-18)11-17-13-30-15-26-17/h1-5,12-15,18H,6-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379458 (CHEMBL2012273) Show SMILES Fc1c(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)cccc1C(F)(F)F Show InChI InChI=1S/C23H21F4N5OS/c24-20-15(2-1-3-19(20)23(25,26)27)10-32-9-6-18-21(32)28-13-29-22(18)33-17-4-7-31(8-5-17)11-16-12-34-14-30-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379459 (CHEMBL2012274) Show SMILES Fc1cccc(F)c1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H21F2N5OS/c23-19-2-1-3-20(24)18(19)11-29-9-6-17-21(29)25-13-26-22(17)30-16-4-7-28(8-5-16)10-15-12-31-14-27-15/h1-3,6,9,12-14,16H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379466 (CHEMBL2012292) Show SMILES Cc1ccnc(CN2CCC(CC2)Oc2ncnc3n(Cc4ccccc4)ccc23)c1 Show InChI InChI=1S/C25H27N5O/c1-19-7-11-26-21(15-19)17-29-12-8-22(9-13-29)31-25-23-10-14-30(24(23)27-18-28-25)16-20-5-3-2-4-6-20/h2-7,10-11,14-15,18,22H,8-9,12-13,16-17H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379451 (CHEMBL2012265) Show SMILES Cc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C23H25N5OS/c1-17-4-2-3-5-18(17)12-28-11-8-21-22(28)24-15-25-23(21)29-20-6-9-27(10-7-20)13-19-14-30-16-26-19/h2-5,8,11,14-16,20H,6-7,9-10,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379436 (CHEMBL2012298) Show SMILES Fc1ccccc1Cn1ccc2c(OC3CCN(Cc4ccccn4)CC3)ncnc12 Show InChI InChI=1S/C24H24FN5O/c25-22-7-2-1-5-18(22)15-30-14-10-21-23(30)27-17-28-24(21)31-20-8-12-29(13-9-20)16-19-6-3-4-11-26-19/h1-7,10-11,14,17,20H,8-9,12-13,15-16H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379437 (CHEMBL2012299) Show SMILES Fc1cccc(Cn2ccc3c(OC4CCN(Cc5ccccn5)CC4)ncnc23)c1F Show InChI InChI=1S/C24H23F2N5O/c25-21-6-3-4-17(22(21)26)14-31-13-9-20-23(31)28-16-29-24(20)32-19-7-11-30(12-8-19)15-18-5-1-2-10-27-18/h1-6,9-10,13,16,19H,7-8,11-12,14-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379458 (CHEMBL2012273) Show SMILES Fc1c(Cn2ccc3c(OC4CCN(Cc5cscn5)CC4)ncnc23)cccc1C(F)(F)F Show InChI InChI=1S/C23H21F4N5OS/c24-20-15(2-1-3-19(20)23(25,26)27)10-32-9-6-18-21(32)28-13-29-22(18)33-17-4-7-31(8-5-17)11-16-12-34-14-30-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379442 (CHEMBL2012181) Show SMILES Clc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C22H22ClN5OS/c23-19-12-28(10-16-4-2-1-3-5-16)21-20(19)22(25-14-24-21)29-18-6-8-27(9-7-18)11-17-13-30-15-26-17/h1-5,12-15,18H,6-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379440 (CHEMBL2012179) Show SMILES Cc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C23H25N5OS/c1-17-11-28(12-18-5-3-2-4-6-18)22-21(17)23(25-15-24-22)29-20-7-9-27(10-8-20)13-19-14-30-16-26-19/h2-6,11,14-16,20H,7-10,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379457 (CHEMBL2012272) Show SMILES Fc1c(Cl)cccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H21ClFN5OS/c23-19-3-1-2-15(20(19)24)10-29-9-6-18-21(29)25-13-26-22(18)30-17-4-7-28(8-5-17)11-16-12-31-14-27-16/h1-3,6,9,12-14,17H,4-5,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.5 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379449 (CHEMBL2012262) Show SMILES Clc1ccccc1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc12 Show InChI InChI=1S/C22H22ClN5OS/c23-20-4-2-1-3-16(20)11-28-10-7-19-21(28)24-14-25-22(19)29-18-5-8-27(9-6-18)12-17-13-30-15-26-17/h1-4,7,10,13-15,18H,5-6,8-9,11-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379440 (CHEMBL2012179) Show SMILES Cc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C23H25N5OS/c1-17-11-28(12-18-5-3-2-4-6-18)22-21(17)23(25-15-24-22)29-20-7-9-27(10-8-20)13-19-14-30-16-26-19/h2-6,11,14-16,20H,7-10,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379441 (CHEMBL2012180) Show SMILES Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 Show InChI InChI=1S/C22H22FN5OS/c23-19-12-28(10-16-4-2-1-3-5-16)21-20(19)22(25-14-24-21)29-18-6-8-27(9-7-18)11-17-13-30-15-26-17/h1-5,12-15,18H,6-11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NaV1.7 channel by patchXpress assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379431 (CHEMBL2012178) Show SMILES Cc1c(C)c2c(OC3CCN(Cc4cscn4)CC3)ncnc2n1Cc1ccccc1 Show InChI InChI=1S/C24H27N5OS/c1-17-18(2)29(12-19-6-4-3-5-7-19)23-22(17)24(26-15-25-23)30-21-8-10-28(11-9-21)13-20-14-31-16-27-20/h3-7,14-16,21H,8-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at 20% inactivated human NaV1.7 channel by electrophysiology-based screening assay				Bioorg Med Chem Lett 22: 2052-62 (2012) Article DOI: 10.1016/j.bmcl.2012.01.015 BindingDB Entry DOI: 10.7270/Q2HM59GC
					More data for this Ligand-Target Pair

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