Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50039997 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387549
(CHEMBL2057693)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C28H34N2O4/c1-29(26(32)7-4-20-9-13-34-18-20)22-8-10-28(33)25-14-21-5-6-23(31)15-24(21)27(28,16-22)11-12-30(25)17-19-2-3-19/h4-7,9,13,15,18-19,22,25,31,33H,2-3,8,10-12,14,16-17H2,1H3/b7-4+/t22-,25-,27-,28-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50274519
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:8.24.7:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(32)9-4-18-10-13-33-16-18)21-7-6-20-22-14-19-5-8-23(31)26-25(19)28(20,27(21)34-26)11-12-30(22)15-17-2-3-17/h4-5,8-10,13,16-17,20-22,27,31H,2-3,6-7,11-12,14-15H2,1H3/b9-4+/t20-,21+,22+,27-,28-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387549
(CHEMBL2057693)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C28H34N2O4/c1-29(26(32)7-4-20-9-13-34-18-20)22-8-10-28(33)25-14-21-5-6-23(31)15-24(21)27(28,16-22)11-12-30(25)17-19-2-3-19/h4-7,9,13,15,18-19,22,25,31,33H,2-3,8,10-12,14,16-17H2,1H3/b7-4+/t22-,25-,27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50274519
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:8.24.7:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(32)9-4-18-10-13-33-16-18)21-7-6-20-22-14-19-5-8-23(31)26-25(19)28(20,27(21)34-26)11-12-30(22)15-17-2-3-17/h4-5,8-10,13,16-17,20-22,27,31H,2-3,6-7,11-12,14-15H2,1H3/b9-4+/t20-,21+,22+,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387549
(CHEMBL2057693)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C28H34N2O4/c1-29(26(32)7-4-20-9-13-34-18-20)22-8-10-28(33)25-14-21-5-6-23(31)15-24(21)27(28,16-22)11-12-30(25)17-19-2-3-19/h4-7,9,13,15,18-19,22,25,31,33H,2-3,8,10-12,14,16-17H2,1H3/b7-4+/t22-,25-,27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50274482
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-1...)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4cccc5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:9.24.8:17.19.18,THB:6:5:9.24.8:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(31)8-7-19-10-14-33-17-19)21-9-11-28(32)23-15-20-3-2-4-22-25(20)27(28,26(21)34-22)12-13-30(23)16-18-5-6-18/h2-4,7-8,10,14,17-18,21,23,26,32H,5-6,9,11-13,15-16H2,1H3/b8-7+/t21-,23-,26+,27+,28-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387553
(CHEMBL2057691)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:9| Show InChI InChI=1S/C28H38N2O3/c1-29(26(31)9-8-21-11-15-33-19-21)23-10-12-28(32)25-16-22-4-2-3-5-24(22)27(28,17-23)13-14-30(25)18-20-6-7-20/h8-9,11,15,19-20,23,25,32H,2-7,10,12-14,16-18H2,1H3/b9-8+/t23-,25-,27-,28-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50274519
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:8.24.7:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(32)9-4-18-10-13-33-16-18)21-7-6-20-22-14-19-5-8-23(31)26-25(19)28(20,27(21)34-26)11-12-30(22)15-17-2-3-17/h4-5,8-10,13,16-17,20-22,27,31H,2-3,6-7,11-12,14-15H2,1H3/b9-4+/t20-,21+,22+,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387554
(CHEMBL2057692)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:8| Show InChI InChI=1S/C28H38N2O2/c1-29(27(31)11-8-21-12-15-32-19-21)23-9-10-25-26-16-22-4-2-3-5-24(22)28(25,17-23)13-14-30(26)18-20-6-7-20/h8,11-12,15,19-20,23,25-26H,2-7,9-10,13-14,16-18H2,1H3/b11-8+/t23-,25+,26-,28-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387554
(CHEMBL2057692)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:8| Show InChI InChI=1S/C28H38N2O2/c1-29(27(31)11-8-21-12-15-32-19-21)23-9-10-25-26-16-22-4-2-3-5-24(22)28(25,17-23)13-14-30(26)18-20-6-7-20/h8,11-12,15,19-20,23,25-26H,2-7,9-10,13-14,16-18H2,1H3/b11-8+/t23-,25+,26-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387553
(CHEMBL2057691)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:9| Show InChI InChI=1S/C28H38N2O3/c1-29(26(31)9-8-21-11-15-33-19-21)23-10-12-28(32)25-16-22-4-2-3-5-24(22)27(28,17-23)13-14-30(25)18-20-6-7-20/h8-9,11,15,19-20,23,25,32H,2-7,10,12-14,16-18H2,1H3/b9-8+/t23-,25-,27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 83.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50274482
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-1...)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4cccc5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:9.24.8:17.19.18,THB:6:5:9.24.8:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(31)8-7-19-10-14-33-17-19)21-9-11-28(32)23-15-20-3-2-4-22-25(20)27(28,26(21)34-22)12-13-30(23)16-18-5-6-18/h2-4,7-8,10,14,17-18,21,23,26,32H,5-6,9,11-13,15-16H2,1H3/b8-7+/t21-,23-,26+,27+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387554
(CHEMBL2057692)Show SMILES CN([C@@H]1CC[C@H]2[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:8| Show InChI InChI=1S/C28H38N2O2/c1-29(27(31)11-8-21-12-15-32-19-21)23-9-10-25-26-16-22-4-2-3-5-24(22)28(25,17-23)13-14-30(26)18-20-6-7-20/h8,11-12,15,19-20,23,25-26H,2-7,9-10,13-14,16-18H2,1H3/b11-8+/t23-,25+,26-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387553
(CHEMBL2057691)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:9| Show InChI InChI=1S/C28H38N2O3/c1-29(26(31)9-8-21-11-15-33-19-21)23-10-12-28(32)25-16-22-4-2-3-5-24(22)27(28,17-23)13-14-30(25)18-20-6-7-20/h8-9,11,15,19-20,23,25,32H,2-7,10,12-14,16-18H2,1H3/b9-8+/t23-,25-,27-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 308 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387552
(CHEMBL2057690)Show SMILES CN[C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1 |r,t:9,THB:19:18:5:9.10.8| Show InChI InChI=1S/C21H34N2O/c1-22-17-8-9-21(24)19-12-16-4-2-3-5-18(16)20(21,13-17)10-11-23(19)14-15-6-7-15/h15,17,19,22,24H,2-14H2,1H3/t17-,19-,20-,21-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 352 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387551
(CHEMBL2057689)Show SMILES O[C@@]12CCC(=O)C[C@@]11CCN(CC3CC3)[C@@H]2CC2=C1CCCC2 |r,c:20,THB:11:10:1:17.18.16| Show InChI InChI=1S/C20H29NO2/c22-16-7-8-20(23)18-11-15-3-1-2-4-17(15)19(20,12-16)9-10-21(18)13-14-5-6-14/h14,18,23H,1-13H2/t18-,19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 391 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387551
(CHEMBL2057689)Show SMILES O[C@@]12CCC(=O)C[C@@]11CCN(CC3CC3)[C@@H]2CC2=C1CCCC2 |r,c:20,THB:11:10:1:17.18.16| Show InChI InChI=1S/C20H29NO2/c22-16-7-8-20(23)18-11-15-3-1-2-4-17(15)19(20,12-16)9-10-21(18)13-14-5-6-14/h14,18,23H,1-13H2/t18-,19-,20-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 787 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387551
(CHEMBL2057689)Show SMILES O[C@@]12CCC(=O)C[C@@]11CCN(CC3CC3)[C@@H]2CC2=C1CCCC2 |r,c:20,THB:11:10:1:17.18.16| Show InChI InChI=1S/C20H29NO2/c22-16-7-8-20(23)18-11-15-3-1-2-4-17(15)19(20,12-16)9-10-21(18)13-14-5-6-14/h14,18,23H,1-13H2/t18-,19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 939 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387552
(CHEMBL2057690)Show SMILES CN[C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1 |r,t:9,THB:19:18:5:9.10.8| Show InChI InChI=1S/C21H34N2O/c1-22-17-8-9-21(24)19-12-16-4-2-3-5-18(16)20(21,13-17)10-11-23(19)14-15-6-7-15/h15,17,19,22,24H,2-14H2,1H3/t17-,19-,20-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387552
(CHEMBL2057690)Show SMILES CN[C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1 |r,t:9,THB:19:18:5:9.10.8| Show InChI InChI=1S/C21H34N2O/c1-22-17-8-9-21(24)19-12-16-4-2-3-5-18(16)20(21,13-17)10-11-23(19)14-15-6-7-15/h15,17,19,22,24H,2-14H2,1H3/t17-,19-,20-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50274482
((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-1...)Show SMILES CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4cccc5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |r,TLB:4:5:9.24.8:17.19.18,THB:6:5:9.24.8:17.19.18| Show InChI InChI=1S/C28H32N2O4/c1-29(24(31)8-7-19-10-14-33-17-19)21-9-11-28(32)23-15-20-3-2-4-22-25(20)27(28,26(21)34-22)12-13-30(23)16-18-5-6-18/h2-4,7-8,10,14,17-18,21,23,26,32H,5-6,9,11-13,15-16H2,1H3/b8-7+/t21-,23-,26+,27+,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50387550
(CHEMBL2057688)Show SMILES CN([C@@H]1CC[C@H]2CN(CC3CC3)CC[C@@H]2C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C21H30N2O2/c1-22(21(24)7-4-17-9-11-25-15-17)20-6-5-19-14-23(13-16-2-3-16)10-8-18(19)12-20/h4,7,9,11,15-16,18-20H,2-3,5-6,8,10,12-14H2,1H3/b7-4+/t18-,19+,20-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50387550
(CHEMBL2057688)Show SMILES CN([C@@H]1CC[C@H]2CN(CC3CC3)CC[C@@H]2C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C21H30N2O2/c1-22(21(24)7-4-17-9-11-25-15-17)20-6-5-19-14-23(13-16-2-3-16)10-8-18(19)12-20/h4,7,9,11,15-16,18-20H,2-3,5-6,8,10,12-14H2,1H3/b7-4+/t18-,19+,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50387550
(CHEMBL2057688)Show SMILES CN([C@@H]1CC[C@H]2CN(CC3CC3)CC[C@@H]2C1)C(=O)\C=C\c1ccoc1 |r| Show InChI InChI=1S/C21H30N2O2/c1-22(21(24)7-4-17-9-11-25-15-17)20-6-5-19-14-23(13-16-2-3-16)10-8-18(19)12-20/h4,7,9,11,15-16,18-20H,2-3,5-6,8,10,12-14H2,1H3/b7-4+/t18-,19+,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellum |
Bioorg Med Chem Lett 22: 5071-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.122
BindingDB Entry DOI: 10.7270/Q2DB82XR |
More data for this
Ligand-Target Pair | |
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