Compile Data Set for Download or QSAR

Found 170 hits Enz. Inhib. hit(s) with all data for entry = 1878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349368 (US10207991, Ex. Cpd. No. 11 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349518 (US10207991, Ex. Cpd. No. 34 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1 Show InChI InChI=1S/C21H26FNO2/c1-21(2,10-9-15-5-7-18(22)8-6-15)23-13-16-11-19(24-3)20(25-4)12-17(16)14-23/h5-8,11-12H,9-10,13-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349505 (US10207991, Ex. Cpd. No. 20 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349505 (US10207991, Ex. Cpd. No. 20 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349569 (US10207991, Ex. Cpd. No. 87 | US10611728, Example ...) Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O Show InChI InChI=1S/C24H33NO4S/c1-17(2)16-29-23-12-18(6-9-22(23)26)10-11-24(3,4)25-14-19-7-8-21(30(5,27)28)13-20(19)15-25/h6-9,12-13,17,26H,10-11,14-16H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349570 (US10207991, Ex. Cpd. No. 88 | US10611728, Example ...) Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O Show InChI InChI=1S/C23H30FNO2/c1-16(2)15-27-22-12-17(8-9-21(22)26)10-11-23(3,4)25-13-18-6-5-7-20(24)19(18)14-25/h5-9,12,16,26H,10-11,13-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349578 (US10207991, Ex. Cpd. No. 103 | US10611728, Example...) Show SMILES COc1cccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)c1 Show InChI InChI=1S/C21H27NO3S/c1-21(2,11-10-16-6-5-7-19(12-16)25-3)22-14-17-8-9-20(26(4,23)24)13-18(17)15-22/h5-9,12-13H,10-11,14-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349365 (US10207991, Ex. Cpd. No. 10 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3OCOc3cc2C1 |r| Show InChI InChI=1S/C19H19Cl2NO2/c1-12(2-3-13-4-5-16(20)17(21)6-13)22-9-14-7-18-19(24-11-23-18)8-15(14)10-22/h4-8,12H,2-3,9-11H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349387 (US10207991, Ex. Cpd. No. 18 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3ccccc3cc2C1 |r| Show InChI InChI=1S/C22H21Cl2N/c1-15(6-7-16-8-9-21(23)22(24)10-16)25-13-19-11-17-4-2-3-5-18(17)12-20(19)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3/t15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349478 (US10207991, Ex. Cpd. No. 19 | US10611728, Example ...) Show SMILES CC(CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc3ccccc3c2C1 Show InChI InChI=1S/C22H21Cl2N/c1-15(6-7-16-8-11-21(23)22(24)12-16)25-13-18-10-9-17-4-2-3-5-19(17)20(18)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349577 (US10207991, Ex. Cpd. No. 102 | US10611728, Example...) Show SMILES COc1ccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO3S/c1-21(2,12-11-16-5-8-19(25-3)9-6-16)22-14-17-7-10-20(26(4,23)24)13-18(17)15-22/h5-10,13H,11-12,14-15H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349519 (US10207991, Ex. Cpd. No. 35 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2ccc(F)cc2C1 Show InChI InChI=1S/C19H21F2N/c1-19(2,10-9-14-3-6-17(20)7-4-14)22-12-15-5-8-18(21)11-16(15)13-22/h3-8,11H,9-10,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349307 (US10207991, Ex. Cpd. No. 4 | US10611728, Example C...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc(cc2C1)C(F)(F)F |r| Show InChI InChI=1S/C19H18Cl2F3N/c1-12(2-3-13-4-7-17(20)18(21)8-13)25-10-14-5-6-16(19(22,23)24)9-15(14)11-25/h4-9,12H,2-3,10-11H2,1H3/t12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349551 (US10207991, Ex. Cpd. No. 66 | US10611728, Example ...) Show SMILES CC(C)(C)Oc1cc(CCC(C)(C)N2Cc3cccc(c3C2)S(C)(=O)=O)ccc1O Show InChI InChI=1S/C24H33NO4S/c1-23(2,3)29-21-14-17(10-11-20(21)26)12-13-24(4,5)25-15-18-8-7-9-22(19(18)16-25)30(6,27)28/h7-11,14,26H,12-13,15-16H2,1-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349559 (US10207991, Ex. Cpd. No. 76 | US10611728, Example ...) Show SMILES COc1cc(CCC(C)(C)N2Cc3cccc(C(=O)N4CCNCC4)c3C2)ccc1O Show InChI InChI=1S/C25H33N3O3/c1-25(2,10-9-18-7-8-22(29)23(15-18)31-3)28-16-19-5-4-6-20(21(19)17-28)24(30)27-13-11-26-12-14-27/h4-8,15,26,29H,9-14,16-17H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349316 (US10207991, Ex. Cpd. No. 5 | US10611728, Example C...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc(Cl)c(Cl)cc2C1 |r| Show InChI InChI=1S/C18H17Cl4N/c1-11(2-3-12-4-5-15(19)16(20)6-12)23-9-13-7-17(21)18(22)8-14(13)10-23/h4-8,11H,2-3,9-10H2,1H3/t11-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349517 (US10207991, Ex. Cpd. No. 33 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2cccc(F)c2C1 Show InChI InChI=1S/C19H21F2N/c1-19(2,11-10-14-6-8-16(20)9-7-14)22-12-15-4-3-5-18(21)17(15)13-22/h3-9H,10-13H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349325 (US10207991, Ex. Cpd. No. 9 | US10611728, Example C...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cccc(F)c2C1 |r| Show InChI InChI=1S/C18H18Cl2FN/c1-12(5-6-13-7-8-16(19)17(20)9-13)22-10-14-3-2-4-18(21)15(14)11-22/h2-4,7-9,12H,5-6,10-11H2,1H3/t12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349519 (US10207991, Ex. Cpd. No. 35 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2ccc(F)cc2C1 Show InChI InChI=1S/C19H21F2N/c1-19(2,10-9-14-3-6-17(20)7-4-14)22-12-15-5-8-18(21)11-16(15)13-22/h3-8,11H,9-10,12-13H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349516 (US10207991, Ex. Cpd. No. 31 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(O)c(OC(F)(F)F)c1)N1Cc2ccc(F)cc2C1 |r| Show InChI InChI=1S/C19H19F4NO2/c1-12(24-10-14-5-6-16(20)9-15(14)11-24)2-3-13-4-7-17(25)18(8-13)26-19(21,22)23/h4-9,12,25H,2-3,10-11H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349520 (US10207991, Ex. Cpd. No. 36 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2cc3OCOc3cc2C1 Show InChI InChI=1S/C20H22FNO2/c1-20(2,8-7-14-3-5-17(21)6-4-14)22-11-15-9-18-19(24-13-23-18)10-16(15)12-22/h3-6,9-10H,7-8,11-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349509 (US10207991, Ex. Cpd. No. 24 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(O)c(OC(F)(F)F)c1)N1Cc2cc3OCOc3cc2C1 |r| Show InChI InChI=1S/C20H20F3NO4/c1-12(2-3-13-4-5-16(25)17(6-13)28-20(21,22)23)24-9-14-7-18-19(27-11-26-18)8-15(14)10-24/h4-8,12,25H,2-3,9-11H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349365 (US10207991, Ex. Cpd. No. 10 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3OCOc3cc2C1 |r| Show InChI InChI=1S/C19H19Cl2NO2/c1-12(2-3-13-4-5-16(20)17(21)6-13)22-9-14-7-18-19(24-11-23-18)8-15(14)10-22/h4-8,12H,2-3,9-11H2,1H3/t12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349520 (US10207991, Ex. Cpd. No. 36 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2cc3OCOc3cc2C1 Show InChI InChI=1S/C20H22FNO2/c1-20(2,8-7-14-3-5-17(21)6-4-14)22-11-15-9-18-19(24-13-23-18)10-16(15)12-22/h3-6,9-10H,7-8,11-13H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349510 (US10207991, Ex. Cpd. No. 25 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CC[C@@H](C)N2Cc3cc4OCOc4cc3C2)ccc1O |r| Show InChI InChI=1S/C22H27NO4/c1-14(2)27-20-8-16(6-7-19(20)24)5-4-15(3)23-11-17-9-21-22(26-13-25-21)10-18(17)12-23/h6-10,14-15,24H,4-5,11-13H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349526 (US10207991, Ex. Cpd. No. 42 | US10611728, Example ...) Show SMILES CC(C)Oc1ccc(CCC(C)(C)N2Cc3ccc(F)cc3C2)cc1OC(C)C Show InChI InChI=1S/C25H34FNO2/c1-17(2)28-23-10-7-19(13-24(23)29-18(3)4)11-12-25(5,6)27-15-20-8-9-22(26)14-21(20)16-27/h7-10,13-14,17-18H,11-12,15-16H2,1-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349572 (US10207991, Ex. Cpd. No. 96 | US10611728, Example ...) Show SMILES CC(=O)Oc1ccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)cc1OC(C)(C)C Show InChI InChI=1S/C26H35NO5S/c1-18(28)31-23-11-8-19(14-24(23)32-25(2,3)4)12-13-26(5,6)27-16-20-9-10-22(33(7,29)30)15-21(20)17-27/h8-11,14-15H,12-13,16-17H2,1-7H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349546 (US10207991, Ex. Cpd. No. 61 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(O)c(OC(F)(F)F)c1)N1Cc2ccc(cc2C1)S(C)(=O)=O Show InChI InChI=1S/C21H24F3NO4S/c1-20(2,9-8-14-4-7-18(26)19(10-14)29-21(22,23)24)25-12-15-5-6-17(30(3,27)28)11-16(15)13-25/h4-7,10-11,26H,8-9,12-13H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349518 (US10207991, Ex. Cpd. No. 34 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1 Show InChI InChI=1S/C21H26FNO2/c1-21(2,10-9-15-5-7-18(22)8-6-15)23-13-16-11-19(24-3)20(25-4)12-17(16)14-23/h5-8,11-12H,9-10,13-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349524 (US10207991, Ex. Cpd. No. 40 | US10611728, Example ...) Show SMILES CC(C)Oc1ccc(CC[C@@H](C)N2Cc3cc4OCOc4cc3C2)cc1OC(C)C |r| Show InChI InChI=1S/C25H33NO4/c1-16(2)29-22-9-8-19(10-25(22)30-17(3)4)7-6-18(5)26-13-20-11-23-24(28-15-27-23)12-21(20)14-26/h8-12,16-18H,6-7,13-15H2,1-5H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349511 (US10207991, Ex. Cpd. No. 26 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CC[C@@H](C)N2Cc3cccc(F)c3C2)ccc1O |r| Show InChI InChI=1S/C21H26FNO2/c1-14(2)25-21-11-16(9-10-20(21)24)8-7-15(3)23-12-17-5-4-6-19(22)18(17)13-23/h4-6,9-11,14-15,24H,7-8,12-13H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349552 (US10207991, Ex. Cpd. No. 67 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(O)c(OC(F)(F)F)c1)N1Cc2cccc(c2C1)S(C)(=O)=O Show InChI InChI=1S/C21H24F3NO4S/c1-20(2,10-9-14-7-8-17(26)18(11-14)29-21(22,23)24)25-12-15-5-4-6-19(16(15)13-25)30(3,27)28/h4-8,11,26H,9-10,12-13H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349547 (US10207991, Ex. Cpd. No. 62 | US10611728, Example ...) Show SMILES CC(C)(C)Oc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O Show InChI InChI=1S/C24H33NO4S/c1-23(2,3)29-22-13-17(7-10-21(22)26)11-12-24(4,5)25-15-18-8-9-20(30(6,27)28)14-19(18)16-25/h7-10,13-14,26H,11-12,15-16H2,1-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349549 (US10207991, Ex. Cpd. No. 64 | US10611728, Example ...) Show SMILES COc1cc(CCC(C)(C)N2Cc3cccc(c3C2)S(C)(=O)=O)ccc1O Show InChI InChI=1S/C21H27NO4S/c1-21(2,11-10-15-8-9-18(23)19(12-15)26-3)22-13-16-6-5-7-20(17(16)14-22)27(4,24)25/h5-9,12,23H,10-11,13-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349524 (US10207991, Ex. Cpd. No. 40 | US10611728, Example ...) Show SMILES CC(C)Oc1ccc(CC[C@@H](C)N2Cc3cc4OCOc4cc3C2)cc1OC(C)C |r| Show InChI InChI=1S/C25H33NO4/c1-16(2)29-22-9-8-19(10-25(22)30-17(3)4)7-6-18(5)26-13-20-11-23-24(28-15-27-23)12-21(20)14-26/h8-12,16-18H,6-7,13-15H2,1-5H3/t18-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349555 (US10207991, Ex. Cpd. No. 70 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O Show InChI InChI=1S/C23H31NO4S/c1-16(2)28-22-12-17(6-9-21(22)25)10-11-23(3,4)24-14-18-7-8-20(29(5,26)27)13-19(18)15-24/h6-9,12-13,16,25H,10-11,14-15H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349521 (US10207991, Ex. Cpd. No. 37 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CC[C@@H](C)N2Cc3ccc(F)cc3C2)ccc1O |r| Show InChI InChI=1S/C21H26FNO2/c1-14(2)25-21-10-16(6-9-20(21)24)5-4-15(3)23-12-17-7-8-19(22)11-18(17)13-23/h6-11,14-15,24H,4-5,12-13H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349513 (US10207991, Ex. Cpd. No. 28 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O Show InChI InChI=1S/C22H28FNO2/c1-15(2)26-21-12-16(8-9-20(21)25)10-11-22(3,4)24-13-17-6-5-7-19(23)18(17)14-24/h5-9,12,15,25H,10-11,13-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349576 (US10207991, Ex. Cpd. No. 101 | US10611728, Example...) Show SMILES COc1ccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)cc1OC Show InChI InChI=1S/C22H29NO4S/c1-22(2,11-10-16-6-9-20(26-3)21(12-16)27-4)23-14-17-7-8-19(28(5,24)25)13-18(17)15-23/h6-9,12-13H,10-11,14-15H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349506 (US10207991, Ex. Cpd. No. 21 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(F)cc1)N1Cc2cccc(F)c2C1 |r| Show InChI InChI=1S/C18H19F2N/c1-13(5-6-14-7-9-16(19)10-8-14)21-11-15-3-2-4-18(20)17(15)12-21/h2-4,7-10,13H,5-6,11-12H2,1H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349514 (US10207991, Ex. Cpd. No. 29 | US10611728, Example ...) Show SMILES CC(C)Oc1cc(CCC(C)(C)N2Cc3cc4OCOc4cc3C2)ccc1O Show InChI InChI=1S/C23H29NO4/c1-15(2)28-20-9-16(5-6-19(20)25)7-8-23(3,4)24-12-17-10-21-22(27-14-26-21)11-18(17)13-24/h5-6,9-11,15,25H,7-8,12-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349508 (US10207991, Ex. Cpd. No. 23 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(F)cc1)N1Cc2cc3OCOc3cc2C1 |r| Show InChI InChI=1S/C19H20FNO2/c1-13(2-3-14-4-6-17(20)7-5-14)21-10-15-8-18-19(23-12-22-18)9-16(15)11-21/h4-9,13H,2-3,10-12H2,1H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349368 (US10207991, Ex. Cpd. No. 11 | US10611728, Example ...) Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349583 (US10207991, Ex. Cpd. No. 108 | US10611728, Example...) Show SMILES CC(C)(CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc(cc2C1)N1CCNCC1 Show InChI InChI=1S/C23H29Cl2N3/c1-23(2,8-7-17-3-6-21(24)22(25)13-17)28-15-18-4-5-20(14-19(18)16-28)27-11-9-26-10-12-27/h3-6,13-14,26H,7-12,15-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349508 (US10207991, Ex. Cpd. No. 23 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(F)cc1)N1Cc2cc3OCOc3cc2C1 |r| Show InChI InChI=1S/C19H20FNO2/c1-13(2-3-14-4-6-17(20)7-5-14)21-10-15-8-18-19(23-12-22-18)9-16(15)11-21/h4-9,13H,2-3,10-12H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349548 (US10207991, Ex. Cpd. No. 63 | US10611728, Example ...) Show SMILES C[C@H](CCc1ccc(O)c(OC(C)(C)C)c1)N1Cc2ccc(cc2C1)S(C)(=O)=O |r| Show InChI InChI=1S/C23H31NO4S/c1-16(6-7-17-8-11-21(25)22(12-17)28-23(2,3)4)24-14-18-9-10-20(29(5,26)27)13-19(18)15-24/h8-13,16,25H,6-7,14-15H2,1-5H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349537 (US10207991, Ex. Cpd. No. 53 | US10611728, Example ...) Show SMILES COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O Show InChI InChI=1S/C20H24FNO2/c1-20(2,10-9-14-7-8-18(23)19(11-14)24-3)22-12-15-5-4-6-17(21)16(15)13-22/h4-8,11,23H,9-10,12-13H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349325 (US10207991, Ex. Cpd. No. 9 | US10611728, Example C...) Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cccc(F)c2C1 |r| Show InChI InChI=1S/C18H18Cl2FN/c1-12(5-6-13-7-8-16(19)17(20)9-13)22-10-14-3-2-4-18(21)15(14)11-22/h2-4,7-9,12H,5-6,10-11H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM349538 (US10207991, Ex. Cpd. No. 54 | US10611728, Example ...) Show SMILES CC(C)(CCc1ccc(O)c(OC(F)(F)F)c1)N1Cc2cccc(F)c2C1 Show InChI InChI=1S/C20H21F4NO2/c1-19(2,25-11-14-4-3-5-16(21)15(14)12-25)9-8-13-6-7-17(26)18(10-13)27-20(22,23)24/h3-7,10,26H,8-9,11-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM349522 (US10207991, Ex. Cpd. No. 38 | US10611728, Example ...) Show SMILES CC(C)Oc1ccc(CC[C@@H](C)N2Cc3ccc(F)cc3C2)cc1OC(C)C |r| Show InChI InChI=1S/C24H32FNO2/c1-16(2)27-23-11-8-19(12-24(23)28-17(3)4)7-6-18(5)26-14-20-9-10-22(25)13-21(20)15-26/h8-13,16-18H,6-7,14-15H2,1-5H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
COGNITION THERAPEUTICS, INC. US Patent					Assay Description The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...				US Patent US10207991 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JRG
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 170 total )  |  Next  |  Last  >>

Jump to: