Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125066 (CHEMBL165889 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125065 (CHEMBL165687 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125062 (CHEMBL162485 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125063 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125064 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50119355 (2-{4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125074 (CHEMBL444865 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125057 (CHEMBL351187 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125072 (CHEMBL166299 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125073 (CHEMBL164199 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125076 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50113425 (2-{4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125067 (CHEMBL351007 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125070 (CHEMBL423252 | N-{5-[1-(3,4-Bis-difluoromethoxy-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125060 (1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125068 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125059 (CHEMBL163311 | {5-[1-(3,4-Bis-difluoromethoxy-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125058 (CHEMBL162870 | N-{5-[1-(3,4-Bis-difluoromethoxy-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125071 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125075 (4-[2-[3,4-di(difluoromethoxy)phenyl]-2-(6-tetrahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125069 (5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50125061 (CHEMBL165773 | N-{5-[1-(3,4-Bis-difluoromethoxy-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in... | Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G | |||||||||||
More data for this Ligand-Target Pair |