Compile Data Set for Download or QSAR

Found 296 hits Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019866 (CHEMBL3286930) Show SMILES O=C(OC[C@H](C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 |r| Show InChI InChI=1S/C40H42N6O2/c47-39(32-21-25-44(26-22-32)40-43-33-15-7-9-17-35(33)45(40)27-29-11-3-1-4-12-29)48-28-37(30-19-23-41-24-20-30)46-36-18-10-8-16-34(36)42-38(46)31-13-5-2-6-14-31/h1-18,30,32,37,41H,19-28H2/t37-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to PDE-delta (unknown origin) by SPR analysis				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50529751 (CHEMBL4472979 | US10913710, Compound 16) Show SMILES CNc1nccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)n1 Show InChI InChI=1S/C30H39ClN6O4S2/c1-32-30-34-19-16-26(35-30)22-36(20-24-14-17-33-18-15-24)42(38,39)28-10-12-29(13-11-28)43(40,41)37(27-4-2-3-5-27)21-23-6-8-25(31)9-7-23/h6-13,16,19,24,27,33H,2-5,14-15,17-18,20-22H2,1H3,(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	0.203	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to PDEdelta (unknown origin)				Eur J Med Chem 163: 597-609 (2019) Article DOI: 10.1016/j.ejmech.2018.12.018 BindingDB Entry DOI: 10.7270/Q2FF3WTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50529751 (CHEMBL4472979 | US10913710, Compound 16) Show SMILES CNc1nccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)n1 Show InChI InChI=1S/C30H39ClN6O4S2/c1-32-30-34-19-16-26(35-30)22-36(20-24-14-17-33-18-15-24)42(38,39)28-10-12-29(13-11-28)43(40,41)37(27-4-2-3-5-27)21-23-6-8-25(31)9-7-23/h6-13,16,19,24,27,33H,2-5,14-15,17-18,20-22H2,1H3,(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	0.203	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity to PDEdelta (unknown origin)				Eur J Med Chem 163: 597-609 (2019) Article DOI: 10.1016/j.ejmech.2018.12.018 BindingDB Entry DOI: 10.7270/Q2FF3WTS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249988 (CHEMBL4061005) Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019865 (CHEMBL3286929) Show SMILES C(Oc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1)[C@H](C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1 |r| Show InChI InChI=1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31-13-5-2-6-14-31/h1-22,30,38,41H,23-28H2/t38-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to PDE-delta (unknown origin) by time-resolved fluorescence anisotropic analysis				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249988 (CHEMBL4061005) Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249988 (CHEMBL4061005) Show SMILES Cc1n(nc2c1c(C)nn(CCC(=O)N1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C36H36FN7O3/c1-22-12-14-26(15-13-22)44-24(3)32-23(2)39-42(36(47)33(32)40-44)21-18-31(45)41-19-16-25(17-20-41)43-34(27-8-4-6-10-29(27)37)38-30-11-7-5-9-28(30)35(43)46/h4-15,25,34,38H,16-21H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249989 (CHEMBL1387422) Show SMILES CC(CNC(=O)CCCn1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C27H31N5O2/c1-18-12-14-23(15-13-18)32-21(4)25-20(3)29-31(27(34)26(25)30-32)16-8-11-24(33)28-17-19(2)22-9-6-5-7-10-22/h5-7,9-10,12-15,19H,8,11,16-17H2,1-4H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249992 (CHEMBL4090695) Show SMILES Fc1ccccc1[C@@H]1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1[C@@H](Nc2ccccc2C1=O)c1ccccc1F |r| Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2/t32-,33-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249979 (CHEMBL4061982) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F Show InChI InChI=1S/C34H32F2N4O2/c35-27-17-7-3-13-23(27)31-37-29-19-9-5-15-25(29)33(41)39(31)21-11-1-2-12-22-40-32(24-14-4-8-18-28(24)36)38-30-20-10-6-16-26(30)34(40)42/h3-10,13-20,31-32,37-38H,1-2,11-12,21-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249987 (CHEMBL4082888) Show SMILES Cc1n(nc2c1c(C)nn(CCCN1CCC(CC1)N1C(Nc3ccccc3C1=O)c1ccccc1F)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C36H38FN7O2/c1-23-13-15-27(16-14-23)44-25(3)32-24(2)39-42(36(46)33(32)40-44)20-8-19-41-21-17-26(18-22-41)43-34(28-9-4-6-11-30(28)37)38-31-12-7-5-10-29(31)35(43)45/h4-7,9-16,26,34,38H,8,17-22H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256259 (CHEMBL4073926) Show SMILES Fc1ccc2NC(N(CCOc3ccc(cc3)-c3nc4ccccc4n3Cc3ccncc3)C(=O)c2c1)c1ccccc1F Show InChI InChI=1S/C35H27F2N5O2/c36-25-11-14-30-28(21-25)35(43)41(34(39-30)27-5-1-2-6-29(27)37)19-20-44-26-12-9-24(10-13-26)33-40-31-7-3-4-8-32(31)42(33)22-23-15-17-38-18-16-23/h1-18,21,34,39H,19-20,22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019850 (CHEMBL3286915) Show SMILES Cc1nc2ccccc2n1CCOC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C30H31N5O2/c1-22-31-25-11-5-7-13-27(25)34(22)19-20-37-29(36)24-15-17-33(18-16-24)30-32-26-12-6-8-14-28(26)35(30)21-23-9-3-2-4-10-23/h2-14,24H,15-21H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019852 (CHEMBL3286917) Show SMILES C(Cn1ccnc1-c1ccccc1)Oc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C31H26N4O/c1-3-9-24(10-4-1)23-35-29-14-8-7-13-28(29)33-31(35)26-15-17-27(18-16-26)36-22-21-34-20-19-32-30(34)25-11-5-2-6-12-25/h1-20H,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019843 (CHEMBL3286909) Show SMILES O=C(OC[C@H](C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1 |r| Show InChI InChI=1S/C38H40N6O2S/c45-37(30-16-21-42(22-17-30)38-41-31-10-4-6-12-33(31)43(38)24-27-18-23-47-26-27)46-25-35(28-14-19-39-20-15-28)44-34-13-7-5-11-32(34)40-36(44)29-8-2-1-3-9-29/h1-13,18,23,26,28,30,35,39H,14-17,19-22,24-25H2/t35-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019849 (CHEMBL3286914) Show SMILES O=C(OCCn1ccnc1-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C31H31N5O2/c37-30(38-22-21-34-20-17-32-29(34)25-11-5-2-6-12-25)26-15-18-35(19-16-26)31-33-27-13-7-8-14-28(27)36(31)23-24-9-3-1-4-10-24/h1-14,17,20,26H,15-16,18-19,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50542203 (CHEMBL4635027) Show SMILES Cc1n(nc2c1c(C)nn(CCCC(=O)NCCCCCCCCNc1ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c1)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C39H46N8O6/c1-24-12-15-28(16-13-24)47-26(3)34-25(2)43-45(39(53)35(34)44-47)22-10-11-32(48)41-21-9-7-5-4-6-8-20-40-27-14-17-29-30(23-27)38(52)46(37(29)51)31-18-19-33(49)42-36(31)50/h12-17,23,31,40H,4-11,18-22H2,1-3H3,(H,41,48)(H,42,49,50)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249989 (CHEMBL1387422) Show SMILES CC(CNC(=O)CCCn1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C27H31N5O2/c1-18-12-14-23(15-13-18)32-21(4)25-20(3)29-31(27(34)26(25)30-32)16-8-11-24(33)28-17-19(2)22-9-6-5-7-10-22/h5-7,9-10,12-15,19H,8,11,16-17H2,1-4H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249989 (CHEMBL1387422) Show SMILES CC(CNC(=O)CCCn1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C27H31N5O2/c1-18-12-14-23(15-13-18)32-21(4)25-20(3)29-31(27(34)26(25)30-32)16-8-11-24(33)28-17-19(2)22-9-6-5-7-10-22/h5-7,9-10,12-15,19H,8,11,16-17H2,1-4H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249990 (CHEMBL4090022) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F Show InChI InChI=1S/C33H30F2N4O2/c34-26-16-6-2-12-22(26)30-36-28-18-8-4-14-24(28)32(40)38(30)20-10-1-11-21-39-31(23-13-3-7-17-27(23)35)37-29-19-9-5-15-25(29)33(39)41/h2-9,12-19,30-31,36-37H,1,10-11,20-21H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019844 (CHEMBL3286910) Show SMILES CC(C)c1nc2ccccc2n1[C@H](COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1)C1CCNCC1 |r| Show InChI InChI=1S/C35H42N6O2S/c1-24(2)33-37-29-8-4-6-10-31(29)41(33)32(26-11-16-36-17-12-26)22-43-34(42)27-13-18-39(19-14-27)35-38-28-7-3-5-9-30(28)40(35)21-25-15-20-44-23-25/h3-10,15,20,23-24,26-27,32,36H,11-14,16-19,21-22H2,1-2H3/t32-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019846 (CHEMBL3286912) Show SMILES CCc1nc2ccccc2n1[C@H](COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1)C1CCNCC1 |r| Show InChI InChI=1S/C34H40N6O2S/c1-2-32-36-28-8-4-6-10-30(28)40(32)31(25-11-16-35-17-12-25)22-42-33(41)26-13-18-38(19-14-26)34-37-27-7-3-5-9-29(27)39(34)21-24-15-20-43-23-24/h3-10,15,20,23,25-26,31,35H,2,11-14,16-19,21-22H2,1H3/t31-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249980 (CHEMBL4091313) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F Show InChI InChI=1S/C35H34F2N4O2/c36-28-18-8-4-14-24(28)32-38-30-20-10-6-16-26(30)34(42)40(32)22-12-2-1-3-13-23-41-33(25-15-5-9-19-29(25)37)39-31-21-11-7-17-27(31)35(41)43/h4-11,14-21,32-33,38-39H,1-3,12-13,22-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50542198 (CHEMBL4647310) Show SMILES Cc1n(nc2c1c(C)nn(CCCC(=O)NCCCCCCCCNc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C39H46N8O6/c1-24-15-17-27(18-16-24)47-26(3)33-25(2)43-45(39(53)35(33)44-47)23-11-14-31(48)41-22-9-7-5-4-6-8-21-40-29-13-10-12-28-34(29)38(52)46(37(28)51)30-19-20-32(49)42-36(30)50/h10,12-13,15-18,30,40H,4-9,11,14,19-23H2,1-3H3,(H,41,48)(H,42,49,50)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256251 (CHEMBL4100698) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCOc1ccc(cc1)-c1nc2ccccc2n1Cc1ccncc1 Show InChI InChI=1S/C35H28FN5O2/c36-29-9-3-1-7-27(29)34-38-30-10-4-2-8-28(30)35(42)40(34)21-22-43-26-15-13-25(14-16-26)33-39-31-11-5-6-12-32(31)41(33)23-24-17-19-37-20-18-24/h1-20,34,38H,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019822 (CHEMBL3286902) Show SMILES O=C(OCC(C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1 Show InChI InChI=1S/C38H40N6O2S/c45-37(30-16-21-42(22-17-30)38-41-31-10-4-6-12-33(31)43(38)24-27-18-23-47-26-27)46-25-35(28-14-19-39-20-15-28)44-34-13-7-5-11-32(34)40-36(44)29-8-2-1-3-9-29/h1-13,18,23,26,28,30,35,39H,14-17,19-22,24-25H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256249 (CHEMBL4099759) Show SMILES Cc1ccc2NC(N(CCOc3ccc(cc3)-c3nc4ccccc4n3Cc3ccncc3)C(=O)c2c1)c1ccccc1F Show InChI InChI=1S/C36H30FN5O2/c1-24-10-15-31-29(22-24)36(43)41(35(39-31)28-6-2-3-7-30(28)37)20-21-44-27-13-11-26(12-14-27)34-40-32-8-4-5-9-33(32)42(34)23-25-16-18-38-19-17-25/h2-19,22,35,39H,20-21,23H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256247 (CHEMBL4077104) Show SMILES COc1ccc2C(=O)N(CCOc3ccc(cc3)-c3nc4ccccc4n3Cc3ccncc3)C(Nc2c1)c1ccccc1F Show InChI InChI=1S/C36H30FN5O3/c1-44-27-14-15-29-32(22-27)40-35(28-6-2-3-7-30(28)37)41(36(29)43)20-21-45-26-12-10-25(11-13-26)34-39-31-8-4-5-9-33(31)42(34)23-24-16-18-38-19-17-24/h2-19,22,35,40H,20-21,23H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249989 (CHEMBL1387422) Show SMILES CC(CNC(=O)CCCn1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C27H31N5O2/c1-18-12-14-23(15-13-18)32-21(4)25-20(3)29-31(27(34)26(25)30-32)16-8-11-24(33)28-17-19(2)22-9-6-5-7-10-22/h5-7,9-10,12-15,19H,8,11,16-17H2,1-4H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Binding affinity to PDEdelta (unknown origin)				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019865 (CHEMBL3286929) Show SMILES C(Oc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1)[C@H](C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1 |r| Show InChI InChI=1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31-13-5-2-6-14-31/h1-22,30,38,41H,23-28H2/t38-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Binding affinity to PDEdelta (unknown origin)				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50529751 (CHEMBL4472979 | US10913710, Compound 16) Show SMILES CNc1nccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)n1 Show InChI InChI=1S/C30H39ClN6O4S2/c1-32-30-34-19-16-26(35-30)22-36(20-24-14-17-33-18-15-24)42(38,39)28-10-12-29(13-11-28)43(40,41)37(27-4-2-3-5-27)21-23-6-8-25(31)9-7-23/h6-13,16,19,24,27,33H,2-5,14-15,17-18,20-22H2,1H3,(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Binding affinity to PDEdelta (unknown origin)				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019813 (CHEMBL3286897) Show SMILES O=C(OCC(C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C40H42N6O2/c47-39(32-21-25-44(26-22-32)40-43-33-15-7-9-17-35(33)45(40)27-29-11-3-1-4-12-29)48-28-37(30-19-23-41-24-20-30)46-36-18-10-8-16-34(36)42-38(46)31-13-5-2-6-14-31/h1-18,30,32,37,41H,19-28H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249982 (CHEMBL4092911) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CCN1CCC(CC1)N1C(Nc2ccccc2C1=O)c1ccccc1F Show InChI InChI=1S/C35H33F2N5O2/c36-28-13-5-1-9-24(28)32-38-30-15-7-3-11-26(30)34(43)41(32)22-21-40-19-17-23(18-20-40)42-33(25-10-2-6-14-29(25)37)39-31-16-8-4-12-27(31)35(42)44/h1-16,23,32-33,38-39H,17-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256250 (CHEMBL4102432) Show SMILES Fc1ccccc1C1Nc2ccc(Cl)cc2C(=O)N1CCOc1ccc(cc1)-c1nc2ccccc2n1Cc1ccncc1 Show InChI InChI=1S/C35H27ClFN5O2/c36-25-11-14-30-28(21-25)35(43)41(34(39-30)27-5-1-2-6-29(27)37)19-20-44-26-12-9-24(10-13-26)33-40-31-7-3-4-8-32(31)42(33)22-23-15-17-38-18-16-23/h1-18,21,34,39H,19-20,22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256248 (CHEMBL4087332) Show SMILES Fc1ccc2C(=O)N(CCOc3ccc(cc3)-c3nc4ccccc4n3Cc3ccncc3)C(Nc2c1)c1ccccc1F Show InChI InChI=1S/C35H27F2N5O2/c36-25-11-14-28-31(21-25)40-34(27-5-1-2-6-29(27)37)41(35(28)43)19-20-44-26-12-9-24(10-13-26)33-39-30-7-3-4-8-32(30)42(33)22-23-15-17-38-18-16-23/h1-18,21,34,40H,19-20,22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019845 (CHEMBL3286911) Show SMILES O=C(OC[C@H](C1CCNCC1)n1c(nc2ccccc12)C1CC1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1 |r| Show InChI InChI=1S/C35H40N6O2S/c42-34(27-13-18-39(19-14-27)35-38-28-5-1-3-7-30(28)40(35)21-24-15-20-44-23-24)43-22-32(25-11-16-36-17-12-25)41-31-8-4-2-6-29(31)37-33(41)26-9-10-26/h1-8,15,20,23,25-27,32,36H,9-14,16-19,21-22H2/t32-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019825 (CHEMBL3286905) Show SMILES O=C(OCC(C1CCNC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C39H40N6O2/c46-38(30-20-23-43(24-21-30)39-42-32-15-7-9-17-34(32)44(39)26-28-11-3-1-4-12-28)47-27-36(31-19-22-40-25-31)45-35-18-10-8-16-33(35)41-37(45)29-13-5-2-6-14-29/h1-18,30-31,36,40H,19-27H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50542199 (CHEMBL4641483) Show SMILES Cc1n(nc2c1c(C)nn(CCCC(=O)NCCCCCCCNc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c2=O)-c1ccc(C)cc1 Show InChI InChI=1S/C38H44N8O6/c1-23-14-16-26(17-15-23)46-25(3)32-24(2)42-44(38(52)34(32)43-46)22-10-13-30(47)40-21-8-6-4-5-7-20-39-28-12-9-11-27-33(28)37(51)45(36(27)50)29-18-19-31(48)41-35(29)49/h9,11-12,14-17,29,39H,4-8,10,13,18-22H2,1-3H3,(H,40,47)(H,41,48,49)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 63: 7892-7905 (2020) Article DOI: 10.1021/acs.jmedchem.0c00929 BindingDB Entry DOI: 10.7270/Q2RN3CFH
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019851 (CHEMBL3286916) Show SMILES O=C(OCCn1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C35H33N5O2/c41-34(42-24-23-39-31-17-9-7-15-29(31)36-33(39)27-13-5-2-6-14-27)28-19-21-38(22-20-28)35-37-30-16-8-10-18-32(30)40(35)25-26-11-3-1-4-12-26/h1-18,28H,19-25H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019826 (CHEMBL3286906) Show SMILES O=C(OCC(CC1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C41H44N6O2/c48-40(33-21-25-45(26-22-33)41-44-35-15-7-9-17-37(35)46(41)28-31-11-3-1-4-12-31)49-29-34(27-30-19-23-42-24-20-30)47-38-18-10-8-16-36(38)43-39(47)32-13-5-2-6-14-32/h1-18,30,33-34,42H,19-29H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019825 (CHEMBL3286905) Show SMILES O=C(OCC(C1CCNC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C39H40N6O2/c46-38(30-20-23-43(24-21-30)39-42-32-15-7-9-17-34(32)44(39)26-28-11-3-1-4-12-28)47-27-36(31-19-22-40-25-31)45-35-18-10-8-16-33(35)41-37(45)29-13-5-2-6-14-29/h1-18,30-31,36,40H,19-27H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50249991 (CHEMBL4069561) Show SMILES Fc1ccccc1C1Nc2ccccc2C(=O)N1CC1CCC(CN2C(Nc3ccccc3C2=O)c2ccccc2F)CC1 |(30.58,-33,;31.92,-32.24,;33.26,-33.01,;34.59,-32.25,;34.59,-30.7,;33.26,-29.93,;31.94,-30.7,;30.61,-29.92,;29.26,-30.69,;27.92,-29.91,;26.59,-30.69,;25.26,-29.91,;25.26,-28.37,;26.59,-27.6,;27.92,-28.36,;29.26,-27.58,;29.26,-26.04,;30.61,-28.36,;31.94,-27.6,;31.95,-26.06,;33.29,-25.3,;33.3,-23.76,;31.97,-22.99,;31.98,-21.45,;33.32,-20.68,;33.32,-19.15,;34.67,-18.4,;36,-19.17,;37.33,-18.43,;38.64,-19.2,;38.62,-20.74,;37.29,-21.49,;35.98,-20.71,;34.64,-21.47,;34.63,-23.01,;31.99,-18.38,;30.66,-19.14,;29.33,-18.37,;29.33,-16.82,;30.67,-16.06,;32,-16.84,;33.34,-16.07,;30.63,-23.75,;30.62,-25.29,)| Show InChI InChI=1S/C36H34F2N4O2/c37-29-13-5-1-9-25(29)33-39-31-15-7-3-11-27(31)35(43)41(33)21-23-17-19-24(20-18-23)22-42-34(26-10-2-6-14-30(26)38)40-32-16-8-4-12-28(32)36(42)44/h1-16,23-24,33-34,39-40H,17-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, Second Military Medical University , Shanghai 200433, China. Curated by ChEMBL					Assay Description Inhibition of Atrovastatin-PEG3-FITC binding to PDEdelta (unknown origin) incubated for 60 mins by fluorescence anisotropy assay				J Med Chem 60: 9400-9406 (2017) Article DOI: 10.1021/acs.jmedchem.7b01243 BindingDB Entry DOI: 10.7270/Q2571FDQ
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481674 (N1-(furan-2-ylmethyl)-N1-(3- methoxybenzyl)-N4- ((...) Show SMILES COc1cccc(CN(Cc2ccco2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)NCC2CCCO2)c1 Show InChI InChI=1S/C24H28N2O7S2/c1-31-20-6-2-5-19(15-20)17-26(18-22-8-4-14-33-22)35(29,30)24-11-9-23(10-12-24)34(27,28)25-16-21-7-3-13-32-21/h2,4-6,8-12,14-15,21,25H,3,7,13,16-18H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019823 (CHEMBL3286903) Show SMILES O=C(OCC(C1CCCCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1 Show InChI InChI=1S/C39H41N5O2S/c45-38(31-19-22-42(23-20-31)39-41-32-15-7-9-17-34(32)43(39)25-28-21-24-47-27-28)46-26-36(29-11-3-1-4-12-29)44-35-18-10-8-16-33(35)40-37(44)30-13-5-2-6-14-30/h2,5-10,13-18,21,24,27,29,31,36H,1,3-4,11-12,19-20,22-23,25-26H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481682 (N1-benzyl-N4-cyclopentyl-N1- (pyridin-2-ylmethyl)b...) Show SMILES O=S(=O)(NC1CCCC1)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)Cc1ccccn1 Show InChI InChI=1S/C24H27N3O4S2/c28-32(29,26-21-10-4-5-11-21)23-13-15-24(16-14-23)33(30,31)27(18-20-8-2-1-3-9-20)19-22-12-6-7-17-25-22/h1-3,6-9,12-17,21,26H,4-5,10-11,18-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481688 (N1-benzyl-N1-(2-chlorobenzyl)-N4- cyclopentylbenze...) Show SMILES Clc1ccccc1CN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)NC1CCCC1 Show InChI InChI=1S/C25H27ClN2O4S2/c26-25-13-7-4-10-21(25)19-28(18-20-8-2-1-3-9-20)34(31,32)24-16-14-23(15-17-24)33(29,30)27-22-11-5-6-12-22/h1-4,7-10,13-17,22,27H,5-6,11-12,18-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50256258 (CHEMBL4105186) Show SMILES Fc1ccccc1C1Nc2cc(Cl)ccc2C(=O)N1CCOc1ccc(cc1)-c1nc2ccccc2n1Cc1ccncc1 Show InChI InChI=1S/C35H27ClFN5O2/c36-25-11-14-28-31(21-25)40-34(27-5-1-2-6-29(27)37)41(35(28)43)19-20-44-26-12-9-24(10-13-26)33-39-30-7-3-4-8-32(30)42(33)22-23-15-17-38-18-16-23/h1-18,21,34,40H,19-20,22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
School of Pharmacy , Second Military Medical University , 325 Guohe Road , Shanghai 200433 , China. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 61: 2604-2610 (2018) Article DOI: 10.1021/acs.jmedchem.8b00057 BindingDB Entry DOI: 10.7270/Q2CZ39MM
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481608 (US10913710, Compound 23) Show SMILES Cc1ccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)cc1N Show InChI InChI=1S/C32H41ClN4O4S2/c1-24-6-7-27(20-32(24)34)22-36(21-26-16-18-35-19-17-26)42(38,39)30-12-14-31(15-13-30)43(40,41)37(29-4-2-3-5-29)23-25-8-10-28(33)11-9-25/h6-15,20,26,29,35H,2-5,16-19,21-23,34H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481611 (US10913710, Compound 26) Show SMILES Clc1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N(CC2CCCNC2)Cc2ccccc2)cc1 Show InChI InChI=1S/C31H38ClN3O4S2/c32-28-14-12-26(13-15-28)24-35(29-10-4-5-11-29)41(38,39)31-18-16-30(17-19-31)40(36,37)34(22-25-7-2-1-3-8-25)23-27-9-6-20-33-21-27/h1-3,7-8,12-19,27,29,33H,4-6,9-11,20-24H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM481652 (N1-benzyl-N4-(4-isopropylbenzyl)- N4-((tetrahydrof...) Show SMILES CC(C)c1ccc(CN(CC2CCCO2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)NCc2ccccc2)cc1 Show InChI InChI=1S/C28H34N2O5S2/c1-22(2)25-12-10-24(11-13-25)20-30(21-26-9-6-18-35-26)37(33,34)28-16-14-27(15-17-28)36(31,32)29-19-23-7-4-3-5-8-23/h3-5,7-8,10-17,22,26,29H,6,9,18-21H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V US Patent					Assay Description Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...				US Patent US10913710 (2021) BindingDB Entry DOI: 10.7270/Q2JW8HZB
					More data for this Ligand-Target Pair

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