252 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28248104	385	Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.	Friedrich-Alexander University Erlangen-N£Rnberg
28214075	30	Asymmetric total synthesis of tetrahydroprotoberberine derivatives and evaluation of their binding affinities at dopamine receptors.	Harvard Medical School
2527994	16	Conformational analysis and molecular modeling of 1-phenyl-, 4-phenyl-, and 1-benzyl-1,2,3,4-tetrahydroisoquinolines as D1 dopamine receptor ligands.	University of North Carolina
27688181	40	Synthesis and evaluation of C9 alkoxy analogues of (-)-stepholidine as dopamine receptor ligands.	City University of New York
27876250	60	Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH	Jagiellonian University Medical College
27839919	192	Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples.	University of Kansas
27564135	499	1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists.	Aptuit
27132867	154	Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists.	Friedrich-Alexander University
27080176	117	Synthesis and characterization of a series of chiral alkoxymethyl morpholine analogs as dopamine receptor 4 (D4R) antagonists.	Vanderbilt University
26988801	55	Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.	Jagiellonian University Medical College
27032890	52	Tetrahydroprotoberberine alkaloids with dopamine ands receptor affinity.	City University of New York
26786693	153	Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists.	Aptuit
26475518	19	Synthesis and evaluation of aporphine analogs containing C1 allyl isosteres at the h5-HT(2A) receptor.	City University of New York
26288260	34	Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library.	Universit Degli Studi Di Milano
26299826	112	1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation.	Friedrich-Alexander University
26227779	37	Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold.	Fudan University
25076379	87	Structural manipulation on the catecholic fragment of dopamine D(1) receptor agonist 1-phenyl-N-methyl-benzazepines.	Shanghai Institute of Materia Medica (Simm)
25564378	56	Fluoro-substituted phenylazocarboxamides: Dopaminergic behavior and N-arylating properties for irreversible binding.	Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
25695425	62	Semisynthetic Studies on and Biological Evaluation of N-Methyllaurotetanine Analogues as Ligands for 5-HT Receptors.	City University of New York
25734236	83	Molecular determinants of biased agonism at the dopamine D2 receptor.	Friedrich-Alexander University
25969169	54	A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.	University of Barcelona
25599836	14	Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity.	Boehringer Ingelheim (Canada)
25557493	109	Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.	Jagiellonian University Collegium Medicum
25070422	126	Further evaluation of the tropane analogs of haloperidol.	Florida A&M University
25308766	56	Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles.	Chinese Academy of Sciences
25241924	47	The design and implementation of a generic lipopeptide scanning platform to enable the identification of 'locally acting' agonists for the apelin receptor.	Novartis Institutes For Biomedical Research
25221667	66	Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity.	Vanderbilt University
24831693	116	Functionally selective dopamine D2, D3 receptor partial agonists.	Friedrich-Alexander University
24805037	380	Novel arylsulfonamide derivatives with 5-HT6/5-HT7 receptor antagonism targeting behavioral and psychological symptoms of dementia.	Adamed
24800940	146	Identification of a new selective dopamine D4 receptor ligand.	Florida A&M University
24900831	62	Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities.	State Key Laboratory of Drug Research
24559051	141	Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.	Intra-Cellular Therapies
23333208	24	Design and synthesis of D1 agonist/D2 antagonist for treatment of schizophrenia.	Sanofi Us
23332346	69	Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.	Chinese Academy of Sciences
24900647	8	Bodilisant-a novel fluorescent, highly affine histamine h3 receptor ligand.	Goethe University
19796944	38	Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif.	Universidad De Santiago De Compostela
18534847	37	Dopamine/serotonin receptor ligands. Part 17: a cross-target SAR approach: affinities of azecine-styled ligands for 5-HT(2A) versus D1 and D2 receptors.	Friedrich-Schiller-Universit£T Jena
22959245	175	As(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs).	The University of Sydney
21413808	170	Synopsis of some recent tactical application of bioisosteres in drug design.	Bristol-Myers Squibb Pharmaceutical Research and Development
21381769	56	Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.	Universite£
23134120	72	Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective¿ opioid receptor agonist.	University of Innsbruck
23009245	53	Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.	Sanford-Burnham Medical Research Institute
23018094	16	Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D3 receptor-selective full agonist ligand.	Purdue University
22846798	48	Chemoenzymatic synthesis and evaluation of 3-azabicyclo[3.2.0]heptane derivatives as dopaminergic ligands.	University of Tartu
22748706	52	Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: selective inhibitors of dopamine D1 receptor.	Shenyang Pharmaceutical University
22608762	25	Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors.	Shanghai Institute of Pharmaceutical Industry
22542010	31	Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition.	Amgen
22313227	78	Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.	National Institute of Mental Health
22537450	54	Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.	Gedeon Richter
21726069	98	Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.	University of Namur
21666830	82	Synthesis and Biological Evaluation of N-Fluoroalkyl and 2-Fluoroalkoxy Substituted Aporphines: Potential PET Ligands for Dopamine D(2) Receptors.	Harvard Medical School
21207959	69	Syntheses of 2-amino and 2-halothiazole derivatives as high-affinity metabotropic glutamate receptor subtype 5 ligands and potential radioligands for in vivo imaging.	National Institute of Mental Health
20875743	90	Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity rela	Pfizer
20931963	112	Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome.	Aska Pharmaceutical
20684563	176	Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.	H. Lundbeck
20041669	85	Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.	Chinese Academy of Sciences
19963380	38	Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine.	Hunter College and The Graduate Center of The City University of New York
19744859	90	Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities?	Friedrich-Schiller-Universit£T Jena
19559623	33	'Click' D(1) receptor agonists with a 5-HT(1A) receptor pharmacophore producing D(2) receptor activity.	Chinese Academy of Sciences
19091563	79	Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics.	Johann Wolfgang Goethe Universit£T
19331412	122	N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists.	National Institute On Drug Abuse-Intramural Research Program
18468904	48	High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand.	Purdue University
18361484	61	(Phenylpiperazinyl-butyl)oxindoles as selective 5-HT7 receptor antagonists.	Egis Pharmaceuticals
18313303	10	A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol.	University Centre For Pharmacy
17483457	58	A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.	Abbott Laboratories
18176998	45	Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.	Abbott Laboratories
17154515	40	trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist.	Purdue University
16480278	279	1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.	Organix
16451077	86	Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.	Pfizer
16420061	161	Dopamine/serotonin receptor ligands. 10: SAR Studies on azecine-type dopamine receptor ligands by functional screening at human cloned D1, D2L, and D5 receptors with a microplate reader based calcium assay lead to a novel potent D1/D5 selective antagonist.	University of Bonn
16198561	99	Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.	Novartis Institutes For Biomedical Research
16134944	85	Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists.	Friedrich-Alexander University
15357957	29	Synthesis, receptor binding and functional studies of mesoridazine stereoisomers.	Brigham & Women'S Hospital
14998318	112	Selective optimization of side activities: another way for drug discovery.	Prestwick Chemical
12361386	113	Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists.	Friedrich-Alexander University
11170639	73	Current and novel approaches to the drug treatment of schizophrenia.	Merck Sharp and Dohme Research Laboratories
11585444	295	From hit to lead. Analyzing structure-profile relationships.	Universities of Lille
9784114	32	CoMFA-based prediction of agonist affinities at recombinant D1 vs D2 dopamine receptors.	University of Texas At Austin
8632409	15	Comparative molecular field analysis-based prediction of drug affinities at recombinant D1A dopamine receptors.	Va Medical Center
7658429	31	(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431).	Abbott Laboratories
1531365	7	A study on the contribution of the 1-phenyl substituent to the molecular electrostatic potentials of some benzazepines in relation to selective dopamine D-1 receptor activity.	University of Lund
1531075	13	(+/-)-3-allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as selective high affinity D1 dopamine receptor antagonists: synthesis and structure-activity relationship.	Northeastern University
1684995	27	(+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship.	Northeastern University
1956042	39	Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands.	Research Biochemicals
1973733	17	Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series.	Royal Danish School of Pharmacy
1977907	33	(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.	Abbott Laboratories
3263503	3	A photoaffinity label for the D-1 dopamine receptor, (RS)-7-[125I]Iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5- tetrahydro-1H-3-benzazepine, selectively identifies the ligand binding subunits of the receptor.	Northeastern University
15203136	39	(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.	Virginia Commonwealth University
22284818	4	First enantioselective syntheses of the dopamine D1 and D2 receptor modulators, (+)- and (-)-govadine.	University of British Columbia
21888437	20	Chiral indolo[3,2-f][3]benzazecine-type dopamine receptor antagonists: synthesis and activity of racemic and enantiopure derivatives.	Martin-Luther-Universit£T Halle-Wittenberg
22204903	6	Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines.	Quimique C£A.
21899931	27	Synthesis and pharmacological evaluation of indole-based sigma receptor ligands.	The University of Mississippi
21862338	6	Assessment of dopamine D¿? receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393.	Purdue University
21788137	33	N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (s) receptor ligands.	The University of Sydney
21591752	41	Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.	Soochow University College of Pharmaceutical Sciences
21550699	24	New 2-thioether-substituted apomorphines as potent and selective dopamine D2 receptor agonists.	University of Tartu
21555222	25	Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (s) receptor ligands modulates off-target activity and subtype selectivity.	The University of Sydney
21334902	46	Further SAR study on 11-O-substituted aporphine analogues: identification of highly potent dopamine D3 receptor ligands.	Chinese Academy of Sciences
20949929	63	Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.	Bristol-Myers Squibb
20813948	63	Spiroindolones, a potent compound class for the treatment of malaria.	Swiss Tropical and Public Health Institute
20709559	16	Facile synthesis of octahydrobenzo[h]isoquinolines: novel and highly potent D1 dopamine agonists.	Purdue University
20620058	41	Smoothened antagonists for hair inhibition.	Pfizer
20591666	66	A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.	Università
20384344	42	Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.	Meiji Seika Kaisha
20180564	24	Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists.	Friedrich-Schiller-Universit£T Jena
20064718	88	Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists.	Merck Research Laboratories
20061148	73	Discovery of new SCH 39166 analogs as potent and selective dopamine D1 receptor antagonists.	Merck Research Laboratories
19646882	72	Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.	University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and The Informatics Institute of Umdnj
19643610	24	Design and discovery of 1,3-benzodiazepines as novel dopamine antagonists.	Schering-Plough Research Institute
19783143	65	Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: discovery, characterization and preliminary SAR of a promising lead.	Novartis Institutes For Biomedical Research
19454369	32	N-Substituted-2-alkyl- and 2-arylnorapomorphines: novel, highly active D2 agonists.	University of Tartu
8496700	16	The Role of Receptor Binding in Drug Discovery	TBA
	21	Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamides	TBA
	32	The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053)	TBA
19329329	183	Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET.	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz
18835172	19	Synthesis of 6-substituted 1-phenylbenzazepines and their dopamine D(1) receptor activities.	Chinese Academy of Sciences
18783955	35	N-Propylnoraporphin-11-O-yl carboxylic esters as potent dopamine D(2) and serotonin 5-HT(1A) receptor dual ligands.	Chinese Academy of Sciences
18774793	85	Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.	National Institute On Drug Abuses
18701276	97	Highly functionalized 7-azaindoles as selective PPAR gamma modulators.	Merck Research Laboratories
18595716	142	Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one.	Florida A&M University
18562201	13	Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphines.	Chinese Academy of Sciences
18053713	78	Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists.	Korea Research Institute of Chemical Technology
17976986	80	Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route.	Pfizer
17676831	67	Dopamine/serotonin receptor ligands. 16.(1) Expanding dibenz[d,g]azecines to 11- and 12-membered homologues. Interaction with dopamine D(1)-D(5) receptors.	Friedrich-Schiller-UniversitäT Jena
17571866	49	Synthesis and simple 18F-labeling of 3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a high affinity radioligand for imaging monkey brain metabotropic glutamate subtype-5 receptors with positron emission tomography.	National Institute of Mental Health
17539620	13	Novel ergopeptides as dual ligands for adenosine and dopamine receptors.	Institut D'Investigacions BiomèDiques August Pi I
17188870	36	Dopamine/serotonin receptor ligands. Part 15: Oxygenation of the benz-indolo-azecine LE 300 leads to novel subnanomolar dopamine D1/D5 antagonists.	Friedrich-Schiller-UniversitäT Jena
17034146	24	Dopamine/serotonin receptor ligands. 13: Homologization of a benzindoloazecine-type dopamine receptor antagonist modulates the affinities for dopamine D(1)-D(5) receptors.	Friedrich-Schiller-UniversitäT Jena
16809034	142	Hydrazides of clozapine: a new class of D1 dopamine receptor subtype selective antagonists.	Schering-Plough Research Institute
16806922	126	Modification of the clozapine structure by parallel synthesis.	Schering-Plough Research Institute
16759104	46	Fancy bioisosteres: novel paracyclophane derivatives as super-affinity dopamine D3 receptor antagonists.	Friedrich-Alexander University
16722655	28	Discovery of a novel, orally active, small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist.	Pfizer
16539400	97	Dopamine/serotonin receptor ligands. 12(1): SAR studies on hexahydro-dibenz[d,g]azecines lead to 4-chloro-7-methyl-5,6,7,8,9,14-hexahydrodibenz[d,g]azecin-3-ol, the first picomolar D5-selective dopamine-receptor antagonist.	Friedrich-Schiller-UniversitäT Jena
16392798	46	Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.	Columbia University College of Physicians and Surgeons
16271293	35	Synthesis and SAR of highly potent and selective dopamine D(3)-receptor antagonists: Quinolin(di)one and benzazepin(di)one derivatives. herve.geneste@abbott.com.	Abbott
16216506	31	3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective alpha(1)-adrenoceptor ligands.	Università
16143528	213	Synthesis of potent and selective serotonin 5-HT1B receptor ligands.	Columbia University College of Physicians and Surgeons
16134937	154	6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.	7Tm Pharma
15771415	155	Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.	Johnson & Johnson Pharmaceutical Research & Development
15293986	65	Dopamine/serotonin receptor ligands. 9. Oxygen-containing midsized heterocyclic ring systems and nonrigidized analogues. A step toward dopamine D5 receptor selectivity.	Friedrich-Schiller-UniversitäT Jena
15149647	10	Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.	Pfizer
14611858	65	1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands.	Neurogen
32107165	57	Identification of C10 nitrogen-containing aporphines with dopamine D	City University of New York
32631561	110	Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HT	City University of New York
32631525	36	Synthesis and dopamine receptor pharmacological evaluations on ring C ortho halogenated 1-phenylbenzazepines.	City University of New York
32227883	40	Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge	University of Mississippi
31098001	35	Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists.	University of Texas Medical Branch
32342685	325	Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D	National Institute of Neurological Disorders and Stroke
32282200	320	Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands.	Shanghaitech University
10464021	59	N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents.	Knoll Pharmaceuticals
31021617	136	Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D	University of Pennsylvania
30875219	254	Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D	University of North Carolina At Chapel Hill
10360732	45	trans-2,6-,3,6- and 4,6-diaza-5,6,6a,7,8,12b-hexahydro-benzo[c]phenanthrene-10,11- diols as dopamine agonists.	Abbott Laboratories
30525590	20	Novel Strategies To Activate the Dopamine D	Ucb Pharma
29939744	179	Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.	Shanghaitech University
9873609	15	NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.	Neurogen
31357129	61	Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs.	Medical University of Lublin
31185168	144	Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.	Rti International
31387791	60	Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D	Temple University
32184974	222	Structure-Functional-Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased Ligands.	Duke University
30981605	40	Chemical synthesis, microbial transformation and biological evaluation of tetrahydroprotoberberines as dopamine D1/D2 receptor ligands.	Huzhou University
31938453	10	Novel Pyrazolyl-dihydroisoquinolines as Positive Allosteric Modulator of the Dopamine D1 Receptor.	Arrival Discovery
31532644	8	Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1	Amri
31613617	195	Benzyl Phenylsemicarbazides: A Chemistry-Driven Approach Leading to G Protein-Biased Dopamine D	Friedrich-Alexander-Universit£T Erlangen-N£Rnberg
31620230	283	3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT	University of Minnesota Twin Cities
8709107	99	Dopamine D3 and D4 receptor antagonists: synthesis and structure--activity relationships of (S)-(+)-N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-4- [(cyclopropylcarbonyl) amino]-2-methoxybenzamide (YM-43611) and related compounds.	Yamanouchi Pharmaceutical
26565745	165	Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example.	Janssen Pharmaceutica
7909336	27	A new arylpiperazine antipsychotic with high D2/D3/5-HT1A/alpha 1A-adrenergic affinity and a low potential for extrapyramidal effects.	R. W. Johnson Pharmaceutical Research Institute
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