Found 1694 hits with Last Name = 'hu' and Initial = 'jw' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50454329
(CHEMBL2112647)Show SMILES [H][C@@]12CC(CO)=CC[C@@]1([H])C(C)(C)Oc1cc(CCCCCC(C)(C)C)ccc21 |c:5| Show InChI InChI=1S/C25H38O2/c1-24(2,3)14-8-6-7-9-18-10-12-20-21-15-19(17-26)11-13-22(21)25(4,5)27-23(20)16-18/h10-12,16,21-22,26H,6-9,13-15,17H2,1-5H3/t21-,22+/m0/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparation |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50330773
(((6aR,10aR)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a...)Show SMILES CCCCCCC(C)(C)c1ccc2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |r,c:17| Show InChI InChI=1S/C25H38O2/c1-6-7-8-9-14-24(2,3)19-11-12-20-21-15-18(17-26)10-13-22(21)25(4,5)27-23(20)16-19/h10-12,16,21-22,26H,6-9,13-15,17H2,1-5H3/t21-,22+/m0/s1 | PDB
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| Article
PubMed
| 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to CB2 receptor |
Bioorg Med Chem 18: 7809-15 (2010)
Article DOI: 10.1016/j.bmc.2010.09.061
BindingDB Entry DOI: 10.7270/Q2ZK5HP7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| PDB
Article
PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Binding affinity to human CB2 receptor by filtration assay |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| PDB
Article
PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to displace [3H]CP-55,940 from cloned human CB2 receptor |
Bioorg Med Chem Lett 15: 4110-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.008
BindingDB Entry DOI: 10.7270/Q2KD1XGV |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50071414
((6aR,10aR)-3-((1S,2R)-1,2-Dimethyl-heptyl)-6,6,9-t...)Show SMILES CCCCC[C@@H](C)[C@H](C)c1cc(O)c2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |c:17| Show InChI InChI=1S/C25H38O2/c1-7-8-9-10-17(3)18(4)19-14-22(26)24-20-13-16(2)11-12-21(20)25(5,6)27-23(24)15-19/h11,14-15,17-18,20-21,26H,7-10,12-13H2,1-6H3/t17-,18+,20-,21-/m1/s1 | PDB
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| 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940 |
Bioorg Med Chem Lett 8: 2223-6 (1999)
BindingDB Entry DOI: 10.7270/Q2KW5F78 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50071413
((6aR,10aR)-3-((1S,2R)-1,2-Dimethyl-heptyl)-9-hydro...)Show SMILES CCCCC[C@@H](C)[C@H](C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |c:18| Show InChI InChI=1S/C25H38O3/c1-6-7-8-9-16(2)17(3)19-13-22(27)24-20-12-18(15-26)10-11-21(20)25(4,5)28-23(24)14-19/h10,13-14,16-17,20-21,26-27H,6-9,11-12,15H2,1-5H3/t16-,17+,20-,21-/m1/s1 | PDB
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| 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940 |
Bioorg Med Chem Lett 8: 2223-6 (1999)
BindingDB Entry DOI: 10.7270/Q2KW5F78 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50053357
((6aR,10aR)-9-Hydroxymethyl-6,6-dimethyl-3-nonyl-6a...)Show SMILES CCCCCCCCCc1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |c:18| Show InChI InChI=1S/C25H38O3/c1-4-5-6-7-8-9-10-11-18-15-22(27)24-20-14-19(17-26)12-13-21(20)25(2,3)28-23(24)16-18/h12,15-16,20-21,26-27H,4-11,13-14,17H2,1-3H3/t20-,21-/m1/s1 | PDB
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PubMed
| 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparation |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50072775
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r| Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1 | PDB
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| PDB
Article
PubMed
| 0.580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membrane |
Bioorg Med Chem 16: 322-35 (2008)
Article DOI: 10.1016/j.bmc.2007.09.033
BindingDB Entry DOI: 10.7270/Q22V2H0T |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072775
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r| Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1 | PDB
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| PDB
Article
PubMed
| 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor |
Bioorg Med Chem 16: 322-35 (2008)
Article DOI: 10.1016/j.bmc.2007.09.033
BindingDB Entry DOI: 10.7270/Q22V2H0T |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50053357
((6aR,10aR)-9-Hydroxymethyl-6,6-dimethyl-3-nonyl-6a...)Show SMILES CCCCCCCCCc1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |c:18| Show InChI InChI=1S/C25H38O3/c1-4-5-6-7-8-9-10-11-18-15-22(27)24-20-14-19(17-26)12-13-21(20)25(2,3)28-23(24)16-18/h12,15-16,20-21,26-27H,4-11,13-14,17H2,1-3H3/t20-,21-/m1/s1 | PDB
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| Article
PubMed
| 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Compound was evaluated for Pharmacological response in the Cannabinoid receptor 1 |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50067499
((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)Show SMILES CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |r,c:18| Show InChI InChI=1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1 | PDB
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| 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity of the compound for the Cannabinoid receptor using [3H]- CP-55,940 as radioligand |
Bioorg Med Chem Lett 8: 2223-6 (1999)
BindingDB Entry DOI: 10.7270/Q2KW5F78 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50067735
((6aR,10aR)-3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl...)Show SMILES CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |c:17| Show InChI InChI=1S/C25H38O2/c1-7-8-9-10-13-24(3,4)18-15-21(26)23-19-14-17(2)11-12-20(19)25(5,6)27-22(23)16-18/h11,15-16,19-20,26H,7-10,12-14H2,1-6H3/t19-,20-/m1/s1 | PDB
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UniChem
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| PubMed
| 0.770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity of the compound for the cannabinoid brain receptor (CB1) using [3H]- CP-55,940 |
Bioorg Med Chem Lett 8: 2223-6 (1999)
BindingDB Entry DOI: 10.7270/Q2KW5F78 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50053359
((6aR,10aR)-6,6,9-Trimethyl-3-nonyl-6a,7,10,10a-tet...)Show SMILES CCCCCCCCCc1cc(O)c2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |c:17| Show InChI InChI=1S/C25H38O2/c1-5-6-7-8-9-10-11-12-19-16-22(26)24-20-15-18(2)13-14-21(20)25(3,4)27-23(24)17-19/h13,16-17,20-21,26H,5-12,14-15H2,1-4H3/t20-,21-/m1/s1 | PDB
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UniChem
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| Article
PubMed
| 0.770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Compound was evaluated for Pharmacological response in the Cannabinoid receptor 1 |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401063
(CHEMBL2206834)Show SMILES CCCCCn1cc(C(=O)c2ccc(Br)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H22BrNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50401063
(CHEMBL2206834)Show SMILES CCCCCn1cc(C(=O)c2ccc(Br)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H22BrNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50330773
(((6aR,10aR)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a...)Show SMILES CCCCCCC(C)(C)c1ccc2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |r,c:17| Show InChI InChI=1S/C25H38O2/c1-6-7-8-9-14-24(2,3)19-11-12-20-21-15-18(17-26)10-13-22(21)25(4,5)27-23(20)16-19/h10-12,16,21-22,26H,6-9,13-15,17H2,1-5H3/t21-,22+/m0/s1 | PDB
NCI pathway
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| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to CB1 receptor |
Bioorg Med Chem 18: 7809-15 (2010)
Article DOI: 10.1016/j.bmc.2010.09.061
BindingDB Entry DOI: 10.7270/Q2ZK5HP7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50454329
(CHEMBL2112647)Show SMILES [H][C@@]12CC(CO)=CC[C@@]1([H])C(C)(C)Oc1cc(CCCCCC(C)(C)C)ccc21 |c:5| Show InChI InChI=1S/C25H38O2/c1-24(2,3)14-8-6-7-9-18-10-12-20-21-15-19(17-26)11-13-22(21)25(4,5)27-23(20)16-18/h10-12,16,21-22,26H,6-9,13-15,17H2,1-5H3/t21-,22+/m0/s1 | PDB
Reactome pathway
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UniChem
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| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Ability to bind with Cannabinoid receptor 1 using [H]CP-55940 as radioligand in rat brain membranes |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401059
(CHEMBL2206838)Show InChI InChI=1S/C24H22INO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brain |
Bioorg Med Chem Lett 15: 4110-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.008
BindingDB Entry DOI: 10.7270/Q2KD1XGV |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Binding affinity to human CB1 receptor by filtration assay |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401058
(CHEMBL2206839)Show SMILES CCCCCn1c(C)c(C(=O)c2ccc(I)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H24INO/c1-3-4-9-16-27-17(2)24(21-12-7-8-13-23(21)27)25(28)20-14-15-22(26)19-11-6-5-10-18(19)20/h5-8,10-15H,3-4,9,16H2,1-2H3 | PDB
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| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50323910
(2-((1S,3R)-3-hydroxycyclohexyl)-5-(2-methyloctan-2...)Show SMILES CCCCCCC(C)(C)c1ccc([C@H]2CCC[C@@H](O)C2)c(O)c1 Show InChI InChI=1S/C21H34O2/c1-4-5-6-7-13-21(2,3)17-11-12-19(20(23)15-17)16-9-8-10-18(22)14-16/h11-12,15-16,18,22-23H,4-10,13-14H2,1-3H3/t16-,18+/m0/s1 | PDB
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| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membrane |
Bioorg Med Chem 16: 322-35 (2008)
Article DOI: 10.1016/j.bmc.2007.09.033
BindingDB Entry DOI: 10.7270/Q22V2H0T |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401070
(CHEMBL2206856)Show SMILES CCCCCn1c(C)c(C(=O)c2ccc(F)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H24FNO/c1-3-4-9-16-27-17(2)24(21-12-7-8-13-23(21)27)25(28)20-14-15-22(26)19-11-6-5-10-18(19)20/h5-8,10-15H,3-4,9,16H2,1-2H3 | PDB
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| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50084617
(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)Show SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(=O)(=O)CC(O)=O Show InChI InChI=1S/C27H31N5O5S/c1-18(28)31-12-10-25(11-13-31)37-24-8-6-23(7-9-24)32(38(35,36)17-26(33)34)16-19-2-3-20-4-5-21(27(29)30)15-22(20)14-19/h2-9,14-15,25,28H,10-13,16-17H2,1H3,(H3,29,30)(H,33,34) | PDB
MMDB
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| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human Coagulation factor Xa (fXa) |
J Med Chem 45: 1221-32 (2002)
BindingDB Entry DOI: 10.7270/Q2319V5W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401066
(CHEMBL2206860)Show SMILES CCCCCn1c(C)c(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H24ClNO/c1-3-4-9-16-27-17(2)24(21-12-7-8-13-23(21)27)25(28)20-14-15-22(26)19-11-6-5-10-18(19)20/h5-8,10-15H,3-4,9,16H2,1-2H3 | PDB
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| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50401067
(CHEMBL2206859)Show SMILES CCCCCn1cc(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H22ClNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50401059
(CHEMBL2206838)Show InChI InChI=1S/C24H22INO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401062
(CHEMBL2206835)Show SMILES CCCCCn1c(C)c(C(=O)c2ccc(Br)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H24BrNO/c1-3-4-9-16-27-17(2)24(21-12-7-8-13-23(21)27)25(28)20-14-15-22(26)19-11-6-5-10-18(19)20/h5-8,10-15H,3-4,9,16H2,1-2H3 | PDB
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| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401067
(CHEMBL2206859)Show SMILES CCCCCn1cc(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H22ClNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50454328
(CHEMBL2112646)Show SMILES [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(CCCCCC(C)(C)C)ccc21 |c:4| Show InChI InChI=1S/C25H38O/c1-18-11-14-22-21(16-18)20-13-12-19(17-23(20)26-25(22,5)6)10-8-7-9-15-24(2,3)4/h11-13,17,21-22H,7-10,14-16H2,1-6H3/t21-,22+/m0/s1 | PDB
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| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Ability to bind with Cannabinoid receptor 2 using [H]CP 55,940 as radioligand from cloned human receptor preparation |
J Med Chem 39: 3875-7 (1996)
Article DOI: 10.1021/jm960394y
BindingDB Entry DOI: 10.7270/Q2R49PVQ |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50287933
((6aR,10aR)-3-(1,1-Dimethyl-heptyl)-6,6,9-trimethyl...)Show SMILES CCCCCCC(C)(C)c1ccc2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |c:16| Show InChI InChI=1S/C25H38O/c1-7-8-9-10-15-24(3,4)19-12-13-20-21-16-18(2)11-14-22(21)25(5,6)26-23(20)17-19/h11-13,17,21-22H,7-10,14-16H2,1-6H3/t21-,22+/m0/s1 | PDB
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| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to CB2 receptor |
Bioorg Med Chem 18: 7809-15 (2010)
Article DOI: 10.1016/j.bmc.2010.09.061
BindingDB Entry DOI: 10.7270/Q2ZK5HP7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401071
(CHEMBL2206855)Show InChI InChI=1S/C24H22FNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
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| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401047
(CHEMBL2206850)Show InChI InChI=1S/C24H22INO/c1-2-3-6-15-26-16-20(18-11-4-5-14-22(18)26)24(27)19-12-7-9-17-10-8-13-21(25)23(17)19/h4-5,7-14,16H,2-3,6,15H2,1H3 | PDB
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| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192607
((5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)Show SMILES CCCCCn1cc(cc1-c1ccccc1F)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H24FNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 | PDB
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| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192589
((5-(2-ethylphenyl)-1-pentyl-1H-pyrrol-3-yl)(naphth...)Show SMILES CCCCCn1cc(cc1-c1ccccc1CC)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C28H29NO/c1-3-5-10-18-29-20-23(19-27(29)25-16-9-6-12-21(25)4-2)28(30)26-17-11-14-22-13-7-8-15-24(22)26/h6-9,11-17,19-20H,3-5,10,18H2,1-2H3 | PDB
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| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50180036
((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)Show SMILES CCCC(C)(C)c1ccc2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1 |r,c:13| Show InChI InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1 | PDB
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| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 18: 7809-15 (2010)
Article DOI: 10.1016/j.bmc.2010.09.061
BindingDB Entry DOI: 10.7270/Q2ZK5HP7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192595
(CHEMBL220180 | JWH-370 | naphthalen-1-yl(1-pentyl-...)Show SMILES CCCCCn1cc(cc1-c1ccccc1C)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H27NO/c1-3-4-9-17-28-19-22(18-26(28)23-14-7-5-11-20(23)2)27(29)25-16-10-13-21-12-6-8-15-24(21)25/h5-8,10-16,18-19H,3-4,9,17H2,1-2H3 | PDB
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| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192601
((5-(2-chlorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)Show SMILES CCCCCn1cc(cc1-c1ccccc1Cl)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H24ClNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 | PDB
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| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401051
(CHEMBL2206846)Show SMILES CCCCCn1cc(C(=O)c2cccc3cccc(Br)c23)c2ccccc12 Show InChI InChI=1S/C24H22BrNO/c1-2-3-6-15-26-16-20(18-11-4-5-14-22(18)26)24(27)19-12-7-9-17-10-8-13-21(25)23(17)19/h4-5,7-14,16H,2-3,6,15H2,1H3 | PDB
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| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50192595
(CHEMBL220180 | JWH-370 | naphthalen-1-yl(1-pentyl-...)Show SMILES CCCCCn1cc(cc1-c1ccccc1C)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H27NO/c1-3-4-9-17-28-19-22(18-26(28)23-14-7-5-11-20(23)2)27(29)25-16-10-13-21-12-6-8-15-24(21)25/h5-8,10-16,18-19H,3-4,9,17H2,1-2H3 | PDB
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| 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from CB1 receptor in rat brain |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192603
(CHEMBL385940 | JWH-145 | naphthalen-1-yl(1-pentyl-...)Show InChI InChI=1S/C26H25NO/c1-2-3-9-17-27-19-22(18-25(27)21-12-5-4-6-13-21)26(28)24-16-10-14-20-11-7-8-15-23(20)24/h4-8,10-16,18-19H,2-3,9,17H2,1H3 | PDB
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| 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50401061
(CHEMBL2206836)Show InChI InChI=1S/C22H18INO/c1-2-13-24-14-19(17-9-5-6-10-21(17)24)22(25)18-11-12-20(23)16-8-4-3-7-15(16)18/h3-12,14H,2,13H2,1H3 | PDB
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PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50170357
(2-(2-Chloro-phenyl)-1-(1-pentyl-1H-indol-3-yl)-eth...)Show InChI InChI=1S/C21H22ClNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3 | PDB
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| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to displace [3H]CP-55,940 from cloned human CB2 receptor |
Bioorg Med Chem Lett 15: 4110-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.008
BindingDB Entry DOI: 10.7270/Q2KD1XGV |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192588
((1-hexyl-5-phenyl-1H-pyrrol-3-yl)(naphthalen-1-yl)...)Show SMILES CCCCCCn1cc(cc1-c1ccccc1)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H27NO/c1-2-3-4-10-18-28-20-23(19-26(28)22-13-6-5-7-14-22)27(29)25-17-11-15-21-12-8-9-16-24(21)25/h5-9,11-17,19-20H,2-4,10,18H2,1H3 | PDB
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| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50401071
(CHEMBL2206855)Show InChI InChI=1S/C24H22FNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 | PDB
NCI pathway
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| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RTI International
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cells after 1 hr by liquid scintillation spectrophotometry |
Bioorg Med Chem 20: 2067-81 (2012)
Article DOI: 10.1016/j.bmc.2012.01.038
BindingDB Entry DOI: 10.7270/Q2PG1SW6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50192607
((5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)Show SMILES CCCCCn1cc(cc1-c1ccccc1F)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H24FNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 | PDB
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| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from CB1 receptor in rat brain |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50192601
((5-(2-chlorophenyl)-1-pentyl-1H-pyrrol-3-yl)(napht...)Show SMILES CCCCCn1cc(cc1-c1ccccc1Cl)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H24ClNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 | PDB
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| 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from CB1 receptor in rat brain |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50170357
(2-(2-Chloro-phenyl)-1-(1-pentyl-1H-indol-3-yl)-eth...)Show InChI InChI=1S/C21H22ClNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3 | PDB
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| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brain |
Bioorg Med Chem Lett 15: 4110-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.008
BindingDB Entry DOI: 10.7270/Q2KD1XGV |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50192610
(CHEMBL384897 | JWH-372 | naphthalen-1-yl(1-pentyl-...)Show SMILES CCCCCn1cc(cc1-c1ccccc1C(F)(F)F)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H24F3NO/c1-2-3-8-16-31-18-20(17-25(31)23-13-6-7-15-24(23)27(28,29)30)26(32)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 | PDB
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| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 16: 5432-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.051
BindingDB Entry DOI: 10.7270/Q2610ZXH |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50170337
(2-(2-Bromo-phenyl)-1-(1-pentyl-1H-indol-3-yl)-etha...)Show InChI InChI=1S/C21H22BrNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3 | PDB
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| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University
Curated by ChEMBL
| Assay Description
Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brain |
Bioorg Med Chem Lett 15: 4110-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.008
BindingDB Entry DOI: 10.7270/Q2KD1XGV |
More data for this
Ligand-Target Pair | |
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