Compile Data Set for Download or QSAR

Found 79 hits with Last Name = 'achanta' and Initial = 'pk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50483134 (CHEBI:64156 | Imetit) Show SMILES NC(=N)SCCc1c[nH]cn1 Show InChI InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517508 (CHEMBL4594107) Show SMILES CC(C)N1CCCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C26H39F3N4O2/c1-19(2)32-12-4-11-31(15-16-32)18-25(34)30-24-8-7-22(17-23(24)26(27,28)29)35-21-9-13-33(14-10-21)20-5-3-6-20/h7-8,17,19-21H,3-6,9-16,18H2,1-2H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517531 (CHEMBL4445638) Show SMILES Cl.Cl.O=C(CN1CCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O2/c25-21(16-23-12-1-2-13-23)22-17-6-8-19(9-7-17)26-20-10-14-24(15-11-20)18-4-3-5-18/h6-9,18,20H,1-5,10-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517534 (CHEMBL4476066) Show SMILES Cl.Cl.CCOC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C24H36N4O4/c1-2-31-24(30)28-16-14-26(15-17-28)18-23(29)25-19-6-8-21(9-7-19)32-22-10-12-27(13-11-22)20-4-3-5-20/h6-9,20,22H,2-5,10-18H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517529 (CHEMBL4587541) Show SMILES Cl.Cl.OCC1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3.2ClH/c26-16-19-5-2-12-25(19)15-22(27)23-17-6-8-20(9-7-17)28-21-10-13-24(14-11-21)18-3-1-4-18;;/h6-9,18-19,21,26H,1-5,10-16H2,(H,23,27);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517507 (CHEMBL4456037) Show SMILES FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCN(CC1)C1CCC1 Show InChI InChI=1S/C27H39F3N4O2/c28-27(29,30)24-18-23(36-22-10-14-34(15-11-22)21-6-2-7-21)8-9-25(24)31-26(35)19-32-12-3-13-33(17-16-32)20-4-1-5-20/h8-9,18,20-22H,1-7,10-17,19H2,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517523 (CHEMBL4518550) Show SMILES Cl.Cl.Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCC1 Show InChI InChI=1S/C22H33N3O2/c1-17-15-20(27-19-9-13-25(14-10-19)18-5-4-6-18)7-8-21(17)23-22(26)16-24-11-2-3-12-24/h7-8,15,18-19H,2-6,9-14,16H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517505 (CHEMBL4521909) Show SMILES C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1C |r| Show InChI InChI=1S/C23H35N3O2/c1-17-15-21(28-20-10-13-25(14-11-20)19-6-3-7-19)8-9-22(17)24-23(27)16-26-12-4-5-18(26)2/h8-9,15,18-20H,3-7,10-14,16H2,1-2H3,(H,24,27)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517521 (CHEMBL4574463) Show SMILES O=C(NCCN1CCCC1)c1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C23H35N3O2/c27-23(24-13-18-25-14-3-4-15-25)19-7-9-21(10-8-19)28-22-11-16-26(17-12-22)20-5-1-2-6-20/h7-10,20,22H,1-6,11-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517502 (CHEMBL4439392) Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(CN1CCCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C23H35N3O2/c27-23(18-25-14-3-1-2-4-15-25)24-19-8-10-21(11-9-19)28-22-12-16-26(17-13-22)20-6-5-7-20/h8-11,20,22H,1-7,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517522 (CHEMBL4534815) Show SMILES C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C22H33N3O2/c1-17-4-3-13-25(17)16-22(26)23-18-7-9-20(10-8-18)27-21-11-14-24(15-12-21)19-5-2-6-19/h7-10,17,19,21H,2-6,11-16H2,1H3,(H,23,26)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517540 (CHEMBL4452215) Show SMILES O=C(NCCN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3/c26-22(23-10-13-24-14-16-27-17-15-24)18-4-6-20(7-5-18)28-21-8-11-25(12-9-21)19-2-1-3-19/h4-7,19,21H,1-3,8-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517527 (CHEMBL4576724) Show SMILES O=C(NCCN1CCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(23-12-17-24-13-1-2-14-24)18-6-8-20(9-7-18)27-21-10-15-25(16-11-21)19-4-3-5-19/h6-9,19,21H,1-5,10-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517491 (CHEMBL4468778) Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(NCCN1CCCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C23H35N3O2/c27-23(24-13-18-25-14-2-1-3-15-25)19-7-9-21(10-8-19)28-22-11-16-26(17-12-22)20-5-4-6-20/h7-10,20,22H,1-6,11-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517506 (CHEMBL4476420) Show SMILES Cl.Cl.Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCCC1 Show InChI InChI=1S/C23H35N3O2/c1-18-16-21(28-20-10-14-26(15-11-20)19-6-5-7-19)8-9-22(18)24-23(27)17-25-12-3-2-4-13-25/h8-9,16,19-20H,2-7,10-15,17H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517532 (CHEMBL4450961) Show SMILES O=C(CN1CCCC1)Nc1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(17-24-13-3-4-14-24)23-18-7-9-20(10-8-18)27-21-11-15-25(16-12-21)19-5-1-2-6-19/h7-10,19,21H,1-6,11-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517528 (CHEMBL4476745) Show SMILES Cl.Cl.CC(C)N1CCC(CC1)Oc1ccc(NC(=O)CN2CCCCC2)cc1 Show InChI InChI=1S/C21H33N3O2/c1-17(2)24-14-10-20(11-15-24)26-19-8-6-18(7-9-19)22-21(25)16-23-12-4-3-5-13-23/h6-9,17,20H,3-5,10-16H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517494 (CHEMBL4561912) Show SMILES OCC1CN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CCO1 Show InChI InChI=1S/C22H33N3O4/c26-16-21-14-24(12-13-28-21)15-22(27)23-17-4-6-19(7-5-17)29-20-8-10-25(11-9-20)18-2-1-3-18/h4-7,18,20-21,26H,1-3,8-16H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517504 (CHEMBL4464101) Show SMILES Cl.Cl.O=C(CN1CCCCC1)Nc1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C23H35N3O2/c27-23(18-25-14-4-1-5-15-25)24-19-8-10-21(11-9-19)28-22-12-16-26(17-13-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517501 (CHEMBL4578297) Show SMILES Cl.Cl.O=C(CN1CCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(17-24-13-2-1-3-14-24)23-18-7-9-20(10-8-18)27-21-11-15-25(16-12-21)19-5-4-6-19/h7-10,19,21H,1-6,11-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517519 (CHEMBL4527873) Show SMILES CN(C(=O)CN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3/c1-23(22(26)17-24-13-15-27-16-14-24)18-5-7-20(8-6-18)28-21-9-11-25(12-10-21)19-3-2-4-19/h5-8,19,21H,2-4,9-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517509 (CHEMBL4515325) Show SMILES CC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C23H34N4O3/c1-18(28)26-15-13-25(14-16-26)17-23(29)24-19-5-7-21(8-6-19)30-22-9-11-27(12-10-22)20-3-2-4-20/h5-8,20,22H,2-4,9-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517499 (CHEMBL4465570) Show SMILES CN(C)CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H29N3O2/c1-21(2)14-19(23)20-15-6-8-17(9-7-15)24-18-10-12-22(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517511 (CHEMBL4439589) Show SMILES Cl.Cl.OC1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C22H33N3O3/c26-19-8-12-24(13-9-19)16-22(27)23-17-4-6-20(7-5-17)28-21-10-14-25(15-11-21)18-2-1-3-18/h4-7,18-19,21,26H,1-3,8-16H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517512 (CHEMBL4564463) Show SMILES Cl.Cl.CC(C)N1CCC(CC1)Oc1ccc(NC(=O)CN2CCOCC2)cc1 Show InChI InChI=1S/C20H31N3O3/c1-16(2)23-9-7-19(8-10-23)26-18-5-3-17(4-6-18)21-20(24)15-22-11-13-25-14-12-22/h3-6,16,19H,7-15H2,1-2H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517497 (CHEMBL4593911) Show SMILES Cl.Cl.O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O3/c25-21(16-23-12-14-26-15-13-23)22-17-4-6-19(7-5-17)27-20-8-10-24(11-9-20)18-2-1-3-18/h4-7,18,20H,1-3,8-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517524 (CHEMBL4520938) Show SMILES Cl.Cl.O=C(CN1CCS(=O)(=O)CC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O4S/c25-21(16-23-12-14-29(26,27)15-13-23)22-17-4-6-19(7-5-17)28-20-8-10-24(11-9-20)18-2-1-3-18/h4-7,18,20H,1-3,8-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517498 (CHEMBL4470829) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(cc1)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C22H35N3O2/c1-18(2)25-15-10-21(11-16-25)27-20-8-6-19(7-9-20)22(26)23-12-17-24-13-4-3-5-14-24/h6-9,18,21H,3-5,10-17H2,1-2H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517510 (CHEMBL4440461) Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(Cc1ccncc1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C22H27N3O2/c26-22(16-17-8-12-23-13-9-17)24-18-4-6-20(7-5-18)27-21-10-14-25(15-11-21)19-2-1-3-19/h4-9,12-13,19,21H,1-3,10-11,14-16H2,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50517497 (CHEMBL4593911) Show SMILES Cl.Cl.O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O3/c25-21(16-23-12-14-26-15-13-23)22-17-4-6-19(7-5-17)27-20-8-10-24(11-9-20)18-2-1-3-18/h4-7,18,20H,1-3,8-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from rat histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517530 (CHEMBL4545816) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(cc1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C21H33N3O2/c1-17(2)24-14-9-20(10-15-24)26-19-7-5-18(6-8-19)21(25)22-11-16-23-12-3-4-13-23/h5-8,17,20H,3-4,9-16H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517503 (CHEMBL4515283) Show SMILES Cl.Cl.FC1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCCC3)cc2)CC1 Show InChI InChI=1S/C23H34FN3O2/c24-18-9-13-26(14-10-18)17-23(28)25-19-5-7-21(8-6-19)29-22-11-15-27(16-12-22)20-3-1-2-4-20/h5-8,18,20,22H,1-4,9-17H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517520 (CHEMBL4441571) Show SMILES CCN(C(=O)CN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C23H35N3O3/c1-2-26(23(27)18-24-14-16-28-17-15-24)20-6-8-21(9-7-20)29-22-10-12-25(13-11-22)19-4-3-5-19/h6-9,19,22H,2-5,10-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517500 (CHEMBL4554857) Show SMILES CCN(CC)CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H33N3O2/c1-3-23(4-2)16-21(25)22-17-8-10-19(11-9-17)26-20-12-14-24(15-13-20)18-6-5-7-18/h8-11,18,20H,3-7,12-16H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517493 (CHEMBL4451851) Show SMILES FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCCC1 Show InChI InChI=1S/C23H32F3N3O2/c24-23(25,26)20-15-19(31-18-9-13-29(14-10-18)17-5-4-6-17)7-8-21(20)27-22(30)16-28-11-2-1-3-12-28/h7-8,15,17-18H,1-6,9-14,16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517536 (CHEMBL4451155) Show SMILES Fc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C21H30FN3O3/c22-19-14-18(28-17-6-8-25(9-7-17)16-2-1-3-16)4-5-20(19)23-21(26)15-24-10-12-27-13-11-24/h4-5,14,16-17H,1-3,6-13,15H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517535 (CHEMBL4551256) Show SMILES O=C(Cc1cccnc1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H27N3O2/c26-22(15-17-3-2-12-23-16-17)24-18-6-8-20(9-7-18)27-21-10-13-25(14-11-21)19-4-1-5-19/h2-3,6-9,12,16,19,21H,1,4-5,10-11,13-15H2,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517513 (CHEMBL4444723) Show SMILES Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C22H33N3O3/c1-17-15-20(28-19-7-9-25(10-8-19)18-3-2-4-18)5-6-21(17)23-22(26)16-24-11-13-27-14-12-24/h5-6,15,18-19H,2-4,7-14,16H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517492 (CHEMBL4543074) Show SMILES FC1(F)CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C22H31F2N3O2/c23-22(24)10-14-26(15-11-22)16-21(28)25-17-4-6-19(7-5-17)29-20-8-12-27(13-9-20)18-2-1-3-18/h4-7,18,20H,1-3,8-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517533 (CHEMBL4459101) Show SMILES Cl.Cl.FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCC1 Show InChI InChI=1S/C22H30F3N3O2/c23-22(24,25)19-14-18(30-17-8-12-28(13-9-17)16-4-3-5-16)6-7-20(19)26-21(29)15-27-10-1-2-11-27/h6-7,14,16-17H,1-5,8-13,15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517541 (CHEMBL4467347) Show SMILES O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C22H33N3O3/c26-22(17-24-13-15-27-16-14-24)23-18-5-7-20(8-6-18)28-21-9-11-25(12-10-21)19-3-1-2-4-19/h5-8,19,21H,1-4,9-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517537 (CHEMBL4563100) Show SMILES Fc1cc(NC(=O)CN2CCOCC2)ccc1OC1CCN(CC1)C1CCC1 Show InChI InChI=1S/C21H30FN3O3/c22-19-14-16(23-21(26)15-24-10-12-27-13-11-24)4-5-20(19)28-18-6-8-25(9-7-18)17-2-1-3-17/h4-5,14,17-18H,1-3,6-13,15H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517514 (CHEMBL4441165) Show SMILES FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C22H30F3N3O3/c23-22(24,25)19-14-18(31-17-6-8-28(9-7-17)16-2-1-3-16)4-5-20(19)26-21(29)15-27-10-12-30-13-11-27/h4-5,14,16-17H,1-3,6-13,15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517515 (CHEMBL4574703) Show SMILES COc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C22H33N3O4/c1-27-21-15-19(29-18-7-9-25(10-8-18)17-3-2-4-17)5-6-20(21)23-22(26)16-24-11-13-28-14-12-24/h5-6,15,17-18H,2-4,7-14,16H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517538 (CHEMBL4571200) Show SMILES Cl.Cl.C[C@@H]1CCCN1CCc1ccc(NC(=O)CN2CCOCC2)cc1 |r| Show InChI InChI=1S/C19H29N3O2.2ClH/c1-16-3-2-9-22(16)10-8-17-4-6-18(7-5-17)20-19(23)15-21-11-13-24-14-12-21;;/h4-7,16H,2-3,8-15H2,1H3,(H,20,23);2*1H/t16-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517517 (CHEMBL4578666) Show SMILES O=C(CN1CCOCC1)Nc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C17H25N3O2/c21-17(14-20-9-11-22-12-10-20)18-16-5-3-15(4-6-16)13-19-7-1-2-8-19/h3-6H,1-2,7-14H2,(H,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM234385 (2-Methoxy-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4b...) Show SMILES COc1ccc2n3c(-c4ccccc4S3(=O)=O)c(OCCN(C)C)c2c1 Show InChI InChI=1S/C19H20N2O4S/c1-20(2)10-11-25-19-15-12-13(24-3)8-9-16(15)21-18(19)14-6-4-5-7-17(14)26(21,22)23/h4-9,12H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	127	-40.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd					Assay Description Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...				J Enzyme Inhib Med Chem 26: 341-9 (2011) Article DOI: 10.3109/14756366.2010.510471 BindingDB Entry DOI: 10.7270/Q2WW7GHT
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517526 (CHEMBL4442372) Show SMILES O=C(CN1CCOCC1)Nc1cccc(OC2CCN(CC2)C2CCC2)c1 Show InChI InChI=1S/C21H31N3O3/c25-21(16-23-11-13-26-14-12-23)22-17-3-1-6-20(15-17)27-19-7-9-24(10-8-19)18-4-2-5-18/h1,3,6,15,18-19H,2,4-5,7-14,16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	212	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM234384 (2-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...) Show SMILES CN(C)CCOc1c2-c3ccccc3S(=O)(=O)n2c2ccc(Cl)cc12 Show InChI InChI=1S/C18H17ClN2O3S/c1-20(2)9-10-24-18-14-11-12(19)7-8-15(14)21-17(18)13-5-3-4-6-16(13)25(21,22)23/h3-8,11H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	464	-37.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd					Assay Description Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...				J Enzyme Inhib Med Chem 26: 341-9 (2011) Article DOI: 10.3109/14756366.2010.510471 BindingDB Entry DOI: 10.7270/Q2WW7GHT
					More data for this Ligand-Target Pair

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