Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM86054 (5'-IODORESINIFERATOXIN | I-RTX) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Curated by PDSP Ki Database | J Pharmacol Exp Ther 303: 1052-60 (2002) Article DOI: 10.1124/jpet.102.040394 BindingDB Entry DOI: 10.7270/Q279437S | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM86054 (5'-IODORESINIFERATOXIN | I-RTX) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Curated by PDSP Ki Database | J Pharmacol Exp Ther 303: 1052-60 (2002) Article DOI: 10.1124/jpet.102.040394 BindingDB Entry DOI: 10.7270/Q279437S | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424254 (CHEMBL2314162) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Un-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 55 | -41.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424250 (CHEMBL2314153) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Un-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238299 (1-(3-azidophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 64 | -41.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193743 (Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193747 (Methyl 2-((3-(5-phenyl-3,4-bis((5-sulfamoyl-1,3,4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424245 (CHEMBL2314158) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424253 (CHEMBL2314161) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 108 | -39.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424247 (CHEMBL2314156) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 111 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424249 (CHEMBL2314154) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193738 (1-(3-(2-(1,3-Dioxo-1-phenylbutan-2-ylidene)hydrazi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 119 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193738 (1-(3-(2-(1,3-Dioxo-1-phenylbutan-2-ylidene)hydrazi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 119 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424249 (CHEMBL2314154) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424251 (CHEMBL2314152) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 128 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238299 (1-(3-azidophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 129 | -39.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424246 (CHEMBL2314157) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424253 (CHEMBL2314161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193744 (tert-Butyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193745 (1-(3-((2-Hydroxy-6-oxocyclohex-1-en-1-yl)diazenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 157 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424250 (CHEMBL2314153) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 159 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238300 (4-benzoyl-1-(3-((2-hydroxy-4-oxopent-2-en-3-yl) di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 160 | -38.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238302 (4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 166 | -38.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424248 (CHEMBL2314155) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 197 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193742 (Diethyl 2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl-1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193739 (Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 208 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238301 (4-benzoyl-1-(3-nitrophenyl)-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 215 | -38.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424251 (CHEMBL2314152) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193743 (Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 246 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424252 (CHEMBL2314151) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193746 (1-(3-((2-Hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424254 (CHEMBL2314162) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 318 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193747 (Methyl 2-((3-(5-phenyl-3,4-bis((5-sulfamoyl-1,3,4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 318 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238301 (4-benzoyl-1-(3-nitrophenyl)-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 337 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424244 (CHEMBL2314159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 349 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50424243 (CHEMBL2314160) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 379 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424245 (CHEMBL2314158) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 384 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193736 (1-(3-((2-Hydroxynaphthalen-1-yl)diazenyl)phenyl)-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 411 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193741 (Ethyl 3-oxo-3-phenyl-2-(2-(3-(5-phenyl-3,4-bis((5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 435 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424252 (CHEMBL2314151) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 448 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193742 (Diethyl 2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl-1,3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 461 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424247 (CHEMBL2314156) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 485 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193741 (Ethyl 3-oxo-3-phenyl-2-(2-(3-(5-phenyl-3,4-bis((5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 487 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50424246 (CHEMBL2314157) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University Curated by ChEMBL | Assay Description Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 21-7 (2012) Article DOI: 10.1016/j.bmc.2012.11.012 BindingDB Entry DOI: 10.7270/Q2NV9KJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM193737 (1-(3-(2-(2,4-Dioxopentan-3-ylidene)hydrazinyl)phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 494 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193745 (1-(3-((2-Hydroxy-6-oxocyclohex-1-en-1-yl)diazenyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 508 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238302 (4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 521 | -35.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM193744 (tert-Butyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulf...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 522 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229... | Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC | |||||||||||
More data for this Ligand-Target Pair |
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