Compile Data Set for Download or QSAR

Found 97 hits with Last Name = 'ballatore' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026750 (CHEMBL3354618) Show SMILES Cc1cccc(C)c1C1=C(O)CC(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1=O |c:9| Show InChI InChI=1S/C30H30ClNO4S/c1-18-5-3-6-19(2)28(18)29-27(33)17-22(30(29)34)15-20-7-4-8-21-16-24(11-14-26(20)21)32-37(35,36)25-12-9-23(31)10-13-25/h3-10,12-13,22,24,32-33H,11,14-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0150	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026748 (CHEMBL3354616) Show SMILES COc1ccc(cc1)C1=C(O)CC(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1=O |c:9| Show InChI InChI=1S/C29H28ClNO5S/c1-36-24-10-5-18(6-11-24)28-27(32)17-21(29(28)33)15-19-3-2-4-20-16-23(9-14-26(19)20)31-37(34,35)25-12-7-22(30)8-13-25/h2-8,10-13,21,23,31-32H,9,14-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0520	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50058027 (CHEMBL29374) Show SMILES OC(=O)CCc1cccc2CC(CCc12)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClNO4S/c20-15-5-8-17(9-6-15)26(24,25)21-16-7-10-18-13(4-11-19(22)23)2-1-3-14(18)12-16/h1-3,5-6,8-9,16,21H,4,7,10-12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assay				Bioorg Med Chem Lett 24: 4171-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.047 BindingDB Entry DOI: 10.7270/Q2QF8VJ5
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353639 (CHEMBL1829806) Show SMILES CC1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C21H22ClNO4S/c1-14-20(24)13-17(21(14)25)12-16-4-2-3-15(11-16)9-10-23-28(26,27)19-7-5-18(22)6-8-19/h2-8,11,14,17,23H,9-10,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026760 (CHEMBL3354614) Show SMILES OC1=C(C(=O)C(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1)c1ccccc1 |t:1| Show InChI InChI=1S/C28H26ClNO4S/c29-22-9-12-24(13-10-22)35(33,34)30-23-11-14-25-19(7-4-8-20(25)16-23)15-21-17-26(31)27(28(21)32)18-5-2-1-3-6-18/h1-10,12-13,21,23,30-31H,11,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353632 (CHEMBL1829812) Show SMILES OC1CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C(=O)C1CC1CC1 Show InChI InChI=1S/C24H28ClNO4S/c25-20-6-8-21(9-7-20)31(29,30)26-11-10-16-2-1-3-18(12-16)13-19-15-23(27)22(24(19)28)14-17-4-5-17/h1-3,6-9,12,17,19,22-23,26-27H,4-5,10-11,13-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026761 (CHEMBL3354615) Show SMILES OC1=C(C(=O)C(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1)c1ccc(F)cc1 |t:1| Show InChI InChI=1S/C28H25ClFNO4S/c29-21-6-11-24(12-7-21)36(34,35)31-23-10-13-25-18(2-1-3-19(25)15-23)14-20-16-26(32)27(28(20)33)17-4-8-22(30)9-5-17/h1-9,11-12,20,23,31-32H,10,13-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353635 (CHEMBL1829801) Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CCc2nnn[nH]2)c1 Show InChI InChI=1S/C17H18ClN5O2S/c18-15-5-7-16(8-6-15)26(24,25)19-11-10-14-3-1-2-13(12-14)4-9-17-20-22-23-21-17/h1-3,5-8,12,19H,4,9-11H2,(H,20,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353643 (CHEMBL1829808) Show SMILES CCC1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C22H24ClNO4S/c1-2-20-21(25)14-17(22(20)26)13-16-5-3-4-15(12-16)10-11-24-29(27,28)19-8-6-18(23)7-9-19/h3-9,12,17,20,24H,2,10-11,13-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026758 (CHEMBL3335473) Show SMILES OC(=O)Cc1cccc2CC(CCc12)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H18ClNO4S/c19-14-4-7-16(8-5-14)25(23,24)20-15-6-9-17-12(10-15)2-1-3-13(17)11-18(21)22/h1-5,7-8,15,20H,6,9-11H2,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026759 (CHEMBL3354613) Show SMILES CC1=C(O)CC(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1=O |c:1| Show InChI InChI=1S/C23H24ClNO4S/c1-14-22(26)13-17(23(14)27)11-15-3-2-4-16-12-19(7-10-21(15)16)25-30(28,29)20-8-5-18(24)6-9-20/h2-6,8-9,17,19,25-26H,7,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026753 (S-18886 | Terutroban) Show SMILES Cc1ccc2C[C@@H](CCc2c1CCC(O)=O)NS(=O)(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C20H22ClNO4S/c1-13-2-3-14-12-16(6-9-19(14)18(13)10-11-20(23)24)22-27(25,26)17-7-4-15(21)5-8-17/h2-5,7-8,16,22H,6,9-12H2,1H3,(H,23,24)/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353645 (CHEMBL1829810) Show SMILES CC(C)C1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C23H26ClNO4S/c1-15(2)22-21(26)14-18(23(22)27)13-17-5-3-4-16(12-17)10-11-25-30(28,29)20-8-6-19(24)7-9-20/h3-9,12,15,18,22,25H,10-11,13-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353640 (CHEMBL65121) Show SMILES OC(=O)CCc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C17H18ClNO4S/c18-15-5-7-16(8-6-15)24(22,23)19-11-10-14-3-1-2-13(12-14)4-9-17(20)21/h1-3,5-8,12,19H,4,9-11H2,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026751 (CHEMBL3354619) Show SMILES OC1=C(Cc2ccccc2)C(=O)C(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1 |c:1| Show InChI InChI=1S/C29H28ClNO4S/c30-23-9-12-25(13-10-23)36(34,35)31-24-11-14-26-20(7-4-8-21(26)17-24)16-22-18-28(32)27(29(22)33)15-19-5-2-1-3-6-19/h1-10,12-13,22,24,31-32H,11,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353632 (CHEMBL1829812) Show SMILES OC1CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C(=O)C1CC1CC1 Show InChI InChI=1S/C24H28ClNO4S/c25-20-6-8-21(9-7-20)31(29,30)26-11-10-16-2-1-3-18(12-16)13-19-15-23(27)22(24(19)28)14-17-4-5-17/h1-3,6-9,12,17,19,22-23,26-27H,4-5,10-11,13-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50193130 (CHEMBL3908209) Show SMILES CCOC(=O)c1cnc2ccc(F)cc2c1N1CCN(CC1)c1cc(C)nc2ncnn12 Show InChI InChI=1S/C22H22FN7O2/c1-3-32-21(31)17-12-24-18-5-4-15(23)11-16(18)20(17)29-8-6-28(7-9-29)19-10-14(2)27-22-25-13-26-30(19)22/h4-5,10-13H,3,6-9H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE by Ellman's method				Eur J Med Chem 165: 332-346 (2019) Article DOI: 10.1016/j.ejmech.2019.01.027 BindingDB Entry DOI: 10.7270/Q2988BJH
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353638 (CHEMBL1829805) Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CC2CC(=O)CC2=O)c1 Show InChI InChI=1S/C20H20ClNO4S/c21-17-4-6-19(7-5-17)27(25,26)22-9-8-14-2-1-3-15(10-14)11-16-12-18(23)13-20(16)24/h1-7,10,16,22H,8-9,11-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50058026 (CHEMBL3326602) Show SMILES OC1=C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)CCC1=O |c:1| Show InChI InChI=1S/C20H20ClNO4S/c21-17-5-7-18(8-6-17)27(25,26)22-11-10-14-2-1-3-15(12-14)13-16-4-9-19(23)20(16)24/h1-3,5-8,12,22,24H,4,9-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assay				Bioorg Med Chem Lett 24: 4171-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.047 BindingDB Entry DOI: 10.7270/Q2QF8VJ5
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026755 (CHEMBL3335482) Show SMILES OC1=C(C(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1)c1ccccc1 |t:1| Show InChI InChI=1S/C26H24ClNO4S/c27-22-9-11-23(12-10-22)33(31,32)28-14-13-18-5-4-6-19(15-18)16-21-17-24(29)25(26(21)30)20-7-2-1-3-8-20/h1-12,15,21,28-29H,13-14,16-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353640 (CHEMBL65121) Show SMILES OC(=O)CCc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C17H18ClNO4S/c18-15-5-7-16(8-6-15)24(22,23)19-11-10-14-3-1-2-13(12-14)4-9-17(20)21/h1-3,5-8,12,19H,4,9-11H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353635 (CHEMBL1829801) Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CCc2nnn[nH]2)c1 Show InChI InChI=1S/C17H18ClN5O2S/c18-15-5-7-16(8-6-15)26(24,25)19-11-10-14-3-1-2-13(12-14)4-9-17-20-22-23-21-17/h1-3,5-8,12,19H,4,9-11H2,(H,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353636 (CHEMBL1829802) Show SMILES Oc1c(NCc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)c(=O)c1=O Show InChI InChI=1S/C19H17ClN2O5S/c20-14-4-6-15(7-5-14)28(26,27)22-9-8-12-2-1-3-13(10-12)11-21-16-17(23)19(25)18(16)24/h1-7,10,21-23H,8-9,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353639 (CHEMBL1829806) Show SMILES CC1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C21H22ClNO4S/c1-14-20(24)13-17(21(14)25)12-16-4-2-3-15(11-16)9-10-23-28(26,27)19-7-5-18(22)6-8-19/h2-8,11,14,17,23H,9-10,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353643 (CHEMBL1829808) Show SMILES CCC1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C22H24ClNO4S/c1-2-20-21(25)14-17(22(20)26)13-16-5-3-4-15(12-16)10-11-24-29(27,28)19-8-6-18(23)7-9-19/h3-9,12,17,20,24H,2,10-11,13-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353640 (CHEMBL65121) Show SMILES OC(=O)CCc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C17H18ClNO4S/c18-15-5-7-16(8-6-15)24(22,23)19-11-10-14-3-1-2-13(12-14)4-9-17(20)21/h1-3,5-8,12,19H,4,9-11H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assay				Bioorg Med Chem Lett 24: 4171-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.047 BindingDB Entry DOI: 10.7270/Q2QF8VJ5
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353645 (CHEMBL1829810) Show SMILES CC(C)C1C(=O)CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O Show InChI InChI=1S/C23H26ClNO4S/c1-15(2)22-21(26)14-18(23(22)27)13-17-5-3-4-16(12-17)10-11-25-30(28,29)20-8-6-19(24)7-9-20/h3-9,12,15,18,22,25H,10-11,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353638 (CHEMBL1829805) Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CC2CC(=O)CC2=O)c1 Show InChI InChI=1S/C20H20ClNO4S/c21-17-4-6-19(7-5-17)27(25,26)22-9-8-14-2-1-3-15(10-14)11-16-12-18(23)13-20(16)24/h1-7,10,16,22H,8-9,11-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353646 (CHEMBL1829811) Show SMILES CC(C)COC1=C(C(C)C)C(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1 |c:5| Show InChI InChI=1S/C27H34ClNO4S/c1-18(2)17-33-25-16-22(27(30)26(25)19(3)4)15-21-7-5-6-20(14-21)12-13-29-34(31,32)24-10-8-23(28)9-11-24/h5-11,14,18-19,22,29H,12-13,15-17H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353636 (CHEMBL1829802) Show SMILES Oc1c(NCc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)c(=O)c1=O Show InChI InChI=1S/C19H17ClN2O5S/c20-14-4-6-15(7-5-14)28(26,27)22-9-8-12-2-1-3-13(10-12)11-21-16-17(23)19(25)18(16)24/h1-7,10,21-23H,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353644 (CHEMBL1829809) Show SMILES CCC1=C(CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O)OCC(C)C |t:2| Show InChI InChI=1S/C26H32ClNO4S/c1-4-24-25(32-17-18(2)3)16-21(26(24)29)15-20-7-5-6-19(14-20)12-13-28-33(30,31)23-10-8-22(27)9-11-23/h5-11,14,18,21,28H,4,12-13,15-17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	463	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353640 (CHEMBL65121) Show SMILES OC(=O)CCc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C17H18ClNO4S/c18-15-5-7-16(8-6-15)24(22,23)19-11-10-14-3-1-2-13(12-14)4-9-17(20)21/h1-3,5-8,12,19H,4,9-11H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	523	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX in RBL1 cells assessed as reduction in PGE2/D2 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs...				ACS Med Chem Lett 8: 864-868 (2017) Article DOI: 10.1021/acsmedchemlett.7b00212 BindingDB Entry DOI: 10.7270/Q2N87DD8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026754 (CHEMBL3335481) Show SMILES Cc1cccc(C)c1C1=C(O)CC(Cc2cccc3CCCCc23)C1=O |c:9| Show InChI InChI=1S/C24H26O2/c1-15-7-5-8-16(2)22(15)23-21(25)14-19(24(23)26)13-18-11-6-10-17-9-3-4-12-20(17)18/h5-8,10-11,19,25H,3-4,9,12-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	891	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026757 (CHEMBL3335483) Show SMILES OC1=C(C2CCCCC2)C(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1 |c:1| Show InChI InChI=1S/C26H30ClNO4S/c27-22-9-11-23(12-10-22)33(31,32)28-14-13-18-5-4-6-19(15-18)16-21-17-24(29)25(26(21)30)20-7-2-1-3-8-20/h4-6,9-12,15,20-21,28-29H,1-3,7-8,13-14,16-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	892	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501720 (CHEMBL4100090) Show SMILES Clc1ncn(c1-c1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H10Cl2N2/c16-12-6-8-13(9-7-12)19-10-18-15(17)14(19)11-4-2-1-3-5-11/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50058025 (CHEMBL3326603) Show SMILES OC1=CC(CC1=O)c1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 |t:1| Show InChI InChI=1S/C19H18ClNO4S/c20-16-4-6-17(7-5-16)26(24,25)21-9-8-13-2-1-3-14(10-13)15-11-18(22)19(23)12-15/h1-7,10-11,15,21-22H,8-9,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human TP receptor expressed in QBI-HEK 293A cells assessed as IP3 metabolite level after 1 hr by HTRF assay				Bioorg Med Chem Lett 24: 4171-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.047 BindingDB Entry DOI: 10.7270/Q2QF8VJ5
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353641 (CHEMBL1829804) Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCc1cccc(CCC2C(=O)CCC2=O)c1 Show InChI InChI=1S/C21H22ClNO4S/c22-17-5-7-18(8-6-17)28(26,27)23-13-12-16-3-1-2-15(14-16)4-9-19-20(24)10-11-21(19)25/h1-3,5-8,14,19,23H,4,9-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353634 (CHEMBL1828642) Show SMILES OCCCc1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C17H20ClNO3S/c18-16-6-8-17(9-7-16)23(21,22)19-11-10-15-4-1-3-14(13-15)5-2-12-20/h1,3-4,6-9,13,19-20H,2,5,10-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353642 (CHEMBL1829807) Show SMILES CC(C)COC1=C(C)C(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1 |c:5| Show InChI InChI=1S/C25H30ClNO4S/c1-17(2)16-31-24-15-21(25(28)18(24)3)14-20-6-4-5-19(13-20)11-12-27-32(29,30)23-9-7-22(26)8-10-23/h4-10,13,17,21,27H,11-12,14-16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501719 (CHEMBL4096719) Show SMILES Cc1cc(F)c(-c2c(Cl)ncn2-c2ccc(Cl)cc2)c(F)c1 |(15.62,-14.23,;14.16,-14.72,;13,-13.69,;11.54,-14.18,;10.39,-13.16,;11.24,-15.68,;9.78,-16.17,;9.3,-17.64,;10.21,-18.89,;7.79,-17.65,;7.29,-16.19,;8.53,-15.27,;8.51,-13.73,;9.84,-12.96,;9.83,-11.42,;8.49,-10.66,;8.48,-9.12,;7.16,-11.44,;7.18,-12.98,;12.39,-16.71,;12.07,-18.22,;13.85,-16.23,)| Show InChI InChI=1S/C16H10Cl2F2N2/c1-9-6-12(19)14(13(20)7-9)15-16(18)21-8-22(15)11-4-2-10(17)3-5-11/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501717 (CHEMBL4066021) Show SMILES Fc1ccc(F)c(c1)-c1cnc(Cl)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H8Cl2F2N2/c16-9-1-4-11(5-2-9)21-14(8-20-15(21)17)12-7-10(18)3-6-13(12)19/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501714 (CHEMBL4078728) Show SMILES Fc1ccc(Cl)c(F)c1-c1c(Cl)ncn1-c1ccc(Cl)cc1 |(12.16,-14.89,;12.47,-13.38,;13.93,-12.9,;14.25,-11.39,;13.09,-10.36,;13.39,-8.85,;11.63,-10.85,;10.48,-9.83,;11.33,-12.35,;9.86,-12.84,;9.39,-14.31,;10.3,-15.56,;7.87,-14.32,;7.38,-12.86,;8.61,-11.94,;8.6,-10.4,;9.93,-9.63,;9.92,-8.09,;8.58,-7.33,;8.56,-5.79,;7.24,-8.12,;7.26,-9.65,)| Show InChI InChI=1S/C15H7Cl3F2N2/c16-8-1-3-9(4-2-8)22-7-21-15(18)14(22)12-11(19)6-5-10(17)13(12)20/h1-7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501718 (CHEMBL4075689) Show SMILES Fc1cccc(F)c1-c1c(Cl)ncn1-c1ccc(Cl)cc1 |(14.61,-12.02,;15.76,-13.04,;17.22,-12.55,;18.38,-13.57,;18.06,-15.08,;16.6,-15.57,;16.29,-17.07,;15.45,-14.54,;13.99,-15.02,;13.52,-16.5,;14.43,-17.74,;12,-16.5,;11.51,-15.04,;12.74,-14.13,;12.73,-12.59,;14.06,-11.81,;14.05,-10.27,;12.71,-9.51,;12.69,-7.97,;11.37,-10.3,;11.39,-11.84,)| Show InChI InChI=1S/C15H8Cl2F2N2/c16-9-4-6-10(7-5-9)21-8-20-15(17)14(21)13-11(18)2-1-3-12(13)19/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501713 (CHEMBL4069992) Show SMILES COc1ccc(cc1)-n1cnc(Cl)c1-c1c(F)cc(F)cc1F |(14.6,-5.48,;13.28,-6.26,;13.29,-7.8,;14.63,-8.56,;14.64,-10.1,;13.31,-10.88,;11.98,-10.13,;11.96,-8.59,;13.33,-12.42,;12.09,-13.33,;12.59,-14.79,;14.1,-14.79,;15.01,-16.03,;14.58,-13.31,;16.04,-12.83,;16.34,-11.33,;15.19,-10.31,;17.8,-10.84,;18.96,-11.86,;20.42,-11.38,;18.65,-13.37,;17.18,-13.86,;16.87,-15.36,)| Show InChI InChI=1S/C16H10ClF3N2O/c1-23-11-4-2-10(3-5-11)22-8-21-16(17)15(22)14-12(19)6-9(18)7-13(14)20/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM50353633 (CHEMBL1829813) Show SMILES CC(C)COC1=C(CC2CC2)C(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1 |c:5| Show InChI InChI=1S/C28H34ClNO4S/c1-19(2)18-34-27-17-23(28(31)26(27)16-21-6-7-21)15-22-5-3-4-20(14-22)12-13-30-35(32,33)25-10-8-24(29)9-11-25/h3-5,8-11,14,19,21,23,30H,6-7,12-13,15-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at mouse prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50026749 (CHEMBL3354617) Show SMILES CC(C)COC1=C(C(=O)C(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1)c1c(C)cccc1C |t:5| Show InChI InChI=1S/C34H38ClNO4S/c1-21(2)20-40-31-19-26(34(37)33(31)32-22(3)7-5-8-23(32)4)17-24-9-6-10-25-18-28(13-16-30(24)25)36-41(38,39)29-14-11-27(35)12-15-29/h5-12,14-15,21,26,28,36H,13,16-20H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity against human thromboxane A2 receptor alpha expressed in QBI-HEK293A cells assessed as reduction in I-BOP-induced inositol monoph...				ACS Med Chem Lett 5: 1015-20 (2014) Article DOI: 10.1021/ml5002085 BindingDB Entry DOI: 10.7270/Q27M09HF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50446539 (CHEMBL3110144) Show SMILES Cc1nn(-c2ccc(Cl)cc2Cl)c2c1c1C(=O)NC(=O)c1c1cccn21 Show InChI InChI=1S/C18H10Cl2N4O2/c1-8-13-15-14(16(25)21-17(15)26)12-3-2-6-23(12)18(13)24(22-8)11-5-4-9(19)7-10(11)20/h2-7H,1H3,(H,21,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK2 using ATP/Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay				J Med Chem 56: 10066-78 (2013) Article DOI: 10.1021/jm401466v BindingDB Entry DOI: 10.7270/Q2NC62PC
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501722 (CHEMBL4083158) Show SMILES Fc1ccc(F)c(-c2c(Cl)ncn2-c2ccc(Cl)cc2)c1F |(13.15,-8.82,;12.85,-10.32,;14,-11.35,;13.69,-12.86,;12.23,-13.34,;11.92,-14.85,;11.08,-12.31,;9.62,-12.8,;9.15,-14.27,;10.06,-15.52,;7.63,-14.28,;7.13,-12.82,;8.37,-11.9,;8.36,-10.36,;9.69,-9.59,;9.68,-8.05,;8.33,-7.29,;8.32,-5.75,;7,-8.08,;7.02,-9.61,;11.39,-10.81,;10.23,-9.79,)| Show InChI InChI=1S/C15H7Cl2F3N2/c16-8-1-3-9(4-2-8)22-7-21-15(17)14(22)12-10(18)5-6-11(19)13(12)20/h1-7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50353644 (CHEMBL1829809) Show SMILES CCC1=C(CC(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1=O)OCC(C)C |t:2| Show InChI InChI=1S/C26H32ClNO4S/c1-4-24-25(32-17-18(2)3)16-21(26(24)29)15-20-7-5-6-19(14-20)12-13-28-33(30,31)23-10-8-22(27)9-11-23/h5-11,14,18,21,28H,4,12-13,15-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid TP receptor expressed in QBI-HEK 293A cells assessed as inhibition of 1-BOP-induced increase in inositol mono...				J Med Chem 54: 6969-83 (2011) Article DOI: 10.1021/jm200980u BindingDB Entry DOI: 10.7270/Q2H995KG
					More data for this Ligand-Target Pair

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