Found 24 hits with Last Name = 'christ' and Initial = 'an' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300129
(CHEMBL572528 | CIBACRON BLUE | Cibacron Blue 3Ga)Show SMILES Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccccc4S(O)(=O)=O)n3)c(c2)S(O)(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S(O)(=O)=O Show InChI InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-16-7-3-4-8-19(16)49(40,41)42)37-29(36-27)34-17-10-9-13(11-20(17)50(43,44)45)32-18-12-21(51(46,47)48)24(31)23-22(18)25(38)14-5-1-2-6-15(14)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM21625
(2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole | 2-phen...)Show InChI InChI=1S/C12H9N3S/c1-2-4-9(5-3-1)12-13-8-11(16-12)10-6-7-14-15-10/h1-8H,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324491
(CHEMBL1215159 | N-Benzhydryl-5-(3-hydroxyphenyl)th...)Show SMILES Oc1cccc(c1)-c1ccc(s1)C(=O)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H19NO2S/c26-20-13-7-12-19(16-20)21-14-15-22(28-21)24(27)25-23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-16,23,26H,(H,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324482
(CHEMBL1215370 | N-(1-Amino-3-(1H-indol-3-yl)-1-oxo...)Show SMILES NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(cc1)-c1cccc(O)c1 Show InChI InChI=1S/C24H21N3O3/c25-23(29)22(13-18-14-26-21-7-2-1-6-20(18)21)27-24(30)16-10-8-15(9-11-16)17-4-3-5-19(28)12-17/h1-12,14,22,26,28H,13H2,(H2,25,29)(H,27,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324480
(CHEMBL1215516 | N-(1-Amino-1-oxo-3-phenylpropan-2-...)Show InChI InChI=1S/C19H17N3O2S/c20-18(23)16(11-13-5-2-1-3-6-13)22-19(24)14-8-9-15(21-12-14)17-7-4-10-25-17/h1-10,12,16H,11H2,(H2,20,23)(H,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324485
(CHEMBL1215297 | N-(1-Amino-3-(4-hydroxyphenyl)-1-o...)Show SMILES NC(=O)C(Cc1ccc(O)cc1)NC(=O)NC(=O)c1ccc(s1)-c1cccc(O)c1 Show InChI InChI=1S/C21H19N3O5S/c22-19(27)16(10-12-4-6-14(25)7-5-12)23-21(29)24-20(28)18-9-8-17(30-18)13-2-1-3-15(26)11-13/h1-9,11,16,25-26H,10H2,(H2,22,27)(H2,23,24,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM21624
(4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)Show InChI InChI=1S/C17H13FN2O3S/c1-9-6-10(2-5-13(9)18)14-8-24-17(20-14)19-11-3-4-12(16(22)23)15(21)7-11/h2-8,21H,1H3,(H,19,20)(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MMDB PC cid PC sid PDB UniChem
| MMDB PDB Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300128
(1-(3-(1H-tetrazol-5-yl)propyl)-4-(benzhydryloxy)pi...)Show SMILES C(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1 Show InChI InChI=1S/C22H27N5O/c1-3-8-18(9-4-1)22(19-10-5-2-6-11-19)28-20-13-16-27(17-14-20)15-7-12-21-23-25-26-24-21/h1-6,8-11,20,22H,7,12-17H2,(H,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
| MMDB PDB Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324490
(5-(3-Aminophenyl)-N-benzhydrylthiophene-2-carboxam...)Show SMILES Nc1cccc(c1)-c1ccc(s1)C(=O)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H20N2OS/c25-20-13-7-12-19(16-20)21-14-15-22(28-21)24(27)26-23(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-16,23H,25H2,(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324484
(CHEMBL1215298 | N-(1-Amino-3-(1H-indol-3-yl)-1-oxo...)Show SMILES NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(s1)-c1cccc(O)c1 Show InChI InChI=1S/C22H19N3O3S/c23-21(27)18(11-14-12-24-17-7-2-1-6-16(14)17)25-22(28)20-9-8-19(29-20)13-4-3-5-15(26)10-13/h1-10,12,18,24,26H,11H2,(H2,23,27)(H,25,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324486
(CHEMBL1215296 | N-(1-Amino-1-oxo-3-phenylpropan-2-...)Show SMILES NC(=O)C(Cc1ccccc1)NC(=O)NC(=O)c1ccc(s1)-c1cccc(O)c1 Show InChI InChI=1S/C21H19N3O4S/c22-19(26)16(11-13-5-2-1-3-6-13)23-21(28)24-20(27)18-10-9-17(29-18)14-7-4-8-15(25)12-14/h1-10,12,16,25H,11H2,(H2,22,26)(H2,23,24,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300128
(1-(3-(1H-tetrazol-5-yl)propyl)-4-(benzhydryloxy)pi...)Show SMILES C(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1 Show InChI InChI=1S/C22H27N5O/c1-3-8-18(9-4-1)22(19-10-5-2-6-11-19)28-20-13-16-27(17-14-20)15-7-12-21-23-25-26-24-21/h1-6,8-11,20,22H,7,12-17H2,(H,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
| MMDB PDB Article PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324483
(CHEMBL1215369 | N-(1-amino-1-oxo-3-phenylpropan-2-...)Show SMILES NC(=O)C(Cc1ccccc1)NC(=O)c1ccc(cc1)-c1cccc(O)c1 Show InChI InChI=1S/C22H20N2O3/c23-21(26)20(13-15-5-2-1-3-6-15)24-22(27)17-11-9-16(10-12-17)18-7-4-8-19(25)14-18/h1-12,14,20,25H,13H2,(H2,23,26)(H,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324487
(CHEMBL1215295 | N-(1-Amino-4-methyl-1-oxopentan-2-...)Show InChI InChI=1S/C17H20N2O3S/c1-10(2)8-13(16(18)21)19-17(22)15-7-6-14(23-15)11-4-3-5-12(20)9-11/h3-7,9-10,13,20H,8H2,1-2H3,(H2,18,21)(H,19,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324488
(CHEMBL1215294 | N-(2-Amino-2-oxoethyl)-5-(3-hydrox...)Show InChI InChI=1S/C13H12N2O3S/c14-12(17)7-15-13(18)11-5-4-10(19-11)8-2-1-3-9(16)6-8/h1-6,16H,7H2,(H2,14,17)(H,15,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300127
(CHEMBL567059 | NSC-4502 | phenyl(thiophen-2-yl)met...)Show InChI InChI=1S/C11H8OS/c12-11(10-7-4-8-13-10)9-5-2-1-3-6-9/h1-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324489
(CHEMBL1215162 | N-benzhydryl-2-(3-hydroxyphenyl)th...)Show SMILES Oc1cccc(c1)-c1nc(cs1)C(=O)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H18N2O2S/c26-19-13-7-12-18(14-19)23-24-20(15-28-23)22(27)25-21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-15,21,26H,(H,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300127
(CHEMBL567059 | NSC-4502 | phenyl(thiophen-2-yl)met...)Show InChI InChI=1S/C11H8OS/c12-11(10-7-4-8-13-10)9-5-2-1-3-6-9/h1-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324479
(5-amino-4-(3'-hydroxy-[1,1'-biphenyl]-4-ylcarboxam...)Show SMILES NC(=O)C(CCC(O)=O)NC(=O)c1cccc(c1)-c1cccc(O)c1 Show InChI InChI=1S/C18H18N2O5/c19-17(24)15(7-8-16(22)23)20-18(25)13-5-1-3-11(9-13)12-4-2-6-14(21)10-12/h1-6,9-10,15,21H,7-8H2,(H2,19,24)(H,20,25)(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50324481
(CHEMBL1215446 | N-(1-amino-1-oxo-3-phenylpropan-2-...)Show SMILES NC(=O)C(Cc1ccccc1)NC(=O)c1ccc(cc1O)-c1cccc(O)c1 Show InChI InChI=1S/C22H20N2O4/c23-21(27)19(11-14-5-2-1-3-6-14)24-22(28)18-10-9-16(13-20(18)26)15-7-4-8-17(25)12-15/h1-10,12-13,19,25-26H,11H2,(H2,23,27)(H,24,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay |
J Med Chem 53: 5536-48 (2010)
Article DOI: 10.1021/jm100194a BindingDB Entry DOI: 10.7270/Q21J99Z4 |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300126
(CHEMBL574431 | Sulfobromophthalein)Show SMILES Oc1ccc(cc1S(O)(=O)=O)C1(OC(=O)c2c1c(Br)c(Br)c(Br)c2Br)c1ccc(O)c(c1)S(O)(=O)=O Show InChI InChI=1S/C20H10Br4O10S2/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33/h1-6,25-26H,(H,28,29,30)(H,31,32,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300125
((4-methoxyphenyl)(thiophen-2-yl)methanone | CHEMBL...)Show InChI InChI=1S/C12H10O2S/c1-14-10-6-4-9(5-7-10)12(13)11-3-2-8-15-11/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50186231
((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)Show InChI InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50300124
((5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic ...)Show InChI InChI=1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation |
Eur J Med Chem 45: 447-54 (2010)
Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT |
More data for this Ligand-Target Pair | |