Found 402 hits with Last Name = 'gaudet' and Initial = 'm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin D2 receptor 2
(Mus musculus (mouse)) | BDBM50356677
(CHEMBL1917592)Show SMILES CCCS(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H16ClFO5S/c1-2-9-27(24,25)16-6-7-17(21)13(11-16)3-4-14-10-15(20)5-8-18(14)26-12-19(22)23/h5-8,10-11H,2,9,12H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384475
(CHEMBL2036225)Show SMILES CS(=O)(=O)c1ccc(CN(C(=O)Cc2ccccc2)c2cc(F)cc(c2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C23H20FN5O3S/c1-33(31,32)21-9-7-17(8-10-21)15-29(22(30)11-16-5-3-2-4-6-16)20-13-18(12-19(24)14-20)23-25-27-28-26-23/h2-10,12-14H,11,15H2,1H3,(H,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356751
(CHEMBL1917804)Show SMILES CCCS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OC(C)C(O)=O Show InChI InChI=1S/C21H21ClO5S/c1-4-11-28(25,26)19-9-5-14(2)16(13-19)6-7-17-12-18(22)8-10-20(17)27-15(3)21(23)24/h5,8-10,12-13,15H,4,11H2,1-3H3,(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356729
(CHEMBL1917782)Show SMILES CCCS(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(O)=O)c(C)cc1NC(C)=O Show InChI InChI=1S/C22H22ClNO6S/c1-4-9-31(28,29)21-12-16(14(2)10-19(21)24-15(3)25)5-6-17-11-18(23)7-8-20(17)30-13-22(26)27/h7-8,10-12H,4,9,13H2,1-3H3,(H,24,25)(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356693
(CHEMBL1917608)Show SMILES CC1CCCCN1S(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-16-6-10-21(31(28,29)25-12-4-3-5-17(25)2)14-18(16)7-8-19-13-20(24)9-11-22(19)30-15-23(26)27/h6,9-11,13-14,17H,3-5,12,15H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384482
(CHEMBL2036207)Show SMILES CCCCC(=O)N(Cc1ccc2OCCOc2c1)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C21H22FN5O3/c1-2-3-4-20(28)27(13-14-5-6-18-19(9-14)30-8-7-29-18)17-11-15(10-16(22)12-17)21-23-25-26-24-21/h5-6,9-12H,2-4,7-8,13H2,1H3,(H,23,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356669
(CHEMBL1917584)Show SMILES CCCS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C20H19ClO5S/c1-3-10-27(24,25)18-8-4-14(2)15(12-18)5-6-16-11-17(21)7-9-19(16)26-13-20(22)23/h4,7-9,11-12H,3,10,13H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356679
(CHEMBL1917594)Show SMILES CCCS(=O)(=O)c1ccc(Cl)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H16Cl2O5S/c1-2-9-27(24,25)16-6-7-17(21)13(11-16)3-4-14-10-15(20)5-8-18(14)26-12-19(22)23/h5-8,10-11H,2,9,12H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384515
(CHEMBL2036224)Show SMILES CS(=O)(=O)c1ccc(CN(C(=O)c2ccccc2)c2cc(F)cc(c2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C22H18FN5O3S/c1-32(30,31)20-9-7-15(8-10-20)14-28(22(29)16-5-3-2-4-6-16)19-12-17(11-18(23)13-19)21-24-26-27-25-21/h2-13H,14H2,1H3,(H,24,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384465
(CHEMBL2036211)Show SMILES CCCCC(=O)N(Cc1ccc(cc1)C(F)(F)F)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H19F4N5O/c1-2-3-4-18(30)29(12-13-5-7-15(8-6-13)20(22,23)24)17-10-14(9-16(21)11-17)19-25-27-28-26-19/h5-11H,2-4,12H2,1H3,(H,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Mus musculus (mouse)) | BDBM50356669
(CHEMBL1917584)Show SMILES CCCS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C20H19ClO5S/c1-3-10-27(24,25)18-8-4-14(2)15(12-18)5-6-16-11-17(21)7-9-19(16)26-13-20(22)23/h4,7-9,11-12H,3,10,13H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384516
(CHEMBL2036226)Show SMILES Cc1ccc(CCC(=O)N(Cc2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(c2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C25H24FN5O3S/c1-17-3-5-18(6-4-17)9-12-24(32)31(16-19-7-10-23(11-8-19)35(2,33)34)22-14-20(13-21(26)15-22)25-27-29-30-28-25/h3-8,10-11,13-15H,9,12,16H2,1-2H3,(H,27,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356680
(CHEMBL1917595)Show SMILES CC(C)S(=O)(=O)c1ccc(Cl)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H16Cl2O5S/c1-12(2)27(24,25)16-6-7-17(21)13(10-16)3-4-14-9-15(20)5-8-18(14)26-11-19(22)23/h5-10,12H,11H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384495
(CHEMBL2036025)Show SMILES CCCCC(=O)N(Cc1cccc(OC)c1)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H22FN5O2/c1-3-4-8-19(27)26(13-14-6-5-7-18(9-14)28-2)17-11-15(10-16(21)12-17)20-22-24-25-23-20/h5-7,9-12H,3-4,8,13H2,1-2H3,(H,22,23,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384497
(CHEMBL2036028)Show SMILES CCCCC(=O)N(Cc1ccc(OC)cc1)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H22FN5O2/c1-3-4-5-19(27)26(13-14-6-8-18(28-2)9-7-14)17-11-15(10-16(21)12-17)20-22-24-25-23-20/h6-12H,3-5,13H2,1-2H3,(H,22,23,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356749
(CHEMBL1917802)Show SMILES CCCS(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OC(C)C(O)=O Show InChI InChI=1S/C20H18ClFO5S/c1-3-10-28(25,26)17-7-8-18(22)14(12-17)4-5-15-11-16(21)6-9-19(15)27-13(2)20(23)24/h6-9,11-13H,3,10H2,1-2H3,(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356671
(CHEMBL1917586)Show SMILES CC(C)CS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C21H21ClO5S/c1-14(2)13-28(25,26)19-8-4-15(3)16(11-19)5-6-17-10-18(22)7-9-20(17)27-12-21(23)24/h4,7-11,14H,12-13H2,1-3H3,(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356683
(CHEMBL1917598)Show SMILES CN(C)S(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C18H15ClFNO5S/c1-21(2)27(24,25)15-6-7-16(20)12(10-15)3-4-13-9-14(19)5-8-17(13)26-11-18(22)23/h5-10H,11H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384472
(CHEMBL2036220)Show SMILES CCC(=O)N(Cc1ccc(cc1)S(C)(=O)=O)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C18H18FN5O3S/c1-3-17(25)24(11-12-4-6-16(7-5-12)28(2,26)27)15-9-13(8-14(19)10-15)18-20-22-23-21-18/h4-10H,3,11H2,1-2H3,(H,20,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384473
(CHEMBL2036222)Show SMILES CC(C)CC(=O)N(Cc1ccc(cc1)S(C)(=O)=O)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H22FN5O3S/c1-13(2)8-19(27)26(12-14-4-6-18(7-5-14)30(3,28)29)17-10-15(9-16(21)11-17)20-22-24-25-23-20/h4-7,9-11,13H,8,12H2,1-3H3,(H,22,23,24,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356703
(CHEMBL1917618)Show InChI InChI=1S/C17H13ClO4S/c1-23(21)15-4-2-3-12(9-15)5-6-13-10-14(18)7-8-16(13)22-11-17(19)20/h2-4,7-10H,11H2,1H3,(H,19,20) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384487
(CHEMBL2036016)Show SMILES CCCCC(=O)N(Cc1ccc2OCCOc2c1)c1cc(ccc1F)-c1nnn[nH]1 Show InChI InChI=1S/C21H22FN5O3/c1-2-3-4-20(28)27(13-14-5-8-18-19(11-14)30-10-9-29-18)17-12-15(6-7-16(17)22)21-23-25-26-24-21/h5-8,11-12H,2-4,9-10,13H2,1H3,(H,23,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356664
(CHEMBL1917579)Show SMILES CS(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C17H12ClFO5S/c1-25(22,23)14-5-6-15(19)11(9-14)2-3-12-8-13(18)4-7-16(12)24-10-17(20)21/h4-9H,10H2,1H3,(H,20,21) | PDB
Reactome pathway
KEGG
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| Article
PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356684
(CHEMBL1917599)Show SMILES CCN(CC)S(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C21H22ClNO5S/c1-4-23(5-2)29(26,27)19-10-6-15(3)16(13-19)7-8-17-12-18(22)9-11-20(17)28-14-21(24)25/h6,9-13H,4-5,14H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356677
(CHEMBL1917592)Show SMILES CCCS(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H16ClFO5S/c1-2-9-27(24,25)16-6-7-17(21)13(11-16)3-4-14-10-15(20)5-8-18(14)26-12-19(22)23/h5-8,10-11H,2,9,12H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356688
(CHEMBL1917603)Show SMILES CC(C)NS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C20H20ClNO5S/c1-13(2)22-28(25,26)18-8-4-14(3)15(11-18)5-6-16-10-17(21)7-9-19(16)27-12-20(23)24/h4,7-11,13,22H,12H2,1-3H3,(H,23,24) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356665
(CHEMBL1917580)Show SMILES CS(=O)(=O)c1ccc(Cl)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C17H12Cl2O5S/c1-25(22,23)14-5-6-15(19)11(9-14)2-3-12-8-13(18)4-7-16(12)24-10-17(20)21/h4-9H,10H2,1H3,(H,20,21) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356728
(CHEMBL1917781)Show SMILES CS(=O)(=O)c1cc(ccc1-c1ccccc1Cl)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C23H16Cl2O5S/c1-31(28,29)22-12-15(7-10-19(22)18-4-2-3-5-20(18)25)6-8-16-13-17(24)9-11-21(16)30-14-23(26)27/h2-5,7,9-13H,14H2,1H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384484
(CHEMBL2036029)Show SMILES CCCCC(=O)N(Cc1ccc(OC)cc1)c1cc(Cl)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H22ClN5O2/c1-3-4-5-19(27)26(13-14-6-8-18(28-2)9-7-14)17-11-15(10-16(21)12-17)20-22-24-25-23-20/h6-12H,3-5,13H2,1-2H3,(H,22,23,24,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356692
(CHEMBL1917607)Show SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C21H20ClNO6S/c1-15-2-6-19(30(26,27)23-8-10-28-11-9-23)13-16(15)3-4-17-12-18(22)5-7-20(17)29-14-21(24)25/h2,5-7,12-13H,8-11,14H2,1H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356695
(CHEMBL1917610)Show SMILES COCCNS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C20H20ClNO6S/c1-14-3-7-18(29(25,26)22-9-10-27-2)12-15(14)4-5-16-11-17(21)6-8-19(16)28-13-20(23)24/h3,6-8,11-12,22H,9-10,13H2,1-2H3,(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM21599
(2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...)Show SMILES Cc1noc(c1CN1CC2(CC1=O)C(=O)N(CC(O)=O)c1ccc(Cl)cc21)-c1ccccc1 Show InChI InChI=1S/C24H20ClN3O5/c1-14-17(22(33-26-14)15-5-3-2-4-6-15)11-27-13-24(10-20(27)29)18-9-16(25)7-8-19(18)28(23(24)32)12-21(30)31/h2-9H,10-13H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 3.80 | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Merck Serono
| Assay Description
A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc... |
J Med Chem 51: 2227-2243 (2008)
Article DOI: 10.1021/jm701383e
BindingDB Entry DOI: 10.7270/Q22R3PZS |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356689
(CHEMBL1917604)Show SMILES CC(C)N(C)S(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C21H22ClNO5S/c1-14(2)23(4)29(26,27)19-9-5-15(3)16(12-19)6-7-17-11-18(22)8-10-20(17)28-13-21(24)25/h5,8-12,14H,13H2,1-4H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM21599
(2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...)Show SMILES Cc1noc(c1CN1CC2(CC1=O)C(=O)N(CC(O)=O)c1ccc(Cl)cc21)-c1ccccc1 Show InChI InChI=1S/C24H20ClN3O5/c1-14-17(22(33-26-14)15-5-3-2-4-6-15)11-27-13-24(10-20(27)29)18-9-16(25)7-8-19(18)28(23(24)32)12-21(30)31/h2-9H,10-13H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in CHO cells after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 644-649 (2011)
Article DOI: 10.1021/ml2001196
BindingDB Entry DOI: 10.7270/Q28916X5 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384478
(CHEMBL2036228)Show SMILES CS(=O)(=O)c1ccc(CN(C(=O)c2cccnc2)c2cc(F)cc(c2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C21H17FN6O3S/c1-32(30,31)19-6-4-14(5-7-19)13-28(21(29)15-3-2-8-23-12-15)18-10-16(9-17(22)11-18)20-24-26-27-25-20/h2-12H,13H2,1H3,(H,24,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356678
(CHEMBL1917593)Show SMILES CC(C)S(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H16ClFO5S/c1-12(2)27(24,25)16-6-7-17(21)13(10-16)3-4-14-9-15(20)5-8-18(14)26-11-19(22)23/h5-10,12H,11H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356694
(CHEMBL1917609)Show SMILES COCCN(C)S(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C21H22ClNO6S/c1-15-4-8-19(30(26,27)23(2)10-11-28-3)13-16(15)5-6-17-12-18(22)7-9-20(17)29-14-21(24)25/h4,7-9,12-13H,10-11,14H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356690
(CHEMBL1917605)Show SMILES CC(C)CN(C)S(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C22H24ClNO5S/c1-15(2)13-24(4)30(27,28)20-9-5-16(3)17(12-20)6-7-18-11-19(23)8-10-21(18)29-14-22(25)26/h5,8-12,15H,13-14H2,1-4H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356760
(CHEMBL1917408)Show InChI InChI=1S/C18H16ClNO3/c1-2-3-13-8-9-20-11-15(13)5-4-14-10-16(19)6-7-17(14)23-12-18(21)22/h6-11H,2-3,12H2,1H3,(H,21,22) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356687
(CHEMBL1917602)Show SMILES CCNS(=O)(=O)c1ccc(C)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C19H18ClNO5S/c1-3-21-27(24,25)17-8-4-13(2)14(11-17)5-6-15-10-16(20)7-9-18(15)26-12-19(22)23/h4,7-11,21H,3,12H2,1-2H3,(H,22,23) | PDB
Reactome pathway
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PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384466
(CHEMBL2036212)Show SMILES CCCCC(=O)N(Cc1cccc(OC(F)(F)F)c1)c1cc(F)cc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C20H19F4N5O2/c1-2-3-7-18(30)29(12-13-5-4-6-17(8-13)31-20(22,23)24)16-10-14(9-15(21)11-16)19-25-27-28-26-19/h4-6,8-11H,2-3,7,12H2,1H3,(H,25,26,27,28) | PDB
Reactome pathway
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| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356667
(CHEMBL1917582)Show SMILES CC(C)c1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(C)(=O)=O Show InChI InChI=1S/C20H19ClO5S/c1-13(2)18-8-7-17(27(3,24)25)11-14(18)4-5-15-10-16(21)6-9-19(15)26-12-20(22)23/h6-11,13H,12H2,1-3H3,(H,22,23) | PDB
Reactome pathway
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PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50384508
(CHEMBL2036206)Show SMILES CCCC(=O)N(Cc1ccc2OCCOc2c1)c1cc(ccc1F)-c1nnn[nH]1 Show InChI InChI=1S/C20H20FN5O3/c1-2-3-19(27)26(12-13-4-7-17-18(10-13)29-9-8-28-17)16-11-14(5-6-15(16)21)20-22-24-25-23-20/h4-7,10-11H,2-3,8-9,12H2,1H3,(H,22,23,24,25) | PDB
Reactome pathway
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| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay |
ACS Med Chem Lett 2: 938-942 (2011)
Article DOI: 10.1021/ml200223s
BindingDB Entry DOI: 10.7270/Q2Z89DGQ |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356761
(CHEMBL1917409)Show InChI InChI=1S/C19H18ClNO3/c1-13(2)9-14-7-8-21-11-16(14)4-3-15-10-17(20)5-6-18(15)24-12-19(22)23/h5-8,10-11,13H,9,12H2,1-2H3,(H,22,23) | PDB
Reactome pathway
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| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356685
(CHEMBL1917600)Show SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C21H22ClNO5S/c1-14-5-9-18(29(26,27)23-21(2,3)4)12-15(14)6-7-16-11-17(22)8-10-19(16)28-13-20(24)25/h5,8-12,23H,13H2,1-4H3,(H,24,25) | PDB
Reactome pathway
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356765
(CHEMBL1917810)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1ccc(OC)cn1)C(=O)C1CC1 Show InChI InChI=1S/C28H30N2O5/c1-4-30(28(33)19-6-7-19)17-21-15-20(25-11-9-22(34-2)16-29-25)8-10-23(21)24-13-18(14-27(31)32)5-12-26(24)35-3/h5,8-13,15-16,19H,4,6-7,14,17H2,1-3H3,(H,31,32) | PDB
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Mus musculus (mouse)) | BDBM21610
(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)Show SMILES OC(=O)CN1C(=O)[C@@]2(CC(=O)N(Cc3cc(Cl)ccc3F)C2=O)c2cc(Cl)ccc12 |r| Show InChI InChI=1S/C20H13Cl2FN2O5/c21-11-1-3-14(23)10(5-11)8-25-16(26)7-20(19(25)30)13-6-12(22)2-4-15(13)24(18(20)29)9-17(27)28/h1-6H,7-9H2,(H,27,28)/t20-/m1/s1 | PDB
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono
| Assay Description
A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc... |
J Med Chem 51: 2227-2243 (2008)
Article DOI: 10.1021/jm701383e
BindingDB Entry DOI: 10.7270/Q22R3PZS |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356691
(CHEMBL1917606)Show SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C22H22ClNO5S/c1-16-5-9-20(30(27,28)24-11-3-2-4-12-24)14-17(16)6-7-18-13-19(23)8-10-21(18)29-15-22(25)26/h5,8-10,13-14H,2-4,11-12,15H2,1H3,(H,25,26) | PDB
Reactome pathway
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356722
(CHEMBL1917636)Show SMILES CS(=O)(=O)c1cc(ccc1-c1ccccc1)C#Cc1cc(Cl)ccc1OCC(O)=O Show InChI InChI=1S/C23H17ClO5S/c1-30(27,28)22-13-16(8-11-20(22)17-5-3-2-4-6-17)7-9-18-14-19(24)10-12-21(18)29-15-23(25)26/h2-6,8,10-14H,15H2,1H3,(H,25,26) | PDB
Reactome pathway
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50356663
(CHEMBL1917578)Show SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(C)(=O)=O Show InChI InChI=1S/C18H15ClO5S/c1-12-3-7-16(25(2,22)23)10-13(12)4-5-14-9-15(19)6-8-17(14)24-11-18(20)21/h3,6-10H,11H2,1-2H3,(H,20,21) | PDB
Reactome pathway
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono S.A.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting |
J Med Chem 54: 7299-317 (2011)
Article DOI: 10.1021/jm200866y
BindingDB Entry DOI: 10.7270/Q2N58MS1 |
More data for this
Ligand-Target Pair | |
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