Compile Data Set for Download or QSAR

Found 51 hits with Last Name = 'gordon' and Initial = 'dw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(COc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H21F3N4O2/c1-12-10-22-7-8-25(12)15-9-17(26)24(2)16(23-15)11-27-14-6-4-3-5-13(14)18(19,20)21/h3-6,9,12,22H,7-8,10-11H2,1-2H3/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286792 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C34H45N5O5/c1-23(2)19-27(37-34(44)39-17-11-4-5-12-18-39)31(40)35-28(21-25-22-38(3)30-16-10-9-15-26(25)30)32(41)36-29(33(42)43)20-24-13-7-6-8-14-24/h6-10,13-16,22-23,27-29H,4-5,11-12,17-21H2,1-3H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t27-,28+,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286804 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1ccccn1)C(O)=O Show InChI InChI=1S/C33H44N6O5/c1-22(2)18-26(37-33(44)39-16-10-4-5-11-17-39)30(40)35-27(19-23-21-38(3)29-14-7-6-13-25(23)29)31(41)36-28(32(42)43)20-24-12-8-9-15-34-24/h6-9,12-15,21-22,26-28H,4-5,10-11,16-20H2,1-3H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t26-,27+,28+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286800 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CO)C(O)=O Show InChI InChI=1S/C28H41N5O6/c1-18(2)14-21(31-28(39)33-12-8-4-5-9-13-33)25(35)29-22(26(36)30-23(17-34)27(37)38)15-19-16-32(3)24-11-7-6-10-20(19)24/h6-7,10-11,16,18,21-23,34H,4-5,8-9,12-15,17H2,1-3H3,(H,29,35)(H,30,36)(H,31,39)(H,37,38)/t21-,22+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286795 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(O)=O Show InChI InChI=1S/C37H48N6O5/c1-24(2)19-29(40-37(48)43-17-11-5-6-12-18-43)34(44)38-30(20-25-22-41(3)32-15-9-7-13-27(25)32)35(45)39-31(36(46)47)21-26-23-42(4)33-16-10-8-14-28(26)33/h7-10,13-16,22-24,29-31H,5-6,11-12,17-21H2,1-4H3,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t29-,30+,31+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286802 (3-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCC(O)=O Show InChI InChI=1S/C28H41N5O5/c1-19(2)16-22(31-28(38)33-14-8-4-5-9-15-33)27(37)30-23(26(36)29-13-12-25(34)35)17-20-18-32(3)24-11-7-6-10-21(20)24/h6-7,10-11,18-19,22-23H,4-5,8-9,12-17H2,1-3H3,(H,29,36)(H,30,37)(H,31,38)(H,34,35)/t22-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286791 (4-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCC(O)=O Show InChI InChI=1S/C29H43N5O5/c1-20(2)17-23(32-29(39)34-15-8-4-5-9-16-34)28(38)31-24(27(37)30-14-10-13-26(35)36)18-21-19-33(3)25-12-7-6-11-22(21)25/h6-7,11-12,19-20,23-24H,4-5,8-10,13-18H2,1-3H3,(H,30,37)(H,31,38)(H,32,39)(H,35,36)/t23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286805 (CHEMBL170121 | [(R)-2-{(S)-2-[(Azepane-1-carbonyl)...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCC(O)=O Show InChI InChI=1S/C27H39N5O5/c1-18(2)14-21(30-27(37)32-12-8-4-5-9-13-32)26(36)29-22(25(35)28-16-24(33)34)15-19-17-31(3)23-11-7-6-10-20(19)23/h6-7,10-11,17-18,21-22H,4-5,8-9,12-16H2,1-3H3,(H,28,35)(H,29,36)(H,30,37)(H,33,34)/t21-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286793 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C29H41N5O7/c1-18(2)14-21(32-29(41)34-12-8-4-5-9-13-34)26(37)30-22(27(38)31-23(28(39)40)16-25(35)36)15-19-17-33(3)24-11-7-6-10-20(19)24/h6-7,10-11,17-18,21-23H,4-5,8-9,12-16H2,1-3H3,(H,30,37)(H,31,38)(H,32,41)(H,35,36)(H,39,40)/t21-,22+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286801 (3-(3-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCc1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C35H47N5O5/c1-24(2)19-29(38-35(45)40-17-8-4-5-9-18-40)34(44)37-30(21-27-23-39(3)31-14-7-6-13-28(27)31)33(43)36-22-26-12-10-11-25(20-26)15-16-32(41)42/h6-7,10-14,20,23-24,29-30H,4-5,8-9,15-19,21-22H2,1-3H3,(H,36,43)(H,37,44)(H,38,45)(H,41,42)/t29-,30+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286798 (2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NC(C)(C)C(O)=O Show InChI InChI=1S/C29H43N5O5/c1-19(2)16-22(31-28(39)34-14-10-6-7-11-15-34)25(35)30-23(26(36)32-29(3,4)27(37)38)17-20-18-33(5)24-13-9-8-12-21(20)24/h8-9,12-13,18-19,22-23H,6-7,10-11,14-17H2,1-5H3,(H,30,35)(H,31,39)(H,32,36)(H,37,38)/t22-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286794 (2-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-me...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCc1nc(cs1)C(O)=O Show InChI InChI=1S/C30H40N6O5S/c1-19(2)14-22(34-30(41)36-12-8-4-5-9-13-36)28(38)33-23(15-20-17-35(3)25-11-7-6-10-21(20)25)27(37)31-16-26-32-24(18-42-26)29(39)40/h6-7,10-11,17-19,22-23H,4-5,8-9,12-16H2,1-3H3,(H,31,37)(H,33,38)(H,34,41)(H,39,40)/t22-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286803 ((S)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1cn(C)c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1)C(O)=O Show InChI InChI=1S/C31H47N5O5/c1-20(2)16-24(34-31(41)36-14-10-6-7-11-15-36)28(37)32-25(29(38)33-26(30(39)40)17-21(3)4)18-22-19-35(5)27-13-9-8-12-23(22)27/h8-9,12-13,19-21,24-26H,6-7,10-11,14-18H2,1-5H3,(H,32,37)(H,33,38)(H,34,41)(H,39,40)/t24-,25+,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286797 ((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CC(N)=O)C(O)=O Show InChI InChI=1S/C29H42N6O6/c1-18(2)14-21(33-29(41)35-12-8-4-5-9-13-35)26(37)31-22(27(38)32-23(28(39)40)16-25(30)36)15-19-17-34(3)24-11-7-6-10-20(19)24/h6-7,10-11,17-18,21-23H,4-5,8-9,12-16H2,1-3H3,(H2,30,36)(H,31,37)(H,32,38)(H,33,41)(H,39,40)/t21-,22+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286796 (5-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCCC(O)=O Show InChI InChI=1S/C30H45N5O5/c1-21(2)18-24(33-30(40)35-16-10-4-5-11-17-35)29(39)32-25(28(38)31-15-9-8-14-27(36)37)19-22-20-34(3)26-13-7-6-12-23(22)26/h6-7,12-13,20-21,24-25H,4-5,8-11,14-19H2,1-3H3,(H,31,38)(H,32,39)(H,33,40)(H,36,37)/t24-,25+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50286799 (6-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...) Show SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCCCC(O)=O Show InChI InChI=1S/C31H47N5O5/c1-22(2)19-25(34-31(41)36-17-11-4-5-12-18-36)30(40)33-26(29(39)32-16-10-6-7-15-28(37)38)20-23-21-35(3)27-14-9-8-13-24(23)27/h8-9,13-14,21-22,25-26H,4-7,10-12,15-20H2,1-3H3,(H,32,39)(H,33,40)(H,34,41)(H,37,38)/t25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.				Bioorg Med Chem Lett 5: 917-922 (1995) Article DOI: 10.1016/0960-894X(95)00144-I BindingDB Entry DOI: 10.7270/Q28S4PWG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301785 ((R)-2-(2-chlorophenethyl)-3-methyl-6-(2-methylpipe...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(CCc2ccccc2Cl)n1 |r| Show InChI InChI=1S/C18H23ClN4O/c1-13-12-20-9-10-23(13)17-11-18(24)22(2)16(21-17)8-7-14-5-3-4-6-15(14)19/h3-6,11,13,20H,7-10,12H2,1-2H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301786 ((R)-3-methyl-2-(2-methylphenethyl)-6-(2-methylpipe...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(CCc2ccccc2C)n1 |r| Show InChI InChI=1S/C19H26N4O/c1-14-6-4-5-7-16(14)8-9-17-21-18(12-19(24)22(17)3)23-11-10-20-13-15(23)2/h4-7,12,15,20H,8-11,13H2,1-3H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301787 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-(2-(trif...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(CCc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C19H23F3N4O/c1-13-12-23-9-10-26(13)17-11-18(27)25(2)16(24-17)8-7-14-5-3-4-6-15(14)19(20,21)22/h3-6,11,13,23H,7-10,12H2,1-2H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301788 (6-methyl-3-(3-phenylpropyl)-2-(piperazin-1-yl)pyri...) Show SMILES Cc1cc(=O)n(CCCc2ccccc2)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H24N4O/c1-15-14-17(23)22(11-5-8-16-6-3-2-4-7-16)18(20-15)21-12-9-19-10-13-21/h2-4,6-7,14,19H,5,8-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301789 (3-(3-(benzyloxy)propyl)-6-methyl-2-(piperazin-1-yl...) Show SMILES Cc1cc(=O)n(CCCOCc2ccccc2)c(n1)N1CCNCC1 Show InChI InChI=1S/C19H26N4O2/c1-16-14-18(24)23(19(21-16)22-11-8-20-9-12-22)10-5-13-25-15-17-6-3-2-4-7-17/h2-4,6-7,14,20H,5,8-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301790 (2-(2-chlorophenethyl)-3-ethyl-6-(piperazin-1-yl)py...) Show SMILES CCn1c(CCc2ccccc2Cl)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C18H23ClN4O/c1-2-23-16(8-7-14-5-3-4-6-15(14)19)21-17(13-18(23)24)22-11-9-20-10-12-22/h3-6,13,20H,2,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301791 (3-methyl-6-(piperazin-1-yl)-2-((2-(trifluoromethyl...) Show SMILES Cn1c(COc2ccccc2C(F)(F)F)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H19F3N4O2/c1-23-15(11-26-13-5-3-2-4-12(13)17(18,19)20)22-14(10-16(23)25)24-8-6-21-7-9-24/h2-5,10,21H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301792 (2-((2-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) Show SMILES Cn1c(COc2ccccc2Cl)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C16H19ClN4O2/c1-20-15(11-23-13-5-3-2-4-12(13)17)19-14(10-16(20)22)21-8-6-18-7-9-21/h2-5,10,18H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301793 (3-methyl-6-(piperazin-1-yl)-2-(o-tolyloxymethyl)py...) Show SMILES Cc1ccccc1OCc1nc(cc(=O)n1C)N1CCNCC1 Show InChI InChI=1S/C17H22N4O2/c1-13-5-3-4-6-14(13)23-12-16-19-15(11-17(22)20(16)2)21-9-7-18-8-10-21/h3-6,11,18H,7-10,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	228	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301794 (3-methyl-6-(piperazin-1-yl)-2-((3-(trifluoromethyl...) Show SMILES Cn1c(COc2cccc(c2)C(F)(F)F)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H19F3N4O2/c1-23-15(11-26-13-4-2-3-12(9-13)17(18,19)20)22-14(10-16(23)25)24-7-5-21-6-8-24/h2-4,9-10,21H,5-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	487	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301795 (2-((3-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) Show SMILES Cn1c(COc2cccc(Cl)c2)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C16H19ClN4O2/c1-20-15(11-23-13-4-2-3-12(17)9-13)19-14(10-16(20)22)21-7-5-18-6-8-21/h2-4,9-10,18H,5-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	493	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301796 (3-((1-methyl-6-oxo-4-(piperazin-1-yl)-1,6-dihydrop...) Show SMILES Cn1c(COc2cccc(c2)C#N)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H19N5O2/c1-21-16(12-24-14-4-2-3-13(9-14)11-18)20-15(10-17(21)23)22-7-5-19-6-8-22/h2-4,9-10,19H,5-8,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	319	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301797 (3-methyl-6-(piperazin-1-yl)-2-((4-(trifluoromethyl...) Show SMILES Cn1c(COc2ccc(cc2)C(F)(F)F)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H19F3N4O2/c1-23-15(11-26-13-4-2-12(3-5-13)17(18,19)20)22-14(10-16(23)25)24-8-6-21-7-9-24/h2-5,10,21H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301798 (2-((4-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C16H19ClN4O2/c1-20-15(11-23-13-4-2-12(17)3-5-13)19-14(10-16(20)22)21-8-6-18-7-9-21/h2-5,10,18H,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301799 (2-((5-fluoro-2-methylphenoxy)methyl)-3-methyl-6-(p...) Show SMILES Cc1ccc(F)cc1OCc1nc(cc(=O)n1C)N1CCNCC1 Show InChI InChI=1S/C17H21FN4O2/c1-12-3-4-13(18)9-14(12)24-11-16-20-15(10-17(23)21(16)2)22-7-5-19-6-8-22/h3-4,9-10,19H,5-8,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301800 (2-((5-chloro-2-methylphenoxy)methyl)-3-methyl-6-(p...) Show SMILES Cc1ccc(Cl)cc1OCc1nc(cc(=O)n1C)N1CCNCC1 Show InChI InChI=1S/C17H21ClN4O2/c1-12-3-4-13(18)9-14(12)24-11-16-20-15(10-17(23)21(16)2)22-7-5-19-6-8-22/h3-4,9-10,19H,5-8,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301801 (2-((2-chloro-5-fluorophenoxy)methyl)-3-methyl-6-(p...) Show SMILES Cn1c(COc2cc(F)ccc2Cl)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C16H18ClFN4O2/c1-21-15(10-24-13-8-11(18)2-3-12(13)17)20-14(9-16(21)23)22-6-4-19-5-7-22/h2-3,8-9,19H,4-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	361	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301802 (3-((1-ethyl-6-oxo-4-(piperazin-1-yl)-1,6-dihydropy...) Show SMILES CCn1c(COc2cccc(c2)C#N)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C18H21N5O2/c1-2-23-17(13-25-15-5-3-4-14(10-15)12-19)21-16(11-18(23)24)22-8-6-20-7-9-22/h3-5,10-11,20H,2,6-9,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301784 ((R)-2-(3-chlorophenethyl)-3-methyl-6-(2-methylpipe...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(CCc2cccc(Cl)c2)n1 |r| Show InChI InChI=1S/C18H23ClN4O/c1-13-12-20-8-9-23(13)17-11-18(24)22(2)16(21-17)7-6-14-4-3-5-15(19)10-14/h3-5,10-11,13,20H,6-9,12H2,1-2H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301783 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-phenethy...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(CCc2ccccc2)n1 |r| Show InChI InChI=1S/C18H24N4O/c1-14-13-19-10-11-22(14)17-12-18(23)21(2)16(20-17)9-8-15-6-4-3-5-7-15/h3-7,12,14,19H,8-11,13H2,1-2H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	262	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301782 (2-(3-chlorophenethyl)-3-methyl-6-(piperazin-1-yl)p...) Show SMILES Cn1c(CCc2cccc(Cl)c2)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H21ClN4O/c1-21-15(6-5-13-3-2-4-14(18)11-13)20-16(12-17(21)23)22-9-7-19-8-10-22/h2-4,11-12,19H,5-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301781 (3-methyl-2-phenethyl-6-(piperazin-1-yl)pyrimidin-4...) Show SMILES Cn1c(CCc2ccccc2)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H22N4O/c1-20-15(8-7-14-5-3-2-4-6-14)19-16(13-17(20)22)21-11-9-18-10-12-21/h2-6,13,18H,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	275	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301780 (6-methyl-2-((R)-2-methylpiperazin-1-yl)-3-(3-pheno...) Show SMILES C[C@@H]1CNCCN1c1nc(C)cc(=O)n1CCCOc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O2/c1-15-13-18(24)23(10-6-12-25-17-7-4-3-5-8-17)19(21-15)22-11-9-20-14-16(22)2/h3-5,7-8,13,16,20H,6,9-12,14H2,1-2H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	163	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301779 (3-(3-(4-chlorophenoxy)propyl)-6-methyl-2-(piperazi...) Show SMILES Cc1cc(=O)n(CCCOc2ccc(Cl)cc2)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H23ClN4O2/c1-14-13-17(24)23(18(21-14)22-10-7-20-8-11-22)9-2-12-25-16-5-3-15(19)4-6-16/h3-6,13,20H,2,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	899	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301803 (2-((2-chloro-5-fluorophenoxy)methyl)-3-ethyl-6-(pi...) Show SMILES CCn1c(COc2cc(F)ccc2Cl)nc(cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H20ClFN4O2/c1-2-23-16(11-25-14-9-12(19)3-4-13(14)18)21-15(10-17(23)24)22-7-5-20-6-8-22/h3-4,9-10,20H,2,5-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	103	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301777 (3-(3-(2-chlorophenoxy)propyl)-6-methyl-2-(piperazi...) Show SMILES Cc1cc(=O)n(CCCOc2ccccc2Cl)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H23ClN4O2/c1-14-13-17(24)23(18(21-14)22-10-7-20-8-11-22)9-4-12-25-16-6-3-2-5-15(16)19/h2-3,5-6,13,20H,4,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301776 (3-(3-(4-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) Show SMILES Cc1cc(=O)n(CCCOc2ccc(F)cc2)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H23FN4O2/c1-14-13-17(24)23(18(21-14)22-10-7-20-8-11-22)9-2-12-25-16-5-3-15(19)4-6-16/h3-6,13,20H,2,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301775 (3-(3-(3-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) Show SMILES Cc1cc(=O)n(CCCOc2cccc(F)c2)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H23FN4O2/c1-14-12-17(24)23(18(21-14)22-9-6-20-7-10-22)8-3-11-25-16-5-2-4-15(19)13-16/h2,4-5,12-13,20H,3,6-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301774 (3-(3-(2-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) Show SMILES Cc1cc(=O)n(CCCOc2ccccc2F)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H23FN4O2/c1-14-13-17(24)23(18(21-14)22-10-7-20-8-11-22)9-4-12-25-16-6-3-2-5-15(16)19/h2-3,5-6,13,20H,4,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301773 (6-methyl-3-(3-phenoxypropyl)-2-(piperazin-1-yl)pyr...) Show SMILES Cc1cc(=O)n(CCCOc2ccccc2)c(n1)N1CCNCC1 Show InChI InChI=1S/C18H24N4O2/c1-15-14-17(23)22(18(20-15)21-11-8-19-9-12-21)10-5-13-24-16-6-3-2-4-7-16/h2-4,6-7,14,19H,5,8-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301772 ((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...) Show SMILES C[C@@H]1CNCCN1c1ccc(=O)n(CCOc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H21F3N4O2/c1-13-12-22-8-9-24(13)16-6-7-17(26)25(23-16)10-11-27-15-5-3-2-4-14(15)18(19,20)21/h2-7,13,22H,8-12H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301771 (6-(3-chlorophenethyl)-3-methyl-2-(piperazin-1-yl)p...) Show SMILES Cn1c(nc(CCc2cccc(Cl)c2)cc1=O)N1CCNCC1 Show InChI InChI=1S/C17H21ClN4O/c1-21-16(23)12-15(6-5-13-3-2-4-14(18)11-13)20-17(21)22-9-7-19-8-10-22/h2-4,11-12,19H,5-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(COc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H21F3N4O2/c1-12-10-22-7-8-25(12)15-9-17(26)24(2)16(23-15)11-27-14-6-4-3-5-13(14)18(19,20)21/h3-6,9,12,22H,7-8,10-11H2,1-2H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) Show SMILES C[C@@H]1CNCCN1c1cc(=O)n(C)c(COc2ccccc2C(F)(F)F)n1 |r| Show InChI InChI=1S/C18H21F3N4O2/c1-12-10-22-7-8-25(12)15-9-17(26)24(2)16(23-15)11-27-14-6-4-3-5-13(14)18(19,20)21/h3-6,9,12,22H,7-8,10-11H2,1-2H3/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.50E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2A receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3
					More data for this Ligand-Target Pair

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