Compile Data Set for Download or QSAR

Found 491 hits with Last Name = 'hipskind' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075807 (1-(3-{1-[2-(4-Iodo-phenyl)-ethyl]-piperidin-4-yl}-...) Show SMILES Ic1ccc(CCN2CCC(CCCn3c(COc4ccccc4)nc4c(OCCCN5CCCCC5)cccc34)CC2)cc1 Show InChI InChI=1S/C38H49IN4O2/c39-33-17-15-32(16-18-33)21-28-42-26-19-31(20-27-42)10-8-25-43-35-13-7-14-36(44-29-9-24-41-22-5-2-6-23-41)38(35)40-37(43)30-45-34-11-3-1-4-12-34/h1,3-4,7,11-18,31H,2,5-6,8-10,19-30H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075796 (2-Phenoxymethyl-4-(3-piperidin-1-yl-propoxy)-1-{3-...) Show SMILES C(COc1cccc2n(CCCC3CCN(CCCN4CCCCC4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C38H57N5O2/c1-4-15-34(16-5-1)45-32-37-39-38-35(17-10-18-36(38)44-31-13-27-41-23-8-3-9-24-41)43(37)28-11-14-33-19-29-42(30-20-33)26-12-25-40-21-6-2-7-22-40/h1,4-5,10,15-18,33H,2-3,6-9,11-14,19-32H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075811 (3-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-propo...) Show SMILES O=C(CCN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1)c1ccccc1 Show InChI InChI=1S/C39H50N4O3/c44-36(33-14-4-1-5-15-33)22-29-42-27-20-32(21-28-42)13-11-26-43-35-18-10-19-37(45-30-12-25-41-23-8-3-9-24-41)39(35)40-38(43)31-46-34-16-6-2-7-17-34/h1-2,4-7,10,14-19,32H,3,8-9,11-13,20-31H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075803 (4-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-propo...) Show SMILES O=C(CCCN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1)c1ccccc1 Show InChI InChI=1S/C40H52N4O3/c45-37(34-15-4-1-5-16-34)20-12-26-43-29-22-33(23-30-43)14-11-28-44-36-19-10-21-38(46-31-13-27-42-24-8-3-9-25-42)40(36)41-39(44)32-47-35-17-6-2-7-18-35/h1-2,4-7,10,15-19,21,33H,3,8-9,11-14,20,22-32H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186291 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...) Show SMILES CC(C)N1CCc2ccc(OCCCN3CCCCC3)cc2C1 Show InChI InChI=1S/C20H32N2O/c1-17(2)22-13-9-18-7-8-20(15-19(18)16-22)23-14-6-12-21-10-4-3-5-11-21/h7-8,15,17H,3-6,9-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075812 (2-Phenoxymethyl-1-{3-[1-((Z)-3-phenyl-allyl)-piper...) Show SMILES C(COc1cccc2n(CCCC3CCN(C\C=C/c4ccccc4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C39H50N4O2/c1-4-14-33(15-5-1)16-11-26-42-29-22-34(23-30-42)17-12-28-43-36-20-10-21-37(44-31-13-27-41-24-8-3-9-25-41)39(36)40-38(43)32-45-35-18-6-2-7-19-35/h1-2,4-7,10-11,14-16,18-21,34H,3,8-9,12-13,17,22-32H2/b16-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075809 (1-[3-(1-Phenethyl-piperidin-4-yl)-propyl]-2-phenox...) Show SMILES C(COc1cccc2n(CCCC3CCN(CCc4ccccc4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C38H50N4O2/c1-4-13-32(14-5-1)20-27-41-28-21-33(22-29-41)15-11-26-42-35-18-10-19-36(43-30-12-25-40-23-8-3-9-24-40)38(35)39-37(42)31-44-34-16-6-2-7-17-34/h1-2,4-7,10,13-14,16-19,33H,3,8-9,11-12,15,20-31H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186270 (2-benzyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tet...) Show SMILES C(COc1ccc2CN(Cc3ccccc3)CCCc2c1)CN1CCCCC1 Show InChI InChI=1S/C25H34N2O/c1-3-9-22(10-4-1)20-27-16-7-11-23-19-25(13-12-24(23)21-27)28-18-8-17-26-14-5-2-6-15-26/h1,3-4,9-10,12-13,19H,2,5-8,11,14-18,20-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186278 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...) Show SMILES CC(C)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186290 (3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075797 (1-{3-[1-(2-Cyclohexyl-ethyl)-piperidin-4-yl]-propy...) Show SMILES C(COc1cccc2n(CCCC3CCN(CCC4CCCCC4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C38H56N4O2/c1-4-13-32(14-5-1)20-27-41-28-21-33(22-29-41)15-11-26-42-35-18-10-19-36(43-30-12-25-40-23-8-3-9-24-40)38(35)39-37(42)31-44-34-16-6-2-7-17-34/h2,6-7,10,16-19,32-33H,1,3-5,8-9,11-15,20-31H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075806 (1-{3-[1-(3-Methyl-butyl)-piperidin-4-yl]-propyl}-2...) Show SMILES CC(C)CCN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C35H52N4O2/c1-29(2)17-24-38-25-18-30(19-26-38)12-10-23-39-32-15-9-16-33(40-27-11-22-37-20-7-4-8-21-37)35(32)36-34(39)28-41-31-13-5-3-6-14-31/h3,5-6,9,13-16,29-30H,4,7-8,10-12,17-28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075802 (4-[2-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-pr...) Show SMILES Oc1ccc(CCN2CCC(CCCn3c(COc4ccccc4)nc4c(OCCCN5CCCCC5)cccc34)CC2)cc1 Show InChI InChI=1S/C38H50N4O3/c43-33-17-15-32(16-18-33)21-28-41-26-19-31(20-27-41)10-8-25-42-35-13-7-14-36(44-29-9-24-40-22-5-2-6-23-40)38(35)39-37(42)30-45-34-11-3-1-4-12-34/h1,3-4,7,11-18,31,43H,2,5-6,8-10,19-30H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.313	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186309 (2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186269 (2-ethyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2C1 Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-7-8-19(15-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186292 (2-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...) Show SMILES C(COc1ccc2CCN(CC3CCCCC3)Cc2c1)CN1CCCCC1 Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-10-11-24(18-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075799 (2-Phenoxymethyl-1-{3-[1-(3-phenyl-propyl)-piperidi...) Show SMILES C(COc1cccc2n(CCCC3CCN(CCCc4ccccc4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C39H52N4O2/c1-4-14-33(15-5-1)16-11-26-42-29-22-34(23-30-42)17-12-28-43-36-20-10-21-37(44-31-13-27-41-24-8-3-9-25-41)39(36)40-38(43)32-45-35-18-6-2-7-19-35/h1-2,4-7,10,14-15,18-21,34H,3,8-9,11-13,16-17,22-32H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075798 (1-[3-(1-Cyclohexylmethyl-piperidin-4-yl)-propyl]-2...) Show SMILES C(COc1cccc2n(CCCC3CCN(CC4CCCCC4)CC3)c(COc3ccccc3)nc12)CN1CCCCC1 Show InChI InChI=1S/C37H54N4O2/c1-4-13-32(14-5-1)29-40-26-20-31(21-27-40)15-11-25-41-34-18-10-19-35(42-28-12-24-39-22-8-3-9-23-39)37(34)38-36(41)30-43-33-16-6-2-7-17-33/h2,6-7,10,16-19,31-32H,1,3-5,8-9,11-15,20-30H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186292 (2-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...) Show SMILES C(COc1ccc2CCN(CC3CCCCC3)Cc2c1)CN1CCCCC1 Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-10-11-24(18-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186316 (2-(phenylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-1...) Show SMILES O=S(=O)(N1CCc2ccc(OCCCN3CCCCC3)cc2C1)c1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c26-29(27,23-8-3-1-4-9-23)25-16-12-20-10-11-22(18-21(20)19-25)28-17-7-15-24-13-5-2-6-14-24/h1,3-4,8-11,18H,2,5-7,12-17,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186306 (3-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...) Show SMILES C(COc1ccc2CCN(CC3CCCCC3)CCc2c1)CN1CCCCC1 Show InChI InChI=1S/C25H40N2O/c1-3-8-22(9-4-1)21-27-17-12-23-10-11-25(20-24(23)13-18-27)28-19-7-16-26-14-5-2-6-15-26/h10-11,20,22H,1-9,12-19,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186283 (2-ethyl-6-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...) Show SMILES CCN1CCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-15-19(8-7-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186309 (2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186293 (7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydrois...) Show SMILES C(COc1ccc2CCNCc2c1)CN1CCCCC1 Show InChI InChI=1S/C17H26N2O/c1-2-9-19(10-3-1)11-4-12-20-17-6-5-15-7-8-18-14-16(15)13-17/h5-6,13,18H,1-4,7-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186269 (2-ethyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2C1 Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-7-8-19(15-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075795 (1-[3-(1-But-3-enyl-piperidin-4-yl)-propyl]-2-pheno...) Show SMILES C=CCCN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C34H48N4O2/c1-2-3-20-37-25-18-29(19-26-37)13-11-24-38-31-16-10-17-32(39-27-12-23-36-21-8-5-9-22-36)34(31)35-33(38)28-40-30-14-6-4-7-15-30/h2,4,6-7,10,14-17,29H,1,3,5,8-9,11-13,18-28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.707	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186311 (3-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...) Show SMILES CC(C)N1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-9-19-7-8-21(17-20(19)10-15-23)24-16-6-13-22-11-4-3-5-12-22/h7-8,17-18H,3-6,9-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075808 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCCC2CCCNC2)cc1 Show InChI InChI=1S/C35H47ClN4O2/c36-28-12-14-30(15-13-28)42-26-33-35(34(41)25-38-22-16-29(17-23-38)39-19-4-1-5-20-39)31-10-2-3-11-32(31)40(33)21-7-9-27-8-6-18-37-24-27/h2-3,10-15,27,29,37H,1,4-9,16-26H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060725 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC[C@@H]2CCCNC2)cc1 Show InChI InChI=1S/C35H47ClN4O2/c36-28-12-14-30(15-13-28)42-26-33-35(34(41)25-38-22-16-29(17-23-38)39-19-4-1-5-20-39)31-10-2-3-11-32(31)40(33)21-7-9-27-8-6-18-37-24-27/h2-3,10-15,27,29,37H,1,4-9,16-26H2/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060725 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC[C@@H]2CCCNC2)cc1 Show InChI InChI=1S/C35H47ClN4O2/c36-28-12-14-30(15-13-28)42-26-33-35(34(41)25-38-22-16-29(17-23-38)39-19-4-1-5-20-39)31-10-2-3-11-32(31)40(33)21-7-9-27-8-6-18-37-24-27/h2-3,10-15,27,29,37H,1,4-9,16-26H2/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YY				J Med Chem 41: 2709-19 (1998) Article DOI: 10.1021/jm9706630 BindingDB Entry DOI: 10.7270/Q2TD9WGN
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186270 (2-benzyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tet...) Show SMILES C(COc1ccc2CN(Cc3ccccc3)CCCc2c1)CN1CCCCC1 Show InChI InChI=1S/C25H34N2O/c1-3-9-22(10-4-1)20-27-16-7-11-23-19-25(13-12-24(23)21-27)28-18-8-17-26-14-5-2-6-15-26/h1,3-4,9-10,12-13,19H,2,5-8,11,14-18,20-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075804 (1-[3-(1-Isobutyl-piperidin-4-yl)-propyl]-2-phenoxy...) Show SMILES CC(C)CN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C34H50N4O2/c1-28(2)26-37-23-17-29(18-24-37)12-10-22-38-31-15-9-16-32(39-25-11-21-36-19-7-4-8-20-36)34(31)35-33(38)27-40-30-13-5-3-6-14-30/h3,5-6,9,13-16,28-29H,4,7-8,10-12,17-27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.829	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186291 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...) Show SMILES CC(C)N1CCc2ccc(OCCCN3CCCCC3)cc2C1 Show InChI InChI=1S/C20H32N2O/c1-17(2)22-13-9-18-7-8-20(15-19(18)16-22)23-14-6-12-21-10-4-3-5-11-21/h7-8,15,17H,3-6,9-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186306 (3-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...) Show SMILES C(COc1ccc2CCN(CC3CCCCC3)CCc2c1)CN1CCCCC1 Show InChI InChI=1S/C25H40N2O/c1-3-8-22(9-4-1)21-27-17-12-23-10-11-25(20-24(23)13-18-27)28-19-7-16-26-14-5-2-6-15-26/h10-11,20,22H,1-9,12-19,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186296 (2-(cyclohexylmethyl)-6-(3-(piperidin-1-yl)propoxy)...) Show SMILES C(COc1ccc2CN(CC3CCCCC3)CCc2c1)CN1CCCCC1 Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-18-24(11-10-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186290 (3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186278 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...) Show SMILES CC(C)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060726 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC[C@H]2CCCNC2)cc1 Show InChI InChI=1S/C35H47ClN4O2/c36-28-12-14-30(15-13-28)42-26-33-35(34(41)25-38-22-16-29(17-23-38)39-19-4-1-5-20-39)31-10-2-3-11-32(31)40(33)21-7-9-27-8-6-18-37-24-27/h2-3,10-15,27,29,37H,1,4-9,16-26H2/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186311 (3-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...) Show SMILES CC(C)N1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-9-19-7-8-21(17-20(19)10-15-23)24-16-6-13-22-11-4-3-5-12-22/h7-8,17-18H,3-6,9-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075810 (1-[3-(1-Isopropyl-piperidin-4-yl)-propyl]-2-phenox...) Show SMILES CC(C)N1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C33H48N4O2/c1-27(2)36-23-17-28(18-24-36)12-10-22-37-30-15-9-16-31(38-25-11-21-35-19-7-4-8-20-35)33(30)34-32(37)26-39-29-13-5-3-6-14-29/h3,5-6,9,13-16,27-28H,4,7-8,10-12,17-26H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075800 (1-[3-(1-Allyl-piperidin-4-yl)-propyl]-2-phenoxymet...) Show SMILES C=CCN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C33H46N4O2/c1-2-19-35-24-17-28(18-25-35)12-10-23-37-30-15-9-16-31(38-26-11-22-36-20-7-4-8-21-36)33(30)34-32(37)27-39-29-13-5-3-6-14-29/h2-3,5-6,9,13-16,28H,1,4,7-8,10-12,17-27H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50075801 (1-[3-(1-Methyl-piperidin-4-yl)-propyl]-2-phenoxyme...) Show SMILES CN1CCC(CCCn2c(COc3ccccc3)nc3c(OCCCN4CCCCC4)cccc23)CC1 Show InChI InChI=1S/C31H44N4O2/c1-33-22-16-26(17-23-33)11-9-21-35-28-14-8-15-29(36-24-10-20-34-18-6-3-7-19-34)31(28)32-30(35)25-37-27-12-4-2-5-13-27/h2,4-5,8,12-15,26H,3,6-7,9-11,16-25H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50065468 (2-(4-Chloro-phenoxymethyl)-4-(3-piperidin-1-yl-pro...) Show SMILES Clc1ccc(OCc2nc3c(OCCCN4CCCCC4)cccc3n2CCCC2CCCNC2)cc1 Show InChI InChI=1S/C30H41ClN4O2/c31-25-12-14-26(15-13-25)37-23-29-33-30-27(35(29)20-6-9-24-8-5-16-32-22-24)10-4-11-28(30)36-21-7-19-34-17-2-1-3-18-34/h4,10-15,24,32H,1-3,5-9,16-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50065468 (2-(4-Chloro-phenoxymethyl)-4-(3-piperidin-1-yl-pro...) Show SMILES Clc1ccc(OCc2nc3c(OCCCN4CCCCC4)cccc3n2CCCC2CCCNC2)cc1 Show InChI InChI=1S/C30H41ClN4O2/c31-25-12-14-26(15-13-25)37-23-29-33-30-27(35(29)20-6-9-24-8-5-16-32-22-24)10-4-11-28(30)36-21-7-19-34-17-2-1-3-18-34/h4,10-15,24,32H,1-3,5-9,16-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YY				J Med Chem 41: 2709-19 (1998) Article DOI: 10.1021/jm9706630 BindingDB Entry DOI: 10.7270/Q2TD9WGN
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060725 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC[C@@H]2CCCNC2)cc1 Show InChI InChI=1S/C35H47ClN4O2/c36-28-12-14-30(15-13-28)42-26-33-35(34(41)25-38-22-16-29(17-23-38)39-19-4-1-5-20-39)31-10-2-3-11-32(31)40(33)21-7-9-27-8-6-18-37-24-27/h2-3,10-15,27,29,37H,1,4-9,16-26H2/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability of the compound to reverse Neuropeptide Y receptor type 1-induced inhibition of forskolin-induced inhibition of forskolin-stimulated cAMP				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060724 (2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...) Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC2CCNCC2)cc1 Show InChI InChI=1S/C34H45ClN4O2/c35-27-8-10-29(11-9-27)41-25-32-34(33(40)24-37-21-15-28(16-22-37)38-19-4-1-5-20-38)30-6-2-3-7-31(30)39(32)23-14-26-12-17-36-18-13-26/h2-3,6-11,26,28,36H,1,4-5,12-25H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50065468 (2-(4-Chloro-phenoxymethyl)-4-(3-piperidin-1-yl-pro...) Show SMILES Clc1ccc(OCc2nc3c(OCCCN4CCCCC4)cccc3n2CCCC2CCCNC2)cc1 Show InChI InChI=1S/C30H41ClN4O2/c31-25-12-14-26(15-13-25)37-23-29-33-30-27(35(29)20-6-9-24-8-5-16-32-22-24)10-4-11-28(30)36-21-7-19-34-17-2-1-3-18-34/h4,10-15,24,32H,1-3,5-9,16-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Binding affinity of the compound at cloned Neuropeptide Y receptor type 1 expressed in AV-12 cells is evaluated.				Bioorg Med Chem Lett 8: 473-6 (1999) BindingDB Entry DOI: 10.7270/Q2GH9H33
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186281 ((6-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoquino...) Show SMILES O=C(N1CCc2cc(OCCCN3CCCCC3)ccc2C1)c1cccs1 Show InChI InChI=1S/C22H28N2O2S/c25-22(21-6-4-15-27-21)24-13-9-18-16-20(8-7-19(18)17-24)26-14-5-12-23-10-2-1-3-11-23/h4,6-8,15-16H,1-3,5,9-14,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186295 (2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2...) Show SMILES CS(=O)(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1 Show InChI InChI=1S/C19H30N2O3S/c1-25(22,23)21-13-5-7-17-15-19(9-8-18(17)16-21)24-14-6-12-20-10-3-2-4-11-20/h8-9,15H,2-7,10-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50069414 (2-(4-Chloro-phenoxymethyl)-4-methyl-1-{3-[1-(3-pip...) Show SMILES Cc1cccc2n(CCCC3CCN(CCCN4CCCCC4)CC3)c(COc3ccc(Cl)cc3)nc12 Show InChI InChI=1S/C31H43ClN4O/c1-25-8-5-10-29-31(25)33-30(24-37-28-13-11-27(32)12-14-28)36(29)21-6-9-26-15-22-35(23-16-26)20-7-19-34-17-3-2-4-18-34/h5,8,10-14,26H,2-4,6-7,9,15-24H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cells				Bioorg Med Chem Lett 9: 647-52 (1999) BindingDB Entry DOI: 10.7270/Q2QN65ZK
					More data for this Ligand-Target Pair

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