Compile Data Set for Download or QSAR

Found 39 hits with Last Name = 'jalota-badhwar' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50008935 ((20S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy...) Show SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O |r| Show InChI InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329895 (2-chloro-N-(6-(4-hydroxy-6-(trifluoromethyl)pyrimi...) Show SMILES FC(F)(F)c1cc(=O)[nH]c(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H8ClF3N4O2/c13-4-10(22)18-6-1-2-7(17-5-6)11-19-8(12(14,15)16)3-9(21)20-11/h1-3,5H,4H2,(H,18,22)(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329898 (2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimid...) Show SMILES FC(F)(F)c1cc(Cl)nc(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H7Cl2F3N4O/c13-4-10(22)19-6-1-2-7(18-5-6)11-20-8(12(15,16)17)3-9(14)21-11/h1-3,5H,4H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329896 (CHEMBL1271980 | N-(6-(4-(allyloxy)-5-chloro-6-meth...) Show SMILES Cc1nc(nc(OCC=C)c1Cl)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-3-6-23-15-13(17)9(2)19-14(21-15)11-5-4-10(8-18-11)20-12(22)7-16/h3-5,8H,1,6-7H2,2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329891 (2-chloro-N-(6-(5-ethyl-4-hydroxy-6-methylpyrimidin...) Show SMILES CCc1c(C)nc([nH]c1=O)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C14H15ClN4O2/c1-3-10-8(2)17-13(19-14(10)21)11-5-4-9(7-16-11)18-12(20)6-15/h4-5,7H,3,6H2,1-2H3,(H,18,20)(H,17,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329892 (2-chloro-N-(6-(4-(chloromethyl)-6-hydroxypyrimidin...) Show SMILES ClCC(=O)Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1 Show InChI InChI=1S/C12H10Cl2N4O2/c13-4-8-3-10(19)18-12(17-8)9-2-1-7(6-15-9)16-11(20)5-14/h1-3,6H,4-5H2,(H,16,20)(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329899 (CHEMBL1271924 | N-(6-(4-(allyloxy)-5-ethyl-6-methy...) Show SMILES CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C17H19ClN4O2/c1-4-8-24-17-13(5-2)11(3)20-16(22-17)14-7-6-12(10-19-14)21-15(23)9-18/h4,6-7,10H,1,5,8-9H2,2-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329887 (CHEMBL1271978 | N-(6-(4-(allyloxy)-6-(trifluoromet...) Show SMILES FC(F)(F)c1cc(OCC=C)nc(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H12ClF3N4O2/c1-2-5-25-13-6-11(15(17,18)19)22-14(23-13)10-4-3-9(8-20-10)21-12(24)7-16/h2-4,6,8H,1,5,7H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329894 (2-chloro-N-(6-(5-fluoro-4-hydroxy-6-methylpyrimidi...) Show SMILES Cc1nc([nH]c(=O)c1F)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H10ClFN4O2/c1-6-10(14)12(20)18-11(16-6)8-3-2-7(5-15-8)17-9(19)4-13/h2-3,5H,4H2,1H3,(H,17,19)(H,16,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50008935 ((20S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy...) Show SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O |r| Show InChI InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329888 (2-chloro-N-(6-(4-methoxy-6-(trifluoromethyl)pyrimi...) Show SMILES COc1cc(nc(n1)-c1ccc(NC(=O)CCl)cn1)C(F)(F)F Show InChI InChI=1S/C13H10ClF3N4O2/c1-23-11-4-9(13(15,16)17)20-12(21-11)8-3-2-7(6-18-8)19-10(22)5-14/h2-4,6H,5H2,1H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329889 (CHEMBL1271868 | N-(6-(5-benzyl-4-hydroxy-6-methylp...) Show SMILES Cc1nc([nH]c(=O)c1Cc1ccccc1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C19H17ClN4O2/c1-12-15(9-13-5-3-2-4-6-13)19(26)24-18(22-12)16-8-7-14(11-21-16)23-17(25)10-20/h2-8,11H,9-10H2,1H3,(H,23,25)(H,22,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329892 (2-chloro-N-(6-(4-(chloromethyl)-6-hydroxypyrimidin...) Show SMILES ClCC(=O)Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1 Show InChI InChI=1S/C12H10Cl2N4O2/c13-4-8-3-10(19)18-12(17-8)9-2-1-7(6-15-9)16-11(20)5-14/h1-3,6H,4-5H2,(H,16,20)(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329891 (2-chloro-N-(6-(5-ethyl-4-hydroxy-6-methylpyrimidin...) Show SMILES CCc1c(C)nc([nH]c1=O)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C14H15ClN4O2/c1-3-10-8(2)17-13(19-14(10)21)11-5-4-9(7-16-11)18-12(20)6-15/h4-5,7H,3,6H2,1-2H3,(H,18,20)(H,17,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329890 (2-chloro-N-(6-(5-chloro-4-hydroxy-6-methylpyrimidi...) Show SMILES Cc1nc([nH]c(=O)c1Cl)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H10Cl2N4O2/c1-6-10(14)12(20)18-11(16-6)8-3-2-7(5-15-8)17-9(19)4-13/h2-3,5H,4H2,1H3,(H,17,19)(H,16,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329893 (2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-...) Show SMILES Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1 Show InChI InChI=1S/C10H9ClN4O/c11-4-7-3-9(16)15-10(14-7)8-2-1-6(12)5-13-8/h1-3,5H,4,12H2,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329894 (2-chloro-N-(6-(5-fluoro-4-hydroxy-6-methylpyrimidi...) Show SMILES Cc1nc([nH]c(=O)c1F)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H10ClFN4O2/c1-6-10(14)12(20)18-11(16-6)8-3-2-7(5-15-8)17-9(19)4-13/h2-3,5H,4H2,1H3,(H,17,19)(H,16,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329896 (CHEMBL1271980 | N-(6-(4-(allyloxy)-5-chloro-6-meth...) Show SMILES Cc1nc(nc(OCC=C)c1Cl)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-3-6-23-15-13(17)9(2)19-14(21-15)11-5-4-10(8-18-11)20-12(22)7-16/h3-5,8H,1,6-7H2,2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329897 (2-chloro-N-(6-(4-ethoxy-6-(trifluoromethyl)pyrimid...) Show SMILES CCOc1cc(nc(n1)-c1ccc(NC(=O)CCl)cn1)C(F)(F)F Show InChI InChI=1S/C14H12ClF3N4O2/c1-2-24-12-5-10(14(16,17)18)21-13(22-12)9-4-3-8(7-19-9)20-11(23)6-15/h3-5,7H,2,6H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329895 (2-chloro-N-(6-(4-hydroxy-6-(trifluoromethyl)pyrimi...) Show SMILES FC(F)(F)c1cc(=O)[nH]c(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H8ClF3N4O2/c13-4-10(22)18-6-1-2-7(17-5-6)11-19-8(12(14,15)16)3-9(21)20-11/h1-3,5H,4H2,(H,18,22)(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329889 (CHEMBL1271868 | N-(6-(5-benzyl-4-hydroxy-6-methylp...) Show SMILES Cc1nc([nH]c(=O)c1Cc1ccccc1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C19H17ClN4O2/c1-12-15(9-13-5-3-2-4-6-13)19(26)24-18(22-12)16-8-7-14(11-21-16)23-17(25)10-20/h2-8,11H,9-10H2,1H3,(H,23,25)(H,22,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329898 (2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimid...) Show SMILES FC(F)(F)c1cc(Cl)nc(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C12H7Cl2F3N4O/c13-4-10(22)19-6-1-2-7(18-5-6)11-20-8(12(15,16)17)3-9(14)21-11/h1-3,5H,4H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329888 (2-chloro-N-(6-(4-methoxy-6-(trifluoromethyl)pyrimi...) Show SMILES COc1cc(nc(n1)-c1ccc(NC(=O)CCl)cn1)C(F)(F)F Show InChI InChI=1S/C13H10ClF3N4O2/c1-23-11-4-9(13(15,16)17)20-12(21-11)8-3-2-7(6-18-8)19-10(22)5-14/h2-4,6H,5H2,1H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329893 (2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-...) Show SMILES Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1 Show InChI InChI=1S/C10H9ClN4O/c11-4-7-3-9(16)15-10(14-7)8-2-1-6(12)5-13-8/h1-3,5H,4,12H2,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329899 (CHEMBL1271924 | N-(6-(4-(allyloxy)-5-ethyl-6-methy...) Show SMILES CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C17H19ClN4O2/c1-4-8-24-17-13(5-2)11(3)20-16(22-17)14-7-6-12(10-19-14)21-15(23)9-18/h4,6-7,10H,1,5,8-9H2,2-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329910 (6-(4-methoxy-6-(trifluoromethyl)pyrimidin-2-yl)pyr...) Show SMILES COc1cc(nc(n1)-c1ccc(N)cn1)C(F)(F)F Show InChI InChI=1S/C11H9F3N4O/c1-19-9-4-8(11(12,13)14)17-10(18-9)7-3-2-6(15)5-16-7/h2-5H,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329909 (6-(4-(allyloxy)-6-(trifluoromethyl)pyrimidin-2-yl)...) Show SMILES Nc1ccc(nc1)-c1nc(OCC=C)cc(n1)C(F)(F)F Show InChI InChI=1S/C13H11F3N4O/c1-2-5-21-11-6-10(13(14,15)16)19-12(20-11)9-4-3-8(17)7-18-9/h2-4,6-7H,1,5,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329912 (6-(4-ethoxy-6-(trifluoromethyl)pyrimidin-2-yl)pyri...) Show SMILES CCOc1cc(nc(n1)-c1ccc(N)cn1)C(F)(F)F Show InChI InChI=1S/C12H11F3N4O/c1-2-20-10-5-9(12(13,14)15)18-11(19-10)8-4-3-7(16)6-17-8/h3-6H,2,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329908 (6-(4-(allyloxy)-5-ethyl-6-methylpyrimidin-2-yl)pyr...) Show SMILES CCc1c(C)nc(nc1OCC=C)-c1ccc(N)cn1 Show InChI InChI=1S/C15H18N4O/c1-4-8-20-15-12(5-2)10(3)18-14(19-15)13-7-6-11(16)9-17-13/h4,6-7,9H,1,5,8,16H2,2-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329907 (2-chloro-2,2-difluoro-N-(6-(4-hydroxy-6-(trifluoro...) Show SMILES FC(F)(F)c1cc(=O)[nH]c(n1)-c1ccc(NC(=O)C(F)(F)Cl)cn1 Show InChI InChI=1S/C12H6ClF5N4O2/c13-11(14,15)10(24)20-5-1-2-6(19-4-5)9-21-7(12(16,17)18)3-8(23)22-9/h1-4H,(H,20,24)(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329906 (2-chloro-N-(6-(4-hydroxy-5,6-dimethylpyrimidin-2-y...) Show SMILES Cc1nc([nH]c(=O)c1C)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C13H13ClN4O2/c1-7-8(2)16-12(18-13(7)20)10-4-3-9(6-15-10)17-11(19)5-14/h3-4,6H,5H2,1-2H3,(H,17,19)(H,16,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329905 (2-(5-aminopyridin-2-yl)-5-fluoro-6-methylpyrimidin...) Show SMILES Cc1nc([nH]c(=O)c1F)-c1ccc(N)cn1 Show InChI InChI=1S/C10H9FN4O/c1-5-8(11)10(16)15-9(14-5)7-3-2-6(12)4-13-7/h2-4H,12H2,1H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329904 (2-(5-aminopyridin-2-yl)-5-benzyl-6-methylpyrimidin...) Show SMILES Cc1nc([nH]c(=O)c1Cc1ccccc1)-c1ccc(N)cn1 Show InChI InChI=1S/C17H16N4O/c1-11-14(9-12-5-3-2-4-6-12)17(22)21-16(20-11)15-8-7-13(18)10-19-15/h2-8,10H,9,18H2,1H3,(H,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329903 (2-(5-aminopyridin-2-yl)-5-ethyl-6-methylpyrimidin-...) Show SMILES CCc1c(C)nc([nH]c1=O)-c1ccc(N)cn1 Show InChI InChI=1S/C12H14N4O/c1-3-9-7(2)15-11(16-12(9)17)10-5-4-8(13)6-14-10/h4-6H,3,13H2,1-2H3,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329902 (2-(5-aminopyridin-2-yl)-5,6-dimethylpyrimidin-4-ol...) Show SMILES Cc1nc([nH]c(=O)c1C)-c1ccc(N)cn1 Show InChI InChI=1S/C11H12N4O/c1-6-7(2)14-10(15-11(6)16)9-4-3-8(12)5-13-9/h3-5H,12H2,1-2H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329911 (6-(4-(allyloxy)-5-chloro-6-methylpyrimidin-2-yl)py...) Show SMILES Cc1nc(nc(OCC=C)c1Cl)-c1ccc(N)cn1 Show InChI InChI=1S/C13H13ClN4O/c1-3-6-19-13-11(14)8(2)17-12(18-13)10-5-4-9(15)7-16-10/h3-5,7H,1,6,15H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329900 (2-(5-aminopyridin-2-yl)-6-(trifluoromethyl)pyrimid...) Show SMILES Nc1ccc(nc1)-c1nc(cc(=O)[nH]1)C(F)(F)F Show InChI InChI=1S/C10H7F3N4O/c11-10(12,13)7-3-8(18)17-9(16-7)6-2-1-5(14)4-15-6/h1-4H,14H2,(H,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329887 (CHEMBL1271978 | N-(6-(4-(allyloxy)-6-(trifluoromet...) Show SMILES FC(F)(F)c1cc(OCC=C)nc(n1)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C15H12ClF3N4O2/c1-2-5-25-13-6-11(15(17,18)19)22-14(23-13)10-4-3-9(8-20-10)21-12(24)7-16/h2-4,6,8H,1,5,7H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329901 (2-(5-aminopyridin-2-yl)-5-chloro-6-methylpyrimidin...) Show SMILES Cc1nc([nH]c(=O)c1Cl)-c1ccc(N)cn1 Show InChI InChI=1S/C10H9ClN4O/c1-5-8(11)10(16)15-9(14-5)7-3-2-6(12)4-13-7/h2-4H,12H2,1H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair