Compile Data Set for Download or QSAR

Found 211 hits with Last Name = 'mercè' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163035 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12 Show InChI InChI=1S/C21H22ClN3O2S2/c1-13-17-10-15(22)4-7-20(17)28-21(13)29(26,27)24-16-5-6-19-18(11-16)14(12-23-19)8-9-25(2)3/h4-7,10-12,23-24H,8-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34143 (CHEMBL175835 | E-6837) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12 Show InChI InChI=1S/C22H22ClN3O2S/c1-26(2)11-10-16-14-24-22-9-6-17(13-20(16)22)25-29(27,28)18-7-8-19-15(12-18)4-3-5-21(19)23/h3-9,12-14,24-25H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163094 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12 Show InChI InChI=1S/C23H26ClN3O2S2/c1-4-27(5-2)11-10-16-14-25-21-8-7-18(13-20(16)21)26-31(28,29)23-15(3)19-12-17(24)6-9-22(19)30-23/h6-9,12-14,25-26H,4-5,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163067 (Biphenyl-4-sulfonic acid [3-(2-dimethylamino-ethyl...) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cc12 Show InChI InChI=1S/C24H25N3O2S/c1-27(2)15-14-20-17-25-24-13-10-21(16-23(20)24)26-30(28,29)22-11-8-19(9-12-22)18-6-4-3-5-7-18/h3-13,16-17,25-26H,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34145 (pyrrolidinylindole, (R)-5b) Show SMILES [H][C@]1(Cc2c[nH]c3ccc(NS(=O)(=O)c4ccc(cc4)C(F)(F)F)cc23)CCCN1C |r| Show InChI InChI=1S/C21H22F3N3O2S/c1-27-10-2-3-17(27)11-14-13-25-20-9-6-16(12-19(14)20)26-30(28,29)18-7-4-15(5-8-18)21(22,23)24/h4-9,12-13,17,25-26H,2-3,10-11H2,1H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.400	-55.8	n/a	n/a	4.5	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163061 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES CCCN(CCC)CCc1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12 Show InChI InChI=1S/C25H30ClN3O2S2/c1-4-11-29(12-5-2)13-10-18-16-27-23-8-7-20(15-22(18)23)28-33(30,31)25-17(3)21-14-19(26)6-9-24(21)32-25/h6-9,14-16,27-28H,4-5,10-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34143 (CHEMBL175835 | E-6837) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12 Show InChI InChI=1S/C22H22ClN3O2S/c1-26(2)11-10-16-14-24-22-9-6-17(13-20(16)22)25-29(27,28)18-7-8-19-15(12-18)4-3-5-21(19)23/h3-9,12-14,24-25H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	-54.4	n/a	n/a	0.290	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34143 (CHEMBL175835 | E-6837) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12 Show InChI InChI=1S/C22H22ClN3O2S/c1-26(2)11-10-16-14-24-22-9-6-17(13-20(16)22)25-29(27,28)18-7-8-19-15(12-18)4-3-5-21(19)23/h3-9,12-14,24-25H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
4SC AG Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6224-9 (2007) Article DOI: 10.1016/j.bmcl.2007.09.016 BindingDB Entry DOI: 10.7270/Q2D79B43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34143 (CHEMBL175835 | E-6837) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12 Show InChI InChI=1S/C22H22ClN3O2S/c1-26(2)11-10-16-14-24-22-9-6-17(13-20(16)22)25-29(27,28)18-7-8-19-15(12-18)4-3-5-21(19)23/h3-9,12-14,24-25H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163053 (CHEMBL368390 | Naphthalene-1-sulfonic acid [3-(2-d...) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C22H23N3O2S/c1-25(2)13-12-17-15-23-21-11-10-18(14-20(17)21)24-28(26,27)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14-15,23-24H,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28583 (5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...) Show SMILES COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1 Show InChI InChI=1S/C20H22ClN3O3S2/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24/h3-6,11-12,22-23H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34144 ((R)-5a | WAY-466) Show SMILES [H][C@]1(Cc2c[nH]c3ccc(NS(=O)(=O)c4ccccc4I)cc23)CCCN1 |r| Show InChI InChI=1S/C19H20IN3O2S/c20-17-5-1-2-6-19(17)26(24,25)23-15-7-8-18-16(11-15)13(12-22-18)10-14-4-3-9-21-14/h1-2,5-8,11-12,14,21-23H,3-4,9-10H2/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1	-53.4	n/a	n/a	0.400	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163071 (Biphenyl-4-sulfonic acid [3-(2-diethylamino-ethyl)...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cc12 Show InChI InChI=1S/C26H29N3O2S/c1-3-29(4-2)17-16-22-19-27-26-15-12-23(18-25(22)26)28-32(30,31)24-13-10-21(11-14-24)20-8-6-5-7-9-20/h5-15,18-19,27-28H,3-4,16-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34147 (CHEMBL425196 | pyrrolidinylindole, 6) Show SMILES CN1CCC(C1)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1Br Show InChI InChI=1S/C19H19BrN2O2S/c1-21-11-10-14(12-21)16-13-22(18-8-4-2-6-15(16)18)25(23,24)19-9-5-3-7-17(19)20/h2-9,13-14H,10-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	-53.4	n/a	n/a	53.3	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300675 (2-(1-(5-(phenylsulfonamido)-1H-indol-3-yl)ethylide...) Show SMILES CC(=NN=C(N)N)c1c[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc12 |w:2.2,(28.57,2.48,;29.6,1.34,;31.11,1.66,;31.59,3.12,;33.09,3.44,;33.57,4.91,;34.12,2.3,;29.13,-.13,;30.04,-1.38,;29.13,-2.64,;27.66,-2.16,;26.32,-2.93,;24.99,-2.16,;24.99,-.62,;23.66,.15,;23.65,1.69,;23.64,3.23,;24.97,1.68,;22.11,1.7,;21.36,3.04,;19.82,3.05,;19.04,1.72,;19.81,.38,;21.35,.38,;26.31,.15,;27.65,-.61,)| Show InChI InChI=1S/C17H18N6O2S/c1-11(21-22-17(18)19)15-10-20-16-8-7-12(9-14(15)16)23-26(24,25)13-5-3-2-4-6-13/h2-10,20,23H,1H3,(H4,18,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300676 (2-(1-(5-(4-methoxyphenylsulfonamido)-1H-indol-3-yl...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]cc(C(C)=NN=C(N)N)c2c1 |w:21.22,(-11.39,-8.91,;-10.64,-10.25,;-9.1,-10.26,;-8.32,-8.93,;-6.78,-8.93,;-6.03,-10.28,;-6.79,-11.6,;-8.33,-11.6,;-4.49,-10.28,;-4.5,-8.74,;-3.17,-10.29,;-4.49,-11.82,;-3.15,-12.59,;-3.15,-14.14,;-1.82,-14.91,;-.48,-14.14,;.99,-14.62,;1.9,-13.36,;.99,-12.1,;1.46,-10.64,;.43,-9.5,;2.97,-10.32,;3.45,-8.85,;4.95,-8.53,;5.43,-7.07,;5.98,-9.68,;-.49,-12.58,;-1.83,-11.82,)| Show InChI InChI=1S/C18H20N6O3S/c1-11(22-23-18(19)20)16-10-21-17-8-3-12(9-15(16)17)24-28(25,26)14-6-4-13(27-2)5-7-14/h3-10,21,24H,1-2H3,(H4,19,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163077 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12 Show InChI InChI=1S/C23H24ClN3O2S2/c1-14-18-11-16(24)3-6-22(18)30-23(14)31(28,29)26-17-4-5-21-19(12-17)20(13-25-21)15-7-9-27(2)10-8-15/h3-6,11-13,15,25-26H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300669 (2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...) Show SMILES NC(=N)N\N=C1/CCc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 Show InChI InChI=1S/C15H14ClN7O2S2/c16-12-13(23-5-6-26-15(23)19-12)27(24,25)22-9-3-1-8-2-4-11(10(8)7-9)20-21-14(17)18/h1,3,5-7,22H,2,4H2,(H4,17,18,21)/b20-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163052 (6-Chloro-imidazo[2,1-b]thiazole-5-sulfonic acid [1...) Show SMILES CN(C)CCn1ccc2cc(NS(=O)(=O)c3c(Cl)nc4sccn34)ccc12 Show InChI InChI=1S/C17H18ClN5O2S2/c1-21(2)7-8-22-6-5-12-11-13(3-4-14(12)22)20-27(24,25)16-15(18)19-17-23(16)9-10-26-17/h3-6,9-11,20H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C15H13ClN4O2S2/c16-13-14(19-7-8-23-15(19)18-13)24(21,22)20-9-10(5-6-17)11-3-1-2-4-12(11)20/h1-4,7-9H,5-6,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34148 (CHEMBL371292 | piperidinylindole, 7) Show SMILES O=S(=O)(c1ccccc1)n1cc(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c22-24(23,16-8-2-1-3-9-16)21-14-18(15-7-6-12-20-13-15)17-10-4-5-11-19(17)21/h1-5,8-11,14-15,20H,6-7,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	-51.6	n/a	n/a	24	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C15H13ClN4O2S2/c16-13-14(19-7-8-23-15(19)18-13)24(21,22)20-9-10(5-6-17)11-3-1-2-4-12(11)20/h1-4,7-9H,5-6,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2	-51.6	n/a	n/a	6.5	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34141 (CHEMBL76237 | MS-245) Show SMILES COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2	-51.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34141 (CHEMBL76237 | MS-245) Show SMILES COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C15H13ClN4O2S2/c16-13-14(19-7-8-23-15(19)18-13)24(21,22)20-9-10(5-6-17)11-3-1-2-4-12(11)20/h1-4,7-9H,5-6,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34152 (CHEMBL362628 | E-6801) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 Show InChI InChI=1S/C17H18ClN5O2S2/c1-22(2)6-5-11-10-19-14-4-3-12(9-13(11)14)21-27(24,25)16-15(18)20-17-23(16)7-8-26-17/h3-4,7-10,19,21H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34152 (CHEMBL362628 | E-6801) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 Show InChI InChI=1S/C17H18ClN5O2S2/c1-22(2)6-5-11-10-19-14-4-3-12(9-13(11)14)21-27(24,25)16-15(18)20-17-23(16)7-8-26-17/h3-4,7-10,19,21H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34152 (CHEMBL362628 | E-6801) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 Show InChI InChI=1S/C17H18ClN5O2S2/c1-22(2)6-5-11-10-19-14-4-3-12(9-13(11)14)21-27(24,25)16-15(18)20-17-23(16)7-8-26-17/h3-4,7-10,19,21H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	-51.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34152 (CHEMBL362628 | E-6801) Show SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 Show InChI InChI=1S/C17H18ClN5O2S2/c1-22(2)6-5-11-10-19-14-4-3-12(9-13(11)14)21-27(24,25)16-15(18)20-17-23(16)7-8-26-17/h3-4,7-10,19,21H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300674 (6-chloro-N-[3-(4,5-dihydro-1H-imidazol-2-ylhydrazo...) Show SMILES Clc1nc2sccn2c1S(=O)(=O)Nc1ccc2CC\C(=N/NC3=NCCN3)c2c1 |t:24| Show InChI InChI=1S/C17H16ClN7O2S2/c18-14-15(25-7-8-28-17(25)21-14)29(26,27)24-11-3-1-10-2-4-13(12(10)9-11)22-23-16-19-5-6-20-16/h1,3,7-9,24H,2,4-6H2,(H2,19,20,23)/b22-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300671 (2-(5-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...) Show SMILES NC(=N)N\N=C1/CCc2cc(NS(=O)(=O)c3c(Cl)nc4sccn34)ccc12 Show InChI InChI=1S/C15H14ClN7O2S2/c16-12-13(23-5-6-26-15(23)19-12)27(24,25)22-9-2-3-10-8(7-9)1-4-11(10)20-21-14(17)18/h2-3,5-7,22H,1,4H2,(H4,17,18,21)/b20-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34156 (indenylsulfonamide, 28) Show SMILES CN1CCC(C1)C1=CCc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 |t:7| Show InChI InChI=1S/C19H19ClN4O2S2/c1-23-7-6-13(11-23)15-5-3-12-2-4-14(10-16(12)15)22-28(25,26)18-17(20)21-19-24(18)8-9-27-19/h2,4-5,8-10,13,22H,3,6-7,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	-50.6	1.60E+3	n/a	n/a	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50266553 (2-(1-benzyl-1H-inden-3-yl)-N,N-dimethylethanamine ...) Show SMILES CN(C)CCC1=CC(Cc2ccccc2)c2ccccc12 |t:5| Show InChI InChI=1S/C20H23N/c1-21(2)13-12-17-15-18(14-16-8-4-3-5-9-16)20-11-7-6-10-19(17)20/h3-11,15,18H,12-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50106250 (CHEMBL93868 | N,N-dimethyl-2-(1-(phenylsulfonyl)-1...) Show SMILES CN(C)CCc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H20N2O2S/c1-19(2)13-12-15-14-20(18-11-7-6-10-17(15)18)23(21,22)16-8-4-3-5-9-16/h3-11,14H,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34156 (indenylsulfonamide, 28) Show SMILES CN1CCC(C1)C1=CCc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 |t:7| Show InChI InChI=1S/C19H19ClN4O2S2/c1-23-7-6-13(11-23)15-5-3-12-2-4-14(10-16(12)15)22-28(25,26)18-17(20)21-19-24(18)8-9-27-19/h2,4-5,8-10,13,22H,3,6-7,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34149 (CHEMBL94422 | N-benzenesulfonylgramine antagonist,...) Show SMILES CN(C)Cc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18(2)12-14-13-19(17-11-7-6-10-16(14)17)22(20,21)15-8-4-3-5-9-15/h3-11,13H,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	-50.6	n/a	n/a	880	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163102 (5-Chloro-naphthalene-1-sulfonic acid [3-(2-diethyl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4c(Cl)cccc34)cc12 Show InChI InChI=1S/C24H26ClN3O2S/c1-3-28(4-2)14-13-17-16-26-23-12-11-18(15-21(17)23)27-31(29,30)24-10-6-7-19-20(24)8-5-9-22(19)25/h5-12,15-16,26-27H,3-4,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163097 (CHEMBL180425 | Naphthalene-1-sulfonic acid [3-(2-d...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C24H27N3O2S/c1-3-27(4-2)15-14-19-17-25-23-13-12-20(16-22(19)23)26-30(28,29)24-11-7-9-18-8-5-6-10-21(18)24/h5-13,16-17,25-26H,3-4,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163080 (CHEMBL176292 | Naphthalene-2-sulfonic acid [3-(2-d...) Show SMILES CCCN(CCC)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 Show InChI InChI=1S/C26H31N3O2S/c1-3-14-29(15-4-2)16-13-22-19-27-26-12-10-23(18-25(22)26)28-32(30,31)24-11-9-20-7-5-6-8-21(20)17-24/h5-12,17-19,27-28H,3-4,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163059 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI InChI=1S/C23H24ClN3O2S2/c1-15-19-12-17(24)4-7-22(19)30-23(15)31(28,29)26-18-5-6-21-20(13-18)16(14-25-21)8-11-27-9-2-3-10-27/h4-7,12-14,25-26H,2-3,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300673 (2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...) Show SMILES [#6]-[#7](-c1ccc2-[#6]-[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c2c1)S(=O)(=O)c1c(Cl)nc2sccn12 |w:9.9| Show InChI InChI=1S/C16H16ClN7O2S2/c1-23(28(25,26)14-13(17)20-16-24(14)6-7-27-16)10-4-2-9-3-5-12(11(9)8-10)21-22-15(18)19/h2,4,6-8H,3,5H2,1H3,(H4,18,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163086 (CHEMBL427134 | Naphthalene-2-sulfonic acid [3-(2-p...) Show SMILES O=S(=O)(Nc1ccc2[nH]cc(CCN3CCCC3)c2c1)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H25N3O2S/c28-30(29,22-9-7-18-5-1-2-6-19(18)15-22)26-21-8-10-24-23(16-21)20(17-25-24)11-14-27-12-3-4-13-27/h1-2,5-10,15-17,25-26H,3-4,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34153 (CHEMBL476006 | indenylsulfonamide, 14) Show SMILES CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 |c:5| Show InChI InChI=1S/C19H21ClN4O2S2/c1-12-10-13-4-5-14(11-16(13)15(12)6-7-23(2)3)22-28(25,26)18-17(20)21-19-24(18)8-9-27-19/h4-5,8-9,11,22H,6-7,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 675-87 (2009) Article DOI: 10.1021/jm8009469 BindingDB Entry DOI: 10.7270/Q2SN09V7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM34153 (CHEMBL476006 | indenylsulfonamide, 14) Show SMILES CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc12 |c:5| Show InChI InChI=1S/C19H21ClN4O2S2/c1-12-10-13-4-5-14(11-16(13)15(12)6-7-23(2)3)22-28(25,26)18-17(20)21-19-24(18)8-9-27-19/h4-5,8-9,11,22H,6-7,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	-49.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Universitat de Barcelona					Assay Description Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...				Bioorg Med Chem 17: 7387-97 (2009) Article DOI: 10.1016/j.bmc.2009.08.006 BindingDB Entry DOI: 10.7270/Q2RR1WKS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163098 (CHEMBL367867 | Naphthalene-1-sulfonic acid [3-(2-p...) Show SMILES O=S(=O)(Nc1ccc2[nH]cc(CCN3CCCC3)c2c1)c1cccc2ccccc12 Show InChI InChI=1S/C24H25N3O2S/c28-30(29,24-9-5-7-18-6-1-2-8-21(18)24)26-20-10-11-23-22(16-20)19(17-25-23)12-15-27-13-3-4-14-27/h1-2,5-11,16-17,25-26H,3-4,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163040 (CHEMBL361230 | Naphthalene-1-sulfonic acid [3-(1-m...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C24H25N3O2S/c1-27-13-11-18(12-14-27)22-16-25-23-10-9-19(15-21(22)23)26-30(28,29)24-8-4-6-17-5-2-3-7-20(17)24/h2-10,15-16,18,25-26H,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300672 (2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...) Show SMILES CC1(C)C\C(=N/NC(N)=N)c2cc(NS(=O)(=O)c3c(Cl)nc4sccn34)ccc12 Show InChI InChI=1S/C17H18ClN7O2S2/c1-17(2)8-12(22-23-15(19)20)10-7-9(3-4-11(10)17)24-29(26,27)14-13(18)21-16-25(14)5-6-28-16/h3-7,24H,8H2,1-2H3,(H4,19,20,23)/b22-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163055 (5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) Show SMILES CN(C)Cc1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12 Show InChI InChI=1S/C20H20ClN3O2S2/c1-12-16-8-14(21)4-7-19(16)27-20(12)28(25,26)23-15-5-6-18-17(9-15)13(10-22-18)11-24(2)3/h4-10,22-23H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50163034 (CHEMBL175471 | Naphthalene-2-sulfonic acid [3-(2-d...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 Show InChI InChI=1S/C24H27N3O2S/c1-3-27(4-2)14-13-20-17-25-24-12-10-21(16-23(20)24)26-30(28,29)22-11-9-18-7-5-6-8-19(18)15-22/h5-12,15-17,25-26H,3-4,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Dr. Esteve S.A. Curated by ChEMBL					Assay Description Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells				J Med Chem 48: 1781-95 (2005) Article DOI: 10.1021/jm049615n BindingDB Entry DOI: 10.7270/Q2ZP45N9
					More data for this Ligand-Target Pair

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