Compile Data Set for Download or QSAR

Found 56 hits with Last Name = 'muraoka' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298278 (CHEMBL574392 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ncccc1OCCCO Show InChI InChI=1S/C34H47N5O4/c1-23(2)28-20-26(35)21-29(24(3)4)31(28)38-33(41)37-22-34(25-9-6-10-27(19-25)42-5)12-15-39(16-13-34)32-30(11-7-14-36-32)43-18-8-17-40/h6-7,9-11,14,19-21,23-24,40H,8,12-13,15-18,22,35H2,1-5H3,(H2,37,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175766 (1-(1-butyl-4-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(ccnc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C31H37N5O3/c1-7-8-17-36-29-24(13-10-15-33-29)25(21-11-9-12-22(18-21)39-6)28(30(36)37)35-31(38)34-27-23(19(2)3)14-16-32-26(27)20(4)5/h9-16,18-20H,7-8,17H2,1-6H3,(H2,34,35,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175771 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C32H39N5O3/c1-7-8-15-37-30-24(13-10-14-34-30)27(21-11-9-12-23(16-21)40-6)29(31(37)38)36-32(39)35-28-25(19(2)3)17-22(33)18-26(28)20(4)5/h9-14,16-20H,7-8,15,33H2,1-6H3,(H2,35,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175772 (1-(1-butyl-4-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(cccc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C32H38N4O3/c1-7-8-18-36-30-26(16-11-17-33-30)27(22-12-9-13-23(19-22)39-6)29(31(36)37)35-32(38)34-28-24(20(2)3)14-10-15-25(28)21(4)5/h9-17,19-21H,7-8,18H2,1-6H3,(H2,34,35,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175767 (1-(3-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(ccc(N)c2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C32H39N5O3/c1-7-8-17-37-30-24(13-10-16-34-30)27(21-11-9-12-22(18-21)40-6)29(31(37)38)36-32(39)35-28-23(19(2)3)14-15-25(33)26(28)20(4)5/h9-16,18-20H,7-8,17,33H2,1-6H3,(H2,35,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298281 (CHEMBL1091036 | N-(4-Amino-2,6-diisopropylphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCCO Show InChI InChI=1S/C35H48N4O4/c1-24(2)29-21-27(36)22-30(25(3)4)33(29)38-34(41)37-23-35(26-10-8-11-28(20-26)42-5)14-16-39(17-15-35)31-12-6-7-13-32(31)43-19-9-18-40/h6-8,10-13,20-22,24-25,40H,9,14-19,23,36H2,1-5H3,(H2,37,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175765 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50175765 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175765 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276562 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-butoxyp...) Show SMILES CCCCOc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C36H50N4O3/c1-7-8-20-43-33-15-10-9-14-32(33)40-18-16-36(17-19-40,27-12-11-13-29(21-27)42-6)24-38-35(41)39-34-30(25(2)3)22-28(37)23-31(34)26(4)5/h9-15,21-23,25-26H,7-8,16-20,24,37H2,1-6H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276493 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C33H41F3N4O2/c1-21(2)26-18-25(37)19-27(22(3)4)30(26)39-31(41)38-20-32(23-9-8-10-24(17-23)33(34,35)36)13-15-40(16-14-32)28-11-6-7-12-29(28)42-5/h6-12,17-19,21-22H,13-16,20,37H2,1-5H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276562 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-butoxyp...) Show SMILES CCCCOc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C36H50N4O3/c1-7-8-20-43-33-15-10-9-14-32(33)40-18-16-36(17-19-40,27-12-11-13-29(21-27)42-6)24-38-35(41)39-34-30(25(2)3)22-28(37)23-31(34)26(4)5/h9-15,21-23,25-26H,7-8,16-20,24,37H2,1-6H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276483 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-23(2)28-15-10-16-29(24(3)4)30(28)34-31(36)33-22-32(25-11-9-14-27(21-25)37-5)17-19-35(20-18-32)26-12-7-6-8-13-26/h6-16,21,23-24H,17-20,22H2,1-5H3,(H2,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276483 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-23(2)28-15-10-16-29(24(3)4)30(28)34-31(36)33-22-32(25-11-9-14-27(21-25)37-5)17-19-35(20-18-32)26-12-7-6-8-13-26/h6-16,21,23-24H,17-20,22H2,1-5H3,(H2,33,34,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276487 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H44N4O3/c1-22(2)27-19-25(34)20-28(23(3)4)31(27)36-32(38)35-21-33(24-10-9-11-26(18-24)39-5)14-16-37(17-15-33)29-12-7-8-13-30(29)40-6/h7-13,18-20,22-23H,14-17,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276487 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H44N4O3/c1-22(2)27-19-25(34)20-28(23(3)4)31(27)36-32(38)35-21-33(24-10-9-11-26(18-24)39-5)14-16-37(17-15-33)29-12-7-8-13-30(29)40-6/h7-13,18-20,22-23H,14-17,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298286 (CHEMBL574471 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC(C)C Show InChI InChI=1S/C35H48N4O3/c1-23(2)29-20-27(36)21-30(24(3)4)33(29)38-34(40)37-22-35(26-11-10-12-28(19-26)41-7)15-17-39(18-16-35)31-13-8-9-14-32(31)42-25(5)6/h8-14,19-21,23-25H,15-18,22,36H2,1-7H3,(H2,37,38,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276485 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H42N4O2/c1-22(2)28-19-25(33)20-29(23(3)4)30(28)35-31(37)34-21-32(24-10-9-13-27(18-24)38-5)14-16-36(17-15-32)26-11-7-6-8-12-26/h6-13,18-20,22-23H,14-17,21,33H2,1-5H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276485 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H42N4O2/c1-22(2)28-19-25(33)20-29(23(3)4)30(28)35-31(37)34-21-32(24-10-9-13-27(18-24)38-5)14-16-36(17-15-32)26-11-7-6-8-12-26/h6-13,18-20,22-23H,14-17,21,33H2,1-5H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175775 (1-(3-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCO)c2)c(NC(=O)Nc2c(ccc(N)c2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C34H43N5O4/c1-6-7-17-39-32-26(13-9-16-36-32)29(23-11-8-12-24(20-23)43-19-10-18-40)31(33(39)41)38-34(42)37-30-25(21(2)3)14-15-27(35)28(30)22(4)5/h8-9,11-16,20-22,40H,6-7,10,17-19,35H2,1-5H3,(H2,37,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276494 (1-(4-amino-2,6-diisopropylphenyl)-3-((1,4-bis(2-me...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1ccccc1OC Show InChI InChI=1S/C33H44N4O3/c1-22(2)25-19-24(34)20-26(23(3)4)31(25)36-32(38)35-21-33(27-11-7-9-13-29(27)39-5)15-17-37(18-16-33)28-12-8-10-14-30(28)40-6/h7-14,19-20,22-23H,15-18,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276484 (1-(2,6-diisopropylphenyl)-3-((1-(2-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H43N3O3/c1-23(2)27-13-10-14-28(24(3)4)31(27)35-32(37)34-22-33(25-11-9-12-26(21-25)38-5)17-19-36(20-18-33)29-15-7-8-16-30(29)39-6/h7-16,21,23-24H,17-20,22H2,1-6H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276565 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCC(F)(F)F Show InChI InChI=1S/C34H43F3N4O3/c1-22(2)27-18-25(38)19-28(23(3)4)31(27)40-32(42)39-20-33(24-9-8-10-26(17-24)43-5)13-15-41(16-14-33)29-11-6-7-12-30(29)44-21-34(35,36)37/h6-12,17-19,22-23H,13-16,20-21,38H2,1-5H3,(H2,39,40,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276565 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCC(F)(F)F Show InChI InChI=1S/C34H43F3N4O3/c1-22(2)27-18-25(38)19-28(23(3)4)31(27)40-32(42)39-20-33(24-9-8-10-26(17-24)43-5)13-15-41(16-14-33)29-11-6-7-12-30(29)44-21-34(35,36)37/h6-12,17-19,22-23H,13-16,20-21,38H2,1-5H3,(H2,39,40,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276488 (1-(4-amino-2,6-diisopropylphenyl)-3-((1,4-bis(3-me...) Show SMILES COc1cccc(c1)N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C33H44N4O3/c1-22(2)29-18-25(34)19-30(23(3)4)31(29)36-32(38)35-21-33(24-9-7-11-27(17-24)39-5)13-15-37(16-14-33)26-10-8-12-28(20-26)40-6/h7-12,17-20,22-23H,13-16,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276488 (1-(4-amino-2,6-diisopropylphenyl)-3-((1,4-bis(3-me...) Show SMILES COc1cccc(c1)N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C33H44N4O3/c1-22(2)29-18-25(34)19-30(23(3)4)31(29)36-32(38)35-21-33(24-9-7-11-27(17-24)39-5)13-15-37(16-14-33)26-10-8-12-28(20-26)40-6/h7-12,17-20,22-23H,13-16,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276563 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1ccc(cc1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H44N4O3/c1-22(2)27-19-25(34)20-28(23(3)4)31(27)36-32(38)35-21-33(24-11-13-26(39-5)14-12-24)15-17-37(18-16-33)29-9-7-8-10-30(29)40-6/h7-14,19-20,22-23H,15-18,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175773 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCCO)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C35H45N5O4/c1-6-7-16-40-33-27(14-11-15-37-33)30(24-12-10-13-26(19-24)44-18-9-8-17-41)32(34(40)42)39-35(43)38-31-28(22(2)3)20-25(36)21-29(31)23(4)5/h10-15,19-23,41H,6-9,16-18,36H2,1-5H3,(H2,38,39,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298279 (CHEMBL574388 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OCCCO)c1 Show InChI InChI=1S/C35H48N4O4/c1-24(2)29-21-27(36)22-30(25(3)4)33(29)38-34(41)37-23-35(26-10-8-11-28(20-26)43-19-9-18-40)14-16-39(17-15-35)31-12-6-7-13-32(31)42-5/h6-8,10-13,20-22,24-25,40H,9,14-19,23,36H2,1-5H3,(H2,37,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276564 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC(F)(F)F Show InChI InChI=1S/C33H41F3N4O3/c1-21(2)26-18-24(37)19-27(22(3)4)30(26)39-31(41)38-20-32(23-9-8-10-25(17-23)42-5)13-15-40(16-14-32)28-11-6-7-12-29(28)43-33(34,35)36/h6-12,17-19,21-22H,13-16,20,37H2,1-5H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276564 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC(F)(F)F Show InChI InChI=1S/C33H41F3N4O3/c1-21(2)26-18-24(37)19-27(22(3)4)30(26)39-31(41)38-20-32(23-9-8-10-25(17-23)42-5)13-15-40(16-14-32)28-11-6-7-12-29(28)43-33(34,35)36/h6-12,17-19,21-22H,13-16,20,37H2,1-5H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276492 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-fluorop...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(F)c1 Show InChI InChI=1S/C32H41FN4O2/c1-21(2)26-18-25(34)19-27(22(3)4)30(26)36-31(38)35-20-32(23-9-8-10-24(33)17-23)13-15-37(16-14-32)28-11-6-7-12-29(28)39-5/h6-12,17-19,21-22H,13-16,20,34H2,1-5H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276486 (1-(3-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(ccc(N)c2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H44N4O3/c1-22(2)26-14-15-27(34)30(23(3)4)31(26)36-32(38)35-21-33(24-10-9-11-25(20-24)39-5)16-18-37(19-17-33)28-12-7-8-13-29(28)40-6/h7-15,20,22-23H,16-19,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276491 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1ccccc1 Show InChI InChI=1S/C32H42N4O2/c1-22(2)26-19-25(33)20-27(23(3)4)30(26)35-31(37)34-21-32(24-11-7-6-8-12-24)15-17-36(18-16-32)28-13-9-10-14-29(28)38-5/h6-14,19-20,22-23H,15-18,21,33H2,1-5H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276491 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1ccccc1 Show InChI InChI=1S/C32H42N4O2/c1-22(2)26-19-25(33)20-27(23(3)4)30(26)35-31(37)34-21-32(24-11-7-6-8-12-24)15-17-36(18-16-32)28-13-9-10-14-29(28)38-5/h6-14,19-20,22-23H,15-18,21,33H2,1-5H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298282 (CHEMBL573802 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCO Show InChI InChI=1S/C34H46N4O4/c1-23(2)28-20-26(35)21-29(24(3)4)32(28)37-33(40)36-22-34(25-9-8-10-27(19-25)41-5)13-15-38(16-14-34)30-11-6-7-12-31(30)42-18-17-39/h6-12,19-21,23-24,39H,13-18,22,35H2,1-5H3,(H2,36,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50276489 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1ccc(cc1)N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C33H44N4O3/c1-22(2)29-19-25(34)20-30(23(3)4)31(29)36-32(38)35-21-33(24-8-7-9-28(18-24)40-6)14-16-37(17-15-33)26-10-12-27(39-5)13-11-26/h7-13,18-20,22-23H,14-17,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276489 (1-(4-amino-2,6-diisopropylphenyl)-3-((4-(3-methoxy...) Show SMILES COc1ccc(cc1)N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C33H44N4O3/c1-22(2)29-19-25(34)20-30(23(3)4)31(29)36-32(38)35-21-33(24-8-7-9-28(18-24)40-6)14-16-37(17-15-33)26-10-12-27(39-5)13-11-26/h7-13,18-20,22-23H,14-17,21,34H2,1-6H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298284 (CHEMBL574472 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCCN Show InChI InChI=1S/C35H49N5O3/c1-24(2)29-21-27(37)22-30(25(3)4)33(29)39-34(41)38-23-35(26-10-8-11-28(20-26)42-5)14-17-40(18-15-35)31-12-6-7-13-32(31)43-19-9-16-36/h6-8,10-13,20-22,24-25H,9,14-19,23,36-37H2,1-5H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298283 (CHEMBL574453 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OCCCN(C)C Show InChI InChI=1S/C37H53N5O3/c1-26(2)31-23-29(38)24-32(27(3)4)35(31)40-36(43)39-25-37(28-12-10-13-30(22-28)44-7)16-19-42(20-17-37)33-14-8-9-15-34(33)45-21-11-18-41(5)6/h8-10,12-15,22-24,26-27H,11,16-21,25,38H2,1-7H3,(H2,39,40,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175769 (1-(4-(aminomethyl)-2,6-diisopropylphenyl)-3-(1-but...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(cc(CN)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C33H41N5O3/c1-7-8-15-38-31-25(13-10-14-35-31)28(23-11-9-12-24(18-23)41-6)30(32(38)39)37-33(40)36-29-26(20(2)3)16-22(19-34)17-27(29)21(4)5/h9-14,16-18,20-21H,7-8,15,19,34H2,1-6H3,(H2,36,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175768 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-2-oxo...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCN3CCCC3)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C38H50N6O3/c1-6-7-20-44-36-30(15-11-16-40-36)33(27-13-10-14-29(22-27)47-21-12-19-43-17-8-9-18-43)35(37(44)45)42-38(46)41-34-31(25(2)3)23-28(39)24-32(34)26(4)5/h10-11,13-16,22-26H,6-9,12,17-21,39H2,1-5H3,(H2,41,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175764 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-4-(3-...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCN(CC)CC)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C38H52N6O3/c1-8-11-20-44-36-30(17-13-18-40-36)33(27-15-12-16-29(22-27)47-21-14-19-43(9-2)10-3)35(37(44)45)42-38(46)41-34-31(25(4)5)23-28(39)24-32(34)26(6)7/h12-13,15-18,22-26H,8-11,14,19-21,39H2,1-7H3,(H2,41,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	452	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50069900 (2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)...) Show SMILES CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C Show InChI InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50069900 (2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)...) Show SMILES CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C Show InChI InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175763 (1-(4-amino-2,6-diisopropylphenyl)-3-(1-butyl-2-oxo...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OCCCN3CCCCC3)c2)c(NC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C39H52N6O3/c1-6-7-21-45-37-31(16-12-17-41-37)34(28-14-11-15-30(23-28)48-22-13-20-44-18-9-8-10-19-44)36(38(45)46)43-39(47)42-35-32(26(2)3)24-29(40)25-33(35)27(4)5/h11-12,14-17,23-27H,6-10,13,18-22,40H2,1-5H3,(H2,42,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276482 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES CCCN1CCC(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)(CC1)c1cccc(OC)c1 Show InChI InChI=1S/C29H43N3O2/c1-7-16-32-17-14-29(15-18-32,23-10-8-11-24(19-23)34-6)20-30-28(33)31-27-25(21(2)3)12-9-13-26(27)22(4)5/h8-13,19,21-22H,7,14-18,20H2,1-6H3,(H2,30,31,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	547	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276481 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(C)CC1 Show InChI InChI=1S/C27H39N3O2/c1-19(2)23-11-8-12-24(20(3)4)25(23)29-26(31)28-18-27(13-15-30(5)16-14-27)21-9-7-10-22(17-21)32-6/h7-12,17,19-20H,13-16,18H2,1-6H3,(H2,28,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	664	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50175774 (1-(1-butyl-4-(3-methoxyphenyl)-2-oxo-1,2-dihydro-1...) Show SMILES CCCCn1c2ncccc2c(-c2cccc(OC)c2)c(NC(=O)Nc2c(cc(CN(CC)CC)cc2C(C)C)C(C)C)c1=O Show InChI InChI=1S/C37H49N5O3/c1-9-12-19-42-35-29(17-14-18-38-35)32(27-15-13-16-28(22-27)45-8)34(36(42)43)40-37(44)39-33-30(24(4)5)20-26(21-31(33)25(6)7)23-41(10-2)11-3/h13-18,20-22,24-25H,9-12,19,23H2,1-8H3,(H2,39,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against ACAT in rat macrophages				Bioorg Med Chem Lett 16: 44-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.056 BindingDB Entry DOI: 10.7270/Q2PG1SH8
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50298280 (CHEMBL574266 | N-(4-Amino-2,6-diisopropylphenyl)-N...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(O)c1 Show InChI InChI=1S/C32H42N4O3/c1-21(2)26-18-24(33)19-27(22(3)4)30(26)35-31(38)34-20-32(23-9-8-10-25(37)17-23)13-15-36(16-14-32)28-11-6-7-12-29(28)39-5/h6-12,17-19,21-22,37H,13-16,20,33H2,1-5H3,(H2,34,35,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	797	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair

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