Compile Data Set for Download or QSAR

Found 287 hits with Last Name = 'plé' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381945 (CHEMBL2023477) Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C25H25N3O6/c1-14-15(2)34-28-25(14)27-24(29)10-16-6-7-17(11-21(16)30-3)33-20-8-9-26-19-13-23(32-5)22(31-4)12-18(19)20/h6-9,11-13H,10H2,1-5H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381946 (CHEMBL2023485) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)[nH]n1 Show InChI InChI=1S/C25H26N4O5/c1-5-16-11-24(29-28-16)27-25(30)10-15-6-7-17(12-21(15)31-2)34-20-8-9-26-19-14-23(33-4)22(32-3)13-18(19)20/h6-9,11-14H,5,10H2,1-4H3,(H2,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381931 (CHEMBL2023476) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4ncc(C)s4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C23H21N3O4S/c1-14-13-25-23(31-14)26-22(27)10-15-4-5-17(12-21(15)29-3)30-20-8-9-24-19-11-16(28-2)6-7-18(19)20/h4-9,11-13H,10H2,1-3H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381947 (CHEMBL2023482) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)no1 Show InChI InChI=1S/C24H23N3O5/c1-4-16-14-23(27-32-16)26-24(28)11-15-5-6-18(13-22(15)30-3)31-21-9-10-25-20-12-17(29-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381948 (CHEMBL2023486) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)[nH]n1 Show InChI InChI=1S/C24H24N4O4/c1-4-16-12-23(28-27-16)26-24(29)11-15-5-6-18(14-22(15)31-3)32-21-9-10-25-20-13-17(30-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H2,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381949 (CHEMBL2023118) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)cn1 Show InChI InChI=1S/C24H24N4O4/c1-4-28-15-17(14-26-28)27-24(29)11-16-5-6-19(13-23(16)31-3)32-22-9-10-25-21-12-18(30-2)7-8-20(21)22/h5-10,12-15H,4,11H2,1-3H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381923 (CHEMBL2023117) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)cn1 Show InChI InChI=1S/C25H26N4O5/c1-5-29-15-17(14-27-29)28-25(30)10-16-6-7-18(11-22(16)31-2)34-21-8-9-26-20-13-24(33-4)23(32-3)12-19(20)21/h6-9,11-15H,5,10H2,1-4H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381936 (CHEMBL2023478) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4noc(C)c4C)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C24H23N3O5/c1-14-15(2)32-27-24(14)26-23(28)11-16-5-6-18(13-22(16)30-4)31-21-9-10-25-20-12-17(29-3)7-8-19(20)21/h5-10,12-13H,11H2,1-4H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340572 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES COc1cc(CO)cc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C27H34N6O4/c1-31(22-13-20(19-34)14-25(18-22)35-2)26-3-4-28-27(30-26)29-21-15-23(32-5-9-36-10-6-32)17-24(16-21)33-7-11-37-12-8-33/h3-4,13-18,34H,5-12,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340570 ((2-chloro-5-((2-(3,5-dimorpholinophenylamino)pyrim...) Show SMILES CN(c1ccc(Cl)c(CO)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H31ClN6O3/c1-31(21-2-3-24(27)19(14-21)18-34)25-4-5-28-26(30-25)29-20-15-22(32-6-10-35-11-7-32)17-23(16-20)33-8-12-36-13-9-33/h2-5,14-17,34H,6-13,18H2,1H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381930 (CHEMBL2023495) Show SMILES CCn1cc(NC(=O)Cc2ncc(Oc3ccnc4cc(OC)ccc34)cc2OC)cn1 Show InChI InChI=1S/C23H23N5O4/c1-4-28-14-15(12-26-28)27-23(29)11-20-22(31-3)10-17(13-25-20)32-21-7-8-24-19-9-16(30-2)5-6-18(19)21/h5-10,12-14H,4,11H2,1-3H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381924 (CHEMBL2023484) Show SMILES CCc1cn[nH]c1NC(=O)Cc1ccc(Oc2ccnc3cc(OC)ccc23)cc1OC Show InChI InChI=1S/C24H24N4O4/c1-4-15-14-26-28-24(15)27-23(29)11-16-5-6-18(13-22(16)31-3)32-21-9-10-25-20-12-17(30-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H2,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340576 (CHEMBL1762525 | N2-(3,5-dimorpholinophenyl)-N4-(3-...) Show SMILES COc1cccc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H32N6O3/c1-30(21-4-3-5-24(19-21)33-2)25-6-7-27-26(29-25)28-20-16-22(31-8-12-34-13-9-31)18-23(17-20)32-10-14-35-15-11-32/h3-7,16-19H,8-15H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340566 (CHEMBL1762535 | N2-(3,5-dimorpholinophenyl)-N4-(5-...) Show SMILES COc1cncc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H31N7O3/c1-30(22-16-23(33-2)18-26-17-22)24-3-4-27-25(29-24)28-19-13-20(31-5-9-34-10-6-31)15-21(14-19)32-7-11-35-12-8-32/h3-4,13-18H,5-12H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340551 ((3-(isopropyl(2-(3-(methylsulfonyl)-5-morpholinoph...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C26H33N5O4S/c1-18(2)31(24-13-20(17-32)6-5-19(24)3)25-7-8-27-26(29-25)28-21-14-22(30-9-11-35-12-10-30)16-23(15-21)36(4,33)34/h5-8,13-16,18,32H,9-12,17H2,1-4H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381922 (CHEMBL2023800) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cn2)cn1 Show InChI InChI=1S/C23H23N5O4/c1-4-28-14-16(12-26-28)27-23(29)9-15-5-6-17(13-25-15)32-20-7-8-24-19-11-22(31-3)21(30-2)10-18(19)20/h5-8,10-14H,4,9H2,1-3H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381929 (CHEMBL2023115) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2OC)cn1 Show InChI InChI=1S/C24H25N5O5/c1-5-29-13-16(12-27-29)28-23(30)8-15-6-7-17(9-20(15)31-2)34-24-18-10-21(32-3)22(33-4)11-19(18)25-14-26-24/h6-7,9-14H,5,8H2,1-4H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50381926 (CHEMBL2023489 | CHEMBL2023803) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cn(C)nc4C)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C24H24N4O4/c1-15-21(14-28(2)27-15)26-24(29)11-16-5-6-18(13-23(16)31-4)32-22-9-10-25-20-12-17(30-3)7-8-19(20)22/h5-10,12-14H,11H2,1-4H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50381923 (CHEMBL2023117) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)cn1 Show InChI InChI=1S/C25H26N4O5/c1-5-29-15-17(14-27-29)28-25(30)10-16-6-7-18(11-22(16)31-2)34-21-8-9-26-20-13-24(33-4)23(32-3)12-19(20)21/h6-9,11-15H,5,10H2,1-4H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF-1R				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381928 (CHEMBL2023802) Show SMILES CCOc1cc2nccc(Oc3cnc(CC(=O)Nc4[nH]nc(CC)c4C)c(OC)c3)c2cc1OC Show InChI InChI=1S/C26H29N5O5/c1-6-18-15(3)26(31-30-18)29-25(32)13-20-22(33-4)10-16(14-28-20)36-21-8-9-27-19-12-24(35-7-2)23(34-5)11-17(19)21/h8-12,14H,6-7,13H2,1-5H3,(H2,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340555 ((4-methyl-3-(methyl(2-(3-(methylsulfonyl)-5-morpho...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C24H29N5O4S/c1-17-4-5-18(16-30)12-22(17)28(2)23-6-7-25-24(27-23)26-19-13-20(29-8-10-33-11-9-29)15-21(14-19)34(3,31)32/h4-7,12-15,30H,8-11,16H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50381946 (CHEMBL2023485) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)[nH]n1 Show InChI InChI=1S/C25H26N4O5/c1-5-16-11-24(29-28-16)27-25(30)10-15-6-7-17(12-21(15)31-2)34-20-8-9-26-19-14-23(33-4)22(32-3)13-18(19)20/h6-9,11-14H,5,10H2,1-4H3,(H2,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381920 (CHEMBL2023119) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4ccc(OC)cc34)cc2OC)cn1 Show InChI InChI=1S/C24H24N4O4/c1-4-28-15-17(14-26-28)27-24(29)11-16-5-6-19(13-23(16)31-3)32-22-9-10-25-21-8-7-18(30-2)12-20(21)22/h5-10,12-15H,4,11H2,1-3H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340554 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-3-34(26-16-22(20-35)5-4-21(26)2)27-6-7-29-28(31-27)30-23-17-24(32-8-12-36-13-9-32)19-25(18-23)33-10-14-37-15-11-33/h4-7,16-19,35H,3,8-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50381948 (CHEMBL2023486) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)[nH]n1 Show InChI InChI=1S/C24H24N4O4/c1-4-16-12-23(28-27-16)26-24(29)11-15-5-6-18(14-22(15)31-3)32-21-9-10-25-20-13-17(30-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H2,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340571 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H34N6O3/c1-20-3-4-21(19-34)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-11-35-12-8-32)18-24(17-22)33-9-13-36-14-10-33/h3-6,15-18,34H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340562 ((4-methyl-3-(methyl(2-(3-(4-methylpiperazin-1-yl)-...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCN(C)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H37N7O2/c1-21-4-5-22(20-36)16-26(21)33(3)27-6-7-29-28(31-27)30-23-17-24(34-10-8-32(2)9-11-34)19-25(18-23)35-12-14-37-15-13-35/h4-7,16-19,36H,8-15,20H2,1-3H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50362058 (CHEMBL1940274) Show SMILES COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cnn(c4)C(C)C)cc3)c2cc1OC Show InChI InChI=1S/C24H25N5O4/c1-15(2)29-13-17(12-27-29)28-23(30)9-16-5-7-18(8-6-16)33-24-19-10-21(31-3)22(32-4)11-20(19)25-14-26-24/h5-8,10-15H,9H2,1-4H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50381947 (CHEMBL2023482) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)no1 Show InChI InChI=1S/C24H23N3O5/c1-4-16-14-23(27-32-16)26-24(28)11-15-5-6-18(13-22(15)30-3)31-21-9-10-25-20-12-17(29-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF-1R				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381944 (CHEMBL2023801) Show SMILES CCc1n[nH]c(NC(=O)Cc2ncc(Oc3ccnc4cc(OC)c(OC)cc34)cc2OC)c1C Show InChI InChI=1S/C25H27N5O5/c1-6-17-14(2)25(30-29-17)28-24(31)12-19-21(32-3)9-15(13-27-19)35-20-7-8-26-18-11-23(34-5)22(33-4)10-16(18)20/h7-11,13H,6,12H2,1-5H3,(H2,28,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381926 (CHEMBL2023489 | CHEMBL2023803) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cn(C)nc4C)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C24H24N4O4/c1-15-21(14-28(2)27-15)26-24(29)11-16-5-6-18(13-23(16)31-4)32-22-9-10-25-20-12-17(30-3)7-8-19(20)22/h5-10,12-14H,11H2,1-4H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381938 (CHEMBL2023483) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4[nH]nc(C)c4C)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C24H24N4O4/c1-14-15(2)27-28-24(14)26-23(29)11-16-5-6-18(13-22(16)31-4)32-21-9-10-25-20-12-17(30-3)7-8-19(20)21/h5-10,12-13H,11H2,1-4H3,(H2,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381941 (CHEMBL2023492) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cnn(C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C23H22N4O4/c1-27-14-16(13-25-27)26-23(28)10-15-4-5-18(12-22(15)30-3)31-21-8-9-24-20-11-17(29-2)6-7-19(20)21/h4-9,11-14H,10H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381942 (CHEMBL2023493) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)nn4C)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C24H24N4O4/c1-15-11-23(28(2)27-15)26-24(29)12-16-5-6-18(14-22(16)31-4)32-21-9-10-25-20-13-17(30-3)7-8-19(20)21/h5-11,13-14H,12H2,1-4H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50174932 (CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...) Show SMILES COc1cnc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OC(C)C)c23)c1 Show InChI InChI=1S/C24H30ClN5O4/c1-16(2)34-21-13-17(33-8-4-5-30-6-9-32-10-7-30)11-19-22(21)24(28-15-27-19)29-20-12-18(31-3)14-26-23(20)25/h11-16H,4-10H2,1-3H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibitory activity against c-Src kinase				Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340556 ((3-((2-(3-methoxy-5-morpholinophenylamino)pyrimidi...) Show SMILES COc1cc(Nc2nccc(n2)N(C)c2cc(CO)ccc2C)cc(c1)N1CCOCC1 Show InChI InChI=1S/C24H29N5O3/c1-17-4-5-18(16-30)12-22(17)28(2)23-6-7-25-24(27-23)26-19-13-20(15-21(14-19)31-3)29-8-10-32-11-9-29/h4-7,12-15,30H,8-11,16H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340553 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C29H38N6O3/c1-21(2)35(27-16-23(20-36)5-4-22(27)3)28-6-7-30-29(32-28)31-24-17-25(33-8-12-37-13-9-33)19-26(18-24)34-10-14-38-15-11-34/h4-7,16-19,21,36H,8-15,20H2,1-3H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381937 (CHEMBL2023479) Show SMILES COc1ccc2nccc(Oc3ccc(CC(=O)Nc4noc(C)c4C)c(OC)c3)c2c1 Show InChI InChI=1S/C24H23N3O5/c1-14-15(2)32-27-24(14)26-23(28)11-16-5-6-18(13-22(16)30-4)31-21-9-10-25-20-8-7-17(29-3)12-19(20)21/h5-10,12-13H,11H2,1-4H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381925 (CHEMBL2023481) Show SMILES COc1cc(Oc2ccnc3ccc(F)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C23H20FN3O4/c1-13-14(2)31-27-23(13)26-22(28)10-15-4-6-17(12-21(15)29-3)30-20-8-9-25-19-7-5-16(24)11-18(19)20/h4-9,11-12H,10H2,1-3H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50174939 (CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...) Show SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OC4CCOCC4)c23)n1 Show InChI InChI=1S/C26H32ClN5O5/c1-33-23-4-3-20(27)25(30-23)31-26-24-21(28-17-29-26)15-19(16-22(24)37-18-5-11-34-12-6-18)36-10-2-7-32-8-13-35-14-9-32/h3-4,15-18H,2,5-14H2,1H3,(H,28,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibitory activity against c-Src kinase				Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381950 (CHEMBL2023494) Show SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)ccnc2c1 Show InChI InChI=1S/C29H31N3O4/c1-19-12-20(18-32(2)3)14-22(13-19)31-29(33)15-21-6-7-24(17-28(21)35-5)36-27-10-11-30-26-16-23(34-4)8-9-25(26)27/h6-14,16-17H,15,18H2,1-5H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50381949 (CHEMBL2023118) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)cn1 Show InChI InChI=1S/C24H24N4O4/c1-4-28-15-17(14-26-28)27-24(29)11-16-5-6-19(13-23(16)31-3)32-22-9-10-25-21-12-18(30-2)7-8-20(21)22/h5-10,12-15H,4,11H2,1-3H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF-1R				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50381948 (CHEMBL2023486) Show SMILES CCc1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)[nH]n1 Show InChI InChI=1S/C24H24N4O4/c1-4-16-12-23(28-27-16)26-24(29)11-15-5-6-18(14-22(15)31-3)32-21-9-10-25-20-13-17(30-2)7-8-19(20)21/h5-10,12-14H,4,11H2,1-3H3,(H2,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF-1R				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340567 (CHEMBL1762534 | N2-(3,5-dimorpholinophenyl)-N4-(6-...) Show SMILES COc1cccc(n1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H31N7O3/c1-30(22-4-3-5-24(28-22)33-2)23-6-7-26-25(29-23)27-19-16-20(31-8-12-34-13-9-31)18-21(17-19)32-10-14-35-15-11-32/h3-7,16-18H,8-15H2,1-2H3,(H,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381939 (CHEMBL2023488) Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1cn(C)nc1C Show InChI InChI=1S/C25H26N4O5/c1-15-20(14-29(2)28-15)27-25(30)10-16-6-7-17(11-22(16)31-3)34-21-8-9-26-19-13-24(33-5)23(32-4)12-18(19)21/h6-9,11-14H,10H2,1-5H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381934 (CHEMBL2023474) Show SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(F)ccc34)cc2OC)cn1 Show InChI InChI=1S/C23H21FN4O3/c1-3-28-14-17(13-26-28)27-23(29)10-15-4-6-18(12-22(15)30-2)31-21-8-9-25-20-11-16(24)5-7-19(20)21/h4-9,11-14H,3,10H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340577 (CHEMBL1762524 | N4-(3-chlorophenyl)-N2-(3,5-dimorp...) Show SMILES CN(c1cccc(Cl)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H29ClN6O2/c1-30(21-4-2-3-19(26)15-21)24-5-6-27-25(29-24)28-20-16-22(31-7-11-33-12-8-31)18-23(17-20)32-9-13-34-14-10-32/h2-6,15-18H,7-14H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50174934 (CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...) Show SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCCC4)cc(OC(C)C)c23)n1 Show InChI InChI=1S/C24H30ClN5O3/c1-16(2)33-20-14-17(32-12-6-11-30-9-4-5-10-30)13-19-22(20)24(27-15-26-19)29-23-18(25)7-8-21(28-23)31-3/h7-8,13-16H,4-6,9-12H2,1-3H3,(H,26,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibitory activity against c-Src kinase				Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340560 ((4-methyl-3-(methyl(2-(3-morpholino-5-(morpholinom...) Show SMILES CN(c1ccnc(Nc2cc(CN3CCOCC3)cc(c2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-21-3-4-22(20-35)17-26(21)32(2)27-5-6-29-28(31-27)30-24-15-23(19-33-7-11-36-12-8-33)16-25(18-24)34-9-13-37-14-10-34/h3-6,15-18,35H,7-14,19-20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50381921 (CHEMBL2023480) Show SMILES COc1cc(Oc2ccnc3cc(F)ccc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C23H20FN3O4/c1-13-14(2)31-27-23(13)26-22(28)10-15-4-6-17(12-21(15)29-3)30-20-8-9-25-19-11-16(24)5-7-18(19)20/h4-9,11-12H,10H2,1-3H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem Lett 22: 3050-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.074 BindingDB Entry DOI: 10.7270/Q298881Z
					More data for this Ligand-Target Pair

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