Found 48 hits with Last Name = 'pong' and Initial = 'ss' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM85790
(Salmon MCH)Show SMILES CSCCC(NC(=O)C(NC(=O)C(N)CC(O)=O)C(C)O)C(=O)NC(CCCN=C(N)N)C(=O)NC1CSSCC(NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(NC(=O)C(CCSC)NC1=O)C(C)C)C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)C)C(O)=O |(16.32,3.32,;17.66,2.55,;18.99,3.32,;18.99,4.86,;20.32,5.63,;20.32,7.17,;21.66,7.94,;22.99,7.17,;21.66,9.48,;22.99,10.25,;22.99,11.79,;21.66,12.56,;24.33,12.56,;25.66,11.79,;24.33,14.1,;25.66,14.87,;25.66,16.41,;26.99,14.1,;20.32,10.25,;18.99,9.48,;20.32,11.79,;21.66,4.86,;22.99,5.63,;21.66,3.32,;22.99,2.55,;24.33,3.32,;24.33,4.86,;25.66,5.63,;25.66,7.17,;26.99,7.94,;26.99,9.48,;28.33,7.17,;22.99,1.01,;21.66,.24,;24.33,.24,;24.33,-1.3,;22.99,-2.07,;21.66,-1.3,;20.32,-2.07,;20.32,-3.61,;18.99,-4.38,;18.99,-5.92,;17.66,-6.69,;16.12,-6.69,;17.66,-8.23,;16.52,-9.26,;17.15,-10.66,;18.67,-10.5,;18.99,-9,;20.32,-8.23,;21.09,-6.9,;21.66,-9,;21.66,-10.54,;20.32,-11.31,;20.32,-12.85,;18.99,-13.62,;18.99,-15.16,;17.66,-15.93,;20.32,-15.93,;22.99,-8.23,;24.33,-9,;24.33,-10.54,;25.66,-8.23,;26.99,-9,;26.99,-10.54,;25.66,-11.31,;25.66,-12.85,;26.99,-13.62,;26.99,-15.16,;28.33,-12.85,;28.33,-11.31,;25.66,-6.69,;26.99,-5.92,;26.99,-4.38,;28.33,-6.69,;29.66,-5.92,;30.99,-6.69,;30.99,-8.23,;32.33,-5.92,;33.66,-6.69,;33.66,-8.23,;34.99,-9,;34.99,-10.54,;36.33,-11.31,;36.33,-12.85,;37.66,-10.54,;32.33,-4.38,;33.66,-3.61,;34.99,-4.38,;33.66,-2.07,;32.33,-1.3,;32.33,.24,;33.66,1.01,;30.99,1.01,;29.66,.24,;28.33,1.01,;28.33,2.55,;26.99,.24,;25.81,1.23,;26.08,2.75,;27.53,3.27,;27.8,4.79,;26.99,-1.3,;25.66,-2.07,;25.66,-3.61,;30.99,2.55,;32.33,3.32,;29.66,3.32,;28.33,-8.23,;29.66,-9,;28.33,-9.77,;17.66,-3.61,;17.66,-2.07,;16.32,-4.38,;14.99,-3.61,;14.99,-2.07,;13.66,-1.3,;12.26,-1.93,;11.23,-.79,;11.99,.54,;11.51,2,;12.54,3.15,;14.05,2.83,;14.53,1.37,;13.5,.22,;13.66,-4.38,;13.66,-5.92,;12.12,-3.61,;10.78,-4.38,;10.78,-5.92,;9.45,-6.69,;9.45,-8.23,;8.11,-9,;10.78,-9,;9.45,-3.61,;9.45,-2.07,;7.91,-4.38,;6.57,-3.61,;6.57,-2.07,;5.24,-1.3,;7.91,-1.3,;5.24,-4.38,;3.91,-3.61,;5.24,-5.92,)| Show InChI InChI=1S/C89H139N27O24S4/c1-43(2)67-82(135)101-40-64(119)102-53(18-12-30-97-87(91)92)74(127)113-68(44(3)4)83(136)109-59(36-47-22-24-49(118)25-23-47)77(130)107-58(20-14-32-99-89(95)96)85(138)116-33-15-21-63(116)81(134)111-62(80(133)108-60(37-48-39-100-52-17-11-10-16-50(48)52)78(131)104-55(26-27-65(120)121)75(128)114-69(45(5)6)86(139)140)42-144-143-41-61(79(132)105-57(29-35-142-9)76(129)112-67)110-72(125)54(19-13-31-98-88(93)94)103-73(126)56(28-34-141-8)106-84(137)70(46(7)117)115-71(124)51(90)38-66(122)123/h10-11,16-17,22-25,39,43-46,51,53-63,67-70,100,117-118H,12-15,18-21,26-38,40-42,90H2,1-9H3,(H,101,135)(H,102,119)(H,103,126)(H,104,131)(H,105,132)(H,106,137)(H,107,130)(H,108,133)(H,109,136)(H,110,125)(H,111,134)(H,112,129)(H,113,127)(H,114,128)(H,115,124)(H,120,121)(H,122,123)(H,139,140)(H4,91,92,97)(H4,93,94,98)(H4,95,96,99) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 98: 7564-9 (2001)
Article DOI: 10.1073/pnas.121170598
BindingDB Entry DOI: 10.7270/Q2RJ4H14 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049478
(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 Show InChI InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand |
J Med Chem 39: 1767-70 (1996)
Article DOI: 10.1021/jm960054c
BindingDB Entry DOI: 10.7270/Q2BK1BDG |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human)) | BDBM85789
([Phe13,Tyr19]MCH)Show SMILES CSCCC(NC(=O)C(CC(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC1CSSCC(NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC1=O)C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(N)=O)C(=O)NC(Cc1ccc(O)cc1)C(O)=O |(16.32,9.48,;17.66,10.25,;18.99,9.48,;20.32,10.25,;21.66,9.48,;22.99,10.25,;22.99,11.79,;21.66,12.56,;24.33,12.56,;24.33,14.1,;23.24,15.19,;23.63,16.68,;21.75,14.79,;25.66,11.79,;26.99,12.56,;26.99,14.1,;28.33,11.79,;28.33,10.25,;29.66,9.48,;29.66,7.94,;30.99,7.17,;32.33,7.94,;32.33,9.48,;30.99,10.25,;29.66,12.56,;31.15,12.16,;31.55,10.67,;32.48,12.93,;33.81,12.16,;32.48,14.47,;33.81,15.24,;33.81,16.78,;35.3,14.84,;21.66,7.94,;22.99,7.17,;20.32,7.17,;20.32,5.63,;18.99,4.86,;18.99,3.32,;17.66,2.55,;20.32,2.55,;21.66,4.86,;22.99,5.63,;21.66,3.32,;22.99,2.55,;24.33,3.32,;24.33,4.86,;25.66,5.63,;25.66,7.17,;26.99,7.94,;26.99,9.48,;28.33,7.17,;22.99,1.01,;21.66,.24,;24.33,.24,;24.33,-1.3,;22.99,-2.07,;21.66,-1.3,;20.32,-2.07,;20.32,-3.61,;18.99,-4.38,;18.99,-5.92,;17.66,-6.69,;16.12,-6.69,;17.66,-8.23,;16.52,-9.26,;17.15,-10.66,;18.67,-10.5,;18.99,-9,;20.32,-8.23,;21.09,-6.9,;21.66,-9,;21.66,-10.54,;20.32,-11.31,;20.32,-12.85,;18.99,-13.62,;18.99,-15.16,;17.66,-15.93,;20.32,-15.93,;22.99,-8.23,;24.33,-9,;24.33,-10.54,;25.66,-8.23,;26.99,-9,;26.99,-10.54,;25.66,-11.31,;25.66,-12.85,;26.99,-13.62,;28.33,-12.85,;28.33,-11.31,;25.66,-6.69,;26.99,-5.92,;26.99,-4.38,;28.33,-6.69,;29.66,-5.92,;30.99,-6.69,;30.99,-8.23,;32.33,-5.92,;33.66,-6.69,;33.66,-8.23,;34.99,-9,;34.99,-10.54,;36.33,-11.31,;36.33,-12.85,;37.66,-10.54,;32.33,-4.38,;33.66,-3.61,;34.99,-4.38,;33.66,-2.07,;32.33,-1.3,;32.33,.24,;33.66,1.01,;30.99,1.01,;30.99,2.55,;32.33,3.32,;32.33,4.86,;33.66,2.55,;29.66,.24,;28.33,1.01,;28.33,2.55,;26.99,.24,;25.81,1.23,;26.08,2.75,;27.53,3.27,;27.8,4.79,;26.99,-1.3,;25.66,-2.07,;25.66,-3.61,;28.33,-8.23,;29.66,-9,;28.33,-9.77,;17.66,-3.61,;17.66,-2.07,;16.32,-4.38,;14.99,-3.61,;14.99,-2.07,;13.66,-1.3,;12.26,-1.93,;11.23,-.79,;11.99,.54,;11.51,2,;12.54,3.15,;14.05,2.83,;14.53,1.37,;13.5,.22,;13.66,-4.38,;13.66,-5.92,;12.12,-3.61,;10.78,-4.38,;10.78,-5.92,;9.45,-6.69,;9.45,-8.23,;8.11,-9,;10.78,-9,;9.45,-3.61,;9.45,-2.07,;7.91,-4.38,;6.57,-3.61,;6.57,-2.07,;5.24,-1.3,;5.24,.24,;3.91,1.01,;2.57,.24,;1.24,1.01,;2.57,-1.3,;3.91,-2.07,;5.24,-4.38,;3.91,-3.61,;5.24,-5.92,)| Show InChI InChI=1S/C109H160N30O26S4/c1-57(2)45-74-90(148)122-54-85(142)123-68(27-17-39-118-107(112)113)95(153)138-88(59(5)6)104(162)134-77(48-61-23-13-10-14-24-61)97(155)128-73(29-19-41-120-109(116)117)105(163)139-42-20-30-83(139)103(161)137-82(102(160)132-78(50-63-53-121-67-26-16-15-25-65(63)67)99(157)125-70(35-36-84(111)141)92(150)135-80(106(164)165)49-62-31-33-64(140)34-32-62)56-169-168-55-81(101(159)127-72(38-44-167-8)93(151)130-74)136-91(149)69(28-18-40-119-108(114)115)124-96(154)75(46-58(3)4)131-94(152)71(37-43-166-7)126-100(158)79(52-87(145)146)133-98(156)76(47-60-21-11-9-12-22-60)129-89(147)66(110)51-86(143)144/h9-16,21-26,31-34,53,57-59,66,68-83,88,121,140H,17-20,27-30,35-52,54-56,110H2,1-8H3,(H2,111,141)(H,122,148)(H,123,142)(H,124,154)(H,125,157)(H,126,158)(H,127,159)(H,128,155)(H,129,147)(H,130,151)(H,131,152)(H,132,160)(H,133,156)(H,134,162)(H,135,150)(H,136,149)(H,137,161)(H,138,153)(H,143,144)(H,145,146)(H,164,165)(H4,112,113,118)(H4,114,115,119)(H4,116,117,120) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 98: 7564-9 (2001)
Article DOI: 10.1073/pnas.121170598
BindingDB Entry DOI: 10.7270/Q2RJ4H14 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 2
(Homo sapiens (Human)) | BDBM85789
([Phe13,Tyr19]MCH)Show SMILES CSCCC(NC(=O)C(CC(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC1CSSCC(NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC1=O)C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(N)=O)C(=O)NC(Cc1ccc(O)cc1)C(O)=O |(16.32,9.48,;17.66,10.25,;18.99,9.48,;20.32,10.25,;21.66,9.48,;22.99,10.25,;22.99,11.79,;21.66,12.56,;24.33,12.56,;24.33,14.1,;23.24,15.19,;23.63,16.68,;21.75,14.79,;25.66,11.79,;26.99,12.56,;26.99,14.1,;28.33,11.79,;28.33,10.25,;29.66,9.48,;29.66,7.94,;30.99,7.17,;32.33,7.94,;32.33,9.48,;30.99,10.25,;29.66,12.56,;31.15,12.16,;31.55,10.67,;32.48,12.93,;33.81,12.16,;32.48,14.47,;33.81,15.24,;33.81,16.78,;35.3,14.84,;21.66,7.94,;22.99,7.17,;20.32,7.17,;20.32,5.63,;18.99,4.86,;18.99,3.32,;17.66,2.55,;20.32,2.55,;21.66,4.86,;22.99,5.63,;21.66,3.32,;22.99,2.55,;24.33,3.32,;24.33,4.86,;25.66,5.63,;25.66,7.17,;26.99,7.94,;26.99,9.48,;28.33,7.17,;22.99,1.01,;21.66,.24,;24.33,.24,;24.33,-1.3,;22.99,-2.07,;21.66,-1.3,;20.32,-2.07,;20.32,-3.61,;18.99,-4.38,;18.99,-5.92,;17.66,-6.69,;16.12,-6.69,;17.66,-8.23,;16.52,-9.26,;17.15,-10.66,;18.67,-10.5,;18.99,-9,;20.32,-8.23,;21.09,-6.9,;21.66,-9,;21.66,-10.54,;20.32,-11.31,;20.32,-12.85,;18.99,-13.62,;18.99,-15.16,;17.66,-15.93,;20.32,-15.93,;22.99,-8.23,;24.33,-9,;24.33,-10.54,;25.66,-8.23,;26.99,-9,;26.99,-10.54,;25.66,-11.31,;25.66,-12.85,;26.99,-13.62,;28.33,-12.85,;28.33,-11.31,;25.66,-6.69,;26.99,-5.92,;26.99,-4.38,;28.33,-6.69,;29.66,-5.92,;30.99,-6.69,;30.99,-8.23,;32.33,-5.92,;33.66,-6.69,;33.66,-8.23,;34.99,-9,;34.99,-10.54,;36.33,-11.31,;36.33,-12.85,;37.66,-10.54,;32.33,-4.38,;33.66,-3.61,;34.99,-4.38,;33.66,-2.07,;32.33,-1.3,;32.33,.24,;33.66,1.01,;30.99,1.01,;30.99,2.55,;32.33,3.32,;32.33,4.86,;33.66,2.55,;29.66,.24,;28.33,1.01,;28.33,2.55,;26.99,.24,;25.81,1.23,;26.08,2.75,;27.53,3.27,;27.8,4.79,;26.99,-1.3,;25.66,-2.07,;25.66,-3.61,;28.33,-8.23,;29.66,-9,;28.33,-9.77,;17.66,-3.61,;17.66,-2.07,;16.32,-4.38,;14.99,-3.61,;14.99,-2.07,;13.66,-1.3,;12.26,-1.93,;11.23,-.79,;11.99,.54,;11.51,2,;12.54,3.15,;14.05,2.83,;14.53,1.37,;13.5,.22,;13.66,-4.38,;13.66,-5.92,;12.12,-3.61,;10.78,-4.38,;10.78,-5.92,;9.45,-6.69,;9.45,-8.23,;8.11,-9,;10.78,-9,;9.45,-3.61,;9.45,-2.07,;7.91,-4.38,;6.57,-3.61,;6.57,-2.07,;5.24,-1.3,;5.24,.24,;3.91,1.01,;2.57,.24,;1.24,1.01,;2.57,-1.3,;3.91,-2.07,;5.24,-4.38,;3.91,-3.61,;5.24,-5.92,)| Show InChI InChI=1S/C109H160N30O26S4/c1-57(2)45-74-90(148)122-54-85(142)123-68(27-17-39-118-107(112)113)95(153)138-88(59(5)6)104(162)134-77(48-61-23-13-10-14-24-61)97(155)128-73(29-19-41-120-109(116)117)105(163)139-42-20-30-83(139)103(161)137-82(102(160)132-78(50-63-53-121-67-26-16-15-25-65(63)67)99(157)125-70(35-36-84(111)141)92(150)135-80(106(164)165)49-62-31-33-64(140)34-32-62)56-169-168-55-81(101(159)127-72(38-44-167-8)93(151)130-74)136-91(149)69(28-18-40-119-108(114)115)124-96(154)75(46-58(3)4)131-94(152)71(37-43-166-7)126-100(158)79(52-87(145)146)133-98(156)76(47-60-21-11-9-12-22-60)129-89(147)66(110)51-86(143)144/h9-16,21-26,31-34,53,57-59,66,68-83,88,121,140H,17-20,27-30,35-52,54-56,110H2,1-8H3,(H2,111,141)(H,122,148)(H,123,142)(H,124,154)(H,125,157)(H,126,158)(H,127,159)(H,128,155)(H,129,147)(H,130,151)(H,131,152)(H,132,160)(H,133,156)(H,134,162)(H,135,150)(H,136,149)(H,137,161)(H,138,153)(H,143,144)(H,145,146)(H,164,165)(H4,112,113,118)(H4,114,115,119)(H4,116,117,120) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 98: 7564-9 (2001)
Article DOI: 10.1073/pnas.121170598
BindingDB Entry DOI: 10.7270/Q2RJ4H14 |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 2
(Homo sapiens (Human)) | BDBM85788
(MCH | hMCH)Show SMILES CSCCC(NC(=O)C(CC(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC1CSSCC(NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC1=O)C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)C)C(O)=O |(16.32,9.48,;17.66,10.25,;18.99,9.48,;20.32,10.25,;21.66,9.48,;22.99,10.25,;22.99,11.79,;21.66,12.56,;24.33,12.56,;24.33,14.1,;23.24,15.19,;23.63,16.68,;21.75,14.79,;25.66,11.79,;26.99,12.56,;26.99,14.1,;28.33,11.79,;28.33,10.25,;29.66,9.48,;29.66,7.94,;30.99,7.17,;32.33,7.94,;32.33,9.48,;30.99,10.25,;29.66,12.56,;31.15,12.16,;31.55,10.67,;32.48,12.93,;33.81,12.16,;32.48,14.47,;33.81,15.24,;33.81,16.78,;35.3,14.84,;21.66,7.94,;22.99,7.17,;20.32,7.17,;20.32,5.63,;18.99,4.86,;18.99,3.32,;17.66,2.55,;20.32,2.55,;21.66,4.86,;22.99,5.63,;21.66,3.32,;22.99,2.55,;24.33,3.32,;24.33,4.86,;25.66,5.63,;25.66,7.17,;26.99,7.94,;26.99,9.48,;28.33,7.17,;22.99,1.01,;21.66,.24,;24.33,.24,;24.33,-1.3,;22.99,-2.07,;21.66,-1.3,;20.32,-2.07,;20.32,-3.61,;18.99,-4.38,;18.99,-5.92,;17.66,-6.69,;16.12,-6.69,;17.66,-8.23,;16.52,-9.26,;17.15,-10.66,;18.67,-10.5,;18.99,-9,;20.32,-8.23,;21.09,-6.9,;21.66,-9,;21.66,-10.54,;20.32,-11.31,;20.32,-12.85,;18.99,-13.62,;18.99,-15.16,;17.66,-15.93,;20.32,-15.93,;22.99,-8.23,;24.33,-9,;24.33,-10.54,;25.66,-8.23,;26.99,-9,;26.99,-10.54,;25.66,-11.31,;25.66,-12.85,;26.99,-13.62,;26.99,-15.16,;28.33,-12.85,;28.33,-11.31,;25.66,-6.69,;26.99,-5.92,;26.99,-4.38,;28.33,-6.69,;29.66,-5.92,;30.99,-6.69,;30.99,-8.23,;32.33,-5.92,;33.66,-6.69,;33.66,-8.23,;34.99,-9,;34.99,-10.54,;36.33,-11.31,;36.33,-12.85,;37.66,-10.54,;32.33,-4.38,;33.66,-3.61,;34.99,-4.38,;33.66,-2.07,;32.33,-1.3,;32.33,.24,;33.66,1.01,;30.99,1.01,;30.99,2.55,;32.33,3.32,;32.33,4.86,;33.66,2.55,;29.66,.24,;28.33,1.01,;28.33,2.55,;26.99,.24,;25.81,1.23,;26.08,2.75,;27.53,3.27,;27.8,4.79,;26.99,-1.3,;25.66,-2.07,;25.66,-3.61,;28.33,-8.23,;29.66,-9,;28.33,-9.77,;17.66,-3.61,;17.66,-2.07,;16.32,-4.38,;14.99,-3.61,;14.99,-2.07,;13.66,-1.3,;12.26,-1.93,;11.23,-.79,;11.99,.54,;11.51,2,;12.54,3.15,;14.05,2.83,;14.53,1.37,;13.5,.22,;13.66,-4.38,;13.66,-5.92,;12.12,-3.61,;10.78,-4.38,;10.78,-5.92,;9.45,-6.69,;9.45,-8.23,;8.11,-9,;10.78,-9,;9.45,-3.61,;9.45,-2.07,;7.91,-4.38,;6.57,-3.61,;6.57,-2.07,;5.24,-1.3,;7.91,-1.3,;5.24,-4.38,;3.91,-3.61,;5.24,-5.92,)| Show InChI InChI=1S/C105H160N30O26S4/c1-53(2)42-70-86(144)118-50-80(138)119-64(24-16-36-114-103(108)109)90(148)133-83(55(5)6)100(158)130-73(45-58-28-30-60(136)31-29-58)93(151)124-69(26-18-38-116-105(112)113)101(159)135-39-19-27-78(135)99(157)132-77(98(156)128-74(46-59-49-117-63-23-15-14-22-61(59)63)95(153)121-66(32-33-79(107)137)91(149)134-84(56(7)8)102(160)161)52-165-164-51-76(97(155)123-68(35-41-163-10)88(146)126-70)131-87(145)65(25-17-37-115-104(110)111)120-92(150)71(43-54(3)4)127-89(147)67(34-40-162-9)122-96(154)75(48-82(141)142)129-94(152)72(44-57-20-12-11-13-21-57)125-85(143)62(106)47-81(139)140/h11-15,20-23,28-31,49,53-56,62,64-78,83-84,117,136H,16-19,24-27,32-48,50-52,106H2,1-10H3,(H2,107,137)(H,118,144)(H,119,138)(H,120,150)(H,121,153)(H,122,154)(H,123,155)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,156)(H,129,152)(H,130,158)(H,131,145)(H,132,157)(H,133,148)(H,134,149)(H,139,140)(H,141,142)(H,160,161)(H4,108,109,114)(H4,110,111,115)(H4,112,113,116) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 98: 7564-9 (2001)
Article DOI: 10.1073/pnas.121170598
BindingDB Entry DOI: 10.7270/Q2RJ4H14 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)Show SMILES C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38+,39+,40-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand |
J Med Chem 39: 1767-70 (1996)
Article DOI: 10.1021/jm960054c
BindingDB Entry DOI: 10.7270/Q2BK1BDG |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049481
((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)Show SMILES CC(C)(N)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O Show InChI InChI=1S/C29H31N7O2/c1-29(2,30)17-26(37)31-24-16-15-21-7-3-6-10-25(21)36(28(24)38)18-19-11-13-20(14-12-19)22-8-4-5-9-23(22)27-32-34-35-33-27/h3-14,24H,15-18,30H2,1-2H3,(H,31,37)(H,32,33,34,35)/t24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand |
J Med Chem 39: 1767-70 (1996)
Article DOI: 10.1021/jm960054c
BindingDB Entry DOI: 10.7270/Q2BK1BDG |
More data for this
Ligand-Target Pair | |
Melanin-concentrating hormone receptor 2
(Homo sapiens (Human)) | BDBM85790
(Salmon MCH)Show SMILES CSCCC(NC(=O)C(NC(=O)C(N)CC(O)=O)C(C)O)C(=O)NC(CCCN=C(N)N)C(=O)NC1CSSCC(NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(NC(=O)C(CCSC)NC1=O)C(C)C)C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)C)C(O)=O |(16.32,3.32,;17.66,2.55,;18.99,3.32,;18.99,4.86,;20.32,5.63,;20.32,7.17,;21.66,7.94,;22.99,7.17,;21.66,9.48,;22.99,10.25,;22.99,11.79,;21.66,12.56,;24.33,12.56,;25.66,11.79,;24.33,14.1,;25.66,14.87,;25.66,16.41,;26.99,14.1,;20.32,10.25,;18.99,9.48,;20.32,11.79,;21.66,4.86,;22.99,5.63,;21.66,3.32,;22.99,2.55,;24.33,3.32,;24.33,4.86,;25.66,5.63,;25.66,7.17,;26.99,7.94,;26.99,9.48,;28.33,7.17,;22.99,1.01,;21.66,.24,;24.33,.24,;24.33,-1.3,;22.99,-2.07,;21.66,-1.3,;20.32,-2.07,;20.32,-3.61,;18.99,-4.38,;18.99,-5.92,;17.66,-6.69,;16.12,-6.69,;17.66,-8.23,;16.52,-9.26,;17.15,-10.66,;18.67,-10.5,;18.99,-9,;20.32,-8.23,;21.09,-6.9,;21.66,-9,;21.66,-10.54,;20.32,-11.31,;20.32,-12.85,;18.99,-13.62,;18.99,-15.16,;17.66,-15.93,;20.32,-15.93,;22.99,-8.23,;24.33,-9,;24.33,-10.54,;25.66,-8.23,;26.99,-9,;26.99,-10.54,;25.66,-11.31,;25.66,-12.85,;26.99,-13.62,;26.99,-15.16,;28.33,-12.85,;28.33,-11.31,;25.66,-6.69,;26.99,-5.92,;26.99,-4.38,;28.33,-6.69,;29.66,-5.92,;30.99,-6.69,;30.99,-8.23,;32.33,-5.92,;33.66,-6.69,;33.66,-8.23,;34.99,-9,;34.99,-10.54,;36.33,-11.31,;36.33,-12.85,;37.66,-10.54,;32.33,-4.38,;33.66,-3.61,;34.99,-4.38,;33.66,-2.07,;32.33,-1.3,;32.33,.24,;33.66,1.01,;30.99,1.01,;29.66,.24,;28.33,1.01,;28.33,2.55,;26.99,.24,;25.81,1.23,;26.08,2.75,;27.53,3.27,;27.8,4.79,;26.99,-1.3,;25.66,-2.07,;25.66,-3.61,;30.99,2.55,;32.33,3.32,;29.66,3.32,;28.33,-8.23,;29.66,-9,;28.33,-9.77,;17.66,-3.61,;17.66,-2.07,;16.32,-4.38,;14.99,-3.61,;14.99,-2.07,;13.66,-1.3,;12.26,-1.93,;11.23,-.79,;11.99,.54,;11.51,2,;12.54,3.15,;14.05,2.83,;14.53,1.37,;13.5,.22,;13.66,-4.38,;13.66,-5.92,;12.12,-3.61,;10.78,-4.38,;10.78,-5.92,;9.45,-6.69,;9.45,-8.23,;8.11,-9,;10.78,-9,;9.45,-3.61,;9.45,-2.07,;7.91,-4.38,;6.57,-3.61,;6.57,-2.07,;5.24,-1.3,;7.91,-1.3,;5.24,-4.38,;3.91,-3.61,;5.24,-5.92,)| Show InChI InChI=1S/C89H139N27O24S4/c1-43(2)67-82(135)101-40-64(119)102-53(18-12-30-97-87(91)92)74(127)113-68(44(3)4)83(136)109-59(36-47-22-24-49(118)25-23-47)77(130)107-58(20-14-32-99-89(95)96)85(138)116-33-15-21-63(116)81(134)111-62(80(133)108-60(37-48-39-100-52-17-11-10-16-50(48)52)78(131)104-55(26-27-65(120)121)75(128)114-69(45(5)6)86(139)140)42-144-143-41-61(79(132)105-57(29-35-142-9)76(129)112-67)110-72(125)54(19-13-31-98-88(93)94)103-73(126)56(28-34-141-8)106-84(137)70(46(7)117)115-71(124)51(90)38-66(122)123/h10-11,16-17,22-25,39,43-46,51,53-63,67-70,100,117-118H,12-15,18-21,26-38,40-42,90H2,1-9H3,(H,101,135)(H,102,119)(H,103,126)(H,104,131)(H,105,132)(H,106,137)(H,107,130)(H,108,133)(H,109,136)(H,110,125)(H,111,134)(H,112,129)(H,113,127)(H,114,128)(H,115,124)(H,120,121)(H,122,123)(H,139,140)(H4,91,92,97)(H4,93,94,98)(H4,95,96,99) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 437 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 98: 7564-9 (2001)
Article DOI: 10.1073/pnas.121170598
BindingDB Entry DOI: 10.7270/Q2RJ4H14 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049480
(3-Amino-3-methyl-N-{(S)-2-oxo-1-[2'-(1H-tetrazol-5...)Show SMILES CC(C)(N)CC(=O)N[C@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O Show InChI InChI=1S/C29H31N7O2/c1-29(2,30)17-26(37)31-24-16-15-21-7-3-6-10-25(21)36(28(24)38)18-19-11-13-20(14-12-19)22-8-4-5-9-23(22)27-32-34-35-33-27/h3-14,24H,15-18,30H2,1-2H3,(H,31,37)(H,32,33,34,35)/t24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand |
J Med Chem 39: 1767-70 (1996)
Article DOI: 10.1021/jm960054c
BindingDB Entry DOI: 10.7270/Q2BK1BDG |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267262
(CHEMBL501253)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC(=O)CCCCCCCBr)NC(=O)[C@H](CO)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:171.183,157.163,150.152,111.120,107.109,78.87,60.67,45.52,36.43,17.17,89.96,131.140,4.4,wD:163.171,141.149,122.129,69.76,54.58,29.29,22.21,8.13,212.216,224.230,228.233,182.199,198.205,98.105,(40.77,-32.54,;40.37,-34.04,;41.48,-35.11,;38.9,-34.45,;38.5,-35.92,;37.01,-36.31,;35.9,-35.25,;36.28,-33.75,;34.41,-35.66,;34.03,-37.15,;35.12,-38.23,;34.73,-39.72,;35.84,-40.79,;35.44,-42.29,;33.31,-34.58,;31.84,-34.99,;31.44,-36.47,;30.74,-33.9,;31.12,-32.42,;29.25,-34.31,;28.16,-33.24,;28.54,-31.74,;26.67,-33.65,;26.37,-35.17,;24.68,-35.08,;24.26,-33.45,;25.66,-32.54,;25.86,-31.02,;27.27,-30.41,;24.68,-30.01,;23.25,-30.62,;22.38,-29.18,;23.48,-27.91,;25.01,-28.54,;26.37,-27.86,;27.68,-28.7,;26.46,-26.33,;27.84,-25.64,;29.13,-26.47,;29.05,-28,;30.34,-28.84,;30.26,-30.36,;25.16,-25.49,;25.25,-23.93,;23.97,-23.1,;26.62,-23.24,;27.91,-24.1,;29.3,-23.39,;30.57,-24.22,;31.96,-23.53,;33.24,-24.36,;26.7,-21.7,;28.06,-21,;29.35,-21.85,;28.14,-19.45,;26.86,-18.62,;25.51,-19.29,;29.5,-18.77,;29.6,-17.22,;28.32,-16.38,;30.96,-16.52,;32.25,-17.38,;33.64,-16.67,;34.91,-17.52,;34.86,-19,;36.3,-16.81,;31.04,-14.98,;32.4,-14.28,;33.7,-15.13,;32.48,-12.73,;31.21,-11.9,;31.3,-10.38,;30,-9.54,;30.08,-8.01,;28.79,-7.15,;33.84,-12.05,;33.93,-10.5,;32.66,-9.66,;35.3,-9.81,;36.6,-10.66,;37.97,-9.95,;39.25,-10.8,;40.65,-10.09,;41.91,-10.92,;41.83,-12.45,;43.3,-10.23,;35.38,-8.29,;34.09,-7.44,;32.73,-8.12,;34.17,-5.91,;35.54,-5.22,;36.82,-6.05,;38.22,-5.34,;38.3,-3.79,;39.48,-6.18,;32.9,-5.03,;32.94,-3.49,;34.33,-2.78,;31.65,-2.63,;30.29,-3.33,;29.01,-2.49,;27.61,-3.19,;27.53,-4.74,;26.33,-2.36,;31.73,-1.09,;30.44,-.25,;29.07,-.93,;30.52,1.27,;29.24,2.11,;27.85,1.41,;27.77,-.11,;26.58,2.25,;26.67,3.8,;25.37,4.63,;25.45,6.15,;24.16,7.01,;24.23,8.53,;25.6,9.21,;22.94,9.41,;25.19,1.54,;23.91,2.37,;24.01,3.93,;22.53,1.68,;22.45,.15,;21.08,-.53,;21,-2.09,;22.3,-2.93,;19.64,-2.77,;21.25,2.51,;19.88,1.8,;19.78,.29,;18.59,2.65,;18.68,4.18,;20.04,4.88,;20.27,6.39,;21.78,6.63,;22.49,5.31,;21.42,4.2,;17.22,1.96,;15.92,2.78,;16.01,4.34,;14.53,2.09,;14.44,.56,;15.75,-.29,;15.68,-1.81,;14.3,-2.48,;16.97,-2.66,;13.25,2.93,;11.87,2.24,;11.79,.7,;10.6,3.07,;10.73,4.59,;9.12,5.02,;8.24,3.61,;9.29,2.31,;9.02,.81,;10.24,-.12,;7.6,.2,;6.38,1.13,;6.58,2.65,;7.41,-1.33,;6.05,-2.04,;4.75,-1.22,;6,-3.58,;7.3,-4.4,;8.66,-3.69,;9.96,-4.5,;8.71,-2.15,;4.63,-4.3,;4.57,-5.84,;5.88,-6.66,;3.22,-6.57,;1.92,-5.75,;1.97,-4.21,;3.32,-3.5,;3.37,-1.96,;2.07,-1.16,;.71,-1.88,;.67,-3.4,;3.17,-8.11,;1.82,-8.83,;.51,-8.03,;1.77,-10.37,;3.08,-11.18,;4.43,-10.45,;5.74,-11.25,;5.7,-12.79,;7.47,-10.42,;9.06,-11.51,;10.79,-10.67,;12.38,-11.76,;14.11,-10.93,;15.7,-12.01,;17.44,-11.18,;19.02,-12.26,;.42,-11.1,;-1.12,-11.09,;-1.89,-9.75,;-1.91,-12.43,;-1.14,-13.77,;.41,-13.77,;-3.45,-12.42,;-4.23,-13.75,;-3.46,-15.09,;-5.77,-13.75,;-6.55,-15.08,;31.91,1.97,;32,3.53,;33.18,1.14,;39.6,-37.01,;39.22,-38.49,;41.09,-36.6,;42.18,-37.68,;41.8,-39.17,;40.31,-39.58,;39.93,-41.08,;38.44,-41.48,;41.03,-42.15,;43.67,-37.27,;44.05,-35.79,;44.77,-38.36,;44.64,-40.03,;46.19,-40.66,;47.28,-39.39,;46.25,-38.22,;46.83,-36.79,;45.88,-35.59,;48.36,-36.58,;48.93,-35.15,;50.46,-34.95,;51.41,-36.14,;52.93,-35.93,;53.88,-37.13,;55.41,-36.92,;55.98,-35.49,;56.36,-38.13,;47.98,-33.94,;46.46,-34.13,;48.56,-32.52,)| Show InChI InChI=1S/C149H248BrN47O42/c1-80(2)69-99(131(222)184-97(48-54-114(159)204)143(234)194-65-27-42-109(194)140(231)185-98(146(237)238)39-26-64-169-149(164)165)186-124(215)86(33-15-20-58-151)173-120(211)83(7)171-138(229)107-40-29-67-196(107)145(236)110-43-30-68-197(110)142(233)96(36-18-23-61-154)183-123(214)88(35-17-22-60-153)177-136(227)104(76-199)190-129(220)94(49-55-116(206)207)179-121(212)87(34-16-21-59-152)174-122(213)89(37-24-62-167-147(160)161)175-125(216)91(45-51-111(156)201)178-127(218)93(47-53-113(158)203)182-141(232)119(82(5)6)193-130(221)90(38-25-63-168-148(162)163)176-126(217)92(46-52-112(157)202)180-134(225)102(72-85-74-166-79-170-85)189-128(219)95(50-56-117(208)209)181-139(230)108-41-28-66-195(108)144(235)105(77-200)191-132(223)100(70-81(3)4)187-133(224)101(71-84-31-12-11-13-32-84)188-137(228)106(192-135(226)103(75-198)172-115(205)73-155)78-239-118(210)44-14-9-8-10-19-57-150/h11-13,31-32,74,79-83,86-110,119,198-200H,8-10,14-30,33-73,75-78,151-155H2,1-7H3,(H2,156,201)(H2,157,202)(H2,158,203)(H2,159,204)(H,166,170)(H,171,229)(H,172,205)(H,173,211)(H,174,213)(H,175,216)(H,176,217)(H,177,227)(H,178,218)(H,179,212)(H,180,225)(H,181,230)(H,182,232)(H,183,214)(H,184,222)(H,185,231)(H,186,215)(H,187,224)(H,188,228)(H,189,219)(H,190,220)(H,191,223)(H,192,226)(H,193,221)(H,206,207)(H,208,209)(H,237,238)(H4,160,161,167)(H4,162,163,168)(H4,164,165,169)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422313
(CHEMBL2310891)Show SMILES CCCCCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:181.185,226.232,188.193,57.59,70.71,40.40,107.109,160.162,145.147,125.127,214.218,18.20,197.201,230.235,wD:100.102,48.48,14.14,154.156,29.28,61.62,169.171,80.82,116.118,136.138,89.91,206.210,192.197,(60.62,-14.96,;59.09,-15.07,;58.22,-13.8,;56.69,-13.91,;55.82,-12.63,;54.29,-12.74,;53.42,-11.47,;51.89,-11.58,;51.02,-10.3,;49.49,-10.41,;48.63,-9.13,;49.3,-7.75,;47.09,-9.25,;46.23,-7.97,;44.69,-8.08,;44.02,-9.47,;44.88,-10.74,;46.42,-10.63,;44.21,-12.13,;42.67,-12.24,;41.81,-10.96,;45.07,-13.4,;44.4,-14.79,;42.86,-14.9,;45.26,-16.06,;44.59,-17.45,;43.83,-6.8,;44.5,-5.42,;42.29,-6.92,;41.43,-5.64,;42.1,-4.25,;41.24,-2.98,;41.91,-1.59,;41.05,-.32,;39.51,-.43,;38.84,-1.81,;39.7,-3.09,;39.89,-5.75,;39.22,-7.14,;39.03,-4.47,;37.49,-4.59,;36.82,-5.97,;35.28,-6.08,;34.61,-7.47,;34.42,-4.81,;36.63,-3.31,;37.3,-1.92,;35.09,-3.42,;34.23,-2.14,;34.9,-.76,;34.04,.52,;32.69,-2.26,;31.83,-.98,;32.02,-3.64,;32.75,-5,;31.68,-6.11,;30.29,-5.44,;30.5,-3.91,;29.39,-2.84,;29.76,-1.35,;27.91,-3.27,;26.8,-2.2,;27.17,-.71,;26.06,.36,;26.43,1.86,;27.91,2.28,;25.33,2.92,;25.33,-2.63,;24.96,-4.12,;24.22,-1.56,;22.74,-1.99,;22.37,-3.48,;20.89,-3.91,;20.36,-5.36,;18.82,-5.31,;18.4,-3.83,;19.67,-2.96,;21.63,-.92,;22,.57,;20.15,-1.35,;19.04,-.28,;19.41,1.21,;20.89,1.64,;21.26,3.14,;20.15,4.2,;22.74,3.56,;17.56,-.71,;17.19,-2.2,;16.45,.36,;14.97,-.07,;13.86,1,;14.23,2.5,;13.12,3.56,;13.49,5.06,;12.38,6.13,;12.75,7.62,;10.9,5.7,;14.6,-1.56,;15.71,-2.63,;13.12,-1.99,;12.01,-.92,;12.38,.57,;11.27,1.64,;13.32,1.79,;10.53,-1.35,;10.16,-2.84,;9.42,-.28,;7.94,-.71,;7.57,-2.2,;6.09,-2.63,;5.72,-4.12,;6.83,-5.19,;4.24,-4.55,;6.83,.36,;7.2,1.86,;5.35,-.07,;4.24,1,;4.61,2.5,;6.09,2.92,;6.46,4.42,;5.35,5.49,;7.94,4.85,;2.76,.57,;1.65,1.64,;2.39,-.92,;.91,-1.35,;.54,-2.84,;-.94,-3.27,;-1.31,-4.76,;-.2,-5.83,;-.57,-7.33,;.54,-8.4,;-2.05,-7.75,;-.2,-.28,;.17,1.21,;-1.68,-.71,;-2.79,.36,;-2.42,1.86,;-.94,2.28,;-.57,3.78,;.91,4.2,;1.28,5.7,;-4.27,-.07,;-4.64,-1.56,;-5.38,1,;-6.86,.57,;-7.23,-.92,;-8.71,-1.35,;-9.08,-2.84,;-7.97,-3.91,;-10.55,-3.27,;-7.97,1.64,;-7.6,3.14,;-9.45,1.21,;-10.55,2.28,;-10.18,3.78,;-11.29,4.85,;-12.03,1.86,;-12.4,.36,;-13.14,2.92,;-14.62,2.5,;-14.99,1,;-16.58,.02,;-13.43,.07,;-13.99,-.93,;-13.69,-2.24,;-15.73,3.56,;-15.36,5.06,;-16.94,2.48,;-18.63,1.86,;-19.61,1.49,;-20.17,2.28,;-21.65,1.86,;-22.76,2.92,;-24.24,2.5,;-18.26,.26,;-19.79,.15,;-17.39,-1.02,;-15.85,-1.07,;-15.43,-2.55,;-16.7,-3.41,;-18.06,-2.63,;-19.4,-2.89,;-20.41,-1.73,;-19.89,-4.35,;-19.01,-5.61,;-19.93,-6.84,;-21.39,-6.34,;-21.37,-4.8,;-22.6,-3.88,;-24.01,-4.48,;-22.41,-2.35,;-23.64,-1.43,;-23.46,.1,;-25.06,-2.03,;-25.25,-3.56,;-26.29,-1.11,;-27.71,-1.71,;-27.89,-3.24,;-26.66,-4.16,;-26.85,-5.69,;-25.62,-6.62,;-25.8,-8.15,;-28.94,-.79,;-28.76,.74,;-30.36,-1.39,;-31.59,-.47,;-31.4,1.06,;-32.64,1.99,;-34.05,1.38,;-32.45,3.52,;-33.01,-1.07,;-33.19,-2.6,;-34.24,-.15,;-35.65,-.75,;-35.84,-2.28,;-37.25,-2.88,;-37.44,-4.41,;-38.86,-5.02,;-36.21,-5.34,;-36.89,.17,;-36.7,1.7,;-38.3,-.43,;-38.65,-1.93,;-40.18,-2.07,;-40.78,-.65,;-39.62,.36,;-39.76,1.89,;-38.5,2.78,;-41.16,2.54,;-41.29,4.08,;-42.69,4.72,;-42.83,6.26,;-44.23,6.91,;-44.36,8.44,;-43.1,9.33,;-43.24,10.86,;-41.71,8.68,;-40.03,4.96,;-38.64,4.31,;-40.17,6.5,)| Show InChI InChI=1S/C152H255N47O42/c1-9-10-11-12-13-14-15-19-48-121(212)241-81-109(194-138(228)106(78-200)174-118(207)76-157)140(230)190-104(74-87-35-17-16-18-36-87)136(226)189-103(73-84(4)5)135(225)193-108(80-202)147(237)197-69-32-45-111(197)142(232)183-98(54-60-120(210)211)131(221)191-105(75-88-77-168-82-172-88)137(227)182-95(50-56-115(159)204)129(219)178-93(42-29-66-170-151(164)165)133(223)195-122(85(6)7)144(234)184-96(51-57-116(160)205)130(220)180-94(49-55-114(158)203)128(218)177-92(41-28-65-169-150(162)163)125(215)176-90(38-21-25-62-154)124(214)181-97(53-59-119(208)209)132(222)192-107(79-201)139(229)179-91(39-22-26-63-155)126(216)185-99(40-23-27-64-156)145(235)199-71-34-47-113(199)148(238)198-70-33-44-110(198)141(231)173-86(8)123(213)175-89(37-20-24-61-153)127(217)188-102(72-83(2)3)134(224)186-100(52-58-117(161)206)146(236)196-68-31-46-112(196)143(233)187-101(149(239)240)43-30-67-171-152(166)167/h16-18,35-36,77,82-86,89-113,122,200-202H,9-15,19-34,37-76,78-81,153-157H2,1-8H3,(H2,158,203)(H2,159,204)(H2,160,205)(H2,161,206)(H,168,172)(H,173,231)(H,174,207)(H,175,213)(H,176,215)(H,177,218)(H,178,219)(H,179,229)(H,180,220)(H,181,214)(H,182,227)(H,183,232)(H,184,234)(H,185,216)(H,186,224)(H,187,233)(H,188,217)(H,189,226)(H,190,230)(H,191,221)(H,192,222)(H,193,225)(H,194,228)(H,195,223)(H,208,209)(H,210,211)(H,239,240)(H4,162,163,169)(H4,164,165,170)(H4,166,167,171)/t86-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267261
(CHEMBL525994)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC(=O)CC12CC3CC(CC(C3)C1)C2)NC(=O)[C@H](CO)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:171.183,157.163,150.152,111.120,107.109,78.87,60.67,45.52,36.43,17.17,89.96,131.140,4.4,wD:163.171,141.149,122.129,69.76,54.58,29.29,22.21,8.13,215.222,227.236,231.239,182.205,201.211,98.105,TLB:187:188:191:195.193.194,THB:196:194:191:197.188.189,196:188:191:195.193.194,193:192:189:195.194.196,193:194:191.192.197:189,(41.29,-28.01,;41,-29.53,;42.17,-30.52,;39.55,-30.03,;39.25,-31.53,;37.79,-32.01,;36.61,-31.03,;36.89,-29.51,;35.15,-31.53,;34.87,-33.05,;36.03,-34.04,;35.74,-35.56,;36.91,-36.56,;36.61,-38.08,;33.99,-30.53,;32.54,-31.03,;32.25,-32.53,;31.37,-30.02,;31.67,-28.52,;29.92,-30.52,;28.76,-29.52,;29.04,-28.01,;27.3,-30.03,;27.1,-31.56,;25.41,-31.58,;24.88,-29.99,;26.22,-28.99,;26.32,-27.46,;27.69,-26.76,;25.08,-26.53,;23.69,-27.23,;22.73,-25.85,;23.74,-24.51,;25.32,-25.04,;26.63,-24.27,;27.99,-25.02,;26.62,-22.74,;27.95,-21.96,;29.29,-22.7,;29.3,-24.23,;30.65,-24.99,;30.67,-26.52,;25.26,-21.99,;25.25,-20.42,;23.93,-19.68,;26.57,-19.65,;27.92,-20.42,;29.26,-19.63,;30.58,-20.37,;31.92,-19.59,;33.25,-20.34,;26.55,-18.11,;27.87,-17.32,;29.21,-18.09,;27.85,-15.77,;26.52,-15.03,;25.21,-15.78,;29.16,-15,;29.16,-13.45,;27.82,-12.7,;30.47,-12.67,;31.82,-13.44,;33.15,-12.64,;34.48,-13.4,;34.52,-14.89,;35.82,-12.61,;30.45,-11.12,;31.76,-10.34,;33.11,-11.1,;31.74,-8.79,;30.42,-8.04,;30.41,-6.51,;29.06,-5.76,;29.04,-4.23,;27.7,-3.46,;33.06,-8.02,;33.04,-6.47,;31.72,-5.71,;34.37,-5.69,;35.71,-6.45,;37.04,-5.66,;38.37,-6.42,;39.72,-5.63,;41.03,-6.37,;41.05,-7.9,;42.38,-5.59,;34.35,-4.17,;33,-3.4,;31.69,-4.17,;32.98,-1.87,;34.31,-1.09,;35.64,-1.84,;36.98,-1.04,;36.97,.5,;38.3,-1.8,;31.66,-1.08,;31.6,.46,;32.94,1.26,;30.26,1.23,;28.94,.45,;27.61,1.21,;26.27,.41,;26.29,-1.14,;24.94,1.16,;30.24,2.77,;28.9,3.53,;27.57,2.76,;28.88,5.05,;27.55,5.81,;26.21,5.02,;26.22,3.5,;24.89,5.77,;24.87,7.32,;23.52,8.07,;23.5,9.59,;22.16,10.38,;22.14,11.89,;23.45,12.67,;20.79,12.68,;23.55,4.98,;22.21,5.73,;22.21,7.29,;20.89,4.95,;20.9,3.42,;19.58,2.65,;19.6,1.08,;20.95,.33,;18.28,.31,;19.55,5.69,;18.23,4.9,;18.23,3.38,;16.89,5.66,;16.88,7.18,;18.19,7.98,;18.32,9.5,;19.82,9.84,;20.6,8.56,;19.61,7.39,;15.57,4.87,;14.22,5.61,;14.21,7.17,;12.88,4.84,;12.89,3.3,;14.25,2.54,;14.27,1.02,;12.95,.26,;15.62,.25,;11.55,5.59,;10.21,4.81,;10.23,3.27,;8.89,5.56,;8.93,7.08,;7.29,7.4,;6.5,5.94,;7.64,4.71,;7.47,3.2,;8.74,2.35,;6.08,2.5,;4.81,3.35,;4.91,4.87,;5.99,.96,;4.62,.28,;3.34,1.13,;4.53,-1.26,;5.82,-2.11,;7.19,-1.43,;8.47,-2.26,;7.27,.11,;3.15,-1.94,;3.05,-3.48,;4.34,-4.33,;1.68,-4.17,;.4,-3.32,;.49,-1.79,;1.85,-1.11,;1.94,.43,;.66,1.26,;-.71,.57,;-.79,-.95,;1.6,-5.71,;.23,-6.4,;-1.06,-5.57,;.14,-7.94,;1.43,-8.78,;2.8,-8.08,;4.09,-8.91,;4.01,-10.45,;5.84,-8.12,;7.4,-9.26,;6.88,-10.96,;8.38,-12.05,;8.78,-14.2,;9.47,-12.38,;11.07,-11.38,;10.54,-9.42,;9.85,-11.08,;9.01,-8.28,;7.87,-11.21,;-1.23,-8.64,;-2.76,-8.59,;-3.5,-7.23,;-3.58,-9.91,;-2.84,-11.26,;-1.29,-11.31,;-5.12,-9.87,;-5.93,-11.18,;-5.19,-12.53,;-7.47,-11.13,;-8.28,-12.44,;30.21,5.84,;30.2,7.4,;31.54,5.1,;40.42,-32.54,;40.13,-34.05,;41.87,-32.04,;43.04,-33.04,;42.75,-34.56,;41.29,-35.06,;41.01,-36.58,;39.55,-37.08,;42.17,-37.58,;44.5,-32.54,;44.78,-31.04,;45.66,-33.55,;45.64,-35.22,;47.23,-35.76,;48.23,-34.42,;47.13,-33.32,;47.62,-31.85,;46.59,-30.72,;49.12,-31.55,;49.61,-30.08,;51.11,-29.78,;52.14,-30.91,;53.65,-30.61,;54.67,-31.74,;56.18,-31.43,;56.66,-29.96,;57.2,-32.58,;48.58,-28.93,;47.07,-29.23,;49.06,-27.48,)| Show InChI InChI=1S/C153H251N47O42/c1-80(2)62-102(134(225)187-100(42-48-117(162)207)146(237)197-58-22-37-112(197)143(234)188-101(149(240)241)34-21-57-172-152(167)168)189-127(218)89(28-11-15-51-154)176-123(214)83(7)174-141(232)110-35-24-60-199(110)148(239)113-38-25-61-200(113)145(236)99(31-14-18-54-157)186-126(217)91(30-13-17-53-156)180-139(230)107(76-202)193-132(223)97(43-49-119(209)210)182-124(215)90(29-12-16-52-155)177-125(216)92(32-19-55-170-150(163)164)178-128(219)94(39-45-114(159)204)181-130(221)96(41-47-116(161)206)185-144(235)122(82(5)6)196-133(224)93(33-20-56-171-151(165)166)179-129(220)95(40-46-115(160)205)183-137(228)105(68-88-74-169-79-173-88)192-131(222)98(44-50-120(211)212)184-142(233)111-36-23-59-198(111)147(238)108(77-203)194-135(226)103(63-81(3)4)190-136(227)104(67-84-26-9-8-10-27-84)191-140(231)109(195-138(229)106(75-201)175-118(208)73-158)78-242-121(213)72-153-69-85-64-86(70-153)66-87(65-85)71-153/h8-10,26-27,74,79-83,85-87,89-113,122,201-203H,11-25,28-73,75-78,154-158H2,1-7H3,(H2,159,204)(H2,160,205)(H2,161,206)(H2,162,207)(H,169,173)(H,174,232)(H,175,208)(H,176,214)(H,177,216)(H,178,219)(H,179,220)(H,180,230)(H,181,221)(H,182,215)(H,183,228)(H,184,233)(H,185,235)(H,186,217)(H,187,225)(H,188,234)(H,189,218)(H,190,227)(H,191,231)(H,192,222)(H,193,223)(H,194,226)(H,195,229)(H,196,224)(H,209,210)(H,211,212)(H,240,241)(H4,163,164,170)(H4,165,166,171)(H4,167,168,172)/t83-,85?,86?,87?,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,153?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422316
(CHEMBL2310888)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O |r,wU:178.182,185.190,97.99,45.45,11.11,151.153,26.25,58.59,166.168,77.79,113.115,133.135,15.17,wD:54.56,67.68,37.37,104.106,157.159,142.144,86.88,122.124,189.194,(52.08,.51,;50.93,-.52,;49.47,-.04,;48.32,-1.07,;46.86,-.6,;45.72,-1.63,;44.25,-1.15,;43.11,-2.18,;43.43,-3.69,;41.64,-1.71,;40.5,-2.74,;39.03,-2.26,;38.71,-.75,;37.25,-.28,;36.1,-1.31,;36.93,1.23,;38.07,2.26,;39.54,1.78,;35.46,1.7,;35.14,3.21,;36.29,4.24,;33.68,3.69,;33.36,5.19,;37.89,-3.29,;38.21,-4.8,;36.42,-2.82,;35.28,-3.85,;35.6,-5.35,;34.45,-6.38,;32.99,-5.91,;31.85,-6.94,;32.17,-8.44,;33.63,-8.92,;34.77,-7.89,;33.81,-3.37,;33.49,-1.86,;32.67,-4.4,;31.21,-3.92,;30.89,-2.42,;29.42,-1.94,;28.28,-2.97,;29.1,-.44,;30.06,-4.95,;30.38,-6.46,;28.6,-4.48,;27.45,-5.51,;27.77,-7.02,;26.63,-8.05,;25.99,-5.03,;24.84,-6.06,;25.67,-3.53,;26.7,-2.38,;25.93,-1.05,;24.42,-1.37,;24.26,-2.9,;22.93,-3.67,;22.93,-5.21,;21.59,-2.9,;20.26,-3.67,;20.26,-5.21,;18.93,-5.98,;18.93,-7.52,;17.59,-8.29,;20.26,-8.29,;18.93,-2.9,;18.93,-1.36,;17.59,-3.67,;16.26,-2.9,;16.26,-1.36,;14.92,-.59,;13.52,-1.22,;12.49,-.07,;13.26,1.26,;14.76,.94,;14.92,-3.67,;14.92,-5.21,;13.59,-2.9,;12.26,-3.67,;12.26,-5.21,;13.59,-5.98,;13.59,-7.52,;12.26,-8.29,;14.92,-8.29,;10.92,-2.9,;10.92,-1.36,;9.59,-3.67,;8.26,-2.9,;8.26,-1.36,;6.92,-.59,;6.92,.95,;8.26,1.72,;8.26,3.26,;9.59,4.03,;6.92,4.03,;6.92,-3.67,;6.92,-5.21,;5.59,-2.9,;4.25,-3.67,;4.25,-5.21,;2.92,-5.98,;5.59,-5.98,;2.92,-2.9,;2.92,-1.36,;1.59,-3.67,;.25,-2.9,;.25,-1.36,;-1.08,-.59,;-1.08,.95,;.25,1.72,;-2.41,1.72,;-1.08,-3.67,;-1.08,-5.21,;-2.41,-2.9,;-3.75,-3.67,;-3.75,-5.21,;-2.41,-5.98,;-2.41,-7.52,;-3.75,-8.29,;-1.08,-8.29,;-5.08,-2.9,;-5.08,-1.36,;-6.41,-3.67,;-7.75,-2.9,;-7.75,-1.36,;-9.08,-.59,;-9.08,.95,;-10.42,1.72,;-10.42,3.26,;-11.75,4.03,;-9.08,4.03,;-9.08,-3.67,;-9.08,-5.21,;-10.42,-2.9,;-11.75,-3.67,;-11.75,-5.21,;-10.42,-5.98,;-10.42,-7.52,;-9.08,-8.29,;-9.08,-9.83,;-13.08,-2.9,;-13.08,-1.36,;-14.42,-3.67,;-15.75,-2.9,;-15.75,-1.36,;-17.08,-.59,;-17.08,.95,;-15.75,1.72,;-18.42,1.72,;-17.08,-3.67,;-17.08,-5.21,;-18.42,-2.9,;-19.75,-3.67,;-19.75,-5.21,;-21.09,-5.98,;-21.09,-2.9,;-21.09,-1.36,;-22.42,-3.67,;-23.75,-2.9,;-23.75,-1.36,;-25.09,-.59,;-25.09,.95,;-26.42,1.72,;-26.42,3.26,;-25.09,-3.67,;-25.09,-5.21,;-26.42,-2.9,;-27.75,-3.67,;-27.75,-5.21,;-26.42,-5.98,;-26.42,-7.52,;-25.09,-8.29,;-25.09,-9.83,;-29.09,-2.9,;-29.09,-1.36,;-30.42,-3.67,;-30.58,-5.2,;-32.09,-5.52,;-32.86,-4.19,;-31.83,-3.04,;-32.15,-1.54,;-31,-.51,;-33.61,-1.06,;-34.86,-1.97,;-36.1,-1.06,;-35.63,.4,;-34.09,.4,;-33.18,1.65,;-31.65,1.49,;-33.81,3.06,;-32.9,4.3,;-31.37,4.14,;-33.53,5.71,;-35.06,5.87,;-32.63,6.95,)| Show InChI InChI=1S/C121H200N38O35/c1-7-8-9-10-14-36-96(171)194-63-86(155-111(185)83(60-160)139-93(166)58-125)113(187)151-81(56-68-26-12-11-13-27-68)109(183)150-80(55-65(2)3)108(182)154-85(62-162)118(192)157-52-23-34-88(157)115(189)147-78(41-46-95(169)170)105(179)152-82(57-69-59-134-64-137-69)110(184)146-75(38-43-91(127)164)103(177)142-73(32-22-51-136-121(132)133)107(181)156-97(66(4)5)116(190)148-76(39-44-92(128)165)104(178)144-74(37-42-90(126)163)102(176)141-72(31-21-50-135-120(130)131)100(174)140-70(28-15-18-47-122)99(173)145-77(40-45-94(167)168)106(180)153-84(61-161)112(186)143-71(29-16-19-48-123)101(175)149-79(30-17-20-49-124)117(191)159-54-25-35-89(159)119(193)158-53-24-33-87(158)114(188)138-67(6)98(129)172/h11-13,26-27,59,64-67,70-89,97,160-162H,7-10,14-25,28-58,60-63,122-125H2,1-6H3,(H2,126,163)(H2,127,164)(H2,128,165)(H2,129,172)(H,134,137)(H,138,188)(H,139,166)(H,140,174)(H,141,176)(H,142,177)(H,143,186)(H,144,178)(H,145,173)(H,146,184)(H,147,189)(H,148,190)(H,149,175)(H,150,183)(H,151,187)(H,152,179)(H,153,180)(H,154,182)(H,155,185)(H,156,181)(H,167,168)(H,169,170)(H4,130,131,135)(H4,132,133,136)/t67-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,97-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM21940
(Ghrelin)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |wU:166.168,203.207,151.153,133.135,67.68,77.79,26.25,113.115,11.11,97.99,178.182,185.190,189.194,wD:194.198,157.159,211.215,227.232,142.144,58.59,45.45,37.37,122.124,86.88,104.106,15.17,223.229,54.56,(58.89,-82.98,;57.56,-82.21,;57.56,-80.67,;56.23,-79.9,;56.23,-78.36,;54.89,-77.59,;54.89,-76.05,;53.56,-75.28,;52.22,-76.05,;53.56,-73.74,;52.22,-72.97,;52.22,-71.43,;53.56,-70.66,;54.89,-71.43,;54.89,-72.97,;56.23,-70.66,;56.23,-69.12,;57.56,-68.35,;57.56,-71.43,;58.89,-70.66,;58.89,-69.12,;60.23,-71.43,;61.56,-70.66,;50.89,-70.66,;50.89,-69.12,;49.56,-71.43,;48.22,-70.66,;46.89,-71.43,;46.89,-72.97,;48.22,-73.74,;48.22,-75.28,;46.89,-76.05,;45.56,-75.28,;45.56,-73.74,;48.22,-69.12,;49.56,-68.35,;46.89,-68.35,;46.89,-66.81,;48.22,-66.04,;48.22,-64.5,;49.56,-63.73,;46.89,-63.73,;45.56,-66.04,;45.56,-64.5,;44.22,-66.81,;42.89,-66.04,;42.89,-64.5,;41.55,-63.73,;41.55,-66.81,;41.55,-68.35,;40.22,-66.04,;40.06,-64.51,;38.55,-64.19,;37.78,-65.52,;38.81,-66.67,;38.49,-68.17,;39.64,-69.2,;37.03,-68.65,;35.88,-67.62,;36.2,-66.11,;35.06,-65.08,;35.38,-63.58,;34.24,-62.54,;36.85,-63.1,;34.42,-68.09,;34.1,-69.6,;33.28,-67.06,;31.81,-67.54,;31.49,-69.05,;30.03,-69.52,;28.78,-68.62,;27.53,-69.52,;28.01,-70.99,;29.55,-70.99,;30.67,-66.51,;29.2,-66.99,;30.99,-65,;29.84,-63.97,;28.38,-64.45,;27.23,-63.42,;25.77,-63.89,;24.62,-62.86,;25.45,-65.4,;30.16,-62.47,;31.63,-61.99,;29.02,-61.44,;29.34,-59.93,;30.8,-59.45,;31.12,-57.95,;32.59,-57.47,;32.91,-55.96,;34.37,-55.49,;34.69,-53.98,;35.52,-56.52,;28.19,-58.9,;26.73,-59.37,;28.51,-57.39,;27.37,-56.36,;25.9,-56.84,;24.76,-55.81,;25.58,-58.34,;27.69,-54.86,;29.15,-54.38,;26.54,-53.83,;26.87,-52.32,;28.33,-51.84,;28.65,-50.34,;30.11,-49.86,;30.43,-48.35,;31.26,-50.89,;25.72,-51.29,;24.26,-51.76,;26.04,-49.78,;24.9,-48.75,;23.43,-49.23,;22.29,-48.2,;20.82,-48.67,;19.68,-47.64,;20.5,-50.18,;25.22,-47.25,;26.68,-46.77,;24.07,-46.21,;24.39,-44.71,;25.86,-44.23,;26.18,-42.73,;27.64,-42.25,;27.96,-40.74,;29.43,-40.27,;29.75,-38.76,;30.57,-41.3,;23.25,-43.68,;21.78,-44.15,;23.57,-42.17,;22.42,-41.14,;20.96,-41.62,;19.81,-40.59,;18.35,-41.06,;17.21,-40.03,;15.74,-40.51,;22.74,-39.63,;24.21,-39.16,;21.6,-38.6,;21.92,-37.1,;23.38,-36.62,;23.7,-35.12,;25.17,-34.64,;25.49,-33.13,;26.31,-35.67,;20.77,-36.07,;19.31,-36.54,;21.1,-34.56,;19.95,-33.53,;18.49,-34.01,;17.34,-32.98,;20.27,-32.02,;21.74,-31.55,;19.13,-30.99,;19.45,-29.49,;20.91,-29.01,;21.23,-27.5,;22.7,-27.03,;23.02,-25.52,;24.48,-25.05,;18.3,-28.46,;16.84,-28.93,;18.62,-26.95,;17.48,-25.92,;16.01,-26.4,;14.87,-25.37,;13.4,-25.84,;12.26,-24.81,;10.79,-25.29,;17.8,-24.41,;19.26,-23.94,;16.65,-23.38,;15.15,-23.7,;14.38,-22.37,;15.41,-21.22,;16.81,-21.85,;18.15,-21.08,;19.48,-21.85,;18.15,-19.54,;16.9,-18.64,;17.38,-17.17,;18.92,-17.17,;19.39,-18.64,;20.86,-19.11,;21.18,-20.62,;22,-18.08,;21.68,-16.57,;20.22,-16.1,;22.83,-15.54,;24.29,-16.02,;22.51,-14.04,;23.65,-13.01,;25.12,-13.48,;26.26,-12.45,;27.73,-12.93,;28.87,-11.9,;30.33,-12.37,;23.33,-11.5,;21.87,-11.03,;24.48,-10.47,;24.16,-8.96,;22.69,-8.49,;21.66,-7.34,;20.15,-7.66,;22.14,-5.88,;25.3,-7.93,;26.76,-8.41,;24.98,-6.43,;26.12,-5.4,;27.59,-5.87,;28.73,-4.84,;30.2,-5.32,;30.52,-6.82,;31.34,-4.29,;25.8,-3.89,;24.34,-3.41,;26.95,-2.86,;28.46,-3.18,;29.23,-1.85,;28.19,-.7,;26.79,-1.33,;25.45,-.56,;24.12,-1.33,;25.45,.98,;26.79,1.75,;28.12,.98,;29.46,1.75,;30.79,.98,;32.12,1.75,;33.46,.98,;34.79,1.75,;33.46,-.56,;26.79,3.29,;28.12,4.06,;25.45,4.06,)| Show InChI InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267264
(CHEMBL504776)Show SMILES CCCCCCCC(=O)NC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:26.25,45.45,54.56,86.88,97.99,122.124,142.144,157.159,166.168,189.194,113.115,67.68,203.207,wD:37.37,58.59,77.79,133.135,151.153,178.182,185.190,194.198,211.215,223.229,227.232,11.11,15.17,104.106,(9.83,-8.53,;9.87,-6.99,;8.56,-6.19,;7.2,-6.92,;5.89,-6.11,;4.54,-6.84,;3.23,-6.03,;1.87,-6.76,;1.83,-8.3,;.56,-5.95,;-.79,-6.68,;-2.1,-5.87,;-3.46,-6.61,;-4.99,-6.6,;-5.76,-5.25,;-5.78,-7.93,;-5.01,-9.27,;-3.46,-9.28,;-7.32,-7.93,;-8.1,-9.26,;-7.33,-10.6,;-9.64,-9.26,;-10.42,-10.59,;-2.05,-4.33,;-3.36,-3.53,;-.7,-3.61,;-.65,-2.07,;-1.95,-1.25,;-1.9,.29,;-.55,1,;-.5,2.54,;-1.8,3.34,;-3.16,2.62,;-3.2,1.1,;.7,-1.34,;2.01,-2.16,;.76,.2,;2.13,.92,;3.44,.09,;4.79,.81,;6.09,0,;4.84,2.35,;2.19,2.46,;.88,3.28,;3.54,3.17,;3.73,4.7,;2.51,5.63,;2.71,7.16,;5.16,5.31,;6.37,4.38,;5.42,6.81,;4.37,8.12,;5.25,9.52,;6.87,9.09,;6.73,7.58,;8,6.74,;7.92,5.2,;9.39,7.43,;10.67,6.6,;10.58,5.07,;11.89,4.21,;11.81,2.69,;10.44,2.02,;13.11,1.84,;12.06,7.29,;12.15,8.84,;13.36,6.46,;14.73,7.15,;14.82,8.68,;16.18,9.39,;16.41,10.9,;17.92,11.15,;18.63,9.81,;17.56,8.71,;16.02,6.31,;15.92,4.79,;17.39,7.01,;18.68,6.18,;18.59,4.65,;17.23,3.97,;17.14,2.41,;18.44,1.57,;15.78,1.72,;20.05,6.88,;20.15,8.44,;21.34,6.05,;22.73,6.75,;22.81,8.3,;21.52,9.14,;21.59,10.67,;20.3,11.53,;20.38,13.04,;21.74,13.73,;19.09,13.92,;24,5.91,;23.92,4.39,;25.39,6.61,;26.67,5.77,;28.05,6.48,;28.15,8.03,;29.33,5.65,;26.59,4.25,;25.21,3.57,;27.88,3.41,;27.8,1.87,;26.43,1.17,;25.15,2.01,;23.76,1.31,;23.68,-.24,;22.48,2.14,;29.09,1.01,;30.48,1.72,;29.05,-.53,;30.31,-1.41,;31.69,-.72,;32.97,-1.55,;34.37,-.84,;34.45,.71,;35.63,-1.69,;30.23,-2.94,;28.87,-3.62,;31.53,-3.79,;31.45,-5.31,;32.75,-6.16,;34.12,-5.46,;35.4,-6.3,;36.8,-5.6,;38.07,-6.42,;37.98,-7.95,;39.46,-5.73,;30.08,-6.01,;28.81,-5.16,;29.99,-7.55,;28.63,-8.24,;27.35,-7.41,;27.44,-5.88,;26.15,-5.04,;26.23,-3.51,;24.93,-2.66,;28.55,-9.79,;29.84,-10.64,;27.19,-10.49,;27.1,-12.03,;28.4,-12.89,;29.78,-12.18,;31.06,-13.03,;31,-14.51,;32.45,-12.32,;25.74,-12.73,;24.46,-11.89,;25.64,-14.28,;24.28,-14.96,;23.01,-14.13,;21.65,-14.8,;24.2,-16.51,;25.5,-17.36,;22.84,-17.21,;22.76,-18.76,;24.05,-19.61,;25.45,-18.91,;26.71,-19.73,;28.11,-19.04,;29.39,-19.87,;21.39,-19.44,;20.11,-18.61,;21.3,-21,;22.6,-21.84,;23.99,-21.15,;25.27,-21.98,;25.19,-23.51,;26.49,-24.35,;26.41,-25.88,;22.51,-23.37,;23.83,-24.21,;21.15,-24.06,;19.62,-23.43,;18.52,-24.69,;19.39,-26.14,;20.82,-25.53,;22,-26.54,;23.42,-25.93,;21.8,-28.06,;20.4,-28.97,;20.82,-30.6,;22.51,-30.69,;22.81,-29.17,;24.3,-28.76,;24.68,-27.26,;25.4,-29.83,;26.88,-29.42,;27.27,-27.94,;27.98,-30.51,;27.59,-31.99,;29.46,-30.1,;30.56,-31.18,;30.18,-32.67,;31.27,-33.75,;30.88,-35.24,;31.99,-36.32,;31.59,-37.81,;32.05,-30.77,;32.43,-29.27,;33.16,-31.83,;34.65,-31.44,;35.05,-29.96,;36.52,-29.55,;36.92,-28.06,;37.63,-30.63,;35.75,-32.53,;35.37,-34.01,;37.24,-32.12,;38.33,-33.2,;37.95,-34.7,;36.46,-35.1,;36.08,-36.6,;34.59,-37.01,;37.17,-37.67,;39.82,-32.79,;40.2,-31.31,;40.92,-33.88,;40.8,-35.55,;42.34,-36.19,;43.43,-34.92,;42.41,-33.74,;42.98,-32.31,;42.03,-31.11,;44.51,-32.1,;45.09,-30.67,;46.61,-30.46,;47.56,-31.66,;49.09,-31.45,;50.04,-32.65,;51.57,-32.44,;52.14,-31.01,;52.52,-33.66,;44.14,-29.46,;42.61,-29.65,;44.71,-28.04,)| Show InChI InChI=1S/C149H250N48O41/c1-9-10-11-12-16-45-115(205)169-75-103(190-136(227)104(76-198)172-116(206)73-154)135(226)188-101(71-84-32-14-13-15-33-84)133(224)187-100(70-81(4)5)132(223)192-106(78-200)144(235)195-66-29-42-108(195)139(230)181-95(51-57-118(209)210)128(219)189-102(72-85-74-165-79-170-85)134(225)180-92(47-53-112(156)202)126(217)176-90(39-26-63-167-148(161)162)130(221)193-119(82(6)7)141(232)182-93(48-54-113(157)203)127(218)178-91(46-52-111(155)201)125(216)175-89(38-25-62-166-147(159)160)122(213)174-87(35-18-22-59-151)121(212)179-94(50-56-117(207)208)129(220)191-105(77-199)137(228)177-88(36-19-23-60-152)123(214)183-96(37-20-24-61-153)142(233)197-68-31-44-110(197)145(236)196-67-30-41-107(196)138(229)171-83(8)120(211)173-86(34-17-21-58-150)124(215)186-99(69-80(2)3)131(222)184-97(49-55-114(158)204)143(234)194-65-28-43-109(194)140(231)185-98(146(237)238)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,198-200H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,201)(H2,156,202)(H2,157,203)(H2,158,204)(H,165,170)(H,169,205)(H,171,229)(H,172,206)(H,173,211)(H,174,213)(H,175,216)(H,176,217)(H,177,228)(H,178,218)(H,179,212)(H,180,225)(H,181,230)(H,182,232)(H,183,214)(H,184,222)(H,185,231)(H,186,215)(H,187,224)(H,188,226)(H,189,219)(H,190,227)(H,191,220)(H,192,223)(H,193,221)(H,207,208)(H,209,210)(H,237,238)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094056
(CHEMBL412799 | GSS(heptyl carbonyl)FLSPEHQRVQQRKES...)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O Show InChI InChI=1S/C96H157N31O30/c1-6-7-8-9-13-25-76(139)157-48-68(125-90(152)66(46-129)111-73(134)43-98)91(153)121-63(41-52-19-11-10-12-20-52)88(150)120-62(40-50(2)3)87(149)124-67(47-130)94(156)127-39-18-24-69(127)92(154)118-61(30-35-75(137)138)84(146)122-64(42-53-44-107-49-110-53)89(151)117-58(27-32-71(100)132)82(144)114-56(23-17-38-109-96(105)106)86(148)126-77(51(4)5)93(155)119-59(28-33-72(101)133)83(145)115-57(26-31-70(99)131)81(143)113-55(22-16-37-108-95(103)104)80(142)112-54(21-14-15-36-97)79(141)116-60(29-34-74(135)136)85(147)123-65(45-128)78(102)140/h10-12,19-20,44,49-51,54-69,77,128-130H,6-9,13-18,21-43,45-48,97-98H2,1-5H3,(H2,99,131)(H2,100,132)(H2,101,133)(H2,102,140)(H,107,110)(H,111,134)(H,112,142)(H,113,143)(H,114,144)(H,115,145)(H,116,141)(H,117,151)(H,118,154)(H,119,155)(H,120,150)(H,121,153)(H,122,146)(H,123,147)(H,124,149)(H,125,152)(H,126,148)(H,135,136)(H,137,138)(H4,103,104,108)(H4,105,106,109)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69+,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267950
(CHEMBL526723)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:53.53,62.64,94.96,105.107,130.132,150.152,165.167,174.176,197.202,34.33,121.123,75.76,211.215,wD:45.45,66.67,85.87,141.143,159.161,186.190,193.198,202.206,219.223,231.237,235.240,19.19,23.25,112.114,(8.99,-19.3,;9.02,-17.76,;10.36,-17.01,;10.38,-15.47,;11.73,-14.72,;11.75,-13.18,;10.43,-12.39,;9.09,-13.14,;7.76,-12.35,;6.42,-13.1,;5.1,-12.31,;3.75,-13.06,;2.43,-12.27,;1.08,-13.02,;-.24,-12.23,;-1.58,-12.98,;-1.61,-14.52,;-2.9,-12.19,;-4.25,-12.94,;-5.57,-12.15,;-6.91,-12.9,;-8.45,-12.92,;-9.24,-11.58,;-9.22,-14.26,;-8.43,-15.59,;-6.88,-15.58,;-10.76,-14.28,;-11.52,-15.62,;-10.73,-16.95,;-13.06,-15.64,;-13.82,-16.98,;-5.54,-10.61,;-6.86,-9.82,;-4.2,-9.87,;-4.17,-8.33,;-5.49,-7.52,;-5.46,-5.98,;-4.12,-5.25,;-4.09,-3.72,;-5.4,-2.93,;-6.75,-3.67,;-6.77,-5.2,;-2.83,-7.58,;-1.51,-8.38,;-2.79,-6.04,;-1.43,-5.3,;-.12,-6.1,;1.23,-5.37,;2.54,-6.16,;1.26,-3.83,;-1.4,-3.76,;-2.72,-2.96,;-.05,-3.03,;-.02,-1.49,;-1.33,-.68,;-1.29,.83,;1.33,-.73,;2.64,-1.53,;1.44,.79,;.26,1.98,;.99,3.48,;2.65,3.23,;2.67,1.68,;4.01,.99,;4.09,-.55,;5.32,1.81,;6.68,1.12,;6.75,-.42,;8.15,-1.13,;8.22,-2.65,;6.92,-3.46,;9.6,-3.37,;8,1.94,;7.93,3.51,;9.36,1.23,;10.65,2.08,;10.57,3.63,;11.85,4.45,;11.93,5.99,;13.41,6.39,;14.25,5.12,;13.29,3.91,;12.01,1.37,;12.07,-.14,;13.31,2.22,;14.67,1.52,;14.74,-.01,;13.45,-.83,;13.53,-2.39,;14.91,-3.09,;12.24,-3.21,;15.97,2.35,;15.9,3.92,;17.33,1.66,;18.64,2.5,;18.56,4.05,;17.19,4.75,;17.11,6.28,;15.73,6.99,;15.66,8.52,;16.94,9.34,;14.28,9.25,;19.99,1.8,;20.06,.28,;21.3,2.64,;22.66,1.93,;23.97,2.78,;23.9,4.32,;25.32,2.08,;22.74,.42,;21.44,-.4,;24.11,-.29,;24.18,-1.83,;22.9,-2.67,;21.54,-1.96,;20.23,-2.8,;20.3,-4.35,;18.86,-2.11,;25.56,-2.55,;26.87,-1.7,;25.67,-4.09,;27.03,-4.81,;28.33,-3.98,;29.69,-4.68,;31,-3.83,;30.93,-2.28,;32.35,-4.54,;27.11,-6.34,;25.83,-7.16,;28.49,-7.06,;28.56,-8.57,;29.94,-9.29,;31.24,-8.45,;32.6,-9.15,;33.91,-8.31,;35.26,-9,;35.34,-10.53,;36.57,-8.17,;27.27,-9.41,;25.92,-8.7,;27.34,-10.96,;26.06,-11.78,;24.7,-11.08,;24.64,-9.55,;23.26,-8.85,;23.18,-7.32,;21.81,-6.61,;26.14,-13.33,;27.51,-14.04,;24.85,-14.16,;24.93,-15.71,;26.31,-16.43,;27.61,-15.58,;28.97,-16.29,;29.06,-17.8,;30.28,-15.44,;23.65,-16.55,;22.29,-15.84,;23.71,-18.09,;22.43,-18.91,;21.07,-18.22,;19.78,-19.05,;22.51,-20.46,;23.88,-21.18,;21.22,-21.3,;21.3,-22.84,;22.68,-23.56,;23.99,-22.72,;25.34,-23.41,;26.65,-22.58,;28.01,-23.27,;20.01,-23.66,;18.66,-22.97,;20.08,-25.23,;21.46,-25.93,;22.77,-25.1,;24.13,-25.79,;24.21,-27.32,;25.58,-28.03,;25.66,-29.56,;21.53,-27.46,;22.92,-28.16,;20.25,-28.28,;18.66,-27.81,;17.7,-29.19,;18.7,-30.53,;20.07,-29.78,;21.34,-30.66,;22.69,-29.91,;21.31,-32.2,;20,-33.25,;20.59,-34.82,;22.28,-34.73,;22.42,-33.19,;23.87,-32.63,;24.09,-31.11,;25.07,-33.59,;26.5,-33.03,;26.73,-31.52,;27.71,-34,;27.47,-35.51,;29.13,-33.44,;30.33,-34.4,;30.11,-35.92,;31.31,-36.88,;31.08,-38.41,;32.28,-39.36,;32.04,-40.89,;31.78,-33.84,;32,-32.31,;32.99,-34.78,;34.43,-34.24,;34.68,-32.73,;36.1,-32.17,;36.34,-30.64,;37.31,-33.12,;35.64,-35.21,;35.41,-36.72,;37.08,-34.65,;38.28,-35.61,;38.05,-37.14,;36.61,-37.69,;36.38,-39.22,;34.94,-39.78,;37.58,-40.18,;39.72,-35.05,;39.94,-33.54,;40.92,-36.02,;40.97,-37.69,;42.57,-38.17,;43.53,-36.79,;42.39,-35.73,;42.81,-34.24,;41.74,-33.15,;44.31,-33.88,;44.74,-32.4,;46.23,-32.04,;47.3,-33.13,;48.8,-32.77,;49.87,-33.86,;51.36,-33.5,;51.79,-32.01,;52.43,-34.6,;43.67,-31.29,;42.17,-31.64,;44.09,-29.82,)| Show InChI InChI=1S/C157H265N47O42/c1-9-10-11-12-13-14-15-16-17-18-19-20-24-53-126(217)246-86-114(199-143(233)111(83-205)179-123(212)81-162)145(235)195-109(79-92-40-22-21-23-41-92)141(231)194-108(78-89(4)5)140(230)198-113(85-207)152(242)202-74-37-50-116(202)147(237)188-103(59-65-125(215)216)136(226)196-110(80-93-82-173-87-177-93)142(232)187-100(55-61-120(164)209)134(224)183-98(47-34-71-175-156(169)170)138(228)200-127(90(6)7)149(239)189-101(56-62-121(165)210)135(225)185-99(54-60-119(163)208)133(223)182-97(46-33-70-174-155(167)168)130(220)181-95(43-26-30-67-159)129(219)186-102(58-64-124(213)214)137(227)197-112(84-206)144(234)184-96(44-27-31-68-160)131(221)190-104(45-28-32-69-161)150(240)204-76-39-52-118(204)153(243)203-75-38-49-115(203)146(236)178-91(8)128(218)180-94(42-25-29-66-158)132(222)193-107(77-88(2)3)139(229)191-105(57-63-122(166)211)151(241)201-73-36-51-117(201)148(238)192-106(154(244)245)48-35-72-176-157(171)172/h21-23,40-41,82,87-91,94-118,127,205-207H,9-20,24-39,42-81,83-86,158-162H2,1-8H3,(H2,163,208)(H2,164,209)(H2,165,210)(H2,166,211)(H,173,177)(H,178,236)(H,179,212)(H,180,218)(H,181,220)(H,182,223)(H,183,224)(H,184,234)(H,185,225)(H,186,219)(H,187,232)(H,188,237)(H,189,239)(H,190,221)(H,191,229)(H,192,238)(H,193,222)(H,194,231)(H,195,235)(H,196,226)(H,197,227)(H,198,230)(H,199,233)(H,200,228)(H,213,214)(H,215,216)(H,244,245)(H4,167,168,174)(H4,169,170,175)(H4,171,172,176)/t91-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,127-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422315
(CHEMBL2310887)Show SMILES CCCC(CCC)C(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:178.182,223.229,185.190,97.99,11.11,151.153,58.59,37.37,166.168,113.115,133.135,211.215,194.198,227.232,wD:54.56,45.45,26.25,67.68,104.106,77.79,157.159,142.144,86.88,122.124,203.207,15.17,189.194,(43.59,-22.87,;42.1,-22.47,;41.7,-20.99,;40.21,-20.59,;39.12,-21.68,;39.52,-23.17,;38.43,-24.25,;39.81,-19.1,;38.33,-18.7,;40.9,-18.01,;40.5,-16.52,;41.59,-15.44,;43.08,-15.83,;43.48,-17.32,;42.39,-18.41,;44.97,-17.72,;46.06,-16.63,;45.66,-15.14,;45.37,-19.21,;46.85,-19.61,;47.94,-18.52,;47.25,-21.09,;48.74,-21.49,;41.2,-13.95,;42.28,-12.86,;39.71,-13.55,;39.31,-12.06,;40.4,-10.97,;40,-9.49,;38.51,-9.09,;38.11,-7.6,;39.2,-6.51,;40.69,-6.91,;41.09,-8.4,;37.82,-11.66,;36.73,-12.75,;37.42,-10.18,;35.94,-9.78,;34.85,-10.87,;33.36,-10.47,;32.27,-11.56,;32.96,-8.98,;35.54,-8.29,;36.63,-7.2,;34.05,-7.89,;33.65,-6.4,;34.74,-5.32,;34.34,-3.83,;32.16,-6.01,;31.07,-7.1,;31.76,-4.52,;32.73,-3.32,;31.89,-2.03,;30.41,-2.43,;30.33,-3.97,;29.03,-4.81,;29.12,-6.34,;27.66,-4.11,;26.37,-4.95,;26.45,-6.48,;25.16,-7.32,;25.24,-8.86,;26.61,-9.56,;23.95,-9.7,;25,-4.25,;25.84,-2.95,;23.71,-5.09,;22.34,-4.39,;22.25,-2.85,;23.55,-2.01,;23.63,-.47,;25.11,-.07,;25.95,-1.36,;24.98,-2.56,;21.04,-5.22,;21.12,-6.76,;19.67,-4.53,;19.59,-2.99,;20.88,-2.15,;20.8,-.61,;22.09,.23,;23.61,.47,;22.01,1.77,;18.22,-2.29,;18.14,-.75,;16.93,-3.13,;15.55,-2.43,;15.47,-.89,;14.1,-.19,;14.02,1.35,;12.65,2.05,;12.57,3.58,;11.2,4.28,;13.86,4.42,;14.26,-3.27,;14.34,-4.81,;12.89,-2.57,;11.6,-3.41,;11.68,-4.95,;10.39,-5.78,;13.05,-5.64,;10.23,-2.71,;10.15,-1.17,;8.94,-3.55,;7.56,-2.85,;7.48,-1.31,;6.11,-.61,;6.03,.93,;7.32,1.77,;4.66,1.63,;6.27,-3.69,;6.35,-5.22,;4.9,-2.99,;3.61,-3.83,;3.69,-5.36,;5.06,-6.06,;5.14,-7.6,;6.51,-8.3,;3.85,-8.44,;2.24,-3.13,;2.16,-1.59,;.94,-3.97,;-.43,-3.27,;-.51,-1.73,;-1.88,-1.03,;-1.96,.51,;-3.33,1.21,;-3.41,2.74,;-4.79,3.44,;-2.12,3.58,;-1.72,-4.11,;-1.64,-5.64,;-3.09,-3.41,;-4.38,-4.25,;-4.3,-5.78,;-2.93,-6.48,;-2.85,-8.02,;-1.48,-8.72,;-1.4,-10.26,;-5.75,-3.55,;-5.84,-2.01,;-7.05,-4.39,;-8.42,-3.69,;-8.5,-2.15,;-9.87,-1.45,;-9.95,.09,;-8.66,.93,;-11.32,.79,;-9.71,-4.53,;-9.63,-6.06,;-11.08,-3.83,;-12.37,-4.67,;-12.29,-6.2,;-13.58,-7.04,;-13.75,-3.97,;-13.83,-2.43,;-15.04,-4.81,;-16.41,-4.11,;-16.49,-2.57,;-17.86,-1.87,;-17.94,-.33,;-19.32,.37,;-19.4,1.91,;-17.7,-4.95,;-17.62,-6.48,;-19.07,-4.25,;-20.36,-5.09,;-20.28,-6.62,;-18.91,-7.32,;-18.83,-8.86,;-17.46,-9.56,;-17.38,-11.1,;-21.74,-4.39,;-21.82,-2.85,;-23.03,-5.22,;-23.11,-6.76,;-24.6,-7.16,;-25.44,-5.87,;-24.47,-4.67,;-24.86,-3.19,;-23.78,-2.1,;-26.35,-2.79,;-27.55,-3.76,;-28.84,-2.92,;-28.44,-1.43,;-26.9,-1.35,;-26.07,-.06,;-24.53,-.14,;-26.77,1.31,;-25.93,2.61,;-24.39,2.53,;-26.63,3.98,;-28.16,4.06,;-25.79,5.27,;-26.49,6.64,;-28.02,6.72,;-28.86,5.43,;-30.4,5.51,;-31.24,4.22,;-32.78,4.3,;-25.65,7.93,;-24.11,7.85,;-26.35,9.31,;-25.51,10.6,;-23.97,10.52,;-23.13,11.81,;-23.83,13.18,;-21.59,11.73,;-26.21,11.97,;-27.75,12.05,;-25.37,13.26,;-26.07,14.63,;-27.61,14.71,;-28.31,16.09,;-29.84,16.17,;-30.54,17.54,;-30.68,14.87,;-25.23,15.92,;-23.69,15.84,;-25.93,17.3,;-27.45,17.54,;-27.69,19.06,;-26.32,19.76,;-25.23,18.67,;-23.71,18.91,;-22.74,17.71,;-23.16,20.35,;-21.64,20.59,;-21.08,22.03,;-22.05,23.22,;-23.57,22.98,;-24.54,24.18,;-23.99,25.62,;-24.96,26.81,;-22.47,25.86,;-20.67,19.39,;-21.22,17.95,;-19.15,19.63,)| Show InChI InChI=1S/C149H249N47O42/c1-10-30-84(31-11-2)146(237)238-77-106(191-134(224)103(74-197)171-115(204)72-154)136(226)187-101(70-83-32-13-12-14-33-83)132(222)186-100(69-80(5)6)131(221)190-105(76-199)143(233)194-65-27-42-108(194)138(228)180-95(50-56-117(207)208)127(217)188-102(71-85-73-165-78-169-85)133(223)179-92(46-52-112(156)201)125(215)175-90(39-24-62-167-148(161)162)129(219)192-118(81(7)8)140(230)181-93(47-53-113(157)202)126(216)177-91(45-51-111(155)200)124(214)174-89(38-23-61-166-147(159)160)121(211)173-87(35-16-20-58-151)120(210)178-94(49-55-116(205)206)128(218)189-104(75-198)135(225)176-88(36-17-21-59-152)122(212)182-96(37-18-22-60-153)141(231)196-67-29-44-110(196)144(234)195-66-28-41-107(195)137(227)170-82(9)119(209)172-86(34-15-19-57-150)123(213)185-99(68-79(3)4)130(220)183-97(48-54-114(158)203)142(232)193-64-26-43-109(193)139(229)184-98(145(235)236)40-25-63-168-149(163)164/h12-14,32-33,73,78-82,84,86-110,118,197-199H,10-11,15-31,34-72,74-77,150-154H2,1-9H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,227)(H,171,204)(H,172,209)(H,173,211)(H,174,214)(H,175,215)(H,176,225)(H,177,216)(H,178,210)(H,179,223)(H,180,228)(H,181,230)(H,182,212)(H,183,220)(H,184,229)(H,185,213)(H,186,222)(H,187,226)(H,188,217)(H,189,218)(H,190,221)(H,191,224)(H,192,219)(H,205,206)(H,207,208)(H,235,236)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t82-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.960 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422311
(CHEMBL2310890)Show SMILES C\C=C\C=CC=CC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,w:5.4,3.2,wU:178.182,223.229,185.190,54.56,45.45,11.11,67.68,104.106,157.159,142.144,86.88,122.124,211.215,15.17,194.198,227.232,wD:97.99,151.153,26.25,58.59,37.37,166.168,77.79,113.115,133.135,203.207,189.194,(48.31,-12.34,;47.17,-11.31,;47.49,-9.8,;46.34,-8.77,;46.66,-7.27,;45.52,-6.24,;45.84,-4.73,;44.69,-3.7,;43.23,-4.18,;45.01,-2.19,;43.87,-1.16,;44.19,.34,;45.65,.82,;45.97,2.33,;44.83,3.36,;47.44,2.8,;48.58,1.77,;48.26,.26,;47.76,4.31,;49.22,4.78,;50.37,3.75,;49.54,6.29,;51.01,6.77,;43.04,1.37,;41.58,.9,;43.36,2.88,;42.22,3.91,;42.54,5.42,;41.4,6.45,;39.93,5.97,;38.79,7,;39.11,8.51,;40.57,8.98,;41.72,7.95,;40.76,3.43,;39.61,4.46,;40.44,1.93,;38.97,1.45,;37.83,2.48,;36.36,2.01,;36.04,.5,;35.22,3.04,;38.65,-.05,;39.8,-1.08,;37.19,-.53,;36.87,-2.04,;38.01,-3.07,;37.69,-4.57,;35.4,-2.51,;34.26,-1.48,;35.08,-4.02,;36.11,-5.16,;35.34,-6.5,;33.84,-6.18,;33.67,-4.65,;32.34,-3.88,;32.34,-2.34,;31.01,-4.65,;29.67,-3.88,;29.67,-2.34,;28.34,-1.57,;28.34,-.03,;29.67,.74,;27.01,.74,;28.34,-4.65,;28.34,-6.19,;27.01,-3.88,;25.67,-4.65,;25.67,-6.19,;24.34,-6.96,;22.93,-6.33,;21.9,-7.47,;22.67,-8.81,;24.18,-8.49,;24.34,-3.88,;24.34,-2.34,;23,-4.65,;21.67,-3.88,;21.67,-2.34,;23,-1.57,;23,-.03,;21.67,.74,;24.34,.74,;20.34,-4.65,;20.34,-6.19,;19,-3.88,;17.67,-4.65,;17.67,-6.19,;16.34,-6.96,;16.34,-8.5,;15,-9.27,;15,-10.81,;13.67,-11.58,;16.34,-11.58,;16.34,-3.88,;16.34,-2.34,;15,-4.65,;13.67,-3.88,;13.67,-2.34,;12.34,-1.57,;15,-1.57,;12.34,-4.65,;12.34,-6.19,;11,-3.88,;9.67,-4.65,;9.67,-6.19,;8.33,-6.96,;8.33,-8.5,;7,-9.27,;9.67,-9.27,;8.33,-3.88,;8.33,-2.34,;7,-4.65,;5.67,-3.88,;5.67,-2.34,;7,-1.57,;7,-.03,;5.67,.74,;8.33,.74,;4.33,-4.65,;4.33,-6.19,;3,-3.88,;1.67,-4.65,;1.67,-6.19,;.33,-6.96,;.33,-8.5,;1.67,-9.27,;1.67,-10.81,;3,-11.58,;.33,-11.58,;.33,-3.88,;.33,-2.34,;-1,-4.65,;-2.34,-3.88,;-2.34,-2.34,;-1,-1.57,;-1,-.03,;.33,.74,;.33,2.28,;-3.67,-4.65,;-3.67,-6.19,;-5,-3.88,;-6.34,-4.65,;-6.34,-6.19,;-7.67,-6.96,;-7.67,-8.5,;-9,-9.27,;-6.34,-9.27,;-7.67,-3.88,;-7.67,-2.34,;-9,-4.65,;-10.34,-3.88,;-10.34,-2.34,;-11.67,-1.57,;-11.67,-4.65,;-11.67,-6.19,;-13,-3.88,;-14.34,-4.65,;-14.34,-6.19,;-15.67,-6.96,;-15.67,-8.5,;-17.01,-9.27,;-17.01,-10.81,;-15.67,-3.88,;-15.67,-2.34,;-17.01,-4.65,;-18.34,-3.88,;-18.34,-2.34,;-17.01,-1.57,;-17.01,-.03,;-15.67,.74,;-15.67,2.28,;-19.67,-4.65,;-21.01,-3.88,;-19.67,-6.19,;-18.43,-7.09,;-18.9,-8.55,;-20.44,-8.55,;-20.92,-7.09,;-22.38,-6.61,;-22.7,-5.11,;-23.53,-7.64,;-23.37,-9.18,;-24.77,-9.8,;-25.8,-8.66,;-25.03,-7.32,;-25.66,-5.92,;-27.19,-5.76,;-24.76,-4.67,;-25.38,-3.26,;-24.48,-2.02,;-26.91,-3.1,;-27.82,-4.35,;-27.54,-1.7,;-29.07,-1.54,;-29.98,-2.78,;-29.35,-4.19,;-30.26,-5.43,;-29.63,-6.84,;-30.53,-8.09,;-29.7,-.13,;-28.79,1.12,;-31.23,.03,;-31.86,1.44,;-30.95,2.68,;-31.58,4.09,;-33.11,4.25,;-30.67,5.34,;-33.39,1.6,;-34.29,.35,;-34.01,3.01,;-35.55,3.17,;-36.45,1.92,;-37.98,2.08,;-38.89,.84,;-40.42,1,;-38.26,-.57,;-36.17,4.57,;-35.27,5.82,;-37.7,4.74,;-38.73,3.59,;-40.14,4.22,;-39.98,5.75,;-38.47,6.07,;-37.85,7.48,;-36.32,7.64,;-38.75,8.72,;-40.28,8.56,;-40.91,7.15,;-42.44,6.99,;-43.07,5.59,;-44.6,5.42,;-45.5,6.67,;-47.04,6.51,;-44.88,8.08,;-41.19,9.81,;-40.56,11.21,;-42.72,9.65,)| Show InChI InChI=1S/C149H243N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-135(225)103(75-197)171-115(204)73-154)137(227)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)190-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h9-16,32-33,45,74,79-83,86-110,119,197-199H,17-31,34-44,46-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/b10-9+,12-11?,45-16?/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094058
(CHEMBL263544 | GSS(heptyl carbonyl)FLSPEHQ-NH2)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(N)=O Show InChI InChI=1S/C55H84N14O17/c1-4-5-6-7-11-16-46(76)86-29-41(68-52(82)39(27-70)61-44(73)25-56)53(83)65-37(23-32-13-9-8-10-14-32)50(80)64-36(22-31(2)3)49(79)67-40(28-71)55(85)69-21-12-15-42(69)54(84)63-35(18-20-45(74)75)48(78)66-38(24-33-26-59-30-60-33)51(81)62-34(47(58)77)17-19-43(57)72/h8-10,13-14,26,30-31,34-42,70-71H,4-7,11-12,15-25,27-29,56H2,1-3H3,(H2,57,72)(H2,58,77)(H,59,60)(H,61,73)(H,62,81)(H,63,84)(H,64,80)(H,65,83)(H,66,78)(H,67,79)(H,68,82)(H,74,75)/t34-,35-,36-,37-,38-,39-,40-,41-,42+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094051
(CHEMBL412565 | GSS(heptyl carboxamide)FLSPEHQRVQQR...)Show SMILES CCCCCCCC(=O)NC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O Show InChI InChI=1S/C76H121N23O23/c1-6-7-8-9-13-20-59(105)85-36-52(96-71(117)53(37-100)87-60(106)34-77)70(116)94-50(32-42-16-11-10-12-17-42)68(114)93-49(31-40(2)3)67(113)97-54(38-101)74(120)99-30-15-19-55(99)72(118)90-47(24-28-61(107)108)65(111)95-51(33-43-35-83-39-86-43)69(115)89-45(21-25-56(78)102)63(109)88-44(18-14-29-84-76(81)82)66(112)98-62(41(4)5)73(119)91-46(22-26-57(79)103)64(110)92-48(75(121)122)23-27-58(80)104/h10-12,16-17,35,39-41,44-55,62,100-101H,6-9,13-15,18-34,36-38,77H2,1-5H3,(H2,78,102)(H2,79,103)(H2,80,104)(H,83,86)(H,85,105)(H,87,106)(H,88,109)(H,89,115)(H,90,118)(H,91,119)(H,92,110)(H,93,114)(H,94,116)(H,95,111)(H,96,117)(H,97,113)(H,98,112)(H,107,108)(H,121,122)(H4,81,82,84)/t44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55+,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094057
(CHEMBL410108 | GSS(heptyl carbonyl)FLSPEHQRVQQ)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O Show InChI InChI=1S/C76H120N22O24/c1-6-7-8-9-13-20-61(107)122-38-54(96-70(115)52(36-99)86-59(104)34-77)71(116)93-50(32-42-16-11-10-12-17-42)68(113)92-49(31-40(2)3)67(112)95-53(37-100)74(119)98-30-15-19-55(98)72(117)89-47(24-28-60(105)106)65(110)94-51(33-43-35-83-39-85-43)69(114)88-45(21-25-56(78)101)63(108)87-44(18-14-29-84-76(81)82)66(111)97-62(41(4)5)73(118)90-46(22-26-57(79)102)64(109)91-48(75(120)121)23-27-58(80)103/h10-12,16-17,35,39-41,44-55,62,99-100H,6-9,13-15,18-34,36-38,77H2,1-5H3,(H2,78,101)(H2,79,102)(H2,80,103)(H,83,85)(H,86,104)(H,87,108)(H,88,114)(H,89,117)(H,90,118)(H,91,109)(H,92,113)(H,93,116)(H,94,110)(H,95,112)(H,96,115)(H,97,111)(H,105,106)(H,120,121)(H4,81,82,84)/t44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55+,62-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422318
(CHEMBL2310894)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC(=O)c1ccccc1)NC(=O)[C@H](CO)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:29.29,222.229,22.21,107.109,182.198,54.58,141.149,163.171,36.43,89.96,69.76,210.215,8.13,226.232,wD:150.152,157.163,171.183,131.140,98.105,122.129,45.52,60.67,111.120,78.87,4.4,196.204,17.17,(-23.58,13.02,;-22.88,11.65,;-21.34,11.57,;-23.72,10.36,;-25.26,10.44,;-26.1,9.15,;-25.4,7.78,;-23.86,7.7,;-26.24,6.48,;-27.77,6.56,;-28.61,5.27,;-30.15,5.35,;-30.99,4.06,;-32.53,4.14,;-25.54,5.11,;-26.37,3.82,;-27.91,3.9,;-25.68,2.45,;-24.14,2.37,;-26.51,1.16,;-25.81,-.22,;-24.28,-.3,;-26.65,-1.51,;-28.19,-1.59,;-28.59,-3.08,;-27.3,-3.91,;-26.1,-2.94,;-24.61,-3.34,;-23.53,-2.25,;-24.22,-4.83,;-25.18,-6.03,;-24.35,-7.32,;-22.86,-6.92,;-22.78,-5.38,;-21.49,-4.54,;-21.57,-3.01,;-20.11,-5.24,;-20.03,-6.78,;-18.66,-7.48,;-18.58,-9.02,;-17.21,-9.72,;-17.13,-11.25,;-18.82,-4.4,;-17.45,-5.1,;-17.37,-6.64,;-16.16,-4.26,;-16.24,-2.73,;-17.61,-2.03,;-17.69,-.49,;-19.06,.21,;-19.15,1.75,;-14.79,-4.96,;-13.49,-4.12,;-13.58,-2.59,;-12.12,-4.82,;-12.04,-6.36,;-13.33,-7.2,;-10.83,-3.98,;-9.46,-4.68,;-9.38,-6.22,;-8.17,-3.84,;-8.25,-2.31,;-9.62,-1.61,;-9.7,-.07,;-8.41,.77,;-11.07,.63,;-6.8,-4.54,;-5.5,-3.7,;-5.58,-2.17,;-4.13,-4.4,;-4.05,-5.94,;-2.68,-6.64,;-2.6,-8.18,;-1.23,-8.88,;-1.15,-10.42,;-2.84,-3.56,;-1.47,-4.26,;-1.39,-5.8,;-.18,-3.43,;-.26,-1.89,;-1.63,-1.19,;-1.71,.35,;-3.08,1.05,;-3.16,2.59,;-4.54,3.29,;-1.87,3.43,;1.2,-4.12,;2.49,-3.29,;2.41,-1.75,;3.86,-3.98,;3.94,-5.52,;5.31,-6.22,;5.39,-7.76,;6.77,-8.46,;4.1,-8.6,;5.15,-3.15,;6.52,-3.84,;6.6,-5.38,;7.81,-3.01,;7.73,-1.47,;6.36,-.77,;6.28,.77,;4.91,1.47,;7.57,1.61,;9.19,-3.7,;10.48,-2.87,;10.4,-1.33,;11.85,-3.56,;13.14,-2.73,;14.51,-3.43,;14.59,-4.96,;15.81,-2.59,;15.72,-1.05,;14.35,-.35,;14.27,1.19,;12.9,1.89,;12.82,3.43,;11.45,4.12,;14.11,4.26,;17.18,-3.29,;18.47,-2.45,;18.39,-.91,;19.84,-3.15,;21.13,-2.31,;21.05,-.77,;22.34,.07,;22.26,1.61,;23.86,.31,;19.92,-4.68,;21.29,-5.38,;21.38,-6.92,;22.59,-4.54,;22.51,-3.01,;23.8,-2.17,;23.88,-.63,;25.36,-.23,;26.2,-1.52,;25.23,-2.72,;23.96,-5.24,;25.25,-4.4,;26.09,-3.11,;26.62,-5.1,;26.7,-6.64,;25.41,-7.48,;25.49,-9.02,;26.86,-9.72,;24.2,-9.86,;27.91,-4.26,;29.29,-4.96,;29.37,-6.5,;30.58,-4.12,;30.66,-2.59,;32.15,-2.19,;32.98,-3.48,;32.01,-4.68,;32.41,-6.16,;31.32,-7.25,;33.9,-6.56,;34.99,-5.47,;34.59,-3.99,;34.3,-8.05,;35.79,-8.45,;36.88,-7.36,;36.19,-9.94,;35.1,-11.02,;33.61,-10.63,;32.52,-11.71,;33.21,-9.14,;37.67,-10.33,;38.07,-11.82,;36.98,-12.91,;39.56,-12.22,;40.65,-11.13,;40.25,-9.64,;38.76,-9.24,;38.36,-7.76,;39.45,-6.67,;40.94,-7.07,;41.34,-8.55,;39.96,-13.71,;41.45,-14.11,;42.53,-13.02,;41.84,-15.59,;40.76,-16.68,;39.27,-16.28,;38.18,-17.37,;36.69,-16.97,;38.58,-18.86,;37.49,-19.95,;37.89,-21.44,;39.38,-21.84,;40.46,-20.75,;40.07,-19.26,;43.33,-15.99,;43.73,-17.48,;42.64,-18.57,;45.22,-17.88,;46.31,-16.79,;45.91,-15.3,;45.62,-19.37,;47.1,-19.76,;48.19,-18.67,;47.5,-21.25,;48.99,-21.65,;11.93,-5.1,;10.64,-5.94,;13.3,-5.8,;-25.96,11.81,;-27.49,11.89,;-25.12,13.1,;-25.82,14.48,;-27.36,14.56,;-28.05,15.93,;-29.59,16.01,;-30.29,17.38,;-30.43,14.72,;-24.98,15.77,;-23.44,15.69,;-25.68,17.14,;-27.2,17.38,;-27.44,18.9,;-26.07,19.6,;-24.98,18.51,;-23.46,18.75,;-22.49,17.56,;-22.91,20.19,;-21.38,20.43,;-20.83,21.87,;-21.8,23.07,;-23.32,22.82,;-24.29,24.02,;-23.74,25.46,;-24.71,26.66,;-22.22,25.7,;-20.42,19.23,;-20.97,17.8,;-18.89,19.48,)| Show InChI InChI=1S/C148H239N47O42/c1-78(2)67-98(129(219)182-96(47-53-113(157)202)141(231)192-63-25-42-108(192)138(228)183-97(144(234)235)39-24-62-167-148(162)163)184-122(212)85(33-14-18-56-149)171-118(208)81(7)169-136(226)106-40-27-65-194(106)143(233)109-43-28-66-195(109)140(230)95(36-17-21-59-152)181-121(211)87(35-16-20-58-151)175-134(224)103(74-197)188-127(217)93(48-54-115(204)205)177-119(209)86(34-15-19-57-150)172-120(210)88(37-22-60-165-146(158)159)173-123(213)90(44-50-110(154)199)176-125(215)92(46-52-112(156)201)180-139(229)117(80(5)6)191-128(218)89(38-23-61-166-147(160)161)174-124(214)91(45-51-111(155)200)178-132(222)101(70-84-72-164-77-168-84)187-126(216)94(49-55-116(206)207)179-137(227)107-41-26-64-193(107)142(232)104(75-198)189-130(220)99(68-79(3)4)185-131(221)100(69-82-29-10-8-11-30-82)186-135(225)105(76-237-145(236)83-31-12-9-13-32-83)190-133(223)102(73-196)170-114(203)71-153/h8-13,29-32,72,77-81,85-109,117,196-198H,14-28,33-71,73-76,149-153H2,1-7H3,(H2,154,199)(H2,155,200)(H2,156,201)(H2,157,202)(H,164,168)(H,169,226)(H,170,203)(H,171,208)(H,172,210)(H,173,213)(H,174,214)(H,175,224)(H,176,215)(H,177,209)(H,178,222)(H,179,227)(H,180,229)(H,181,211)(H,182,219)(H,183,228)(H,184,212)(H,185,221)(H,186,225)(H,187,216)(H,188,217)(H,189,220)(H,190,223)(H,191,218)(H,204,205)(H,206,207)(H,234,235)(H4,158,159,165)(H4,160,161,166)(H4,162,163,167)/t81-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083979
(CHEMBL540604 | N-(6-Amino-hexyl)-2-(4-oxo-2-phenet...)Show SMILES NCCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H34N4O2/c31-19-9-1-2-10-20-32-29(35)22-34-28(18-15-23-11-5-3-6-12-23)33-27-17-16-25(21-26(27)30(34)36)24-13-7-4-8-14-24/h3-8,11-14,16-17,21H,1-2,9-10,15,18-20,22,31H2,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083975
(CHEMBL536706 | N-(5-Amino-pentyl)-2-(4-oxo-2-phene...)Show SMILES NCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c30-18-8-3-9-19-31-28(34)21-33-27(17-14-22-10-4-1-5-11-22)32-26-16-15-24(20-25(26)29(33)35)23-12-6-2-7-13-23/h1-2,4-7,10-13,15-16,20H,3,8-9,14,17-19,21,30H2,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422310
(CHEMBL2310893)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)CN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:178.182,223.229,185.190,54.56,20.19,67.68,37.37,104.106,157.159,142.144,122.124,211.215,11.11,194.198,227.232,wD:97.99,45.45,151.153,26.25,58.59,166.168,77.79,113.115,133.135,86.88,203.207,189.194,(61.01,-15.33,;59.47,-15.44,;58.61,-14.16,;57.08,-14.27,;56.21,-13,;54.68,-13.11,;53.81,-11.83,;52.28,-11.94,;51.6,-13.33,;51.41,-10.67,;49.88,-10.78,;49.01,-9.5,;49.69,-8.12,;51.22,-8.01,;52.09,-9.28,;51.89,-6.62,;53.43,-6.51,;47.48,-9.61,;46.8,-11,;46.61,-8.34,;45.08,-8.45,;44.41,-9.83,;42.87,-9.94,;44.21,-7.17,;44.89,-5.79,;42.68,-7.28,;41.81,-6.01,;42.49,-4.62,;41.62,-3.35,;40.09,-3.46,;39.22,-2.18,;39.9,-.79,;41.43,-.68,;42.3,-1.96,;40.28,-6.12,;39.61,-7.5,;39.42,-4.84,;37.88,-4.95,;37.21,-6.34,;35.67,-6.45,;35,-7.83,;34.81,-5.17,;37.02,-3.68,;37.69,-2.29,;35.48,-3.79,;34.62,-2.51,;35.29,-1.13,;34.43,.15,;33.08,-2.62,;32.22,-1.35,;32.41,-4.01,;33.13,-5.36,;32.07,-6.47,;30.68,-5.8,;30.89,-4.28,;29.78,-3.21,;30.15,-1.71,;28.3,-3.64,;27.19,-2.57,;27.56,-1.07,;26.45,-.01,;26.82,1.49,;25.71,2.56,;28.3,1.92,;25.71,-2.99,;25.34,-4.49,;24.6,-1.93,;23.12,-2.35,;22.75,-3.85,;21.27,-4.28,;20.06,-3.33,;18.78,-4.19,;19.21,-5.67,;20.75,-5.72,;22.01,-1.29,;22.38,.21,;20.53,-1.71,;19.42,-.65,;19.79,.85,;21.27,1.28,;21.64,2.77,;20.53,3.84,;23.12,3.2,;17.95,-1.07,;17.58,-2.57,;16.84,-.01,;15.36,-.43,;14.25,.64,;14.62,2.13,;13.51,3.2,;13.88,4.69,;12.77,5.76,;13.14,7.26,;11.29,5.33,;14.99,-1.93,;16.1,-2.99,;13.51,-2.35,;12.4,-1.29,;12.77,.21,;11.66,1.28,;13.71,1.42,;10.92,-1.71,;10.55,-3.21,;9.81,-.65,;8.33,-1.07,;7.96,-2.57,;6.48,-2.99,;6.11,-4.49,;7.22,-5.56,;4.63,-4.92,;7.22,-.01,;7.59,1.49,;5.74,-.43,;4.63,.64,;5,2.13,;6.48,2.56,;6.85,4.05,;5.74,5.12,;8.33,4.48,;3.15,.21,;2.04,1.28,;2.78,-1.29,;1.3,-1.71,;.93,-3.21,;-.55,-3.64,;-.92,-5.13,;.19,-6.2,;-.18,-7.69,;.93,-8.76,;-1.66,-8.12,;.19,-.65,;.56,.85,;-1.29,-1.07,;-2.4,-.01,;-2.03,1.49,;-.55,1.92,;-.18,3.41,;1.3,3.84,;1.67,5.33,;-3.88,-.43,;-4.25,-1.93,;-4.99,.64,;-6.47,.21,;-6.84,-1.29,;-8.32,-1.71,;-8.69,-3.21,;-7.58,-4.28,;-10.17,-3.64,;-7.58,1.28,;-7.21,2.77,;-9.06,.85,;-10.17,1.92,;-9.8,3.41,;-10.91,4.48,;-11.65,1.49,;-12.02,-.01,;-12.76,2.56,;-14.24,2.13,;-14.61,.64,;-16.09,.21,;-16.46,-1.29,;-17.4,-2.5,;-16.82,-3.93,;-15.35,3.2,;-14.98,4.69,;-16.83,2.77,;-17.91,1.55,;-19.5,1.12,;-19.78,1.92,;-21.26,1.49,;-22.37,2.56,;-23.85,2.13,;-17.87,-.11,;-19.4,-.22,;-17,-1.38,;-15.47,-1.44,;-15.04,-2.91,;-16.31,-3.78,;-17.67,-3,;-19.01,-3.26,;-20.02,-2.1,;-19.51,-4.72,;-18.62,-5.98,;-19.55,-7.21,;-21,-6.71,;-20.98,-5.17,;-22.21,-4.24,;-23.63,-4.85,;-22.03,-2.72,;-23.26,-1.79,;-23.07,-.26,;-24.67,-2.4,;-24.86,-3.92,;-25.91,-1.47,;-27.32,-2.08,;-27.51,-3.6,;-26.27,-4.53,;-26.46,-6.06,;-25.23,-6.98,;-25.41,-8.51,;-28.55,-1.15,;-28.37,.38,;-29.97,-1.76,;-31.2,-.83,;-31.02,.7,;-32.25,1.62,;-33.66,1.02,;-32.06,3.15,;-32.62,-1.44,;-32.8,-2.96,;-33.85,-.51,;-35.27,-1.12,;-35.45,-2.64,;-36.87,-3.25,;-37.05,-4.78,;-38.47,-5.38,;-35.82,-5.7,;-36.5,-.19,;-36.31,1.34,;-37.91,-.8,;-38.26,-2.3,;-39.79,-2.43,;-40.4,-1.02,;-39.24,-0,;-39.37,1.53,;-38.11,2.41,;-40.77,2.18,;-40.91,3.71,;-42.3,4.36,;-42.44,5.89,;-43.84,6.54,;-43.97,8.08,;-42.71,8.96,;-42.85,10.49,;-41.32,8.31,;-39.65,4.6,;-38.25,3.95,;-39.78,6.13,)| Show InChI InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(171-115(204)73-154)137(227)190-104(76-198)136(226)187-101(71-84-32-14-13-15-33-84)133(223)186-100(70-81(4)5)132(222)191-105(77-199)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-103(75-197)135(225)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,225)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,226)(H,188,218)(H,189,219)(H,190,227)(H,191,222)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094055
(CHEMBL422461 | GSS(heptyl carbonyl)FL-NH2)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C31H50N6O8/c1-4-5-6-7-11-14-27(40)45-19-25(37-30(43)24(18-38)34-26(39)17-32)31(44)36-23(16-21-12-9-8-10-13-21)29(42)35-22(28(33)41)15-20(2)3/h8-10,12-13,20,22-25,38H,4-7,11,14-19,32H2,1-3H3,(H2,33,41)(H,34,39)(H,35,42)(H,36,44)(H,37,43)/t22-,23-,24-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083973
(CHEMBL539575 | N-(6-Amino-hexyl)-2-(6-bromo-4-oxo-...)Show SMILES NCCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(Br)cc2c1=O Show InChI InChI=1S/C24H29BrN4O2/c25-19-11-12-21-20(16-19)24(31)29(17-23(30)27-15-7-2-1-6-14-26)22(28-21)13-10-18-8-4-3-5-9-18/h3-5,8-9,11-12,16H,1-2,6-7,10,13-15,17,26H2,(H,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083978
(CHEMBL558181 | N-(6-Amino-hexyl)-2-(2-naphthalen-2...)Show SMILES NCCCCCCNC(=O)Cn1c(nc2ccc(cc2c1=O)-c1ccccc1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H32N4O2/c33-18-8-1-2-9-19-34-30(37)22-36-31(27-15-14-24-12-6-7-13-25(24)20-27)35-29-17-16-26(21-28(29)32(36)38)23-10-4-3-5-11-23/h3-7,10-17,20-21H,1-2,8-9,18-19,22,33H2,(H,34,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049478
(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 Show InChI InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083981
(CHEMBL538068 | N-(5-Amino-pentyl)-2-(2-naphthalen-...)Show SMILES NCCCCCNC(=O)Cn1c(nc2ccc(cc2c1=O)-c1ccccc1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H30N4O2/c32-17-7-2-8-18-33-29(36)21-35-30(26-14-13-23-11-5-6-12-24(23)19-26)34-28-16-15-25(20-27(28)31(35)37)22-9-3-1-4-10-22/h1,3-6,9-16,19-20H,2,7-8,17-18,21,32H2,(H,33,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083982
(CHEMBL540603 | N-(5-Amino-pentyl)-2-(6-bromo-4-oxo...)Show SMILES NCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(Br)cc2c1=O Show InChI InChI=1S/C23H27BrN4O2/c24-18-10-11-20-19(15-18)23(30)28(16-22(29)26-14-6-2-5-13-25)21(27-20)12-9-17-7-3-1-4-8-17/h1,3-4,7-8,10-11,15H,2,5-6,9,12-14,16,25H2,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094064
(CHEMBL335799 | GSS(heptyl carbonyl)F-NH2)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C25H39N5O7/c1-2-3-4-5-9-12-22(33)37-16-20(30-24(35)19(15-31)28-21(32)14-26)25(36)29-18(23(27)34)13-17-10-7-6-8-11-17/h6-8,10-11,18-20,31H,2-5,9,12-16,26H2,1H3,(H2,27,34)(H,28,32)(H,29,36)(H,30,35)/t18-,19-,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 889 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083976
(CHEMBL536779 | N-(6-Amino-hexyl)-2-(6-bromo-2-naph...)Show SMILES NCCCCCCNC(=O)Cn1c(nc2ccc(Br)cc2c1=O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C26H27BrN4O2/c27-21-11-12-23-22(16-21)26(33)31(17-24(32)29-14-6-2-1-5-13-28)25(30-23)20-10-9-18-7-3-4-8-19(18)15-20/h3-4,7-12,15-16H,1-2,5-6,13-14,17,28H2,(H,29,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422314
(CHEMBL2310892)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:178.182,185.190,223.229,97.99,34.37,151.153,58.59,15.19,166.168,113.115,133.135,211.215,194.198,227.232,wD:54.56,11.11,23.31,67.68,104.106,77.79,157.159,142.144,86.88,122.124,203.207,40.43,189.194,(47.19,-3.87,;45.71,-3.47,;44.62,-4.56,;43.13,-4.16,;42.04,-5.25,;40.55,-4.86,;39.46,-5.94,;37.98,-5.55,;37.58,-4.06,;36.89,-6.64,;35.4,-6.24,;34.31,-7.33,;34.71,-8.81,;36.2,-9.21,;37.29,-8.12,;36.6,-10.7,;35.51,-11.79,;34.02,-11.39,;32.93,-12.48,;33.62,-9.9,;38.08,-11.1,;38.48,-12.58,;37.39,-13.67,;39.97,-12.98,;41.06,-11.89,;40.66,-10.41,;39.17,-10.01,;38.77,-8.52,;39.86,-7.43,;41.35,-7.83,;41.75,-9.32,;40.37,-14.47,;41.86,-14.87,;42.95,-13.78,;42.26,-16.36,;41.17,-17.45,;39.68,-17.05,;43.74,-16.76,;44.14,-18.24,;43.05,-19.33,;45.63,-18.64,;46.72,-17.55,;46.32,-16.06,;46.03,-20.13,;47.52,-20.53,;48.6,-19.44,;47.91,-22.01,;49.4,-22.41,;32.82,-6.93,;31.74,-8.02,;32.43,-5.44,;33.39,-4.24,;32.56,-2.95,;31.07,-3.35,;30.99,-4.89,;29.7,-5.73,;29.78,-7.26,;28.32,-5.03,;27.03,-5.87,;27.11,-7.4,;25.82,-8.24,;25.9,-9.78,;27.27,-10.48,;24.61,-10.62,;25.66,-5.17,;26.5,-3.88,;24.37,-6.01,;23,-5.31,;22.92,-3.77,;24.21,-2.93,;24.29,-1.39,;25.78,-.99,;26.61,-2.29,;25.65,-3.48,;21.71,-6.15,;21.79,-7.68,;20.33,-5.45,;20.25,-3.91,;21.54,-3.07,;21.46,-1.53,;22.75,-.69,;24.28,-.45,;22.67,.84,;18.88,-3.21,;18.8,-1.67,;17.59,-4.05,;16.22,-3.35,;16.14,-1.81,;14.76,-1.11,;14.68,.42,;13.31,1.12,;13.23,2.66,;11.86,3.36,;14.52,3.5,;14.92,-4.19,;15.01,-5.73,;13.55,-3.49,;12.26,-4.33,;12.34,-5.87,;11.05,-6.71,;13.71,-6.57,;10.89,-3.63,;10.81,-2.09,;9.6,-4.47,;8.23,-3.77,;8.14,-2.23,;6.77,-1.53,;6.69,.01,;7.98,.84,;5.32,.7,;6.93,-4.61,;7.01,-6.15,;5.56,-3.91,;4.27,-4.75,;4.35,-6.29,;5.72,-6.98,;5.8,-8.52,;4.51,-9.36,;7.18,-9.22,;2.9,-4.05,;2.82,-2.51,;1.61,-4.89,;.23,-4.19,;.15,-2.65,;-1.22,-1.95,;-1.3,-.41,;-2.67,.29,;-2.75,1.82,;-4.12,2.52,;-1.46,2.66,;-1.06,-5.03,;-.98,-6.57,;-2.43,-4.33,;-3.72,-5.17,;-3.64,-6.71,;-2.27,-7.4,;-2.19,-8.94,;-.81,-9.64,;-.73,-11.18,;-5.09,-4.47,;-5.17,-2.93,;-6.38,-5.31,;-7.76,-4.61,;-7.84,-3.07,;-9.21,-2.37,;-9.29,-.83,;-8,.01,;-10.66,-.13,;-9.05,-5.45,;-8.97,-6.98,;-10.42,-4.75,;-11.71,-5.59,;-11.63,-7.12,;-12.92,-7.96,;-13.08,-4.89,;-13.16,-3.35,;-14.38,-5.73,;-15.75,-5.03,;-15.83,-3.49,;-17.2,-2.79,;-17.28,-1.25,;-18.65,-.55,;-18.73,.98,;-17.04,-5.87,;-16.96,-7.4,;-18.41,-5.17,;-19.7,-6.01,;-19.62,-7.54,;-18.25,-8.24,;-18.17,-9.78,;-16.8,-10.48,;-16.72,-12.02,;-21.08,-5.31,;-21.16,-3.77,;-22.37,-6.15,;-22.45,-7.68,;-23.93,-8.08,;-24.77,-6.79,;-23.8,-5.59,;-24.2,-4.11,;-23.11,-3.02,;-25.69,-3.71,;-26.89,-4.68,;-28.18,-3.84,;-27.78,-2.35,;-26.24,-2.27,;-25.4,-.98,;-23.87,-1.06,;-26.1,.39,;-25.26,1.68,;-23.73,1.6,;-25.96,3.06,;-27.5,3.14,;-25.13,4.35,;-25.82,5.72,;-27.36,5.8,;-28.2,4.51,;-29.74,4.59,;-30.58,3.3,;-32.12,3.38,;-24.99,7.01,;-23.45,6.93,;-25.69,8.38,;-24.85,9.68,;-23.31,9.6,;-22.47,10.89,;-23.17,12.26,;-20.93,10.81,;-25.55,11.05,;-27.08,11.13,;-24.71,12.34,;-25.41,13.71,;-26.94,13.79,;-27.64,15.16,;-29.18,15.24,;-29.88,16.62,;-30.02,13.95,;-24.57,15,;-23.03,14.92,;-25.27,16.38,;-26.79,16.62,;-27.03,18.14,;-25.66,18.84,;-24.57,17.75,;-23.05,17.99,;-22.08,16.79,;-22.5,19.43,;-20.97,19.67,;-20.42,21.11,;-21.39,22.3,;-22.91,22.06,;-23.88,23.26,;-23.33,24.7,;-24.3,25.89,;-21.81,24.94,;-20,18.47,;-20.56,17.03,;-18.48,18.71,)| Show InChI InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(191-132(222)100(70-81(4)5)186-133(223)101(71-84-32-14-13-15-33-84)187-137(227)105(77-199)190-135(225)103(75-197)171-115(204)73-154)144(234)194-66-29-42-108(194)139(229)180-95(51-57-117(207)208)128(218)188-102(72-85-74-165-79-169-85)134(224)179-92(47-53-112(156)201)126(216)175-90(39-26-63-167-148(161)162)130(220)192-119(82(6)7)141(231)181-93(48-54-113(157)202)127(217)177-91(46-52-111(155)200)125(215)174-89(38-25-62-166-147(159)160)122(212)173-87(35-18-22-59-151)121(211)178-94(50-56-116(205)206)129(219)189-104(76-198)136(226)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,225)(H,191,222)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422312
(CHEMBL2310886)Show SMILES CCCNC(=O)CCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:55.57,46.46,12.12,27.26,68.69,105.107,158.160,143.145,87.89,123.125,204.208,16.18,190.195,wD:179.183,224.230,186.191,98.100,152.154,59.60,38.38,167.169,78.80,114.116,134.136,212.216,195.199,228.233,(50.89,21.84,;50.57,20.33,;49.11,19.86,;48.79,18.35,;47.32,17.88,;46.18,18.91,;47,16.37,;45.54,15.89,;45.22,14.39,;46.36,13.36,;43.75,13.91,;43.43,12.41,;41.97,11.93,;40.83,12.96,;39.36,12.48,;39.04,10.98,;38.22,13.51,;38.54,15.02,;40,15.5,;36.75,13.04,;35.61,14.07,;35.93,15.58,;34.14,13.59,;33,14.62,;41.65,10.42,;42.79,9.39,;40.19,9.95,;39.87,8.44,;41.01,7.41,;40.69,5.9,;41.83,4.87,;41.51,3.37,;40.05,2.89,;38.9,3.92,;39.22,5.43,;38.4,7.97,;37.26,9,;38.08,6.46,;36.62,5.98,;35.47,7.01,;34.01,6.54,;33.69,5.03,;32.86,7.57,;36.3,4.48,;37.44,3.45,;34.83,4,;34.51,2.49,;35.66,1.46,;35.33,-.04,;33.05,2.02,;31.9,3.05,;32.73,.51,;33.76,-.63,;32.99,-1.97,;31.48,-1.65,;31.32,-.11,;29.99,.66,;29.99,2.2,;28.65,-.11,;27.32,.66,;27.32,2.2,;25.98,2.97,;25.98,4.51,;24.65,5.28,;27.32,5.28,;25.98,-.11,;25.98,-1.65,;24.65,.66,;23.32,-.11,;23.32,-1.65,;21.98,-2.42,;21.82,-3.96,;20.32,-4.28,;19.55,-2.94,;20.58,-1.8,;21.98,.66,;21.98,2.2,;20.65,-.11,;19.32,.66,;19.32,2.2,;20.65,2.97,;20.65,4.51,;19.32,5.28,;21.98,5.28,;17.98,-.11,;17.98,-1.65,;16.65,.66,;15.31,-.11,;15.31,-1.65,;13.98,-2.42,;13.98,-3.96,;12.65,-4.73,;12.65,-6.27,;11.31,-7.04,;13.98,-7.04,;13.98,.66,;13.98,2.2,;12.65,-.11,;11.31,.66,;11.31,2.2,;9.98,2.97,;12.65,2.97,;9.98,-.11,;9.98,-1.65,;8.65,.66,;7.31,-.11,;7.31,-1.65,;5.98,-2.42,;5.98,-3.96,;7.31,-4.73,;4.65,-4.73,;5.98,.66,;5.98,2.2,;4.65,-.11,;3.31,.66,;3.31,2.2,;4.65,2.97,;4.65,4.51,;3.31,5.28,;5.98,5.28,;1.98,-.11,;1.98,-1.65,;.64,.66,;-.69,-.11,;-.69,-1.65,;-2.02,-2.42,;-2.02,-3.96,;-3.36,-4.73,;-3.36,-6.27,;-4.69,-7.04,;-2.02,-7.04,;-2.02,.66,;-2.02,2.2,;-3.36,-.11,;-4.69,.66,;-4.69,2.2,;-3.36,2.97,;-3.36,4.51,;-2.02,5.28,;-2.02,6.82,;-6.02,-.11,;-6.02,-1.65,;-7.36,.66,;-8.69,-.11,;-8.69,-1.65,;-10.03,-2.42,;-10.03,-3.96,;-8.69,-4.73,;-11.36,-4.73,;-10.03,.66,;-10.03,2.2,;-11.36,-.11,;-12.69,.66,;-12.69,2.2,;-14.03,2.97,;-14.03,-.11,;-14.03,-1.65,;-15.36,.66,;-16.69,-.11,;-16.69,-1.65,;-18.03,-2.42,;-18.03,-3.96,;-19.36,-4.73,;-19.36,-6.27,;-18.03,.66,;-18.03,2.2,;-19.36,-.11,;-20.69,.66,;-20.69,2.2,;-19.36,2.97,;-19.36,4.51,;-18.03,5.28,;-18.03,6.82,;-22.03,-.11,;-22.03,-1.65,;-23.36,.66,;-23.52,2.19,;-25.03,2.51,;-25.8,1.17,;-24.77,.03,;-25.09,-1.48,;-23.94,-2.51,;-26.55,-1.95,;-27.8,-1.05,;-29.05,-1.95,;-28.57,-3.42,;-27.03,-3.42,;-26.12,-4.66,;-24.59,-4.5,;-26.75,-6.07,;-25.85,-7.32,;-24.31,-7.16,;-26.47,-8.72,;-28,-8.88,;-25.57,-9.97,;-26.19,-11.38,;-27.72,-11.54,;-28.63,-10.29,;-30.16,-10.45,;-31.07,-9.21,;-32.6,-9.37,;-25.29,-12.62,;-23.76,-12.46,;-25.91,-14.03,;-25.01,-15.27,;-23.48,-15.11,;-22.57,-16.36,;-23.2,-17.77,;-21.04,-16.2,;-25.64,-16.68,;-27.17,-16.84,;-24.73,-17.93,;-25.36,-19.33,;-26.89,-19.5,;-27.51,-20.9,;-29.05,-21.06,;-29.67,-22.47,;-29.95,-19.82,;-24.45,-20.58,;-22.92,-20.42,;-25.08,-21.99,;-26.58,-22.31,;-26.75,-23.84,;-25.34,-24.47,;-24.31,-23.32,;-22.78,-23.48,;-21.87,-22.24,;-22.15,-24.89,;-23.06,-26.13,;-24.59,-25.97,;-25.49,-27.22,;-27.02,-27.06,;-27.93,-28.3,;-27.3,-29.71,;-28.21,-30.96,;-25.77,-29.87,;-22.43,-27.54,;-20.9,-27.7,;-23.33,-28.79,)| Show InChI InChI=1S/C148H246N48O43/c1-9-59-165-113(204)51-54-117(210)239-76-104(191-134(226)101(73-197)171-114(205)71-153)136(228)187-99(69-82-28-11-10-12-29-82)132(224)186-98(68-79(4)5)131(223)190-103(75-199)143(235)194-64-25-38-106(194)138(230)180-93(46-53-116(208)209)127(219)188-100(70-83-72-164-77-169-83)133(225)179-90(42-48-110(155)201)125(217)175-88(35-22-61-167-147(160)161)129(221)192-118(80(6)7)140(232)181-91(43-49-111(156)202)126(218)177-89(41-47-109(154)200)124(216)174-87(34-21-60-166-146(158)159)121(213)173-85(31-14-18-56-150)120(212)178-92(45-52-115(206)207)128(220)189-102(74-198)135(227)176-86(32-15-19-57-151)122(214)182-94(33-16-20-58-152)141(233)196-66-27-40-108(196)144(236)195-65-26-37-105(195)137(229)170-81(8)119(211)172-84(30-13-17-55-149)123(215)185-97(67-78(2)3)130(222)183-95(44-50-112(157)203)142(234)193-63-24-39-107(193)139(231)184-96(145(237)238)36-23-62-168-148(162)163/h10-12,28-29,72,77-81,84-108,118,197-199H,9,13-27,30-71,73-76,149-153H2,1-8H3,(H2,154,200)(H2,155,201)(H2,156,202)(H2,157,203)(H,164,169)(H,165,204)(H,170,229)(H,171,205)(H,172,211)(H,173,213)(H,174,216)(H,175,217)(H,176,227)(H,177,218)(H,178,212)(H,179,225)(H,180,230)(H,181,232)(H,182,214)(H,183,222)(H,184,231)(H,185,215)(H,186,224)(H,187,228)(H,188,219)(H,189,220)(H,190,223)(H,191,226)(H,192,221)(H,206,207)(H,208,209)(H,237,238)(H4,158,159,166)(H4,160,161,167)(H4,162,163,168)/t81-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,118-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083980
(CHEMBL535353 | N-(5-Amino-pentyl)-2-(6-bromo-2-nap...)Show SMILES NCCCCCNC(=O)Cn1c(nc2ccc(Br)cc2c1=O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C25H25BrN4O2/c26-20-10-11-22-21(15-20)25(32)30(16-23(31)28-13-5-1-4-12-27)24(29-22)19-9-8-17-6-2-3-7-18(17)14-19/h2-3,6-11,14-15H,1,4-5,12-13,16,27H2,(H,28,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267949
(CHEMBL504856)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC(C)=O)NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:8.16,39.39,48.50,80.82,91.93,116.118,136.138,151.153,160.162,183.188,107.109,61.62,197.201,wD:4.4,52.53,71.73,127.129,145.147,172.176,179.184,188.192,205.209,217.223,221.226,19.25,28.31,98.100,(7.5,-7.44,;6.19,-6.65,;6.22,-5.11,;4.85,-7.38,;3.53,-6.58,;2.17,-7.32,;2.13,-8.86,;3.45,-9.66,;.79,-9.61,;-.52,-8.8,;-.49,-7.26,;.84,-6.54,;.87,-5,;-.44,-4.21,;-1.79,-4.95,;-1.81,-6.48,;.76,-11.15,;-.58,-11.89,;-1.9,-11.1,;-.61,-13.43,;.71,-14.22,;2.06,-13.47,;3.38,-14.26,;4.72,-13.51,;3.36,-15.8,;-1.95,-14.18,;-3.48,-14.2,;-4.27,-12.86,;-4.25,-15.54,;-3.47,-16.87,;-1.91,-16.85,;-5.79,-15.56,;-6.55,-16.9,;-5.77,-18.23,;-8.09,-16.92,;-8.85,-18.26,;3.56,-5.04,;2.24,-4.24,;4.91,-4.31,;4.94,-2.77,;3.63,-1.97,;3.67,-.46,;6.29,-2.01,;7.6,-2.82,;6.4,-.49,;5.22,.69,;5.95,2.19,;7.6,1.94,;7.62,.4,;8.97,-.3,;9.05,-1.84,;10.28,.53,;11.64,-.17,;11.71,-1.7,;13.1,-2.42,;13.18,-3.93,;11.88,-4.75,;14.56,-4.65,;12.95,.66,;12.88,2.22,;14.32,-.05,;15.6,.8,;15.53,2.35,;16.81,3.17,;16.89,4.71,;18.37,5.11,;19.2,3.83,;18.25,2.62,;16.97,.09,;17.03,-1.42,;18.26,.93,;19.62,.24,;19.69,-1.29,;18.41,-2.11,;18.48,-3.67,;19.86,-4.37,;17.2,-4.49,;20.92,1.07,;20.86,2.63,;22.28,.38,;23.6,1.22,;23.52,2.77,;22.14,3.47,;22.06,5,;20.69,5.7,;20.61,7.23,;21.89,8.06,;19.23,7.96,;24.94,.51,;25.02,-1,;26.25,1.36,;27.61,.65,;28.92,1.49,;28.85,3.04,;30.27,.8,;27.69,-.86,;26.39,-1.69,;29.06,-1.58,;29.14,-3.11,;27.85,-3.95,;26.49,-3.24,;25.18,-4.09,;25.26,-5.63,;23.82,-3.39,;30.51,-3.83,;31.82,-2.99,;30.63,-5.37,;31.98,-6.09,;33.28,-5.26,;34.64,-5.96,;35.96,-5.11,;35.88,-3.56,;37.3,-5.82,;32.06,-7.62,;30.78,-8.44,;33.44,-8.34,;33.51,-9.85,;34.89,-10.57,;36.19,-9.72,;37.55,-10.43,;38.86,-9.59,;40.21,-10.28,;40.28,-11.81,;41.52,-9.45,;32.22,-10.69,;30.87,-9.98,;32.29,-12.24,;31.01,-13.06,;29.66,-12.36,;29.59,-10.83,;28.21,-10.13,;28.14,-8.6,;26.76,-7.88,;31.09,-14.6,;32.47,-15.32,;29.81,-15.44,;29.88,-16.99,;31.26,-17.7,;32.56,-16.86,;33.92,-17.57,;34.01,-19.08,;35.23,-16.72,;28.6,-17.82,;27.24,-17.11,;28.66,-19.37,;27.38,-20.19,;26.03,-19.5,;24.74,-20.32,;27.46,-21.74,;28.83,-22.45,;26.18,-22.57,;26.25,-24.12,;27.63,-24.84,;28.94,-23.99,;30.29,-24.68,;31.6,-23.85,;32.96,-24.55,;24.96,-24.94,;23.61,-24.25,;25.03,-26.5,;26.42,-27.2,;27.72,-26.37,;29.08,-27.07,;29.16,-28.6,;30.54,-29.3,;30.61,-30.83,;26.49,-28.73,;27.88,-29.43,;25.2,-29.55,;23.61,-29.09,;22.65,-30.46,;23.66,-31.8,;25.02,-31.05,;26.3,-31.93,;27.65,-31.18,;26.26,-33.47,;24.96,-34.52,;25.55,-36.09,;27.23,-36.01,;27.38,-34.46,;28.82,-33.9,;29.04,-32.38,;30.02,-34.86,;31.45,-34.3,;31.68,-32.79,;32.66,-35.27,;32.42,-36.78,;34.09,-34.71,;35.29,-35.67,;35.06,-37.19,;36.26,-38.15,;36.03,-39.68,;37.23,-40.63,;36.99,-42.16,;36.73,-35.11,;36.95,-33.58,;37.94,-36.05,;39.39,-35.51,;39.63,-34,;41.05,-33.44,;41.29,-31.91,;42.26,-34.39,;40.59,-36.48,;40.36,-37.99,;42.03,-35.92,;43.23,-36.88,;43,-38.4,;41.56,-38.96,;41.33,-40.49,;39.89,-41.05,;42.53,-41.45,;44.67,-36.32,;44.89,-34.81,;45.87,-37.29,;45.92,-38.96,;47.52,-39.44,;48.47,-38.06,;47.33,-37,;47.76,-35.51,;46.69,-34.42,;49.26,-35.15,;49.68,-33.67,;51.18,-33.31,;52.25,-34.4,;53.74,-34.04,;54.81,-35.13,;56.31,-34.77,;56.73,-33.28,;57.38,-35.87,;48.61,-32.56,;47.12,-32.91,;49.04,-31.09,)| Show InChI InChI=1S/C143H237N47O42/c1-74(2)63-94(125(215)177-92(43-49-109(152)198)137(227)187-59-23-38-104(187)134(224)178-93(140(230)231)35-22-58-162-143(157)158)179-118(208)81(29-12-16-52-144)166-114(204)77(7)164-132(222)102-36-25-61-189(102)139(229)105-39-26-62-190(105)136(226)91(32-15-19-55-147)176-117(207)83(31-14-18-54-146)170-130(220)99(70-192)183-123(213)89(44-50-111(200)201)172-115(205)82(30-13-17-53-145)167-116(206)84(33-20-56-160-141(153)154)168-119(209)86(40-46-106(149)195)171-121(211)88(42-48-108(151)197)175-135(225)113(76(5)6)186-124(214)85(34-21-57-161-142(155)156)169-120(210)87(41-47-107(150)196)173-128(218)97(66-80-68-159-73-163-80)182-122(212)90(45-51-112(202)203)174-133(223)103-37-24-60-188(103)138(228)100(71-193)184-126(216)95(64-75(3)4)180-127(217)96(65-79-27-10-9-11-28-79)181-131(221)101(72-232-78(8)194)185-129(219)98(69-191)165-110(199)67-148/h9-11,27-28,68,73-77,81-105,113,191-193H,12-26,29-67,69-72,144-148H2,1-8H3,(H2,149,195)(H2,150,196)(H2,151,197)(H2,152,198)(H,159,163)(H,164,222)(H,165,199)(H,166,204)(H,167,206)(H,168,209)(H,169,210)(H,170,220)(H,171,211)(H,172,205)(H,173,218)(H,174,223)(H,175,225)(H,176,207)(H,177,215)(H,178,224)(H,179,208)(H,180,217)(H,181,221)(H,182,212)(H,183,213)(H,184,216)(H,185,219)(H,186,214)(H,200,201)(H,202,203)(H,230,231)(H4,153,154,160)(H4,155,156,161)(H4,157,158,162)/t77-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,113-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50267263
(CHEMBL509512)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC(=O)CCCCCCN)NC(=O)[C@H](CO)NC(=O)CN)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:8.16,45.45,54.56,86.88,97.99,122.124,142.144,157.159,166.168,189.194,113.115,67.68,203.207,wD:4.4,58.59,77.79,133.135,151.153,178.182,185.190,194.198,211.215,223.229,227.232,19.31,34.37,104.106,(6.39,-6.67,;5.09,-5.86,;5.14,-4.32,;3.74,-6.58,;2.43,-5.75,;1.06,-6.47,;1,-8.01,;2.31,-8.83,;-.35,-8.74,;-1.65,-7.92,;-1.6,-6.38,;-.25,-5.67,;-.2,-4.13,;-1.5,-3.33,;-2.86,-4.05,;-2.9,-5.57,;-.4,-10.28,;-1.75,-11,;-3.06,-10.2,;-1.8,-12.54,;-.49,-13.35,;.86,-12.62,;2.17,-13.42,;2.13,-14.96,;3.9,-12.59,;5.49,-13.68,;7.22,-12.84,;8.81,-13.93,;10.54,-13.1,;12.13,-14.18,;13.87,-13.35,;-3.15,-13.27,;-4.69,-13.27,;-5.46,-11.92,;-5.48,-14.6,;-4.71,-15.94,;-3.16,-15.95,;-7.02,-14.59,;-7.8,-15.92,;-7.03,-17.26,;-9.34,-15.92,;-10.12,-17.25,;2.49,-4.21,;1.18,-3.39,;3.84,-3.5,;4.03,-1.97,;2.81,-1.04,;3.01,.48,;5.45,-1.36,;6.67,-2.29,;5.72,.14,;4.67,1.44,;5.55,2.85,;7.17,2.42,;7.03,.9,;8.3,.07,;8.22,-1.47,;9.68,.76,;10.96,-.07,;10.88,-1.61,;12.19,-2.46,;12.11,-3.98,;10.73,-4.65,;13.4,-4.83,;12.35,.61,;12.44,2.17,;13.65,-.21,;15.03,.48,;15.11,2.01,;16.47,2.71,;16.7,4.22,;18.21,4.46,;18.92,3.14,;17.85,2.03,;16.31,-.36,;16.21,-1.88,;17.68,.34,;18.97,-.49,;18.88,-2.02,;17.52,-2.7,;17.43,-4.26,;18.73,-5.1,;16.07,-4.94,;20.34,.2,;20.44,1.76,;21.62,-.62,;23.02,.08,;23.1,1.63,;21.8,2.46,;21.88,3.98,;20.59,4.84,;20.67,6.36,;22.03,7.04,;19.37,7.24,;24.28,-.76,;24.2,-2.28,;25.67,-.06,;26.96,-.9,;28.34,-.2,;28.43,1.36,;29.61,-1.02,;26.88,-2.42,;25.5,-3.1,;28.16,-3.26,;28.08,-4.8,;26.72,-5.5,;25.44,-4.66,;24.05,-5.36,;23.97,-6.91,;22.76,-4.53,;29.38,-5.66,;30.76,-4.95,;29.34,-7.2,;30.6,-8.08,;31.98,-7.39,;33.26,-8.22,;34.65,-7.51,;34.73,-5.96,;35.92,-8.35,;30.52,-9.61,;29.16,-10.29,;31.81,-10.46,;31.74,-11.98,;33.03,-12.83,;34.41,-12.12,;35.69,-12.97,;37.08,-12.26,;38.35,-13.09,;38.27,-14.62,;39.74,-12.4,;30.36,-12.67,;29.09,-11.83,;30.28,-14.22,;28.92,-14.9,;27.64,-14.07,;27.73,-12.55,;26.43,-11.71,;26.51,-10.18,;25.22,-9.32,;28.83,-16.45,;30.13,-17.3,;27.47,-17.15,;27.39,-18.7,;28.69,-19.55,;30.07,-18.84,;31.34,-19.69,;31.29,-21.18,;32.74,-18.98,;26.03,-19.4,;24.75,-18.55,;25.93,-20.94,;24.57,-21.62,;23.3,-20.8,;21.94,-21.46,;24.49,-23.17,;25.79,-24.03,;23.13,-23.87,;23.05,-25.42,;24.34,-26.27,;25.73,-25.57,;27,-26.39,;28.39,-25.7,;29.67,-26.53,;21.68,-26.1,;20.4,-25.27,;21.59,-27.66,;22.89,-28.5,;24.28,-27.81,;25.56,-28.64,;25.48,-30.17,;26.77,-31.01,;26.69,-32.54,;22.8,-30.03,;24.12,-30.87,;21.44,-30.71,;19.91,-30.09,;18.81,-31.35,;19.68,-32.79,;21.11,-32.19,;22.29,-33.19,;23.71,-32.58,;22.09,-34.72,;20.69,-35.63,;21.11,-37.25,;22.8,-37.34,;23.1,-35.82,;24.59,-35.41,;24.97,-33.92,;25.69,-36.49,;27.17,-36.08,;27.56,-34.6,;28.27,-37.17,;27.88,-38.65,;29.75,-36.76,;30.84,-37.83,;30.46,-39.33,;31.56,-40.4,;31.17,-41.89,;32.27,-42.97,;31.87,-44.46,;32.33,-37.42,;32.71,-35.93,;33.45,-38.49,;34.94,-38.1,;35.33,-36.62,;36.81,-36.21,;37.2,-34.71,;37.91,-37.28,;36.04,-39.19,;35.65,-40.67,;37.52,-38.78,;38.62,-39.85,;38.23,-41.35,;36.74,-41.75,;36.36,-43.25,;34.87,-43.66,;37.46,-44.32,;40.11,-39.44,;40.49,-37.96,;41.2,-40.53,;41.08,-42.2,;42.62,-42.84,;43.71,-41.57,;42.69,-40.39,;43.27,-38.96,;42.32,-37.76,;44.79,-38.76,;45.37,-37.32,;46.89,-37.12,;47.84,-38.32,;49.37,-38.11,;50.32,-39.3,;51.84,-39.1,;52.42,-37.66,;52.79,-40.31,;44.42,-36.11,;42.89,-36.31,;44.99,-34.69,)| Show InChI InChI=1S/C148H248N48O42/c1-79(2)68-98(130(221)183-96(47-53-113(158)203)142(233)193-64-26-41-108(193)139(230)184-97(145(236)237)38-25-63-168-148(163)164)185-123(214)85(32-14-19-57-150)172-119(210)82(7)170-137(228)106-39-28-66-195(106)144(235)109-42-29-67-196(109)141(232)95(35-17-22-60-153)182-122(213)87(34-16-21-59-152)176-135(226)103(75-198)189-128(219)93(48-54-115(205)206)178-120(211)86(33-15-20-58-151)173-121(212)88(36-23-61-166-146(159)160)174-124(215)90(44-50-110(155)200)177-126(217)92(46-52-112(157)202)181-140(231)118(81(5)6)192-129(220)89(37-24-62-167-147(161)162)175-125(216)91(45-51-111(156)201)179-133(224)101(71-84-73-165-78-169-84)188-127(218)94(49-55-116(207)208)180-138(229)107-40-27-65-194(107)143(234)104(76-199)190-131(222)99(69-80(3)4)186-132(223)100(70-83-30-11-10-12-31-83)187-136(227)105(77-238-117(209)43-13-8-9-18-56-149)191-134(225)102(74-197)171-114(204)72-154/h10-12,30-31,73,78-82,85-109,118,197-199H,8-9,13-29,32-72,74-77,149-154H2,1-7H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,226)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,227)(H,188,218)(H,189,219)(H,190,222)(H,191,225)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t82-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094060
(Ac-SS(heptyl carbonyl)FL-NH2 | CHEMBL136092)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C31H49N5O8/c1-5-6-7-8-12-15-27(39)44-19-26(36-30(42)25(18-37)33-21(4)38)31(43)35-24(17-22-13-10-9-11-14-22)29(41)34-23(28(32)40)16-20(2)3/h9-11,13-14,20,23-26,37H,5-8,12,15-19H2,1-4H3,(H2,32,40)(H,33,38)(H,34,41)(H,35,43)(H,36,42)/t23-,24-,25-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083974
(2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...)Show SMILES CN1N=C2CCN(C[C@@]2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |t:2| Show InChI InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083977
(6-Amino-2-[2-(6-chloro-2-naphthalen-2-yl-4-oxo-4H-...)Show SMILES COC(=O)C(CCCCN)NC(=O)Cn1c(nc2ccc(Cl)cc2c1=O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C27H27ClN4O4/c1-36-27(35)23(8-4-5-13-29)30-24(33)16-32-25(19-10-9-17-6-2-3-7-18(17)14-19)31-22-12-11-20(28)15-21(22)26(32)34/h2-3,6-7,9-12,14-15,23H,4-5,8,13,16,29H2,1H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50422317
(CHEMBL2310889)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:105.105,137.142,86.93,118.124,53.58,77.82,157.159,15.20,33.40,66.73,203.207,189.194,wD:178.182,223.229,185.190,62.62,112.116,11.11,126.136,96.102,166.168,44.49,24.29,211.215,143.148,194.198,227.232,(-17.34,14.48,;-16.05,13.64,;-16.13,12.1,;-14.84,11.26,;-14.92,9.73,;-13.63,8.89,;-13.71,7.35,;-12.42,6.51,;-11.05,7.21,;-12.5,4.97,;-11.21,4.13,;-11.29,2.6,;-10,1.76,;-8.62,2.46,;-8.54,3.99,;-7.33,1.62,;-7.41,.08,;-8.79,-.62,;-8.87,-2.16,;-10.24,-2.86,;-7.57,-3,;-5.96,2.32,;-4.67,1.48,;-4.75,-.06,;-3.3,2.18,;-3.22,3.71,;-1.84,4.41,;-1.76,5.95,;-.39,6.65,;-.31,8.19,;-2,1.34,;-.63,2.04,;-.55,3.57,;.66,1.2,;.58,-.34,;-.79,-1.04,;-.87,-2.58,;-2.25,-3.28,;-2.33,-4.81,;-3.7,-5.51,;-1.04,-5.65,;2.03,1.9,;3.32,1.06,;3.24,-.48,;4.69,1.76,;4.78,3.29,;6.15,3.99,;6.23,5.53,;4.94,6.37,;7.6,6.23,;5.99,.92,;7.36,1.62,;7.44,3.15,;8.65,.78,;8.57,-.76,;7.2,-1.46,;7.12,-3,;8.41,-3.84,;5.74,-3.7,;10.02,1.48,;11.31,.64,;11.23,-.9,;12.69,1.34,;13.98,.5,;15.35,1.2,;15.43,2.74,;16.64,.36,;16.56,-1.18,;15.19,-1.88,;15.11,-3.42,;13.74,-4.12,;13.65,-5.65,;12.28,-6.35,;14.95,-6.49,;18.01,1.06,;19.3,.22,;19.22,-1.32,;20.68,.92,;21.97,.08,;21.89,-1.46,;23.18,-2.3,;24.7,-2.54,;23.1,-3.84,;20.76,2.46,;22.13,3.15,;22.21,4.69,;23.42,2.32,;23.34,.78,;24.63,-.06,;26.07,.49,;27.04,-.71,;26.2,-2,;24.71,-1.6,;24.79,3.01,;26.08,2.18,;26.92,.88,;27.46,2.87,;27.54,4.41,;26.25,5.25,;26.33,6.79,;27.7,7.49,;25.04,7.63,;28.75,2.04,;30.12,2.74,;30.2,4.27,;31.41,1.9,;31.49,.36,;32.98,-.04,;33.82,1.25,;32.85,2.45,;33.25,3.94,;32.16,5.02,;34.74,4.33,;35.14,5.82,;34.05,6.91,;35.83,3.25,;37.31,3.64,;37.71,5.13,;38.4,2.55,;38,1.07,;36.52,.67,;36.12,-.82,;35.43,1.76,;39.89,2.95,;40.98,1.86,;40.58,.38,;42.47,2.26,;42.86,3.75,;41.78,4.84,;40.29,4.44,;39.2,5.53,;39.6,7.02,;41.09,7.42,;42.17,6.33,;43.55,1.17,;45.04,1.57,;45.44,3.06,;46.13,.48,;45.73,-1,;44.24,-1.4,;47.62,.88,;48.71,-.21,;48.31,-1.7,;50.19,.19,;50.59,1.68,;49.5,2.77,;51.28,-.9,;52.77,-.5,;53.17,.99,;53.86,-1.59,;55.35,-1.19,;12.77,2.87,;11.48,3.71,;14.14,3.57,;-12.66,1.9,;-12.74,.36,;-13.95,2.74,;-15.32,2.04,;-15.4,.5,;-16.78,-.2,;-16.86,-1.74,;-18.23,-2.44,;-18.31,-3.98,;-16.61,2.87,;-16.53,4.41,;-17.99,2.18,;-19.28,3.01,;-19.2,4.55,;-17.83,5.25,;-17.74,6.79,;-16.37,7.49,;-16.29,9.03,;-20.65,2.32,;-20.73,.78,;-21.94,3.15,;-22.02,4.69,;-23.51,5.09,;-24.35,3.8,;-23.38,2.6,;-23.78,1.12,;-22.69,.03,;-25.27,.72,;-26.46,1.69,;-27.75,.85,;-27.36,-.64,;-25.82,-.72,;-24.98,-2.01,;-23.44,-1.93,;-25.68,-3.38,;-24.84,-4.68,;-23.3,-4.6,;-25.54,-6.05,;-27.08,-6.13,;-24.7,-7.34,;-25.4,-8.71,;-26.94,-8.79,;-27.78,-7.5,;-29.31,-7.58,;-30.15,-6.29,;-31.69,-6.37,;-24.56,-10,;-23.02,-9.92,;-25.26,-11.38,;-24.42,-12.67,;-22.88,-12.59,;-22.05,-13.88,;-22.74,-15.25,;-20.51,-13.8,;-25.12,-14.04,;-26.66,-14.12,;-24.28,-15.33,;-24.98,-16.7,;-26.52,-16.78,;-27.22,-18.16,;-28.76,-18.24,;-29.46,-19.61,;-29.6,-16.94,;-24.14,-17.99,;-22.61,-17.91,;-24.84,-19.37,;-26.36,-19.61,;-26.6,-21.13,;-25.23,-21.83,;-24.14,-20.74,;-22.62,-20.98,;-21.65,-19.78,;-22.07,-22.42,;-20.55,-22.66,;-20,-24.1,;-20.97,-25.29,;-22.49,-25.05,;-23.46,-26.25,;-22.91,-27.69,;-23.87,-28.88,;-21.38,-27.93,;-19.58,-21.46,;-20.13,-20.02,;-18.06,-21.7,)| Show InChI InChI=1S/C149H249N47O42/c1-9-10-11-12-16-45-118(209)238-78-106(137(227)176-88(36-19-23-60-152)123(213)182-96(37-20-24-61-153)142(232)196-68-31-44-110(196)145(235)195-67-30-41-107(195)138(228)170-83(8)120(210)172-86(34-17-21-58-150)124(214)185-99(69-80(2)3)131(221)183-97(49-55-114(158)203)143(233)193-65-28-43-109(193)140(230)184-98(146(236)237)40-27-64-168-149(163)164)191-129(219)94(50-56-116(205)206)178-121(211)87(35-18-22-59-151)173-122(212)89(38-25-62-166-147(159)160)174-125(215)91(46-52-111(155)200)177-127(217)93(48-54-113(157)202)181-141(231)119(82(6)7)192-130(220)90(39-26-63-167-148(161)162)175-126(216)92(47-53-112(156)201)179-134(224)102(72-85-74-165-79-169-85)188-128(218)95(51-57-117(207)208)180-139(229)108-42-29-66-194(108)144(234)105(77-199)190-132(222)100(70-81(4)5)186-133(223)101(71-84-32-14-13-15-33-84)187-136(226)104(76-198)189-135(225)103(75-197)171-115(204)73-154/h13-15,32-33,74,79-83,86-110,119,197-199H,9-12,16-31,34-73,75-78,150-154H2,1-8H3,(H2,155,200)(H2,156,201)(H2,157,202)(H2,158,203)(H,165,169)(H,170,228)(H,171,204)(H,172,210)(H,173,212)(H,174,215)(H,175,216)(H,176,227)(H,177,217)(H,178,211)(H,179,224)(H,180,229)(H,181,231)(H,182,213)(H,183,221)(H,184,230)(H,185,214)(H,186,223)(H,187,226)(H,188,218)(H,189,225)(H,190,222)(H,191,219)(H,192,220)(H,205,206)(H,207,208)(H,236,237)(H4,159,160,166)(H4,161,162,167)(H4,163,164,168)/t83-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50049479
((S)-6-Amino-2-{(R)-2-[(S)-2-{(S)-2-[(R)-2-[(S)-2-a...)Show SMILES C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O Show InChI InChI=1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38+,39+,40-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor |
Bioorg Med Chem Lett 10: 5-8 (2000)
BindingDB Entry DOI: 10.7270/Q2DV1KDR |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094048
(CHEMBL139427 | GSS(heptyl carbonyl)-NH2)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(=O)CN)C(N)=O Show InChI InChI=1S/C16H30N4O6/c1-2-3-4-5-6-7-14(23)26-10-12(15(18)24)20-16(25)11(9-21)19-13(22)8-17/h11-12,21H,2-10,17H2,1H3,(H2,18,24)(H,19,22)(H,20,25)/t11-,12-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094050
(Ac-SS(heptyl carbonyl)F-NH2 | CHEMBL434649)Show SMILES CCCCCCCC(=O)OC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C25H38N4O7/c1-3-4-5-6-10-13-22(32)36-16-21(29-24(34)20(15-30)27-17(2)31)25(35)28-19(23(26)33)14-18-11-8-7-9-12-18/h7-9,11-12,19-21,30H,3-6,10,13-16H2,1-2H3,(H2,26,33)(H,27,31)(H,28,35)(H,29,34)/t19-,20-,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50163757
(CHEMBL428282 | Des-acyl ghrelin)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:171.183,157.163,150.152,111.120,107.109,78.87,60.67,45.52,36.43,17.17,89.96,131.140,4.4,wD:163.171,141.149,122.129,69.76,54.58,29.29,22.21,8.13,202.206,214.220,218.223,182.189,188.195,98.105,(38.25,-29.18,;38.01,-30.71,;39.22,-31.66,;36.59,-31.27,;36.35,-32.78,;34.9,-33.32,;33.69,-32.38,;33.91,-30.85,;32.25,-32.94,;32.02,-34.46,;33.22,-35.42,;32.99,-36.95,;34.19,-37.9,;33.95,-39.43,;31.05,-31.98,;29.62,-32.54,;29.38,-34.05,;28.41,-31.57,;28.65,-30.06,;26.98,-32.13,;25.78,-31.17,;26.01,-29.65,;24.34,-31.73,;24.2,-33.27,;22.51,-33.36,;21.92,-31.79,;23.22,-30.74,;23.26,-29.2,;24.61,-28.45,;21.99,-28.32,;20.62,-29.08,;19.61,-27.73,;20.57,-26.36,;22.17,-26.82,;23.45,-26,;24.84,-26.7,;23.38,-24.47,;24.68,-23.64,;26.04,-24.34,;26.12,-25.87,;27.5,-26.57,;27.57,-28.1,;22,-23.77,;21.92,-22.21,;20.57,-21.52,;23.22,-21.39,;24.59,-22.11,;25.9,-21.26,;27.25,-21.95,;28.56,-21.13,;29.92,-21.82,;23.14,-19.84,;24.42,-19.01,;25.8,-19.72,;24.34,-17.46,;22.99,-16.77,;21.7,-17.59,;25.63,-16.64,;25.56,-15.09,;24.2,-14.38,;26.85,-14.26,;28.22,-14.97,;29.53,-14.13,;30.88,-14.84,;30.97,-16.35,;32.19,-13.99,;26.77,-12.71,;28.05,-11.88,;29.43,-12.59,;27.97,-10.33,;26.62,-9.64,;26.55,-8.11,;25.17,-7.4,;25.1,-5.88,;23.72,-5.16,;29.25,-9.51,;29.18,-7.96,;27.83,-7.25,;30.48,-7.13,;31.85,-7.84,;33.15,-7,;34.51,-7.71,;35.82,-6.86,;37.17,-7.56,;37.24,-9.08,;38.48,-6.73,;30.4,-5.61,;29.02,-4.9,;27.74,-5.72,;28.94,-3.37,;30.24,-2.54,;31.6,-3.23,;32.92,-2.39,;32.84,-.84,;34.26,-3.09,;27.59,-2.64,;27.47,-1.1,;28.78,-.26,;26.1,-.39,;24.81,-1.22,;23.45,-.52,;22.14,-1.36,;22.22,-2.91,;20.78,-.67,;26.02,1.15,;24.65,1.86,;23.35,1.04,;24.57,3.38,;23.21,4.08,;21.9,3.24,;21.98,1.73,;20.56,3.95,;20.48,5.49,;19.1,6.2,;19.03,7.72,;17.65,8.43,;17.57,9.96,;18.86,10.8,;16.2,10.7,;19.24,3.1,;17.88,3.8,;17.82,5.36,;16.59,2.97,;16.65,1.44,;15.37,.62,;15.44,-.94,;16.83,-1.65,;14.16,-1.77,;15.23,3.66,;13.93,2.82,;13.99,1.3,;12.57,3.52,;12.49,5.07,;13.77,5.89,;13.85,7.43,;15.33,7.83,;16.16,6.56,;15.21,5.35,;11.28,2.68,;9.92,3.39,;9.85,4.95,;8.6,2.56,;8.67,1.03,;10.07,.31,;10.14,-1.2,;8.85,-2.02,;11.52,-1.92,;7.25,3.26,;5.94,2.43,;6.02,.89,;4.59,3.13,;4.57,4.67,;2.92,4.92,;2.19,3.42,;3.37,2.23,;3.26,.71,;4.56,-.09,;1.9,-.04,;.59,.76,;.63,2.27,;1.87,-1.58,;.53,-2.32,;-.79,-1.51,;.49,-3.85,;1.81,-4.66,;3.15,-3.92,;4.46,-4.71,;3.18,-2.38,;-.87,-4.59,;-.9,-6.13,;.42,-6.93,;-2.25,-6.88,;-3.56,-6.08,;-3.53,-4.54,;-2.19,-3.81,;-2.16,-2.27,;-3.47,-1.49,;-4.82,-2.22,;-4.84,-3.75,;-2.27,-8.42,;-3.62,-9.16,;-4.94,-8.38,;-3.64,-10.7,;-2.32,-11.49,;-.98,-10.74,;-4.98,-11.45,;-6.52,-11.47,;-7.31,-10.13,;-7.29,-12.81,;-6.5,-14.14,;-4.95,-14.13,;-8.83,-12.83,;-9.59,-14.17,;-8.8,-15.5,;-11.13,-14.19,;-11.89,-15.53,;25.88,4.22,;25.81,5.77,;27.23,3.53,;37.55,-33.75,;37.32,-35.26,;38.99,-33.19,;40.19,-34.15,;39.96,-35.67,;38.52,-36.23,;38.29,-37.76,;36.85,-38.32,;39.49,-38.71,;41.63,-33.59,;41.85,-32.08,;42.83,-34.56,;42.88,-36.23,;44.48,-36.71,;45.43,-35.33,;44.29,-34.27,;44.72,-32.78,;43.65,-31.69,;46.21,-32.42,;46.64,-30.94,;48.14,-30.58,;49.21,-31.67,;50.7,-31.31,;51.77,-32.4,;53.26,-32.04,;53.69,-30.55,;54.33,-33.14,;45.57,-29.83,;44.08,-30.18,;46,-28.36,)| Show InChI InChI=1S/C141H235N47O41/c1-73(2)62-92(123(213)175-90(42-48-107(150)196)135(225)185-58-22-37-102(185)132(222)176-91(138(228)229)34-21-57-160-141(155)156)177-116(206)79(28-11-15-51-142)164-112(202)76(7)162-130(220)100-35-24-60-187(100)137(227)103-38-25-61-188(103)134(224)89(31-14-18-54-145)174-115(205)81(30-13-17-53-144)168-128(218)97(69-190)181-121(211)87(43-49-109(198)199)170-113(203)80(29-12-16-52-143)165-114(204)82(32-19-55-158-139(151)152)166-117(207)84(39-45-104(147)193)169-119(209)86(41-47-106(149)195)173-133(223)111(75(5)6)184-122(212)83(33-20-56-159-140(153)154)167-118(208)85(40-46-105(148)194)171-126(216)95(65-78-67-157-72-161-78)180-120(210)88(44-50-110(200)201)172-131(221)101-36-23-59-186(101)136(226)99(71-192)183-124(214)93(63-74(3)4)178-125(215)94(64-77-26-9-8-10-27-77)179-129(219)98(70-191)182-127(217)96(68-189)163-108(197)66-146/h8-10,26-27,67,72-76,79-103,111,189-192H,11-25,28-66,68-71,142-146H2,1-7H3,(H2,147,193)(H2,148,194)(H2,149,195)(H2,150,196)(H,157,161)(H,162,220)(H,163,197)(H,164,202)(H,165,204)(H,166,207)(H,167,208)(H,168,218)(H,169,209)(H,170,203)(H,171,216)(H,172,221)(H,173,223)(H,174,205)(H,175,213)(H,176,222)(H,177,206)(H,178,215)(H,179,219)(H,180,210)(H,181,211)(H,182,217)(H,183,214)(H,184,212)(H,198,199)(H,200,201)(H,228,229)(H4,151,152,158)(H4,153,154,159)(H4,155,156,160)/t76-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,111-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50094063
(Ac-S(heptyl carbonyl)FL-NH2 | CHEMBL422630)Show SMILES CCCCCCCC(=O)OC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C28H44N4O6/c1-5-6-7-8-12-15-25(34)38-18-24(30-20(4)33)28(37)32-23(17-21-13-10-9-11-14-21)27(36)31-22(26(29)35)16-19(2)3/h9-11,13-14,19,22-24H,5-8,12,15-18H2,1-4H3,(H2,29,35)(H,30,33)(H,31,36)(H,32,37)/t22-,23-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga... |
J Med Chem 43: 4370-6 (2000)
BindingDB Entry DOI: 10.7270/Q2T72GP0 |
More data for this
Ligand-Target Pair | |
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