Found 113 hits with Last Name = 'redondo' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tubulin beta chain
(Sus scrofa) | BDBM50485941
(CHEMBL2181004)Show SMILES COc1ccc(CN[C@H]2CCc3cc(OC)c(OC)c(OC)c3-c3ccc(OC)c(=O)cc23)cc1 |r| Show InChI InChI=1S/C28H31NO6/c1-31-19-9-6-17(7-10-19)16-29-22-12-8-18-14-25(33-3)27(34-4)28(35-5)26(18)20-11-13-24(32-2)23(30)15-21(20)22/h6-7,9-11,13-15,22,29H,8,12,16H2,1-5H3/t22-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.0460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485945
(CHEMBL2181003)Show SMILES COc1cc2CC[C@H](NCc3ccc(cc3)[N+]([O-])=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28N2O7/c1-33-23-12-10-19-20(14-22(23)30)21(28-15-16-5-8-18(9-6-16)29(31)32)11-7-17-13-24(34-2)26(35-3)27(36-4)25(17)19/h5-6,8-10,12-14,21,28H,7,11,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.0585 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485942
(CHEMBL2181002)Show SMILES COc1cc2CC[C@H](NCc3cc(F)c(F)c(F)c3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H26F3NO5/c1-33-22-8-6-16-17(12-21(22)32)20(31-13-14-9-18(28)25(30)19(29)10-14)7-5-15-11-23(34-2)26(35-3)27(36-4)24(15)16/h6,8-12,20,31H,5,7,13H2,1-4H3/t20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.0637 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485950
(CHEMBL2181009)Show SMILES COc1cc2CC[C@H](NCc3cccc(F)c3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28FNO5/c1-31-23-11-9-19-20(14-22(23)30)21(29-15-16-6-5-7-18(28)12-16)10-8-17-13-24(32-2)26(33-3)27(34-4)25(17)19/h5-7,9,11-14,21,29H,8,10,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.122 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485944
(CHEMBL2181006)Show SMILES COc1cc2CC[C@H](NCc3ccc(Cl)cc3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28ClNO5/c1-31-23-12-10-19-20(14-22(23)30)21(29-15-16-5-8-18(28)9-6-16)11-7-17-13-24(32-2)26(33-3)27(34-4)25(17)19/h5-6,8-10,12-14,21,29H,7,11,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.127 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485943
(CHEMBL2181001)Show SMILES COc1cc2CC[C@H](NCc3cc(F)cc(F)c3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H27F2NO5/c1-32-23-8-6-19-20(13-22(23)31)21(30-14-15-9-17(28)12-18(29)10-15)7-5-16-11-24(33-2)26(34-3)27(35-4)25(16)19/h6,8-13,21,30H,5,7,14H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.131 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485946
(CHEMBL2181000)Show SMILES COc1cc2CC[C@H](NCc3ccc(F)c(F)c3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H27F2NO5/c1-32-23-10-7-17-18(13-22(23)31)21(30-14-15-5-8-19(28)20(29)11-15)9-6-16-12-24(33-2)26(34-3)27(35-4)25(16)17/h5,7-8,10-13,21,30H,6,9,14H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485947
(CHEMBL2181008)Show SMILES COc1cc2CC[C@H](NCc3ccc(F)cc3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28FNO5/c1-31-23-12-10-19-20(14-22(23)30)21(29-15-16-5-8-18(28)9-6-16)11-7-17-13-24(32-2)26(33-3)27(34-4)25(17)19/h5-6,8-10,12-14,21,29H,7,11,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.183 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485949
(CHEMBL2180999)Show SMILES COc1cc2CC[C@H](NCc3cccc(F)c3F)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H27F2NO5/c1-32-22-11-9-17-18(13-21(22)31)20(30-14-16-6-5-7-19(28)25(16)29)10-8-15-12-23(33-2)26(34-3)27(35-4)24(15)17/h5-7,9,11-13,20,30H,8,10,14H2,1-4H3/t20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.198 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485948
(CHEMBL2181007)Show SMILES COc1cc2CC[C@H](NCc3ccc(I)cc3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28INO5/c1-31-23-12-10-19-20(14-22(23)30)21(29-15-16-5-8-18(28)9-6-16)11-7-17-13-24(32-2)26(33-3)27(34-4)25(17)19/h5-6,8-10,12-14,21,29H,7,11,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50485940
(CHEMBL2181005)Show SMILES COc1cc2CC[C@H](NCc3ccc(Br)cc3)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C27H28BrNO5/c1-31-23-12-10-19-20(14-22(23)30)21(29-15-16-5-8-18(28)9-6-16)11-7-17-13-24(32-2)26(33-3)27(34-4)25(17)19/h5-6,8-10,12-14,21,29H,7,11,15H2,1-4H3/t21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.367 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | |
Tubulin beta chain
(Sus scrofa) | BDBM50014846
((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford
Curated by ChEMBL
| Assay Description Binding affinity to pig brain tubulin |
J Med Chem 55: 11062-6 (2012)
Article DOI: 10.1021/jm301151t BindingDB Entry DOI: 10.7270/Q22V2K0N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385903
(CHEMBL2041614)Show SMILES COc1cc(CNC(=O)c2ccc(o2)-c2ccc(C)cc2[N+]([O-])=O)cc(OC)c1OC Show InChI InChI=1S/C22H22N2O7/c1-13-5-6-15(16(9-13)24(26)27)17-7-8-18(31-17)22(25)23-12-14-10-19(28-2)21(30-4)20(11-14)29-3/h5-11H,12H2,1-4H3,(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008422
(CHEMBL3235552)Show InChI InChI=1S/C17H13F3N2O2S/c1-24-13-5-3-2-4-10(13)8-15(23)22-16-21-12-7-6-11(17(18,19)20)9-14(12)25-16/h2-7,9H,8H2,1H3,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008512
(CHEMBL3235572)Show SMILES COc1cc(CC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C19H17F3N2O4S/c1-26-13-6-10(7-14(27-2)17(13)28-3)8-16(25)24-18-23-12-5-4-11(19(20,21)22)9-15(12)29-18/h4-7,9H,8H2,1-3H3,(H,23,24,25) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008401
(CHEMBL3235538)Show InChI InChI=1S/C16H10ClF3N2OS/c17-11-3-1-2-9(6-11)7-14(23)22-15-21-12-5-4-10(16(18,19)20)8-13(12)24-15/h1-6,8H,7H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008500
(CHEMBL3235560)Show InChI InChI=1S/C17H13F3N2O2S/c1-24-12-5-2-10(3-6-12)8-15(23)22-16-21-13-7-4-11(17(18,19)20)9-14(13)25-16/h2-7,9H,8H2,1H3,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008496
(CHEMBL3235556)Show InChI InChI=1S/C17H13F3N2O2S/c1-24-12-4-2-3-10(7-12)8-15(23)22-16-21-13-6-5-11(17(18,19)20)9-14(13)25-16/h2-7,9H,8H2,1H3,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008503
(CHEMBL3235563)Show InChI InChI=1S/C16H11F3N2OS/c17-16(18,19)11-6-7-12-13(9-11)23-15(20-12)21-14(22)8-10-4-2-1-3-5-10/h1-7,9H,8H2,(H,20,21,22) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008504
(CHEMBL3235564)Show SMILES FC(F)(F)c1ccc2nc(NC(=O)Cc3ccc(Cl)c(Cl)c3)sc2c1 Show InChI InChI=1S/C16H9Cl2F3N2OS/c17-10-3-1-8(5-11(10)18)6-14(24)23-15-22-12-4-2-9(16(19,20)21)7-13(12)25-15/h1-5,7H,6H2,(H,22,23,24) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008411
(CHEMBL3235545)Show InChI InChI=1S/C16H10ClF3N2OS/c17-11-4-1-9(2-5-11)7-14(23)22-15-21-12-6-3-10(16(18,19)20)8-13(12)24-15/h1-6,8H,7H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008406
(CHEMBL3235542)Show InChI InChI=1S/C16H10ClF3N2OS/c17-11-4-2-1-3-9(11)7-14(23)22-15-21-12-6-5-10(16(18,19)20)8-13(12)24-15/h1-6,8H,7H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008509
(CHEMBL3235569)Show SMILES COc1cc(CC(=O)Nc2nc3ccc(OC(F)(F)F)cc3s2)cc(OC)c1OC Show InChI InChI=1S/C19H17F3N2O5S/c1-26-13-6-10(7-14(27-2)17(13)28-3)8-16(25)24-18-23-12-5-4-11(9-15(12)30-18)29-19(20,21)22/h4-7,9H,8H2,1-3H3,(H,23,24,25) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008399
(CHEMBL3235535)Show InChI InChI=1S/C16H13ClN2OS/c1-10-5-6-13-14(7-10)21-16(18-13)19-15(20)9-11-3-2-4-12(17)8-11/h2-8H,9H2,1H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008499
(CHEMBL3235559)Show SMILES FC(F)(F)c1cccc(CC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)c1 Show InChI InChI=1S/C17H10F6N2OS/c18-16(19,20)10-3-1-2-9(6-10)7-14(26)25-15-24-12-5-4-11(17(21,22)23)8-13(12)27-15/h1-6,8H,7H2,(H,24,25,26) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50277784
(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)Show InChI InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008508
(CHEMBL3235568)Show SMILES COc1ccc(OC)c(CC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)c1 Show InChI InChI=1S/C18H15F3N2O3S/c1-25-12-4-6-14(26-2)10(7-12)8-16(24)23-17-22-13-5-3-11(18(19,20)21)9-15(13)27-17/h3-7,9H,8H2,1-2H3,(H,22,23,24) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008417
(CHEMBL3235548)Show InChI InChI=1S/C16H13BrN2O2S/c1-21-13-5-3-2-4-10(13)8-15(20)19-16-18-12-7-6-11(17)9-14(12)22-16/h2-7,9H,8H2,1H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008420
(CHEMBL3235551)Show InChI InChI=1S/C17H16N2O2S/c1-11-7-8-13-15(9-11)22-17(18-13)19-16(20)10-12-5-3-4-6-14(12)21-2/h3-9H,10H2,1-2H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008418
(CHEMBL3235549)Show InChI InChI=1S/C16H13ClN2O2S/c1-21-13-5-3-2-4-10(13)8-15(20)19-16-18-12-7-6-11(17)9-14(12)22-16/h2-7,9H,8H2,1H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM49375
(MLS000527505 | N-(1,3-benzothiazol-2-yl)-2-phenyl-...)Show InChI InChI=1S/C15H12N2OS/c18-14(10-11-6-2-1-3-7-11)17-15-16-12-8-4-5-9-13(12)19-15/h1-9H,10H2,(H,16,17,18) | PDB
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008497
(CHEMBL3235557)Show InChI InChI=1S/C17H16N2O3S/c1-21-12-5-3-4-11(8-12)9-16(20)19-17-18-14-7-6-13(22-2)10-15(14)23-17/h3-8,10H,9H2,1-2H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008514
(CHEMBL3235573)Show InChI InChI=1S/C16H17F3N2OS/c17-16(18,19)11-6-7-12-13(9-11)23-15(20-12)21-14(22)8-10-4-2-1-3-5-10/h6-7,9-10H,1-5,8H2,(H,20,21,22) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008515
(CHEMBL3235574)Show InChI InChI=1S/C14H15F3N2OS/c1-13(2,3)7-11(20)19-12-18-9-5-4-8(14(15,16)17)6-10(9)21-12/h4-6H,7H2,1-3H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50494447
(CHEMBL3085803)Show SMILES Fc1cccc(F)c1-n1c(=S)[nH]c2ccccc2c1=S |(38.34,-18.49,;38.35,-16.95,;39.68,-16.19,;39.7,-14.65,;38.36,-13.88,;37.02,-14.64,;35.69,-13.86,;37.02,-16.18,;35.69,-16.94,;35.69,-18.48,;37.02,-19.25,;34.36,-19.24,;33.03,-18.48,;31.71,-19.25,;30.37,-18.48,;30.37,-16.94,;31.71,-16.17,;33.03,-16.94,;34.36,-16.16,;34.36,-14.62,)| Show InChI InChI=1S/C14H8F2N2S2/c15-9-5-3-6-10(16)12(9)18-13(19)8-4-1-2-7-11(8)17-14(18)20/h1-7H,(H,17,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 using [3H]AMP after 20 mins by scintillation proximity assay |
Eur J Med Chem 70: 781-8 (2013)
Article DOI: 10.1016/j.ejmech.2013.10.035 BindingDB Entry DOI: 10.7270/Q2CR5X88 |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008402
(CHEMBL3235539)Show InChI InChI=1S/C16H13ClN2O2S/c1-21-12-5-6-13-14(9-12)22-16(18-13)19-15(20)8-10-3-2-4-11(17)7-10/h2-7,9H,8H2,1H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008403
(CHEMBL3235540)Show SMILES FC(F)(F)Oc1ccc2nc(NC(=O)Cc3cccc(Cl)c3)sc2c1 Show InChI InChI=1S/C16H10ClF3N2O2S/c17-10-3-1-2-9(6-10)7-14(23)22-15-21-12-5-4-11(8-13(12)25-15)24-16(18,19)20/h1-6,8H,7H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008501
(CHEMBL3235561)Show InChI InChI=1S/C17H16N2O3S/c1-21-12-5-3-11(4-6-12)9-16(20)19-17-18-14-8-7-13(22-2)10-15(14)23-17/h3-8,10H,9H2,1-2H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385909
(CHEMBL2041586)Show SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)OCc1ccc(o1)-c1ccc(cc1C)[N+]([O-])=O Show InChI InChI=1S/C25H27NO8/c1-5-30-22-13-17(14-23(31-6-2)24(22)32-7-3)25(27)33-15-19-9-11-21(34-19)20-10-8-18(26(28)29)12-16(20)4/h8-14H,5-7,15H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008507
(CHEMBL3235567)Show SMILES FC(F)(F)Oc1ccc2nc(NC(=O)Cc3ccc(Cl)c(Cl)c3)sc2c1 Show InChI InChI=1S/C16H9Cl2F3N2O2S/c17-10-3-1-8(5-11(10)18)6-14(24)23-15-22-12-4-2-9(7-13(12)26-15)25-16(19,20)21/h1-5,7H,6H2,(H,22,23,24) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM350899
(2-Benzylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline...)Show InChI InChI=1S/C21H16N2OS/c24-20-18-13-7-8-14-19(18)22-21(23(20)17-11-5-2-6-12-17)25-15-16-9-3-1-4-10-16/h1-14H,15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 using [3H]AMP after 20 mins by scintillation proximity assay |
Eur J Med Chem 70: 781-8 (2013)
Article DOI: 10.1016/j.ejmech.2013.10.035 BindingDB Entry DOI: 10.7270/Q2CR5X88 |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008425
(CHEMBL3235554)Show InChI InChI=1S/C17H13F3N2O3S/c1-24-13-5-3-2-4-10(13)8-15(23)22-16-21-12-7-6-11(9-14(12)26-16)25-17(18,19)20/h2-7,9H,8H2,1H3,(H,21,22,23) | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008412
(CHEMBL3235546)Show InChI InChI=1S/C16H13ClN2O2S/c1-21-12-6-7-13-14(9-12)22-16(18-13)19-15(20)8-10-2-4-11(17)5-3-10/h2-7,9H,8H2,1H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008362
(CHEMBL3235183)Show InChI InChI=1S/C15H11ClN2OS/c16-11-5-3-4-10(8-11)9-14(19)18-15-17-12-6-1-2-7-13(12)20-15/h1-8H,9H2,(H,17,18,19) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM77437
(1-({[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]...)Show SMILES CCOC(=O)c1sc(NC(=O)C(CC)OC(=O)C(CC(C)C)NC(=O)c2ccccc2)nc1C Show InChI InChI=1S/C24H31N3O6S/c1-6-18(21(29)27-24-25-15(5)19(34-24)23(31)32-7-2)33-22(30)17(13-14(3)4)26-20(28)16-11-9-8-10-12-16/h8-12,14,17-18H,6-7,13H2,1-5H3,(H,26,28)(H,25,27,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50385910
(CHEMBL2041587)Show SMILES CC1CCCCC1NC(=O)C(N(CCc1ccccc1Cl)C(=O)CCl)c1ccccc1Cl Show InChI InChI=1S/C25H29Cl3N2O2/c1-17-8-2-7-13-22(17)29-25(32)24(19-10-4-6-12-21(19)28)30(23(31)16-26)15-14-18-9-3-5-11-20(18)27/h3-6,9-12,17,22,24H,2,7-8,13-16H2,1H3,(H,29,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A1 |
J Med Chem 55: 3274-84 (2012)
Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008498
(CHEMBL3235558)Show InChI InChI=1S/C18H18N2O3S/c1-3-23-14-7-8-15-16(11-14)24-18(19-15)20-17(21)10-12-5-4-6-13(9-12)22-2/h4-9,11H,3,10H2,1-2H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM50008516
(IC261)Show SMILES COc1cc(OC)c(C=C2C(O)=Nc3ccccc23)c(OC)c1 |c:11| Show InChI InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay |
J Med Chem 57: 2755-72 (2014)
Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50359737
(CHEMBL1927722)Show InChI InChI=1S/C14H10N2S2/c17-13-11-8-4-5-9-12(11)15-14(18)16(13)10-6-2-1-3-7-10/h1-9H,(H,15,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
Eur J Med Chem 47: 175-85 (2012)
Article DOI: 10.1016/j.ejmech.2011.10.040 BindingDB Entry DOI: 10.7270/Q20G3KJS |
More data for this Ligand-Target Pair | |