Compile Data Set for Download or QSAR

Found 261 hits with Last Name = 'sanganee' and Initial = 'hj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357127 (CHEMBL1917440) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(cccc2n1CC(O)=O)-c1cnccn1 Show InChI InChI=1S/C21H16ClN3O2S/c1-13-21(28-15-7-5-14(22)6-8-15)20-16(17-11-23-9-10-24-17)3-2-4-18(20)25(13)12-19(26)27/h2-11H,12H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357125 (CHEMBL1917438) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(cccc2n1CC(O)=O)-c1ccccc1 Show InChI InChI=1S/C23H18ClNO2S/c1-15-23(28-18-12-10-17(24)11-13-18)22-19(16-6-3-2-4-7-16)8-5-9-20(22)25(15)14-21(26)27/h2-13H,14H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357112 (CHEMBL1917427) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(C)c(F)ccc2n1CC(O)=O Show InChI InChI=1S/C18H15ClFNO2S/c1-10-14(20)7-8-15-17(10)18(11(2)21(15)9-16(22)23)24-13-5-3-12(19)4-6-13/h3-8H,9H2,1-2H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357105 (CHEMBL1917443) Show SMILES Cc1c(Sc2ccc(cc2)S(C)(=O)=O)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C19H19NO4S2/c1-12-4-9-17-16(10-12)19(13(2)20(17)11-18(21)22)25-14-5-7-15(8-6-14)26(3,23)24/h4-10H,11H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357149 (CHEMBL1917426) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C17H13ClFNO2S/c1-10-17(23-13-5-2-11(18)3-6-13)14-8-12(19)4-7-15(14)20(10)9-16(21)22/h2-8H,9H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357104 (CHEMBL1917433) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(O)=O Show InChI InChI=1S/C18H17ClN2O4S2/c1-11-18(26-13-8-6-12(19)7-9-13)17-14(20-27(2,24)25)4-3-5-15(17)21(11)10-16(22)23/h3-9,20H,10H2,1-2H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50049478 (1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...) Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 Show InChI InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50049478 (1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...) Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 Show InChI InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357129 (CHEMBL1917442) Show SMILES Cc1c(Sc2ccccc2Cl)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C18H16ClNO2S/c1-11-7-8-15-13(9-11)18(12(2)20(15)10-17(21)22)23-16-6-4-3-5-14(16)19/h3-9H,10H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357128 (CHEMBL1917441) Show SMILES Cc1c(Sc2cccc(Cl)c2)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C18H16ClNO2S/c1-11-6-7-16-15(8-11)18(12(2)20(16)10-17(21)22)23-14-5-3-4-13(19)9-14/h3-9H,10H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357142 (CHEMBL1917456) Show SMILES Cc1c(Oc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(O)=O Show InChI InChI=1S/C18H17ClN2O5S/c1-11-18(26-13-8-6-12(19)7-9-13)17-14(20-27(2,24)25)4-3-5-15(17)21(11)10-16(22)23/h3-9,20H,10H2,1-2H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357144 (CHEMBL1917458) Show SMILES CCS(=O)(=O)c1ccc(Oc2c(C)n(CC(O)=O)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C20H18F3NO5S/c1-3-30(27,28)15-7-5-14(6-8-15)29-19-12(2)24(11-18(25)26)17-9-4-13(10-16(17)19)20(21,22)23/h4-10H,3,11H2,1-2H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357124 (CHEMBL1917437) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(cccc2n1CC(O)=O)-c1nccs1 Show InChI InChI=1S/C20H15ClN2O2S2/c1-12-19(27-14-7-5-13(21)6-8-14)18-15(20-22-9-10-26-20)3-2-4-16(18)23(12)11-17(24)25/h2-10H,11H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357126 (CHEMBL1917439) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2cc(ccc2n1CC(O)=O)-c1ccccc1 Show InChI InChI=1S/C23H18ClNO2S/c1-15-23(28-19-10-8-18(24)9-11-19)20-13-17(16-5-3-2-4-6-16)7-12-21(20)25(15)14-22(26)27/h2-13H,14H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357146 (CHEMBL1917460) Show SMILES Cc1c(Oc2ccc(Cl)cc2)c2c(cccc2n1CC(O)=O)-c1ccccc1 Show InChI InChI=1S/C23H18ClNO3/c1-15-23(28-18-12-10-17(24)11-13-18)22-19(16-6-3-2-4-7-16)8-5-9-20(22)25(15)14-21(26)27/h2-13H,14H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280783 (CHEMBL4164328) Show SMILES CN(C)CCNC(=O)[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2ccccc2[nH]1 |r| Show InChI InChI=1S/C23H26N4O2/c1-27(2)12-11-24-23(29)21-17-9-5-3-7-15(17)13-19(21)26-22(28)20-14-16-8-4-6-10-18(16)25-20/h3-10,14,19,21,25H,11-13H2,1-2H3,(H,24,29)(H,26,28)/t19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro inhibition of dihydrofolate reductase enzymes in Neisseria gonorrhoeae				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280783 (CHEMBL4164328) Show SMILES CN(C)CCNC(=O)[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2ccccc2[nH]1 |r| Show InChI InChI=1S/C23H26N4O2/c1-27(2)12-11-24-23(29)21-17-9-5-3-7-15(17)13-19(21)26-22(28)20-14-16-8-4-6-10-18(16)25-20/h3-10,14,19,21,25H,11-13H2,1-2H3,(H,24,29)(H,26,28)/t19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357102 (CHEMBL1914489) Show SMILES CC(=O)Nc1cccc2n(CC(O)=O)c(C)c(Sc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C19H17ClN2O3S/c1-11-19(26-14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357140 (CHEMBL1917454) Show SMILES Cc1c(Oc2ccc(Cl)cc2)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C17H13ClFNO3/c1-10-17(23-13-5-2-11(18)3-6-13)14-8-12(19)4-7-15(14)20(10)9-16(21)22/h2-8H,9H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357113 (CHEMBL1917428) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(C#N)c(Cl)ccc2n1CC(O)=O Show InChI InChI=1S/C18H12Cl2N2O2S/c1-10-18(25-12-4-2-11(19)3-5-12)17-13(8-21)14(20)6-7-15(17)22(10)9-16(23)24/h2-7H,9H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357135 (CHEMBL1917449) Show SMILES CC(=O)Nc1cccc2n(CC(O)=O)c(C)c(c12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H17ClN2O5S/c1-11-19(28(26,27)14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357133 (CHEMBL1917447) Show SMILES Cc1c(c2cc(F)ccc2n1CC(O)=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H13ClFNO4S/c1-10-17(25(23,24)13-5-2-11(18)3-6-13)14-8-12(19)4-7-15(14)20(10)9-16(21)22/h2-8H,9H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357130 (CHEMBL1917444) Show SMILES COc1ccc(Sc2c(C)n(CC(O)=O)c3ccc(C)cc23)cc1 Show InChI InChI=1S/C19H19NO3S/c1-12-4-9-17-16(10-12)19(13(2)20(17)11-18(21)22)24-15-7-5-14(23-3)6-8-15/h4-10H,11H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357136 (CHEMBL1917450) Show SMILES Cc1c(c2c(NS(C)(=O)=O)cccc2n1CC(O)=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2O6S2/c1-11-18(29(26,27)13-8-6-12(19)7-9-13)17-14(20-28(2,24)25)4-3-5-15(17)21(11)10-16(22)23/h3-9,20H,10H2,1-2H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357102 (CHEMBL1914489) Show SMILES CC(=O)Nc1cccc2n(CC(O)=O)c(C)c(Sc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C19H17ClN2O3S/c1-11-19(26-14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity against human CRTh2 receptor in human eosinophils assessed as inhibition of DK-PGD2-induced CD11b expression				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357141 (CHEMBL1917455) Show SMILES Cc1c(Oc2ccc(Cl)cc2)c2cc(ccc2n1CC(O)=O)C(F)(F)F Show InChI InChI=1S/C18H13ClF3NO3/c1-10-17(26-13-5-3-12(19)4-6-13)14-8-11(18(20,21)22)2-7-15(14)23(10)9-16(24)25/h2-8H,9H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357117 (CHEMBL1917432) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(cccc2n1CC(O)=O)S(C)(=O)=O Show InChI InChI=1S/C18H16ClNO4S2/c1-11-18(25-13-8-6-12(19)7-9-13)17-14(20(11)10-16(21)22)4-3-5-15(17)26(2,23)24/h3-9H,10H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280846 (CHEMBL4171914) Show SMILES Cn1ccc2c(F)c(ccc12)C(=O)N[C@H]1Cc2ccccc2[C@@H]1NC(=O)c1cnccc1N |r| Show InChI InChI=1S/C25H22FN5O2/c1-31-11-9-16-21(31)7-6-17(22(16)26)24(32)29-20-12-14-4-2-3-5-15(14)23(20)30-25(33)18-13-28-10-8-19(18)27/h2-11,13,20,23H,12H2,1H3,(H2,27,28)(H,29,32)(H,30,33)/t20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in rats				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280848 (CHEMBL4170481) Show SMILES CN1CCO[C@@H](C1)C(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C25H28N4O3/c1-15-7-8-19-17(11-15)13-21(26-19)24(30)27-20-12-16-5-3-4-6-18(16)23(20)28-25(31)22-14-29(2)9-10-32-22/h3-8,11,13,20,22-23,26H,9-10,12,14H2,1-2H3,(H,27,30)(H,28,31)/t20-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in rats				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357120 (CHEMBL1917419) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2cc(Cl)ccc2n1CC(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-10-17(23-13-5-2-11(18)3-6-13)14-8-12(19)4-7-15(14)20(10)9-16(21)22/h2-8H,9H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280781 (CHEMBL4164040) Show SMILES Nc1ccncc1C(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2c(F)cc(F)cc2[nH]1 |r| Show InChI InChI=1S/C24H19F2N5O2/c25-13-8-17(26)15-10-21(29-19(15)9-13)24(33)30-20-7-12-3-1-2-4-14(12)22(20)31-23(32)16-11-28-6-5-18(16)27/h1-6,8-11,20,22,29H,7H2,(H2,27,28)(H,30,33)(H,31,32)/t20-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro inhibition of dihydrofolate reductase of Escherichia coli				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280780 (CHEMBL4169979) Show SMILES CN(C)CCN(C)C(=O)[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C25H30N4O2/c1-16-9-10-20-18(13-16)15-22(26-20)24(30)27-21-14-17-7-5-6-8-19(17)23(21)25(31)29(4)12-11-28(2)3/h5-10,13,15,21,23,26H,11-12,14H2,1-4H3,(H,27,30)/t21-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280846 (CHEMBL4171914) Show SMILES Cn1ccc2c(F)c(ccc12)C(=O)N[C@H]1Cc2ccccc2[C@@H]1NC(=O)c1cnccc1N |r| Show InChI InChI=1S/C25H22FN5O2/c1-31-11-9-16-21(31)7-6-17(22(16)26)24(32)29-20-12-14-4-2-3-5-15(14)23(20)30-25(33)18-13-28-10-8-19(18)27/h2-11,13,20,23H,12H2,1H3,(H2,27,28)(H,29,32)(H,30,33)/t20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in rats				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280780 (CHEMBL4169979) Show SMILES CN(C)CCN(C)C(=O)[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C25H30N4O2/c1-16-9-10-20-18(13-16)15-22(26-20)24(30)27-21-14-17-7-5-6-8-19(17)23(21)25(31)29(4)12-11-28(2)3/h5-10,13,15,21,23,26H,11-12,14H2,1-4H3,(H,27,30)/t21-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280848 (CHEMBL4170481) Show SMILES CN1CCO[C@@H](C1)C(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C25H28N4O3/c1-15-7-8-19-17(11-15)13-21(26-19)24(30)27-20-12-16-5-3-4-6-18(16)23(20)28-25(31)22-14-29(2)9-10-32-22/h3-8,11,13,20,22-23,26H,9-10,12,14H2,1-2H3,(H,27,30)(H,28,31)/t20-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280781 (CHEMBL4164040) Show SMILES Nc1ccncc1C(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2c(F)cc(F)cc2[nH]1 |r| Show InChI InChI=1S/C24H19F2N5O2/c25-13-8-17(26)15-10-21(29-19(15)9-13)24(33)30-20-7-12-3-1-2-4-14(12)22(20)31-23(32)16-11-28-6-5-18(16)27/h1-6,8-11,20,22,29H,7H2,(H2,27,28)(H,30,33)(H,31,32)/t20-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357103 (CHEMBL1917418) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C18H16ClNO2S/c1-11-3-8-16-15(9-11)18(12(2)20(16)10-17(21)22)23-14-6-4-13(19)5-7-14/h3-9H,10H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280852 (CHEMBL4171040) Show SMILES CN(C)CCC(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C24H28N4O2/c1-15-8-9-19-17(12-15)14-21(25-19)24(30)26-20-13-16-6-4-5-7-18(16)23(20)27-22(29)10-11-28(2)3/h4-9,12,14,20,23,25H,10-11,13H2,1-3H3,(H,26,30)(H,27,29)/t20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280852 (CHEMBL4171040) Show SMILES CN(C)CCC(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1 |r| Show InChI InChI=1S/C24H28N4O2/c1-15-8-9-19-17(12-15)14-21(25-19)24(30)26-20-13-16-6-4-5-7-18(16)23(20)27-22(29)10-11-28(2)3/h4-9,12,14,20,23,25H,10-11,13H2,1-3H3,(H,26,30)(H,27,29)/t20-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in rats				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357143 (CHEMBL1917457) Show SMILES CC(=O)Nc1cccc2n(CC(O)=O)c(C)c(Oc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C19H17ClN2O4/c1-11-19(26-14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50413241 (CHEMBL513412) Show SMILES COc1ccc(N(C(C(=O)NC[C@@H](C)O)c2ccccc2F)C(=O)c2occc2C)c(OC)c1 |r| Show InChI InChI=1S/C25H27FN2O6/c1-15-11-12-34-23(15)25(31)28(20-10-9-17(32-3)13-21(20)33-4)22(24(30)27-14-16(2)29)18-7-5-6-8-19(18)26/h5-13,16,22,29H,14H2,1-4H3,(H,27,30)/t16-,22?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in HEK cells assessed as inhibition of C5a-induced calcium mobilization				Bioorg Med Chem Lett 19: 1143-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.104 BindingDB Entry DOI: 10.7270/Q2Q241G1
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50083974 (2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...) Show SMILES CN1N=C2CCN(C[C@@]2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |t:2| Show InChI InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357119 (CHEMBL1917417) Show SMILES Cc1c(Sc2ccccc2)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C18H17NO2S/c1-12-8-9-16-15(10-12)18(13(2)19(16)11-17(20)21)22-14-6-4-3-5-7-14/h3-10H,11H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50083974 (2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...) Show SMILES CN1N=C2CCN(C[C@@]2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |t:2| Show InChI InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro inhibition of dihydrofolate reductase enzymes in Neisseria gonorrhoeae				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357119 (CHEMBL1917417) Show SMILES Cc1c(Sc2ccccc2)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C18H17NO2S/c1-12-8-9-16-15(10-12)18(13(2)19(16)11-17(20)21)22-14-6-4-3-5-7-14/h3-10H,11H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium flux				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357111 (CHEMBL1917425) Show SMILES Cc1c(Sc2ccc(Cl)cc2)c2c(Cl)cccc2n1CC(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-10-17(23-12-7-5-11(18)6-8-12)16-13(19)3-2-4-14(16)20(10)9-15(21)22/h2-8H,9H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50413240 (CHEMBL471412) Show SMILES COc1ccc(N(C(C(=O)NC2CCCC2)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1 Show InChI InChI=1S/C28H29FN2O4/c1-34-21-16-17-24(25(18-21)35-2)31(28(33)19-10-4-3-5-11-19)26(22-14-8-9-15-23(22)29)27(32)30-20-12-6-7-13-20/h3-5,8-11,14-18,20,26H,6-7,12-13H2,1-2H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in HEK cells assessed as inhibition of C5a-induced calcium mobilization				Bioorg Med Chem Lett 19: 1143-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.104 BindingDB Entry DOI: 10.7270/Q2Q241G1
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50357132 (CHEMBL1917446) Show SMILES Cc1c(c2cc(C)ccc2n1CC(O)=O)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H16ClNO4S/c1-11-3-8-16-15(9-11)18(12(2)20(16)10-17(21)22)25(23,24)14-6-4-13(19)5-7-14/h3-9H,10H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor				Bioorg Med Chem Lett 21: 6288-92 (2011) Article DOI: 10.1016/j.bmcl.2011.08.124 BindingDB Entry DOI: 10.7270/Q29P3225
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50280785 (CHEMBL4168863) Show SMILES CN1CCC[C@H]1CC(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1ccc2n(C)ccc2c1 |r| Show InChI InChI=1S/C26H30N4O2/c1-29-12-5-7-20(29)16-24(31)28-25-21-8-4-3-6-17(21)15-22(25)27-26(32)19-9-10-23-18(14-19)11-13-30(23)2/h3-4,6,8-11,13-14,20,22,25H,5,7,12,15-16H2,1-2H3,(H,27,32)(H,28,31)/t20-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay				J Med Chem 61: 5974-5987 (2018) Article DOI: 10.1021/acs.jmedchem.8b00322 BindingDB Entry DOI: 10.7270/Q2WD433X
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50413240 (CHEMBL471412) Show SMILES COc1ccc(N(C(C(=O)NC2CCCC2)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1 Show InChI InChI=1S/C28H29FN2O4/c1-34-21-16-17-24(25(18-21)35-2)31(28(33)19-10-4-3-5-11-19)26(22-14-8-9-15-23(22)29)27(32)30-20-12-6-7-13-20/h3-5,8-11,14-18,20,26H,6-7,12-13H2,1-2H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [Alexa647]C5a from human recombinant C5a receptor expressed in HEK cells by membrane binding assay in presence of [35S]GTPgammaS				Bioorg Med Chem Lett 19: 1143-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.104 BindingDB Entry DOI: 10.7270/Q2Q241G1
					More data for this Ligand-Target Pair

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