Compile Data Set for Download or QSAR

Found 246 hits with Last Name = 'silver' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10882 (6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...) Show SMILES CCOc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10882 (6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...) Show SMILES CCOc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM10875 (5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...) Show SMILES NS(=O)(=O)c1nnc(s1)-c1ccccc1Cl Show InChI InChI=1S/C8H6ClN3O2S2/c9-6-4-2-1-3-5(6)7-11-12-8(15-7)16(10,13)14/h1-4H,(H2,10,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10875 (5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...) Show SMILES NS(=O)(=O)c1nnc(s1)-c1ccccc1Cl Show InChI InChI=1S/C8H6ClN3O2S2/c9-6-4-2-1-3-5(6)7-11-12-8(15-7)16(10,13)14/h1-4H,(H2,10,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10875 (5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...) Show SMILES NS(=O)(=O)c1nnc(s1)-c1ccccc1Cl Show InChI InChI=1S/C8H6ClN3O2S2/c9-6-4-2-1-3-5(6)7-11-12-8(15-7)16(10,13)14/h1-4H,(H2,10,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM92939 (Methazolamide, MZM) Show SMILES CC1N=C(S\C1=N\C(C)=O)S(N)(=O)=O |c:2| Show InChI InChI=1S/C6H9N3O3S2/c1-3-5(9-4(2)10)13-6(8-3)14(7,11)12/h3H,1-2H3,(H2,7,11,12)/b9-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	10.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM92939 (Methazolamide, MZM) Show SMILES CC1N=C(S\C1=N\C(C)=O)S(N)(=O)=O |c:2| Show InChI InChI=1S/C6H9N3O3S2/c1-3-5(9-4(2)10)13-6(8-3)14(7,11)12/h3H,1-2H3,(H2,7,11,12)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM92939 (Methazolamide, MZM) Show SMILES CC1N=C(S\C1=N\C(C)=O)S(N)(=O)=O |c:2| Show InChI InChI=1S/C6H9N3O3S2/c1-3-5(9-4(2)10)13-6(8-3)14(7,11)12/h3H,1-2H3,(H2,7,11,12)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162903 (CHEMBL359855 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES CC1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C21H21FN2O4S/c1-13-2-8-19-17(10-13)18-11-15(5-9-20(18)24(19)12-21(25)26)23-29(27,28)16-6-3-14(22)4-7-16/h3-7,9,11,13,23H,2,8,10,12H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 in hTP binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162894 (CHEMBL361972 | [2-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)CN1C2CCCCCC2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H23FN2O4S/c22-14-6-9-16(10-7-14)29(27,28)23-15-8-11-20-18(12-15)17-4-2-1-3-5-19(17)24(20)13-21(25)26/h6-12,17,19,23H,1-5,13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162917 (CHEMBL360288 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C20H19FN2O4S/c21-13-5-8-15(9-6-13)28(26,27)22-14-7-10-19-17(11-14)16-3-1-2-4-18(16)23(19)12-20(24)25/h5-11,22H,1-4,12H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162891 (CHEMBL179980 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCC(Cc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12)c1ccccc1 Show InChI InChI=1S/C26H23FN2O4S/c27-19-7-10-21(11-8-19)34(32,33)28-20-9-13-25-23(15-20)22-14-18(17-4-2-1-3-5-17)6-12-24(22)29(25)16-26(30)31/h1-5,7-11,13,15,18,28H,6,12,14,16H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162896 (CHEMBL369330 | [3-tert-Butyl-6-(4-fluoro-benzenesu...) Show SMILES CC(C)(C)C1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C24H27FN2O4S/c1-24(2,3)15-4-10-21-19(12-15)20-13-17(7-11-22(20)27(21)14-23(28)29)26-32(30,31)18-8-5-16(25)6-9-18/h5-9,11,13,15,26H,4,10,12,14H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162901 (CHEMBL180733 | [5-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C19H17FN2O4S/c20-12-4-7-14(8-5-12)27(25,26)21-13-6-9-18-16(10-13)15-2-1-3-17(15)22(18)11-19(23)24/h4-10,21H,1-3,11H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26990 (CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...) Show SMILES [SH-] Show InChI InChI=1S/H2S/h1H2/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-1 by [18O]-exchange mass spectroscopy				Bioorg Med Chem Lett 25: 4937-40 (2015) Article DOI: 10.1016/j.bmcl.2015.05.001 BindingDB Entry DOI: 10.7270/Q2VQ34GP
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162925 (3-[6-(2-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3F)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-17-6-2-4-8-20(17)29(27,28)23-14-9-10-19-16(13-14)15-5-1-3-7-18(15)24(19)12-11-21(25)26/h2,4,6,8-10,13,23H,1,3,5,7,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Carbonic anhydrase, alpha family (Thiomicrospira crunogena (strain XCL-2))	BDBM26990 (CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...) Show SMILES [SH-] Show InChI InChI=1S/H2S/h1H2/p-1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of Thiomicrospira crunogena XCL-2 alpha-carbonic anhydrase expressed in Escherichia coli BL21 (DE3) cells by [18O]-exchange mass spectrosc...				Bioorg Med Chem Lett 25: 4937-40 (2015) Article DOI: 10.1016/j.bmcl.2015.05.001 BindingDB Entry DOI: 10.7270/Q2VQ34GP
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162902 (3-(6-Benzenesulfonylamino-1,2,3,4-tetrahydro-carba...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C21H22N2O4S/c24-21(25)12-13-23-19-9-5-4-8-17(19)18-14-15(10-11-20(18)23)22-28(26,27)16-6-2-1-3-7-16/h1-3,6-7,10-11,14,22H,4-5,8-9,12-13H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162892 (3-[6-(3-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3cccc(F)c3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-4-3-5-16(12-14)29(27,28)23-15-8-9-20-18(13-15)17-6-1-2-7-19(17)24(20)11-10-21(25)26/h3-5,8-9,12-13,23H,1-2,6-7,10-11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 in hTP binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162906 (3-[6-(3-Chloro-4-fluoro-benzenesulfonylamino)-1,2,...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)c(Cl)c3)ccc12 Show InChI InChI=1S/C21H20ClFN2O4S/c22-17-12-14(6-7-18(17)23)30(28,29)24-13-5-8-20-16(11-13)15-3-1-2-4-19(15)25(20)10-9-21(26)27/h5-8,11-12,24H,1-4,9-10H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162918 (3-[6-(4-Methoxy-benzenesulfonylamino)-1,2,3,4-tetr...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2n(CCC(O)=O)c3CCCCc3c2c1 Show InChI InChI=1S/C22H24N2O5S/c1-29-16-7-9-17(10-8-16)30(27,28)23-15-6-11-21-19(14-15)18-4-2-3-5-20(18)24(21)13-12-22(25)26/h6-11,14,23H,2-5,12-13H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162898 (2-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OS(=O)(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C20H21FN2O5S2/c21-14-5-8-16(9-6-14)30(27,28)22-15-7-10-20-18(13-15)17-3-1-2-4-19(17)23(20)11-12-29(24,25)26/h5-10,13,22H,1-4,11-12H2,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26990 (CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...) Show SMILES [SH-] Show InChI InChI=1S/H2S/h1H2/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2 by [18O]-exchange mass spectroscopy				Bioorg Med Chem Lett 25: 4937-40 (2015) Article DOI: 10.1016/j.bmcl.2015.05.001 BindingDB Entry DOI: 10.7270/Q2VQ34GP
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162926 (3-[6-(4-Chloro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C21H21ClN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162899 (3-[6-(Toluene-4-sulfonylamino)-1,2,3,4-tetrahydro-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2n(CCC(O)=O)c3CCCCc3c2c1 Show InChI InChI=1S/C22H24N2O4S/c1-15-6-9-17(10-7-15)29(27,28)23-16-8-11-21-19(14-16)18-4-2-3-5-20(18)24(21)13-12-22(25)26/h6-11,14,23H,2-5,12-13H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162924 (3-[6-(Biphenyl-4-sulfonylamino)-1,2,3,4-tetrahydro...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)ccc12 Show InChI InChI=1S/C27H26N2O4S/c30-27(31)16-17-29-25-9-5-4-8-23(25)24-18-21(12-15-26(24)29)28-34(32,33)22-13-10-20(11-14-22)19-6-2-1-3-7-19/h1-3,6-7,10-15,18,28H,4-5,8-9,16-17H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162919 (3-[6-(2,4-Difluoro-benzenesulfonylamino)-1,2,3,4-t...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3F)ccc12 Show InChI InChI=1S/C21H20F2N2O4S/c22-13-5-8-20(17(23)11-13)30(28,29)24-14-6-7-19-16(12-14)15-3-1-2-4-18(15)25(19)10-9-21(26)27/h5-8,11-12,24H,1-4,9-10H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162911 (3-[6-(3,4-Difluoro-benzenesulfonylamino)-1,2,3,4-t...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)c(F)c3)ccc12 Show InChI InChI=1S/C21H20F2N2O4S/c22-17-7-6-14(12-18(17)23)30(28,29)24-13-5-8-20-16(11-13)15-3-1-2-4-19(15)25(20)10-9-21(26)27/h5-8,11-12,24H,1-4,9-10H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162928 (3-[6-(Toluene-3-sulfonylamino)-1,2,3,4-tetrahydro-...) Show SMILES Cc1cccc(c1)S(=O)(=O)Nc1ccc2n(CCC(O)=O)c3CCCCc3c2c1 Show InChI InChI=1S/C22H24N2O4S/c1-15-5-4-6-17(13-15)29(27,28)23-16-9-10-21-19(14-16)18-7-2-3-8-20(18)24(21)12-11-22(25)26/h4-6,9-10,13-14,23H,2-3,7-8,11-12H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162929 (2-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES CC(C(O)=O)n1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c1-13(21(25)26)24-19-5-3-2-4-17(19)18-12-15(8-11-20(18)24)23-29(27,28)16-9-6-14(22)7-10-16/h6-13,23H,2-5H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162909 (5-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCCCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C23H25FN2O4S/c24-16-8-11-18(12-9-16)31(29,30)25-17-10-13-22-20(15-17)19-5-1-2-6-21(19)26(22)14-4-3-7-23(27)28/h8-13,15,25H,1-7,14H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162900 (4-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)c1ccc(cc1)-n1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN2O4S/c26-17-7-12-20(13-8-17)33(31,32)27-18-9-14-24-22(15-18)21-3-1-2-4-23(21)28(24)19-10-5-16(6-11-19)25(29)30/h5-15,27H,1-4H2,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162923 (3-[6-(Naphthalene-2-sulfonylamino)-1,2,3,4-tetrahy...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc4ccccc4c3)ccc12 Show InChI InChI=1S/C25H24N2O4S/c28-25(29)13-14-27-23-8-4-3-7-21(23)22-16-19(10-12-24(22)27)26-32(30,31)20-11-9-17-5-1-2-6-18(17)15-20/h1-2,5-6,9-12,15-16,26H,3-4,7-8,13-14H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162893 (3-[6-(4-Hydroxy-benzenesulfonylamino)-1,2,3,4-tetr...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(O)cc3)ccc12 Show InChI InChI=1S/C21H22N2O5S/c24-15-6-8-16(9-7-15)29(27,28)22-14-5-10-20-18(13-14)17-3-1-2-4-19(17)23(20)12-11-21(25)26/h5-10,13,22,24H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162916 (3-[6-(4-Phenoxy-benzenesulfonylamino)-1,2,3,4-tetr...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(Oc4ccccc4)cc3)ccc12 Show InChI InChI=1S/C27H26N2O5S/c30-27(31)16-17-29-25-9-5-4-8-23(25)24-18-19(10-15-26(24)29)28-35(32,33)22-13-11-21(12-14-22)34-20-6-2-1-3-7-20/h1-3,6-7,10-15,18,28H,4-5,8-9,16-17H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162905 (3-[6-(Thiophene-2-sulfonylamino)-1,2,3,4-tetrahydr...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3cccs3)ccc12 Show InChI InChI=1S/C19H20N2O4S2/c22-18(23)9-10-21-16-5-2-1-4-14(16)15-12-13(7-8-17(15)21)20-27(24,25)19-6-3-11-26-19/h3,6-8,11-12,20H,1-2,4-5,9-10H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162913 (4-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C22H23FN2O4S/c23-15-7-10-17(11-8-15)30(28,29)24-16-9-12-21-19(14-16)18-4-1-2-5-20(18)25(21)13-3-6-22(26)27/h7-12,14,24H,1-6,13H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair

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