Compile Data Set for Download or QSAR

Found 41 hits with Last Name = 'tutt' and Initial = 'mf'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297592 (1-(cyclopropylmethyl)-5-(methylsulfonyl)-2-neopent...) Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C16H27N3O2S/c1-16(2,3)9-15-17-13-11-18(22(4,20)21)8-7-14(13)19(15)10-12-5-6-12/h12H,5-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	439	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354863 (CHEMBL1834544) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2ccc(O)c(Cl)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H35ClF2O7S/c1-32-10-9-20(40)11-24(32)26(37)13-23-22-14-30-35(29(43)16-39,33(22,2)15-28(42)34(23,32)38)45-31(44-30)19-5-3-18(4-6-19)17-46-21-7-8-27(41)25(36)12-21/h3-12,22-23,26,28,30-31,39,41-42H,13-17H2,1-2H3/t22-,23-,26-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.97	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297594 (1-(cyclopropylmethyl)-5-(2-methoxyethylsulfonyl)-2...) Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C18H31N3O3S/c1-18(2,3)11-17-19-15-13-20(25(22,23)10-9-24-4)8-7-16(15)21(17)12-14-5-6-14/h14H,5-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21.5	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297595 (2-tert-butyl-1-(cyclopropylmethyl)-5-(2-methoxyeth...) Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C17H29N3O3S/c1-17(2,3)16-18-14-12-19(24(21,22)10-9-23-4)8-7-15(14)20(16)11-13-5-6-13/h13H,5-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26.7	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297596 (5-(benzylsulfonyl)-1-(cyclopropylmethyl)-2-neopent...) Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C22H31N3O2S/c1-22(2,3)13-21-23-19-15-24(12-11-20(19)25(21)14-17-9-10-17)28(26,27)16-18-7-5-4-6-8-18/h4-8,17H,9-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	13.4	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297597 (4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...) Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H28N4O3S/c1-12-17(13(2)26-21-12)27(24,25)22-9-8-16-15(11-22)20-18(19(3,4)5)23(16)10-14-6-7-14/h14H,6-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297598 (1-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...) Show SMILES CCCCC(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C20H33N3O/c1-5-6-7-19(24)22-11-10-17-16(14-22)21-18(12-20(2,3)4)23(17)13-15-8-9-15/h15H,5-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297599 (CHEMBL562149 | N-benzyl-2-tert-butyl-1-(cyclopropy...) Show SMILES CN(Cc1ccccc1)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C23H32N4O/c1-23(2,3)21-24-19-16-26(13-12-20(19)27(21)15-18-10-11-18)22(28)25(4)14-17-8-6-5-7-9-17/h5-9,18H,10-16H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	637	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297600 (CHEMBL564065 | N-benzyl-1-(cyclopropylmethyl)-N-me...) Show SMILES CN(Cc1ccccc1)C(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C24H34N4O/c1-24(2,3)14-22-25-20-17-27(13-12-21(20)28(22)16-19-10-11-19)23(29)26(4)15-18-8-6-5-7-9-18/h5-9,19H,10-17H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	523	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297601 (1-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...) Show SMILES CC(C)(C)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H31N3O/c1-18(2,3)16-20-14-12-21(17(23)19(4,5)6)10-9-15(14)22(16)11-13-7-8-13/h13H,7-12H2,1-6H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297602 (5-(benzylsulfonyl)-2-tert-butyl-1-(cyclopropylmeth...) Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C21H29N3O2S/c1-21(2,3)20-22-18-14-23(12-11-19(18)24(20)13-16-9-10-16)27(25,26)15-17-7-5-4-6-8-17/h4-8,16H,9-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21.8	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297603 (1-(cyclopropylmethyl)-2-neopentyl-5-(pyridin-3-yls...) Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C20H28N4O2S/c1-20(2,3)11-19-22-17-14-23(27(25,26)16-5-4-9-21-12-16)10-8-18(17)24(19)13-15-6-7-15/h4-5,9,12,15H,6-8,10-11,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24.5	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297604 (2-tert-butyl-1-(cyclopropylmethyl)-5-(pyridin-3-yl...) Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C19H26N4O2S/c1-19(2,3)18-21-16-13-22(26(24,25)15-5-4-9-20-11-15)10-8-17(16)23(18)12-14-6-7-14/h4-5,9,11,14H,6-8,10,12-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14.2	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297605 (1-(cyclopropylmethyl)-2-neopentyl-5-(phenylsulfony...) Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H29N3O2S/c1-21(2,3)13-20-22-18-15-23(27(25,26)17-7-5-4-6-8-17)12-11-19(18)24(20)14-16-9-10-16/h4-8,16H,9-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.10	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297606 (2-tert-butyl-1-(cyclopropylmethyl)-5-(phenylsulfon...) Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H27N3O2S/c1-20(2,3)19-21-17-14-22(26(24,25)16-7-5-4-6-8-16)12-11-18(17)23(19)13-15-9-10-15/h4-8,15H,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297607 (4-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...) Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C19H28N4O3S/c1-13-17(12-26-21-13)27(24,25)22-8-7-16-15(11-22)20-18(9-19(2,3)4)23(16)10-14-5-6-14/h12,14H,5-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18.5	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297608 (4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...) Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C18H26N4O3S/c1-12-16(11-25-20-12)26(23,24)21-8-7-15-14(10-21)19-17(18(2,3)4)22(15)9-13-5-6-13/h11,13H,5-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55.4	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297609 (4-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...) Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C20H30N4O3S/c1-13-19(14(2)27-22-13)28(25,26)23-9-8-17-16(12-23)21-18(10-20(3,4)5)24(17)11-15-6-7-15/h15H,6-12H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297610 (2-tert-butyl-1-(cyclopropylmethyl)-N-methyl-N-prop...) Show SMILES CCCN(C)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H32N4O/c1-6-10-21(5)18(24)22-11-9-16-15(13-22)20-17(19(2,3)4)23(16)12-14-7-8-14/h14H,6-13H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297611 (2-tert-butyl-1-(cyclopropylmethyl)-5-pentyl-4,5,6,...) Show SMILES CCCCCN1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H33N3/c1-5-6-7-11-21-12-10-17-16(14-21)20-18(19(2,3)4)22(17)13-15-8-9-15/h15H,5-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	878	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297612 (1-(cyclopropylmethyl)-2-neopentyl-5-pentyl-4,5,6,7...) Show SMILES CCCCCN1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C20H35N3/c1-5-6-7-11-22-12-10-18-17(15-22)21-19(13-20(2,3)4)23(18)14-16-8-9-16/h16H,5-15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297613 (CHEMBL561890 | propyl 1-(cyclopropylmethyl)-2-neop...) Show SMILES CCCOC(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C19H31N3O2/c1-5-10-24-18(23)21-9-8-16-15(13-21)20-17(11-19(2,3)4)22(16)12-14-6-7-14/h14H,5-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297614 (5-((5-bromo-2-methoxypyridin-3-yl)methyl)-2-tert-b...) Show SMILES COc1ncc(Br)cc1CN1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C21H29BrN4O/c1-21(2,3)20-24-17-13-25(8-7-18(17)26(20)11-14-5-6-14)12-15-9-16(22)10-23-19(15)27-4/h9-10,14H,5-8,11-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	295	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50297597 (4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...) Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C19H28N4O3S/c1-12-17(13(2)26-21-12)27(24,25)22-9-8-16-15(11-22)20-18(19(3,4)5)23(16)10-14-6-7-14/h14H,6-11H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50297608 (4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...) Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C Show InChI InChI=1S/C18H26N4O3S/c1-12-16(11-25-20-12)26(23,24)21-8-7-15-14(10-21)19-17(18(2,3)4)22(15)9-13-5-6-13/h11,13H,5-10H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50297594 (1-(cyclopropylmethyl)-5-(2-methoxyethylsulfonyl)-2...) Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1 Show InChI InChI=1S/C18H31N3O3S/c1-18(2,3)11-17-19-15-13-20(25(22,23)10-9-24-4)8-7-16(15)21(17)12-14-5-6-14/h14H,5-13H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354849 (CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...) Show SMILES CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF |r,c:18,t:14| Show InChI InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	1.09	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354850 (BUDESONIDE | US10869929, Compound Budesonide | US1...) Show SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:15,t:11| Show InChI InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	12.4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354851 (FLUTICASONE FUROATE | Veramyst) Show SMILES C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)SCF |r,c:12,t:8| Show InChI InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354852 (CHEMBL1834533) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccccc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O6/c1-32-13-12-23(39)15-26(32)27(36)16-25-24-17-30-35(29(41)19-38,33(24,2)18-28(40)34(25,32)37)43-31(42-30)22-10-8-21(9-11-22)14-20-6-4-3-5-7-20/h3-13,15,24-25,27-28,30-31,38,40H,14,16-19H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.780	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354853 (CHEMBL1834534) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccccc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C34H34F2O7/c1-31-13-12-20(38)14-25(31)26(35)15-24-23-16-29-34(28(40)18-37,32(23,2)17-27(39)33(24,31)36)43-30(42-29)19-8-10-22(11-9-19)41-21-6-4-3-5-7-21/h3-14,23-24,26-27,29-30,37,39H,15-18H2,1-2H3/t23-,24-,26-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354854 (CHEMBL1834535) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(cc1)-c1ccccc1 |r,c:15,t:11| Show InChI InChI=1S/C34H34F2O6/c1-31-13-12-22(38)14-25(31)26(35)15-24-23-16-29-34(28(40)18-37,32(23,2)17-27(39)33(24,31)36)42-30(41-29)21-10-8-20(9-11-21)19-6-4-3-5-7-19/h3-14,23-24,26-27,29-30,37,39H,15-18H2,1-2H3/t23-,24-,26-,27-,29+,30+,31-,32-,33-,34+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.78	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354855 (CHEMBL1834536) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CN2CCOCC2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C33H39F2NO7/c1-30-8-7-21(38)13-24(30)25(34)14-23-22-15-28-33(27(40)18-37,31(22,2)16-26(39)32(23,30)35)43-29(42-28)20-5-3-19(4-6-20)17-36-9-11-41-12-10-36/h3-8,13,22-23,25-26,28-29,37,39H,9-12,14-18H2,1-2H3/t22-,23-,25-,26-,28+,29+,30-,31-,32-,33+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.710	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354856 (CHEMBL1834537) Show SMILES CSc1cccc(Sc2ccc(cc2)[C@@H]2O[C@@H]3C[C@H]4[C@@H]5C[C@H](F)C6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@]4(C)[C@@]3(O2)C(=O)CO)c1 |r,c:28,t:24| Show InChI InChI=1S/C35H36F2O6S2/c1-32-12-11-20(39)13-26(32)27(36)15-25-24-16-30-35(29(41)18-38,33(24,2)17-28(40)34(25,32)37)43-31(42-30)19-7-9-21(10-8-19)45-23-6-4-5-22(14-23)44-3/h4-14,24-25,27-28,30-31,38,40H,15-18H2,1-3H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.93	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354857 (CHEMBL1834538) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)cc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O7/c1-32-12-11-23(40)14-26(32)27(36)15-25-24-16-30-35(29(42)18-38,33(24,2)17-28(41)34(25,32)37)44-31(43-30)21-7-3-19(4-8-21)13-20-5-9-22(39)10-6-20/h3-12,14,24-25,27-28,30-31,38-39,41H,13,15-18H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354858 (CHEMBL1834539) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Oc2ccc(=O)[nH]n2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C32H32F2N2O8/c1-29-10-9-17(38)11-21(29)22(33)12-20-19-13-25-32(24(40)15-37,30(19,2)14-23(39)31(20,29)34)44-28(43-25)16-3-5-18(6-4-16)42-27-8-7-26(41)35-36-27/h3-11,19-20,22-23,25,28,37,39H,12-15H2,1-2H3,(H,35,41)/t19-,20-,22-,23-,25+,28+,29-,30-,31-,32+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21.1	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354859 (CHEMBL1834540) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(SCc2ccccc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O6S/c1-32-13-12-22(39)14-26(32)27(36)15-25-24-16-30-35(29(41)18-38,33(24,2)17-28(40)34(25,32)37)43-31(42-30)21-8-10-23(11-9-21)44-19-20-6-4-3-5-7-20/h3-14,24-25,27-28,30-31,38,40H,15-19H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.35	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354860 (CHEMBL1834541) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2ccccc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O6S/c1-32-13-12-22(39)14-26(32)27(36)15-25-24-16-30-35(29(41)18-38,33(24,2)17-28(40)34(25,32)37)43-31(42-30)21-10-8-20(9-11-21)19-44-23-6-4-3-5-7-23/h3-14,24-25,27-28,30-31,38,40H,15-19H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.75	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354861 (CHEMBL1834542) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2ccc(O)cc2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O7S/c1-32-12-11-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-38,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-5-3-19(4-6-20)18-45-23-9-7-21(39)8-10-23/h3-13,24-25,27-28,30-31,38-39,41H,14-18H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.87	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50354862 (CHEMBL1834543) Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(CSc2cccc(O)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H36F2O7S/c1-32-11-10-22(40)13-26(32)27(36)14-25-24-15-30-35(29(42)17-38,33(24,2)16-28(41)34(25,32)37)44-31(43-30)20-8-6-19(7-9-20)18-45-23-5-3-4-21(39)12-23/h3-13,24-25,27-28,30-31,38-39,41H,14-18H2,1-2H3/t24-,25-,27-,28-,30+,31+,32-,33-,34-,35+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.82	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity				Bioorg Med Chem Lett 21: 5826-30 (2011) Article DOI: 10.1016/j.bmcl.2011.07.106 BindingDB Entry DOI: 10.7270/Q22V2GH4
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50297593 (2-tert-butyl-1-(cyclopropylmethyl)-5-(methylsulfon...) Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C15H25N3O2S/c1-15(2,3)14-16-12-10-17(21(4,19)20)8-7-13(12)18(14)9-11-5-6-11/h11H,5-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	403	n/a	n/a	n/a	n/a
Pfizer Discovery Chemistry Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release				Bioorg Med Chem Lett 19: 4406-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.062 BindingDB Entry DOI: 10.7270/Q28G8KRV
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