Compile Data Set for Download or QSAR

Found 106 hits with Last Name = 'varga' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359016 (CHEMBL1924017) Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1Oc1ccc(cc1)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C26H24Cl2F3N3O4S/c27-18-5-10-24(23(15-18)33-39(36,37)20-8-9-22(28)21(16-20)26(29,30)31)38-19-6-3-17(4-7-19)25(35)32-11-14-34-12-1-2-13-34/h3-10,15-16,33H,1-2,11-14H2,(H,32,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359013 (CHEMBL1924014) Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)cnc1Oc1ccc(cc1)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C26H25Cl2F3N4O4S/c27-18-14-23(34-40(37,38)20-8-9-22(28)21(15-20)26(29,30)31)25(33-16-18)39-19-6-4-17(5-7-19)24(36)32-10-13-35-11-2-1-3-12-35/h4-9,14-16,34H,1-3,10-13H2,(H,32,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359018 (CHEMBL1924019) Show SMILES COc1cc(Oc2ccc(cc2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)cc1Cl Show InChI InChI=1S/C27H26Cl2F3N3O5S/c1-39-24-16-25(40-18-6-4-17(5-7-18)26(36)33-10-13-35-11-2-3-12-35)23(15-22(24)29)34-41(37,38)19-8-9-21(28)20(14-19)27(30,31)32/h4-9,14-16,34H,2-3,10-13H2,1H3,(H,33,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359032 (CHEMBL1924024) Show SMILES COc1cc(ccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C27H26Cl2F3N3O5S/c1-39-25-14-17(26(36)33-10-13-35-11-2-3-12-35)4-8-24(25)40-23-9-5-18(28)15-22(23)34-41(37,38)19-6-7-21(29)20(16-19)27(30,31)32/h4-9,14-16,34H,2-3,10-13H2,1H3,(H,33,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359022 (CHEMBL1924023) Show SMILES Cc1cc(ccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C27H26Cl2F3N3O4S/c1-17-14-18(26(36)33-10-13-35-11-2-3-12-35)4-8-24(17)39-25-9-5-19(28)15-23(25)34-40(37,38)20-6-7-22(29)21(16-20)27(30,31)32/h4-9,14-16,34H,2-3,10-13H2,1H3,(H,33,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359017 (CHEMBL1924018) Show SMILES Cc1cc(Oc2ccc(cc2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)cc1Cl Show InChI InChI=1S/C27H26Cl2F3N3O4S/c1-17-14-25(39-19-6-4-18(5-7-19)26(36)33-10-13-35-11-2-3-12-35)24(16-23(17)29)34-40(37,38)20-8-9-22(28)21(15-20)27(30,31)32/h4-9,14-16,34H,2-3,10-13H2,1H3,(H,33,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359012 (CHEMBL1924013) Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1Oc1ccc(cc1)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C27H26Cl2F3N3O4S/c28-19-6-11-25(24(16-19)34-40(37,38)21-9-10-23(29)22(17-21)27(30,31)32)39-20-7-4-18(5-8-20)26(36)33-12-15-35-13-2-1-3-14-35/h4-11,16-17,34H,1-3,12-15H2,(H,33,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359023 (CHEMBL1170725) Show SMILES Cc1ncccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H12Cl3N3O3S/c1-10-16(3-2-6-21-10)26-17-15(7-11(18)9-22-17)23-27(24,25)12-4-5-13(19)14(20)8-12/h2-9,23H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359015 (CHEMBL1924016) Show SMILES COc1cc(Oc2ccc(cc2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)cc1Cl Show InChI InChI=1S/C28H28Cl2F3N3O5S/c1-40-25-17-26(41-19-7-5-18(6-8-19)27(37)34-11-14-36-12-3-2-4-13-36)24(16-23(25)30)35-42(38,39)20-9-10-22(29)21(15-20)28(31,32)33/h5-10,15-17,35H,2-4,11-14H2,1H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359025 (CHEMBL1924005) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-17-13-22(30-36(33,34)19-7-8-20(26)21(27)14-19)24(29-15-17)35-18-5-3-16(4-6-18)23(32)28-9-12-31-10-1-2-11-31/h3-8,13-15,30H,1-2,9-12H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359024 (CHEMBL1924004) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-18-14-23(31-37(34,35)20-8-9-21(27)22(28)15-20)25(30-16-18)36-19-6-4-17(5-7-19)24(33)29-10-13-32-11-2-1-3-12-32/h4-9,14-16,31H,1-3,10-13H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162903 (CHEMBL359855 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES CC1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C21H21FN2O4S/c1-13-2-8-19-17(10-13)18-11-15(5-9-20(18)24(19)12-21(25)26)23-29(27,28)16-6-3-14(22)4-7-16/h3-7,9,11,13,23H,2,8,10,12H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359014 (CHEMBL1924015) Show SMILES Cc1cc(Oc2ccc(cc2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)cc1Cl Show InChI InChI=1S/C28H28Cl2F3N3O4S/c1-18-15-26(40-20-7-5-19(6-8-20)27(37)34-11-14-36-12-3-2-4-13-36)25(17-24(18)30)35-41(38,39)21-9-10-23(29)22(16-21)28(31,32)33/h5-10,15-17,35H,2-4,11-14H2,1H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 in hTP binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359024 (CHEMBL1924004) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-18-14-23(31-37(34,35)20-8-9-21(27)22(28)15-20)25(30-16-18)36-19-6-4-17(5-7-19)24(33)29-10-13-32-11-2-1-3-12-32/h4-9,14-16,31H,1-3,10-13H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162894 (CHEMBL361972 | [2-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)CN1C2CCCCCC2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H23FN2O4S/c22-14-6-9-16(10-7-14)29(27,28)23-15-8-11-20-18(12-15)17-4-2-1-3-5-19(17)24(20)13-21(25)26/h6-12,17,19,23H,1-5,13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359021 (CHEMBL1924022) Show SMILES COc1cc(ccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C28H28Cl2F3N3O5S/c1-40-26-15-18(27(37)34-11-14-36-12-3-2-4-13-36)5-9-25(26)41-24-10-6-19(29)16-23(24)35-42(38,39)20-7-8-22(30)21(17-20)28(31,32)33/h5-10,15-17,35H,2-4,11-14H2,1H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359020 (CHEMBL1924021) Show SMILES Cc1cc(ccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C28H28Cl2F3N3O4S/c1-18-15-19(27(37)34-11-14-36-12-3-2-4-13-36)5-9-25(18)40-26-10-6-20(29)16-24(26)35-41(38,39)21-7-8-23(30)22(17-21)28(31,32)33/h5-10,15-17,35H,2-4,11-14H2,1H3,(H,34,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162917 (CHEMBL360288 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C20H19FN2O4S/c21-13-5-8-15(9-6-13)28(26,27)22-14-7-10-19-17(11-14)16-3-1-2-4-18(16)23(19)12-20(24)25/h5-11,22H,1-4,12H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359026 (CHEMBL1924006) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCNCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H24Cl3N5O4S/c25-17-13-22(31-37(34,35)19-5-6-20(26)21(27)14-19)24(30-15-17)36-18-3-1-16(2-4-18)23(33)29-9-12-32-10-7-28-8-11-32/h1-6,13-15,28,31H,7-12H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162891 (CHEMBL179980 | [6-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCC(Cc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12)c1ccccc1 Show InChI InChI=1S/C26H23FN2O4S/c27-19-7-10-21(11-8-19)34(32,33)28-20-9-13-25-23(15-20)22-14-18(17-4-2-1-3-5-17)6-12-24(22)29(25)16-26(30)31/h1-5,7-11,13,15,18,28H,6,12,14,16H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359025 (CHEMBL1924005) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-17-13-22(30-36(33,34)19-7-8-20(26)21(27)14-19)24(29-15-17)35-18-5-3-16(4-6-18)23(32)28-9-12-31-10-1-2-11-31/h3-8,13-15,30H,1-2,9-12H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359019 (CHEMBL1924020) Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)Nc1cc(Cl)ccc1Oc1ccc(cc1)C(=O)NCCN1CCC(F)(F)C1 Show InChI InChI=1S/C26H22Cl2F5N3O4S/c27-17-3-8-23(22(13-17)35-41(38,39)19-6-7-21(28)20(14-19)26(31,32)33)40-18-4-1-16(2-5-18)24(37)34-10-12-36-11-9-25(29,30)15-36/h1-8,13-14,35H,9-12,15H2,(H,34,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359033 (CHEMBL1924012) Show SMILES Clc1ccc(Oc2ccc(cc2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C26H26Cl3N3O4S/c27-19-6-11-25(24(16-19)31-37(34,35)21-9-10-22(28)23(29)17-21)36-20-7-4-18(5-8-20)26(33)30-12-15-32-13-2-1-3-14-32/h4-11,16-17,31H,1-3,12-15H2,(H,30,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359027 (CHEMBL1924007) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-18-14-23(31-37(34,35)20-7-8-21(27)22(28)15-20)25(30-16-18)36-19-6-4-5-17(13-19)24(33)29-9-12-32-10-2-1-3-11-32/h4-8,13-16,31H,1-3,9-12H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359028 (CHEMBL1924008) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-17-13-22(30-36(33,34)19-6-7-20(26)21(27)14-19)24(29-15-17)35-18-5-3-4-16(12-18)23(32)28-8-11-31-9-1-2-10-31/h3-7,12-15,30H,1-2,8-11H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162896 (CHEMBL369330 | [3-tert-Butyl-6-(4-fluoro-benzenesu...) Show SMILES CC(C)(C)C1CCc2c(C1)c1cc(NS(=O)(=O)c3ccc(F)cc3)ccc1n2CC(O)=O Show InChI InChI=1S/C24H27FN2O4S/c1-24(2,3)15-4-10-21-19(12-15)20-13-17(7-11-22(20)27(21)14-23(28)29)26-32(30,31)18-8-5-16(25)6-9-18/h5-9,11,13,15,26H,4,10,12,14H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359029 (CHEMBL1924009) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCNCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H24Cl3N5O4S/c25-17-13-22(31-37(34,35)19-4-5-20(26)21(27)14-19)24(30-15-17)36-18-3-1-2-16(12-18)23(33)29-8-11-32-9-6-28-7-10-32/h1-5,12-15,28,31H,6-11H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162901 (CHEMBL180733 | [5-(4-Fluoro-benzenesulfonylamino)-...) Show SMILES OC(=O)Cn1c2CCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C19H17FN2O4S/c20-12-4-7-14(8-5-12)27(25,26)21-13-6-9-18-16(10-13)15-2-1-3-17(15)22(18)11-19(23)24/h4-10,21H,1-3,11H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359026 (CHEMBL1924006) Show SMILES Clc1cnc(Oc2ccc(cc2)C(=O)NCCN2CCNCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H24Cl3N5O4S/c25-17-13-22(31-37(34,35)19-5-6-20(26)21(27)14-19)24(30-15-17)36-18-3-1-16(2-4-18)23(33)29-9-12-32-10-7-28-8-11-32/h1-6,13-15,28,31H,7-12H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50161746 ((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CC[C@H](Cc2c2ccccc12)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calcium				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359031 (CHEMBL1924011) Show SMILES Clc1cnc(Oc2ccccc2C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-16-13-21(30-36(33,34)17-7-8-19(26)20(27)14-17)24(29-15-16)35-22-6-2-1-5-18(22)23(32)28-9-12-31-10-3-4-11-31/h1-2,5-8,13-15,30H,3-4,9-12H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359030 (CHEMBL1924010) Show SMILES Clc1cnc(Oc2ccccc2C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-17-14-22(31-37(34,35)18-8-9-20(27)21(28)15-18)25(30-16-17)36-23-7-3-2-6-19(23)24(33)29-10-13-32-11-4-1-5-12-32/h2-3,6-9,14-16,31H,1,4-5,10-13H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162925 (3-[6-(2-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3F)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-17-6-2-4-8-20(17)29(27,28)23-14-9-10-19-16(13-14)15-5-1-3-7-18(15)24(19)12-11-21(25)26/h2,4,6,8-10,13,23H,1,3,5,7,11-12H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359028 (CHEMBL1924008) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-17-13-22(30-36(33,34)19-6-7-20(26)21(27)14-19)24(29-15-17)35-18-5-3-4-16(12-18)23(32)28-8-11-31-9-1-2-10-31/h3-7,12-15,30H,1-2,8-11H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162902 (3-(6-Benzenesulfonylamino-1,2,3,4-tetrahydro-carba...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C21H22N2O4S/c24-21(25)12-13-23-19-9-5-4-8-17(19)18-14-15(10-11-20(18)23)22-28(26,27)16-6-2-1-3-7-16/h1-3,6-7,10-11,14,22H,4-5,8-9,12-13H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359027 (CHEMBL1924007) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-18-14-23(31-37(34,35)20-7-8-21(27)22(28)15-20)25(30-16-18)36-19-6-4-5-17(13-19)24(33)29-9-12-32-10-2-1-3-11-32/h4-8,13-16,31H,1-3,9-12H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359023 (CHEMBL1170725) Show SMILES Cc1ncccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H12Cl3N3O3S/c1-10-16(3-2-6-21-10)26-17-15(7-11(18)9-22-17)23-27(24,25)12-4-5-13(19)14(20)8-12/h2-9,23H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162892 (3-[6-(3-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3cccc(F)c3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-4-3-5-16(12-14)29(27,28)23-15-8-9-20-18(13-15)17-6-1-2-7-19(17)24(20)11-10-21(25)26/h3-5,8-9,12-13,23H,1-2,6-7,10-11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50162897 (3-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h5-10,13,23H,1-4,11-12H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 in hTP binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359030 (CHEMBL1924010) Show SMILES Clc1cnc(Oc2ccccc2C(=O)NCCN2CCCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C25H25Cl3N4O4S/c26-17-14-22(31-37(34,35)18-8-9-20(27)21(28)15-18)25(30-16-17)36-23-7-3-2-6-19(23)24(33)29-10-13-32-11-4-1-5-12-32/h2-3,6-9,14-16,31H,1,4-5,10-13H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162906 (3-[6-(3-Chloro-4-fluoro-benzenesulfonylamino)-1,2,...) Show SMILES OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)c(Cl)c3)ccc12 Show InChI InChI=1S/C21H20ClFN2O4S/c22-17-12-14(6-7-18(17)23)30(28,29)24-13-5-8-20-16(11-13)15-3-1-2-4-19(15)25(20)10-9-21(26)27/h5-8,11-12,24H,1-4,9-10H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162918 (3-[6-(4-Methoxy-benzenesulfonylamino)-1,2,3,4-tetr...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2n(CCC(O)=O)c3CCCCc3c2c1 Show InChI InChI=1S/C22H24N2O5S/c1-29-16-7-9-17(10-8-16)30(27,28)23-15-6-11-21-19(14-15)18-4-2-3-5-20(18)24(21)13-12-22(25)26/h6-11,14,23H,2-5,12-13H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50162898 (2-[6-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetra...) Show SMILES OS(=O)(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc12 Show InChI InChI=1S/C20H21FN2O5S2/c21-14-5-8-16(9-6-14)30(27,28)22-15-7-10-20-18(13-15)17-3-1-2-4-19(17)23(20)11-12-29(24,25)26/h5-10,13,22H,1-4,11-12H2,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes				Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359029 (CHEMBL1924009) Show SMILES Clc1cnc(Oc2cccc(c2)C(=O)NCCN2CCNCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H24Cl3N5O4S/c25-17-13-22(31-37(34,35)19-4-5-20(26)21(27)14-19)24(30-15-17)36-18-3-1-2-16(12-18)23(33)29-8-11-32-9-6-28-7-10-32/h1-5,12-15,28,31H,6-11H2,(H,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359031 (CHEMBL1924011) Show SMILES Clc1cnc(Oc2ccccc2C(=O)NCCN2CCCC2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C24H23Cl3N4O4S/c25-16-13-21(30-36(33,34)17-7-8-19(26)20(27)14-17)24(29-15-16)35-22-6-2-1-5-18(22)23(32)28-9-12-31-10-3-4-11-31/h1-2,5-8,13-15,30H,3-4,9-12H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...				Bioorg Med Chem Lett 21: 7291-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.038 BindingDB Entry DOI: 10.7270/Q2KK9C6D
					More data for this Ligand-Target Pair

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