Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Translocator protein (Rattus norvegicus (rat)) | BDBM150169 (US8980887, Compound 13) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.97 | -49.5 | 6.99 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150168 (US8980887, Compound 11) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.66 | -47.5 | 15.6 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150164 (US8980887, Compound 1) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 7.17 | -47.3 | 16.9 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150166 (US8980887, Compound 8) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 9.34 | -46.6 | 21.9 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150167 (US8980887, Compound 10) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 11.1 | -46.2 | 26.1 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150170 (US8980887, Compound 14) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 38.7 | -43.0 | 91.0 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM150165 (US8980887, Compound 7) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 49.2 | -42.4 | 116 | n/a | n/a | n/a | n/a | n/a | 30 |
Institute of Pharmacology; Toxicology Academy of Military Medical Sciences P.L.A., China US Patent | Assay Description Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(... | US Patent US8980887 (2015) BindingDB Entry DOI: 10.7270/Q2D50KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50321104 (CHEMBL1163804 | DFGYVAE) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of the Chemistry of Plant Substances Curated by ChEMBL | Assay Description Competitive inhibition of HMG-CoA reductase by Dixon plot analysis | Bioorg Med Chem 18: 4300-9 (2010) Article DOI: 10.1016/j.bmc.2010.04.090 BindingDB Entry DOI: 10.7270/Q2VM4CFG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50321100 (CHEMBL1164546 | GF(4-fluro)PTGG) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of the Chemistry of Plant Substances Curated by ChEMBL | Assay Description Competitive inhibition of HMG-CoA reductase by Dixon plot analysis | Bioorg Med Chem 18: 4300-9 (2010) Article DOI: 10.1016/j.bmc.2010.04.090 BindingDB Entry DOI: 10.7270/Q2VM4CFG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50004566 (9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatum | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50023492 (5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatum | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310205 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310235 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50023492 (5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50067593 (CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Institute of Biotechnology Curated by ChEMBL | Assay Description Inhibition of HIV1 recombinant protease | Eur J Med Chem 45: 4096-103 (2010) Article DOI: 10.1016/j.ejmech.2010.05.070 BindingDB Entry DOI: 10.7270/Q2C53PP4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310214 (2-(3-Bromophenyl)-7-(3'-cyclopropylmethoxy-4'-difl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM16034 (1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Institute of Pharmacology and Toxicology Curated by ChEMBL | Assay Description Inhibition of recombinant human BACE1 proteolytic activity | Bioorg Med Chem Lett 22: 1408-14 (2012) Article DOI: 10.1016/j.bmcl.2011.12.034 BindingDB Entry DOI: 10.7270/Q24Q7VGC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50220373 (2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOL...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CrystalGenomics, Inc. Curated by ChEMBL | Assay Description Inhibition of GSK3beta at 5 uM | Bioorg Med Chem Lett 17: 5686-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.056 BindingDB Entry DOI: 10.7270/Q2HH6JT3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM16034 (1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Institute of Pharmacology and Toxicology Curated by ChEMBL | Assay Description Inhibition of BACE1 | Bioorg Med Chem Lett 22: 1408-14 (2012) Article DOI: 10.1016/j.bmcl.2011.12.034 BindingDB Entry DOI: 10.7270/Q24Q7VGC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310226 (Acetic acid 3-[7-(3'-cyclopropylmethoxy-4'-difluor...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50023505 (2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatum | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM16034 (1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Institute of Pharmacology and Toxicology Curated by ChEMBL | Assay Description Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assay | Bioorg Med Chem Lett 22: 1408-14 (2012) Article DOI: 10.1016/j.bmcl.2011.12.034 BindingDB Entry DOI: 10.7270/Q24Q7VGC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310210 (7-(3'-Cyclopentyloxy-4'-methoxyphenyl)-2-(3-chloro...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310225 (3-(7-(3-(cyclopropylmethoxy)-4-methoxyphenyl)pyraz...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50004566 (9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50023495 (2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50023500 ((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310240 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50220369 (CHEMBL399140 | N-(4-(methylsulfonamido)phenethyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
CrystalGenomics, Inc. Curated by ChEMBL | Assay Description Inhibition of GSK3beta at 5 uM | Bioorg Med Chem Lett 17: 5686-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.056 BindingDB Entry DOI: 10.7270/Q2HH6JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310244 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50023496 (2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatum | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310204 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310238 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM16034 (1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Institute of Pharmacology and Toxicology Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site by sAPP_NF cell based assay | Bioorg Med Chem Lett 22: 1408-14 (2012) Article DOI: 10.1016/j.bmcl.2011.12.034 BindingDB Entry DOI: 10.7270/Q24Q7VGC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310245 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310213 (7-(3'-Cyclopentyloxy-4'-methoxyphenyl)-2-(2,5-dich...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310215 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310211 (2-(3-Bromophenyl)-7-(3'-cyclopentyloxy-4'-methoxyp...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50023505 (2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310246 (5-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310223 (2-(3-(allyloxy)phenyl)-7-(3-(cyclopropylmethoxy)-4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310229 (CHEMBL603230 | N-{3-[7-(3'-Cyclopropylmethoxy-4'-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310220 (2-(3-Chlorophenyl)-7-(3'-cyclopropylmethoxy-4'-dif...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310216 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50023496 (2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description Inhibition of binding towards adenosine A1 receptor using [3H]-N-cyclohexyladenosine ([3H]-CHA) in rat whole brain membranes. | J Med Chem 31: 1014-20 (1988) BindingDB Entry DOI: 10.7270/Q2T43S4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310241 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310212 (7-(3'-Cyclopentyloxy-4'-methoxyphenyl)-2-(3-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310228 (CHEMBL598049 | {3-[7-(3'-Cyclopropylmethoxy-4'-dif...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310230 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50310236 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S | |||||||||||
More data for this Ligand-Target Pair |
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