Found 23 hits Enz. Inhib. hit(s) with all data for entry = 50028006 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256003
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H10BrN5O2S/c14-5-3-22-10-6-4(7-12(21)19-13(15)18-7)1-2-16-11(20)9(6)17-8(5)10/h3,17H,1-2H2,(H,16,20)(H3,15,18,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256004
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(csc3c12)C#N |w:3.2,t:1| Show InChI InChI=1S/C14H10N6O2S/c15-3-5-4-23-11-7-6(9-13(22)20-14(16)19-9)1-2-17-12(21)10(7)18-8(5)11/h4,18H,1-2H2,(H,17,21)(H3,16,19,20,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256043
((Z)-3-bromohymenialdisine | CHEMBL480350 | Hymenia...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c(Br)c(Br)c12 |w:3.2,t:1| Show InChI InChI=1S/C11H9Br2N5O2/c12-5-4-3(6-10(20)18-11(14)17-6)1-2-15-9(19)7(4)16-8(5)13/h16H,1-2H2,(H,15,19)(H3,14,17,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256000
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Cl)csc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H10ClN5O2S/c14-5-3-22-10-6-4(7-12(21)19-13(15)18-7)1-2-16-11(20)9(6)17-8(5)10/h3,17H,1-2H2,(H,16,20)(H3,15,18,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256047
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3ccsc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H11N5O2S/c14-13-17-8(12(20)18-13)5-1-3-15-11(19)9-7(5)10-6(16-9)2-4-21-10/h2,4,16H,1,3H2,(H,15,19)(H3,14,17,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256025
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC(=O)c1csc2c3c([nH]c12)C(=O)NCCC3=C1N=C(N)NC1=O |w:17.20,t:21| Show InChI InChI=1S/C14H12N6O3S/c15-11(21)5-3-24-10-6-4(8-13(23)20-14(16)19-8)1-2-17-12(22)9(6)18-7(5)10/h3,18H,1-2H2,(H2,15,21)(H,17,22)(H3,16,19,20,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256028
(4-[2-Amino-4-oxo-4H-thiazol-(5)-ylidene]-4,6,7,9-t...)Show SMILES NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3ccsc3c12 |w:5.5,t:1| Show InChI InChI=1S/C13H10N4O2S2/c14-13-17-12(19)9(21-13)5-1-3-15-11(18)8-7(5)10-6(16-8)2-4-20-10/h2,4,16H,1,3H2,(H,15,18)(H2,14,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256029
(4-[2-Amino-4-oxo-4H-thiazol-(5)-ylidene]-1-bromo-4...)Show SMILES NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12 |w:5.5,t:1| Show InChI InChI=1S/C13H9BrN4O2S2/c14-5-3-21-10-6-4(9-12(20)18-13(15)22-9)1-2-16-11(19)8(6)17-7(5)10/h3,17H,1-2H2,(H,16,19)(H2,15,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256027
(10-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c4ccccc4sc3c12 |w:3.2,t:1| Show InChI InChI=1S/C17H13N5O2S/c18-17-21-12(16(24)22-17)8-5-6-19-15(23)13-10(8)14-11(20-13)7-3-1-2-4-9(7)25-14/h1-4,20H,5-6H2,(H,19,23)(H3,18,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256008
(CHEMBL517241 | {5-[1-Bromo-8-oxo-6,7,8,9-tetrahydr...)Show SMILES OC(=O)CNC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12 |w:7.7,t:5| Show InChI InChI=1S/C15H12BrN5O4S/c16-6-4-26-12-8-5(1-2-17-13(24)11(8)19-10(6)12)9-14(25)21-15(20-9)18-3-7(22)23/h4,19H,1-3H2,(H,17,24)(H,22,23)(H2,18,20,21,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256030
(1-Bromo-4-[2-(2-hydroxy-ethylamino)-5-oxo-3,5-dihy...)Show SMILES OCCNC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12 |w:6.5,t:4| Show InChI InChI=1S/C15H14BrN5O3S/c16-7-5-25-12-8-6(1-2-17-13(23)11(8)19-10(7)12)9-14(24)21-15(20-9)18-3-4-22/h5,19,22H,1-4H2,(H,17,23)(H2,18,20,21,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256048
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3cc(Cl)sc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H10ClN5O2S/c14-6-3-5-10(22-6)7-4(8-12(21)19-13(15)18-8)1-2-16-11(20)9(7)17-5/h3,17H,1-2H2,(H,16,20)(H3,15,18,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM16591
((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)Show SMILES NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]ccc12 |w:7.18,t:1| Show InChI InChI=1S/C11H11N5O2/c12-11-15-8(10(18)16-11)6-2-4-14-9(17)7-5(6)1-3-13-7/h1,3,13H,2,4H2,(H,14,17)(H3,12,15,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256002
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3cc(Br)sc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H10BrN5O2S/c14-6-3-5-10(22-6)7-4(8-12(21)19-13(15)18-8)1-2-16-11(20)9(7)17-5/h3,17H,1-2H2,(H,16,20)(H3,15,18,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50025098
(CHEMBL332551)Show SMILES Nc1nc(c(O)[nH]1)C1=C2C(=Nc3ccccc23)C(=O)NCC1 |c:10,t:8| Show InChI InChI=1S/C15H13N5O2/c16-15-19-11(14(22)20-15)8-5-6-17-13(21)12-10(8)7-3-1-2-4-9(7)18-12/h1-4,22H,5-6H2,(H,17,21)(H3,16,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256001
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Cl)c(Cl)sc3c12 |w:3.2,t:1| Show InChI InChI=1S/C13H9Cl2N5O2S/c14-5-8-9(23-10(5)15)4-3(6-12(22)20-13(16)19-6)1-2-17-11(21)7(4)18-8/h18H,1-2H2,(H,17,21)(H3,16,19,20,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256026
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(csc3c12)-c1ccccc1 |w:3.3,t:1| Show InChI InChI=1S/C19H15N5O2S/c20-19-23-14(18(26)24-19)10-6-7-21-17(25)15-12(10)16-13(22-15)11(8-27-16)9-4-2-1-3-5-9/h1-5,8,22H,6-7H2,(H,21,25)(H3,20,23,24,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256009
(4-[2-(2-Hydroxy-ethylamino)-5-oxo-3,5-dihydro-imid...)Show SMILES OCCNC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3ccsc3c12 |w:6.5,t:4| Show InChI InChI=1S/C15H15N5O3S/c21-5-4-17-15-19-10(14(23)20-15)7-1-3-16-13(22)11-9(7)12-8(18-11)2-6-24-12/h2,6,18,21H,1,3-5H2,(H,16,22)(H2,17,19,20,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM7491
((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)Show SMILES NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]c(Br)cc12 |w:7.19,t:1| Show InChI InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256006
(4-[2-Amino-4-oxo-4H-thiazol-(5)-ylidene]-1-phenyl-...)Show SMILES NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3c(csc3c12)-c1ccccc1 |w:5.4,t:1| Show InChI InChI=1S/C19H14N4O2S2/c20-19-23-18(25)15(27-19)10-6-7-21-17(24)14-12(10)16-13(22-14)11(8-26-16)9-4-2-1-3-5-9/h1-5,8,22H,6-7H2,(H,21,24)(H2,20,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256046
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES COc1ccc(Cn2c3c(C(CCNC3=O)=C3N=C(N)NC3=O)c3scc(Br)c23)cc1 |w:16.22,t:18| Show InChI InChI=1S/C21H18BrN5O3S/c1-30-11-4-2-10(3-5-11)8-27-16-13(22)9-31-18(16)14-12(6-7-24-20(29)17(14)27)15-19(28)26-21(23)25-15/h2-5,9H,6-8H2,1H3,(H,24,29)(H3,23,25,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256045
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)Show SMILES Cn1c2c(C(CCNC2=O)=C2N=C(N)NC2=O)c2sccc12 |w:10.11,t:12| Show InChI InChI=1S/C14H13N5O2S/c1-19-7-3-5-22-11(7)8-6(2-4-16-13(21)10(8)19)9-12(20)18-14(15)17-9/h3,5H,2,4H2,1H3,(H,16,21)(H3,15,17,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50256007
(10-[2-Amino-4-oxo-4H-thiazol-(5)-ylidene]-7,8,9,10...)Show SMILES NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3c4ccccc4sc3c12 |w:5.5,t:1| Show InChI InChI=1S/C17H12N4O2S2/c18-17-21-16(23)13(25-17)8-5-6-19-15(22)12-10(8)14-11(20-12)7-3-1-2-4-9(7)24-14/h1-4,20H,5-6H2,(H,19,22)(H2,18,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier
Curated by ChEMBL
| Assay Description Inhibition of CHK1 |
Bioorg Med Chem Lett 19: 841-4 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.001 BindingDB Entry DOI: 10.7270/Q2QN66MH |
More data for this Ligand-Target Pair | |