Found 87 hits Enz. Inhib. hit(s) with all data for entry = 50041788 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50172920
(3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(pip...)Show SMILES Clc1ccccc1Nc1ccc2c(n[nH]c2c1)-c1cccc(c1)C(=O)NC1CCNCC1 Show InChI InChI=1S/C25H24ClN5O/c26-21-6-1-2-7-22(21)28-19-8-9-20-23(15-19)30-31-24(20)16-4-3-5-17(14-16)25(32)29-18-10-12-27-13-11-18/h1-9,14-15,18,27-28H,10-13H2,(H,29,32)(H,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of JNK3 by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50172920
(3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(pip...)Show SMILES Clc1ccccc1Nc1ccc2c(n[nH]c2c1)-c1cccc(c1)C(=O)NC1CCNCC1 Show InChI InChI=1S/C25H24ClN5O/c26-21-6-1-2-7-22(21)28-19-8-9-20-23(15-19)30-31-24(20)16-4-3-5-17(14-16)25(32)29-18-10-12-27-13-11-18/h1-9,14-15,18,27-28H,10-13H2,(H,29,32)(H,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of p38alpha by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50178832
(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)Show SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1 Show InChI InChI=1S/C21H20N4O2/c26-21(17-8-11-27-14-17)25-20-13-16(7-10-23-20)15-6-9-22-19(12-15)24-18-4-2-1-3-5-18/h1-7,9-10,12-13,17H,8,11,14H2,(H,22,24)(H,23,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of JNK3 by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal histidine-tagged human full length JNK3 by radiometric filter binding assay |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50172920
(3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-N-(pip...)Show SMILES Clc1ccccc1Nc1ccc2c(n[nH]c2c1)-c1cccc(c1)C(=O)NC1CCNCC1 Show InChI InChI=1S/C25H24ClN5O/c26-21-6-1-2-7-22(21)28-19-8-9-20-23(15-19)30-31-24(20)16-4-3-5-17(14-16)25(32)29-18-10-12-27-13-11-18/h1-9,14-15,18,27-28H,10-13H2,(H,29,32)(H,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of JNK1 by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal histidine-tagged human full length JNK3 by radiometric filter binding assay |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50178832
(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)Show SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1 Show InChI InChI=1S/C21H20N4O2/c26-21(17-8-11-27-14-17)25-20-13-16(7-10-23-20)15-6-9-22-19(12-15)24-18-4-2-1-3-5-18/h1-7,9-10,12-13,17H,8,11,14H2,(H,22,24)(H,23,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of p38alpha by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415612
(CHEMBL1083185)Show InChI InChI=1S/C16H13BrClNO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| DrugBank MMDB PDB Article PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50178832
(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)Show SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1 Show InChI InChI=1S/C21H20N4O2/c26-21(17-8-11-27-14-17)25-20-13-16(7-10-23-20)15-6-9-22-19(12-15)24-18-4-2-1-3-5-18/h1-7,9-10,12-13,17H,8,11,14H2,(H,22,24)(H,23,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of JNK1 by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415624
(CHEMBL1077129)Show InChI InChI=1S/C16H12Cl2FNO/c1-21-14-7-9-5-6-20-16(11(9)8-13(14)18)10-3-2-4-12(17)15(10)19/h2-4,7-8H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal histidine-tagged human full length JNK2-alpha-2 by radiometric filter binding assay |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415614
(CHEMBL1088053)Show InChI InChI=1S/C20H16ClNO/c1-23-19-11-15-8-9-22-20(17(15)12-18(19)21)16-7-6-13-4-2-3-5-14(13)10-16/h2-7,10-12H,8-9H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal histidine-tagged human full length JNK2-alpha-2 by radiometric filter binding assay |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415621
(CHEMBL1088634)Show InChI InChI=1S/C17H16ClNO/c1-11-4-3-5-13(8-11)17-14-10-15(18)16(20-2)9-12(14)6-7-19-17/h3-5,8-10H,6-7H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415606
(CHEMBL1084664)Show InChI InChI=1S/C16H13ClFNO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)17)11-3-2-4-12(18)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415608
(CHEMBL1082866)Show InChI InChI=1S/C16H13ClFNO/c1-20-15-8-11-6-7-19-16(13(11)9-14(15)17)10-2-4-12(18)5-3-10/h2-5,8-9H,6-7H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415618
(CHEMBL1077132)Show InChI InChI=1S/C16H14ClNO/c1-19-15-9-12-7-8-18-16(13(12)10-14(15)17)11-5-3-2-4-6-11/h2-6,9-10H,7-8H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415610
(CHEMBL1086653)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1OC |t:7| Show InChI InChI=1S/C17H15Cl2NO2/c1-21-15-8-10-5-6-20-17(12(10)9-16(15)22-2)11-3-4-13(18)14(19)7-11/h3-4,7-9H,5-6H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415613
(CHEMBL1077137)Show InChI InChI=1S/C16H13BrClNO/c1-20-15-9-13-10(8-14(15)18)5-6-19-16(13)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of B-Raf |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of c-Fms |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of EGFR |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of GSK3-beta |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of IKKalpha |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50415625
(CHEMBL1077118)Show InChI InChI=1S/C17H16ClNO2/c1-20-15-9-11-6-7-19-17(14(11)10-16(15)21-2)12-4-3-5-13(18)8-12/h3-5,8-10H,6-7H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of JNK3 by high throughput screening |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of LCK |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of MLK3 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of PLK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Rho-associated protein kinase 1
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of ROCK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of SGK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of B-Raf |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of c-Fms |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of CDK2 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of EGFR |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of ErbB2 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of GSK3-beta |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of IKKalpha |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of MLK3 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Rho-associated protein kinase 1
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of ROCK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of CDK2 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of ErbB2 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human)) | BDBM50415616
(CHEMBL1087421)Show SMILES COc1cc2CCN=C(c3ccc(Cl)c(Cl)c3)c2cc1Cl |t:7| Show InChI InChI=1S/C16H12Cl3NO/c1-21-15-7-9-4-5-20-16(11(9)8-14(15)19)10-2-3-12(17)13(18)6-10/h2-3,6-8H,4-5H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of IKK-beta |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of IKK-beta |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of PLK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of SGK1 |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50415620
(CHEMBL1088633)Show InChI InChI=1S/C16H13Cl2NO/c1-20-15-8-10-5-6-19-16(13(10)9-14(15)18)11-3-2-4-12(17)7-11/h2-4,7-9H,5-6H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D
Curated by ChEMBL
| Assay Description Inhibition of LCK |
Bioorg Med Chem Lett 19: 2230-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR |
More data for this Ligand-Target Pair | |