Compile Data Set for Download or QSAR

Found 102 hits Enz. Inhib. hit(s) with all data for entry = 50010225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PDGFRalpha				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FLT1				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human RET				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human EGFR T790M mutant				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human IGF1R				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human EPHA2				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Ephrin type-B receptor 2 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human EPHB2				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human c-Kit				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human ABL				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human EGFR				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human RON				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human ERBB4				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human ALK				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human AXL				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FGFR1				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human c- SRC				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536471 (CHEMBL4532610) Show SMILES CC(NC\N=C\c1ccccc1)c1ccc2ncccc2c1 Show InChI InChI=1S/C19H19N3/c1-15(22-14-20-13-16-6-3-2-4-7-16)17-9-10-19-18(12-17)8-5-11-21-19/h2-13,15,22H,14H2,1H3/b20-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536472 (CHEMBL4581168) Show SMILES C[C@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536473 (CHEMBL4570217) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1 |r| Show InChI InChI=1S/C23H16F2N6O/c1-12(16-7-13-3-2-6-27-19(13)9-18(16)25)31-11-29-22-23(31)30-20(10-28-22)14-4-5-15(21(26)32)17(24)8-14/h2-12H,1H3,(H2,26,32)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536474 (CHEMBL4536783) Show SMILES CC(c1cc2cccnc2cc1C)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C26H20N6/c1-16-10-23-19(7-5-9-27-23)12-21(16)17(2)32-15-30-25-26(32)31-24(14-29-25)20-11-18-6-3-4-8-22(18)28-13-20/h3-15,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536475 (CHEMBL4522638) Show SMILES C(c1ccc2ncccc2c1)n1cnc2ncc(nc12)-c1ccccc1 Show InChI InChI=1S/C21H15N5/c1-2-5-16(6-3-1)19-12-23-20-21(25-19)26(14-24-20)13-15-8-9-18-17(11-15)7-4-10-22-18/h1-12,14H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536476 (CHEMBL4549233) Show SMILES CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H17N7/c1-12-15(5-6-17-16(12)4-3-7-21-17)13(2)27-11-23-19-20(27)26-18(10-22-19)14-8-24-25-9-14/h3-11,13H,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536477 (CHEMBL4585798) Show SMILES CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1ccncc1 Show InChI InChI=1S/C21H14F2N6/c1-12(18-15(22)9-16-14(19(18)23)3-2-6-25-16)29-11-27-20-21(29)28-17(10-26-20)13-4-7-24-8-5-13/h2-12H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536478 (CHEMBL4554813) Show SMILES COC(=O)c1ccc(cc1F)-c1cnc2ncn(C(C)c3c(F)cc4ncccc4c3F)c2n1 Show InChI InChI=1S/C24H16F3N5O2/c1-12(20-17(26)9-18-15(21(20)27)4-3-7-28-18)32-11-30-22-23(32)31-19(10-29-22)13-5-6-14(16(25)8-13)24(33)34-2/h3-12H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536480 (CHEMBL4568802) Show SMILES CC(c1cc2cccnc2cc1C)n1cnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1 Show InChI InChI=1S/C24H19FN6O/c1-13-8-20-15(4-3-7-27-20)9-18(13)14(2)31-12-29-23-24(31)30-21(11-28-23)16-5-6-17(22(26)32)19(25)10-16/h3-12,14H,1-2H3,(H2,26,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536481 (CHEMBL4566100) Show SMILES CC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C25H17FN6/c1-15(19-10-17-6-4-8-27-22(17)11-20(19)26)32-14-30-24-25(32)31-23(13-29-24)18-9-16-5-2-3-7-21(16)28-12-18/h2-15H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536482 (CHEMBL4519755) Show SMILES CCC(c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C26H19FN6/c1-2-24(19-11-17-7-5-9-28-22(17)12-20(19)27)33-15-31-25-26(33)32-23(14-30-25)18-10-16-6-3-4-8-21(16)29-13-18/h3-15,24H,2H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536483 (CHEMBL4524262) Show SMILES CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C25H16F2N6/c1-14(22-18(26)10-20-17(23(22)27)6-4-8-28-20)33-13-31-24-25(33)32-21(12-30-24)16-9-15-5-2-3-7-19(15)29-11-16/h2-14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536484 (CHEMBL4540942) Show SMILES CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C26H20N6/c1-16-20(9-10-23-21(16)7-5-11-27-23)17(2)32-15-30-25-26(32)31-24(14-29-25)19-12-18-6-3-4-8-22(18)28-13-19/h3-15,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50396934 (CHEMBL2001019 | CHEMBL2170804 | US9062045, Compara...) Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536485 (CHEMBL4519339) Show SMILES Cn1cc(cn1)-c1cnc2nc(O)n(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-14(8-22-25)16-9-21-17-18(23-16)26(19(27)24-17)10-12-4-5-15-13(7-12)3-2-6-20-15/h2-9,11H,10H2,1H3,(H,21,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536486 (CHEMBL4559256) Show SMILES Oc1nc2ncc(nc2n1Cc1ccc2ncccc2c1)-c1ccccc1 Show InChI InChI=1S/C21H15N5O/c27-21-25-19-20(24-18(12-23-19)15-5-2-1-3-6-15)26(21)13-14-8-9-17-16(11-14)7-4-10-22-17/h1-12H,13H2,(H,23,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536487 (CHEMBL4557414) Show SMILES Oc1nc2ncc(nc2n1Cc1ccc2ncccc2c1)-c1ccncc1 Show InChI InChI=1S/C20H14N6O/c27-20-25-18-19(24-17(11-23-18)14-5-8-21-9-6-14)26(20)12-13-3-4-16-15(10-13)2-1-7-22-16/h1-11H,12H2,(H,23,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536488 (CHEMBL4556499) Show SMILES C(c1ccc2ncccc2c1)n1cnc2ncc(nc12)-c1cn[nH]c1 Show InChI InChI=1S/C18H13N7/c1-2-13-6-12(3-4-15(13)19-5-1)10-25-11-21-17-18(25)24-16(9-20-17)14-7-22-23-8-14/h1-9,11H,10H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536489 (CHEMBL4541026) Show SMILES OCCn1cc(cn1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C20H17N7O/c28-7-6-27-12-16(9-24-27)18-10-22-19-20(25-18)26(13-23-19)11-14-3-4-17-15(8-14)2-1-5-21-17/h1-5,8-10,12-13,28H,6-7,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536490 (CHEMBL4565038) Show SMILES CN(C)c1cccc(c1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C23H20N6/c1-28(2)19-7-3-5-18(12-19)21-13-25-22-23(27-21)29(15-26-22)14-16-8-9-20-17(11-16)6-4-10-24-20/h3-13,15H,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536491 (CHEMBL4554402) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C22H14F3N5O/c23-22(24,25)31-17-6-4-15(5-7-17)19-11-27-20-21(29-19)30(13-28-20)12-14-3-8-18-16(10-14)2-1-9-26-18/h1-11,13H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536492 (CHEMBL4551055) Show SMILES Fc1ccccc1-c1cnc2ncn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C21H14FN5/c22-17-6-2-1-5-16(17)19-11-24-20-21(26-19)27(13-25-20)12-14-7-8-18-15(10-14)4-3-9-23-18/h1-11,13H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536493 (CHEMBL4558786) Show SMILES CC(NC\N=C\c1cnn(C)c1)c1ccc2ncccc2c1 Show InChI InChI=1S/C17H19N5/c1-13(20-12-18-9-14-10-21-22(2)11-14)15-5-6-17-16(8-15)4-3-7-19-17/h3-11,13,20H,12H2,1-2H3/b18-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536494 (CHEMBL4564491) Show SMILES CC(NC\N=C\c1ccnn1C)c1ccc2ncccc2c1 Show InChI InChI=1S/C17H19N5/c1-13(20-12-18-11-16-7-9-21-22(16)2)14-5-6-17-15(10-14)4-3-8-19-17/h3-11,13,20H,12H2,1-2H3/b18-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536495 (CHEMBL4567631) Show SMILES CC(NC\N=C\c1cn[nH]c1)c1ccc2ncccc2c1 Show InChI InChI=1S/C16H17N5/c1-12(19-11-17-8-13-9-20-21-10-13)14-4-5-16-15(7-14)3-2-6-18-16/h2-10,12,19H,11H2,1H3,(H,20,21)/b17-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536496 (CHEMBL4541607) Show SMILES COC(=O)c1ccc(\C=N\CNC(C)c2ccc3ncccc3c2)cc1F Show InChI InChI=1S/C21H20FN3O2/c1-14(16-6-8-20-17(11-16)4-3-9-24-20)25-13-23-12-15-5-7-18(19(22)10-15)21(26)27-2/h3-12,14,25H,13H2,1-2H3/b23-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536497 (CHEMBL4560881) Show SMILES CNC(=O)c1ccc(\C=N\CNC(C)c2ccc3ncccc3c2)cc1F Show InChI InChI=1S/C21H21FN4O/c1-14(16-6-8-20-17(11-16)4-3-9-25-20)26-13-24-12-15-5-7-18(19(22)10-15)21(27)23-2/h3-12,14,26H,13H2,1-2H3,(H,23,27)/b24-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536498 (CHEMBL4591638) Show SMILES CC(c1cc(F)c2ncccc2c1)n1cnc2ncc(nc12)-c1cccc2ccccc12 Show InChI InChI=1S/C26H18FN5/c1-16(19-12-18-8-5-11-28-24(18)22(27)13-19)32-15-30-25-26(32)31-23(14-29-25)21-10-4-7-17-6-2-3-9-20(17)21/h2-16H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536499 (CHEMBL4524495) Show SMILES CC(c1c(F)cc2ncccc2c1F)n1cnc2ncc(nc12)-c1cccc2ccccc12 Show InChI InChI=1S/C26H17F2N5/c1-15(23-20(27)12-21-19(24(23)28)10-5-11-29-21)33-14-31-25-26(33)32-22(13-30-25)18-9-4-7-16-6-2-3-8-17(16)18/h2-15H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536500 (CHEMBL4483635) Show SMILES CC(c1cc(F)c2ncccc2c1)n1cnc2ncc(nc12)-c1cnn(C)c1 Show InChI InChI=1S/C20H16FN7/c1-12(14-6-13-4-3-5-22-18(13)16(21)7-14)28-11-24-19-20(28)26-17(9-23-19)15-8-25-27(2)10-15/h3-12H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536479 (CHEMBL4068255) Show SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C20H16FN7/c1-12(15-6-13-4-3-5-22-17(13)7-16(15)21)28-11-24-19-20(28)26-18(9-23-19)14-8-25-27(2)10-14/h3-12H,1-2H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536501 (CHEMBL4548105) Show SMILES CCC(c1ccc2ncccc2c1F)n1cnc2ncc(nc12)-c1cnn(C)c1 Show InChI InChI=1S/C21H18FN7/c1-3-18(15-6-7-16-14(19(15)22)5-4-8-23-16)29-12-25-20-21(29)27-17(10-24-20)13-9-26-28(2)11-13/h4-12,18H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019 BindingDB Entry DOI: 10.7270/Q2PN9949
					More data for this Ligand-Target Pair

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