Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with all data for entry = 3211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM29388 (Exanta | Melagatran | US11584714, Compound 999) Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)[C@H](NCC(O)=O)C2CCCCC2)cc1 Show InChI InChI=1S/C22H31N5O4/c23-20(24)16-8-6-14(7-9-16)12-26-21(30)17-10-11-27(17)22(31)19(25-13-18(28)29)15-4-2-1-3-5-15/h6-9,15,17,19,25H,1-5,10-13H2,(H3,23,24)(H,26,30)(H,28,29)/t17-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description The thrombin inhibitor potency (IC50) was measured with a chromogenic substrate method in a robotic microplate processor, using 96-well, half-volume ...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prothrombin (Homo sapiens (Human))	BDBM29379 (proline scaffold, 28) Show SMILES N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C25H27N3O2S/c26-23(22(18-9-3-1-4-10-18)19-11-5-2-6-12-19)25(30)28-15-7-14-21(28)24(29)27-17-20-13-8-16-31-20/h1-6,8-13,16,21-23H,7,14-15,17,26H2,(H,27,29)/t21-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	270	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29383 (proline scaffold, 32) Show SMILES N[C@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C18H27N3O2S/c19-16(13-6-2-1-3-7-13)18(23)21-10-4-9-15(21)17(22)20-12-14-8-5-11-24-14/h5,8,11,13,15-16H,1-4,6-7,9-10,12,19H2,(H,20,22)/t15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	1.10E+3	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29375 (proline scaffold, 24) Show SMILES N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C19H22ClN3O2S/c20-14-7-5-13(6-8-14)11-16(21)19(25)23-9-1-4-17(23)18(24)22-12-15-3-2-10-26-15/h2-3,5-8,10,16-17H,1,4,9,11-12,21H2,(H,22,24)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	2.20E+3	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29377 (proline scaffold, 26) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H29N3O2/c1-2-15-25-22(27)19-14-9-16-26(19)23(28)21(24)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-21H,2,9,14-16,24H2,1H3,(H,25,27)/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.80E+4	3.10E+3	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prothrombin (Homo sapiens (Human))	BDBM29385 (proline scaffold, 34) Show SMILES N[C@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCC1CCCCC1 |r| Show InChI InChI=1S/C20H35N3O2/c21-18(16-10-5-2-6-11-16)20(25)23-13-7-12-17(23)19(24)22-14-15-8-3-1-4-9-15/h15-18H,1-14,21H2,(H,22,24)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	9.00E+3	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29367 (proline scaffold, 16) Show SMILES OC1(CC(=O)N2CCC[C@H]2C(=O)NCc2cccs2)c2ccccc2-c2ccccc12 |r| Show InChI InChI=1S/C25H24N2O3S/c28-23(27-13-5-12-22(27)24(29)26-16-17-7-6-14-31-17)15-25(30)20-10-3-1-8-18(20)19-9-2-4-11-21(19)25/h1-4,6-11,14,22,30H,5,12-13,15-16H2,(H,26,29)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+4	2.30E+4	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29378 (proline scaffold, 27) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H29N3O3/c1-29-16-14-25-22(27)19-13-8-15-26(19)23(28)21(24)20(17-9-4-2-5-10-17)18-11-6-3-7-12-18/h2-7,9-12,19-21H,8,13-16,24H2,1H3,(H,25,27)/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+4	6.80E+3	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29381 (proline scaffold, 30) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C16H29N3O2/c1-2-10-18-15(20)13-9-6-11-19(13)16(21)14(17)12-7-4-3-5-8-12/h12-14H,2-11,17H2,1H3,(H,18,20)/t13-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	2.70E+4	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29359 (proline scaffold, 8) Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C25H26N2O2S/c28-24(17-22(19-9-3-1-4-10-19)20-11-5-2-6-12-20)27-15-7-14-23(27)25(29)26-18-21-13-8-16-30-21/h1-6,8-13,16,22-23H,7,14-15,17-18H2,(H,26,29)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	3.40E+4	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29386 (proline scaffold, 35) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)[C@H](NS(=O)(=O)Cc1ccccc1)C1CCCCC1 |r| Show InChI InChI=1S/C21H31N3O4S/c1-22-20(25)18-13-8-14-24(18)21(26)19(17-11-6-3-7-12-17)23-29(27,28)15-16-9-4-2-5-10-16/h2,4-5,9-10,17-19,23H,3,6-8,11-15H2,1H3,(H,22,25)/t18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+5	3.50E+4	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29373 (proline scaffold, 22) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H24ClN3O2/c1-2-9-20-16(22)15-4-3-10-21(15)17(23)14(19)11-12-5-7-13(18)8-6-12/h5-8,14-15H,2-4,9-11,19H2,1H3,(H,20,22)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+5	4.50E+4	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29376 (proline scaffold, 25) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H25N3O2/c1-23-20(25)17-13-8-14-24(17)21(26)19(22)18(15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17-19H,8,13-14,22H2,1H3,(H,23,25)/t17-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	3.80E+4	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29384 (proline scaffold, 33) Show SMILES CC(C)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C17H31N3O2/c1-12(2)11-19-16(21)14-9-6-10-20(14)17(22)15(18)13-7-4-3-5-8-13/h12-15H,3-11,18H2,1-2H3,(H,19,21)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	4.90E+4	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29365 (proline scaffold, 14) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)CC1(O)c2ccccc2-c2ccccc12 |r| Show InChI InChI=1S/C23H26N2O3/c1-2-13-24-22(27)20-12-7-14-25(20)21(26)15-23(28)18-10-5-3-8-16(18)17-9-4-6-11-19(17)23/h3-6,8-11,20,28H,2,7,12-15H2,1H3,(H,24,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+5	9.90E+4	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29371 (proline scaffold, 20) Show SMILES O=C(Cc1ccc2OCOc2c1)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C19H20N2O4S/c22-18(10-13-5-6-16-17(9-13)25-12-24-16)21-7-1-4-15(21)19(23)20-11-14-3-2-8-26-14/h2-3,5-6,8-9,15H,1,4,7,10-12H2,(H,20,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+5	2.50E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29372 (proline scaffold, 21) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-18-14(20)13-3-2-8-19(13)15(21)12(17)9-10-4-6-11(16)7-5-10/h4-7,12-13H,2-3,8-9,17H2,1H3,(H,18,20)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	5.50E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29374 (proline scaffold, 23) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H24ClN3O3/c1-24-10-8-20-16(22)15-3-2-9-21(15)17(23)14(19)11-12-4-6-13(18)7-5-12/h4-7,14-15H,2-3,8-11,19H2,1H3,(H,20,22)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	1.40E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29380 (proline scaffold, 29) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C14H25N3O2/c1-16-13(18)11-8-5-9-17(11)14(19)12(15)10-6-3-2-4-7-10/h10-12H,2-9,15H2,1H3,(H,16,18)/t11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	7.90E+5	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29382 (proline scaffold, 31) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1 |r| Show InChI InChI=1S/C16H29N3O3/c1-22-11-9-18-15(20)13-8-5-10-19(13)16(21)14(17)12-6-3-2-4-7-12/h12-14H,2-11,17H2,1H3,(H,18,20)/t13-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	1.10E+5	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29387 (proline scaffold, 36) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](O)C1CCCCC1 |r| Show InChI InChI=1S/C16H28N2O4/c1-22-11-9-17-15(20)13-8-5-10-18(13)16(21)14(19)12-6-3-2-4-7-12/h12-14,19H,2-11H2,1H3,(H,17,20)/t13-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	n/a	n/a
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29370 (proline scaffold, 19) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)Cc1ccc2OCOc2c1 |r| Show InChI InChI=1S/C17H22N2O5/c1-22-8-6-18-17(21)13-3-2-7-19(13)16(20)10-12-4-5-14-15(9-12)24-11-23-14/h4-5,9,13H,2-3,6-8,10-11H2,1H3,(H,18,21)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29369 (proline scaffold, 18) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)Cc1ccc2OCOc2c1 |r| Show InChI InChI=1S/C17H22N2O4/c1-2-7-18-17(21)13-4-3-8-19(13)16(20)10-12-5-6-14-15(9-12)23-11-22-14/h5-6,9,13H,2-4,7-8,10-11H2,1H3,(H,18,21)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29368 (proline scaffold, 17) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)Cc1ccc2OCOc2c1 |r| Show InChI InChI=1S/C15H18N2O4/c1-16-15(19)11-3-2-6-17(11)14(18)8-10-4-5-12-13(7-10)21-9-20-12/h4-5,7,11H,2-3,6,8-9H2,1H3,(H,16,19)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29366 (proline scaffold, 15) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)CC1(O)c2ccccc2-c2ccccc12 |r| Show InChI InChI=1S/C23H26N2O4/c1-29-14-12-24-22(27)20-11-6-13-25(20)21(26)15-23(28)18-9-4-2-7-16(18)17-8-3-5-10-19(17)23/h2-5,7-10,20,28H,6,11-15H2,1H3,(H,24,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	7.50E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29364 (proline scaffold, 13) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)CC1(O)c2ccccc2-c2ccccc12 |r| Show InChI InChI=1S/C21H22N2O3/c1-22-20(25)18-11-6-12-23(18)19(24)13-21(26)16-9-4-2-7-14(16)15-8-3-5-10-17(15)21/h2-5,7-10,18,26H,6,11-13H2,1H3,(H,22,25)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29363 (proline scaffold, 12) Show SMILES O=C(CC1CCCCC1)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C18H26N2O2S/c21-17(12-14-6-2-1-3-7-14)20-10-4-9-16(20)18(22)19-13-15-8-5-11-23-15/h5,8,11,14,16H,1-4,6-7,9-10,12-13H2,(H,19,22)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29362 (proline scaffold, 11) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)CC1CCCCC1 |r| Show InChI InChI=1S/C16H28N2O3/c1-21-11-9-17-16(20)14-8-5-10-18(14)15(19)12-13-6-3-2-4-7-13/h13-14H,2-12H2,1H3,(H,17,20)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29361 (proline scaffold, 10) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)CC1CCCCC1 |r| Show InChI InChI=1S/C16H28N2O2/c1-2-10-17-16(20)14-9-6-11-18(14)15(19)12-13-7-4-3-5-8-13/h13-14H,2-12H2,1H3,(H,17,20)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29360 (proline scaffold, 9) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)CC1CCCCC1 |r| Show InChI InChI=1S/C14H24N2O2/c1-15-14(18)12-8-5-9-16(12)13(17)10-11-6-3-2-4-7-11/h11-12H,2-10H2,1H3,(H,15,18)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29358 (proline scaffold, 7) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H28N2O3/c1-28-16-14-24-23(27)21-13-8-15-25(21)22(26)17-20(18-9-4-2-5-10-18)19-11-6-3-7-12-19/h2-7,9-12,20-21H,8,13-17H2,1H3,(H,24,27)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29357 (proline scaffold, 6) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H28N2O2/c1-2-15-24-23(27)21-14-9-16-25(21)22(26)17-20(18-10-5-3-6-11-18)19-12-7-4-8-13-19/h3-8,10-13,20-21H,2,9,14-17H2,1H3,(H,24,27)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	2.70E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29356 (proline scaffold, 5) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H24N2O2/c1-22-21(25)19-13-8-14-23(19)20(24)15-18(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-15H2,1H3,(H,22,25)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29355 (proline scaffold, 4) Show SMILES Clc1ccc(CCC(=O)N2CCC[C@H]2C(=O)NCc2cccs2)cc1 |r| Show InChI InChI=1S/C19H21ClN2O2S/c20-15-8-5-14(6-9-15)7-10-18(23)22-11-1-4-17(22)19(24)21-13-16-3-2-12-25-16/h2-3,5-6,8-9,12,17H,1,4,7,10-11,13H2,(H,21,24)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	7.00E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29354 (proline scaffold, 3) Show SMILES COCCNC(=O)[C@@H]1CCCN1C(=O)CCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H23ClN2O3/c1-23-12-10-19-17(22)15-3-2-11-20(15)16(21)9-6-13-4-7-14(18)8-5-13/h4-5,7-8,15H,2-3,6,9-12H2,1H3,(H,19,22)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	6.20E+5	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29352 (proline scaffold, 1) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)CCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H19ClN2O2/c1-17-15(20)13-3-2-10-18(13)14(19)9-6-11-4-7-12(16)8-5-11/h4-5,7-8,13H,2-3,6,9-10H2,1H3,(H,17,20)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM29353 (proline scaffold, 2) Show SMILES CCCNC(=O)[C@@H]1CCCN1C(=O)CCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H23ClN2O2/c1-2-11-19-17(22)15-4-3-12-20(15)16(21)10-7-13-5-8-14(18)9-6-13/h5-6,8-9,15H,2-4,7,10-12H2,1H3,(H,19,22)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair