Compile Data Set for Download or QSAR

Found 95 hits Enz. Inhib. hit(s) with all data for entry = 2353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362679 (US9840498, 5) Show SMILES Cn1cc(cn1)-c1c(F)ccc2nc([C@@H]3CCCN3c3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C27H22FN9O/c1-35-14-16(13-33-35)22-19(28)9-10-20-23(22)27(38)37(17-6-3-2-4-7-17)26(34-20)21-8-5-11-36(21)25-18(12-29)24(30)31-15-32-25/h2-4,6-7,9-10,13-15,21H,5,8,11H2,1H3,(H2,30,31,32)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362702 (US9840498, 29) Show SMILES CCOc1ncc(cn1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26FN9O3/c1-3-43-30-34-13-17(14-35-30)24-21(31)9-10-22-25(24)28(42)40(18-7-5-4-6-8-18)27(37-22)23-11-19(41)15-39(23)26-20(12-32)16(2)36-29(33)38-26/h4-10,13-14,19,23,41H,3,11,15H2,1-2H3,(H2,33,36,38)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362696 (US9840498, 22) Show SMILES COc1ncc(cn1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C29H25N9O3/c1-16-21(12-30)25(36-28(31)34-16)37-15-19(39)11-23(37)26-35-22-10-6-9-20(17-13-32-29(41-2)33-14-17)24(22)27(40)38(26)18-7-4-3-5-8-18/h3-10,13-14,19,23,39H,11,15H2,1-2H3,(H2,31,34,36)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362705 (US9840498, 32) Show SMILES CCOc1ncc(cn1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H27N9O2/c1-3-41-30-33-16-19(17-34-30)21-11-7-12-23-25(21)28(40)39(20-9-5-4-6-10-20)27(36-23)24-13-8-14-38(24)26-22(15-31)18(2)35-29(32)37-26/h4-7,9-12,16-17,24H,3,8,13-14H2,1-2H3,(H2,32,35,37)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362686 (US9840498, 12) Show SMILES CO[C@H]1C[C@H](N(C1)c1nc(N)nc(C)c1C#N)c1nc2cccc(-c3cnc(OC)nc3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C30H27N9O3/c1-17-22(13-31)26(37-29(32)35-17)38-16-20(41-2)12-24(38)27-36-23-11-7-10-21(18-14-33-30(42-3)34-15-18)25(23)28(40)39(27)19-8-5-4-6-9-19/h4-11,14-15,20,24H,12,16H2,1-3H3,(H2,32,35,37)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362697 (US9840498, 24) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O2/c1-17-22(14-30)26(35-29(31)33-17)36-16-20(38)13-24(36)27-34-23-11-5-10-21(18-7-6-12-32-15-18)25(23)28(39)37(27)19-8-3-2-4-9-19/h2-12,15,20,24,38H,13,16H2,1H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362684 (US9840498, 10) Show SMILES CO[C@H]1C[C@H](N(C1)c1nc(N)nc(C)c1C#N)c1nc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C29H27N9O2/c1-17-22(13-30)26(35-29(31)33-17)37-16-20(40-3)12-24(37)27-34-23-11-7-10-21(18-14-32-36(2)15-18)25(23)28(39)38(27)19-8-5-4-6-9-19/h4-11,14-15,20,24H,12,16H2,1-3H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362699 (US9840498, 26) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H23N9O2/c1-16-21(11-29)25(35-28(30)33-16)36-14-19(38)10-23(36)26-34-22-9-5-8-20(17-12-31-15-32-13-17)24(22)27(39)37(26)18-6-3-2-4-7-18/h2-9,12-13,15,19,23,38H,10,14H2,1H3,(H2,30,33,35)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362681 (US9840498, 7) Show SMILES COc1ncc(cn1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C29H24FN9O3/c1-15-19(11-31)25(37-28(32)35-15)38-14-18(40)10-22(38)26-36-21-9-8-20(30)23(16-12-33-29(42-2)34-13-16)24(21)27(41)39(26)17-6-4-3-5-7-17/h3-9,12-13,18,22,40H,10,14H2,1-2H3,(H2,32,35,37)/t18-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362678 (US9840498, 4) Show SMILES COc1ncc(cn1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C29H25N9O2/c1-17-21(14-30)25(36-28(31)34-17)37-13-7-12-23(37)26-35-22-11-6-10-20(18-15-32-29(40-2)33-16-18)24(22)27(39)38(26)19-8-4-3-5-9-19/h3-6,8-11,15-16,23H,7,12-13H2,1-2H3,(H2,31,34,36)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362687 (US9840498, 13) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H25N9O/c1-17-21(14-29)25(34-28(30)32-17)36-13-7-12-23(36)26-33-22-11-6-10-20(18-15-31-35(2)16-18)24(22)27(38)37(26)19-8-4-3-5-9-19/h3-6,8-11,15-16,23H,7,12-13H2,1-2H3,(H2,30,32,34)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362690 (US9840498, 16) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H25N9O2/c1-16-21(12-29)25(34-28(30)32-16)36-15-19(38)11-23(36)26-33-22-10-6-9-20(17-13-31-35(2)14-17)24(22)27(39)37(26)18-7-4-3-5-8-18/h3-10,13-14,19,23,38H,11,15H2,1-2H3,(H2,30,32,34)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362677 (US9840498, 3) Show SMILES COc1ncc(cn1)-c1cccc2nc([C@@H]3CCCN3c3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23N9O2/c1-39-28-31-14-17(15-32-28)19-9-5-10-21-23(19)27(38)37(18-7-3-2-4-8-18)26(35-21)22-11-6-12-36(22)25-20(13-29)24(30)33-16-34-25/h2-5,7-10,14-16,22H,6,11-12H2,1H3,(H2,30,33,34)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362675 (US9840498, 1) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N Show InChI InChI=1S/C28H24FN9O2/c1-15-19(11-30)25(35-28(31)33-15)37-14-18(39)10-22(37)26-34-21-9-8-20(29)23(16-12-32-36(2)13-16)24(21)27(40)38(26)17-6-4-3-5-7-17/h3-9,12-13,18,22,39H,10,14H2,1-2H3,(H2,31,33,35)/t18-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362680 (US9840498, 6) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-19(13-30)25(35-28(31)33-16)37-12-6-9-22(37)26-34-21-11-10-20(29)23(17-14-32-36(2)15-17)24(21)27(39)38(26)18-7-4-3-5-8-18/h3-5,7-8,10-11,14-15,22H,6,9,12H2,1-2H3,(H2,31,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362701 (US9840498, 28) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cnn(CCO)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H27N9O3/c1-17-22(13-30)26(35-29(31)33-17)37-16-20(40)12-24(37)27-34-23-9-5-8-21(18-14-32-36(15-18)10-11-39)25(23)28(41)38(27)19-6-3-2-4-7-19/h2-9,14-15,20,24,39-40H,10-12,16H2,1H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362700 (US9840498, 27) Show SMILES COc1ccc(cn1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-22(14-31)27(36-30(32)34-17)37-16-20(39)13-24(37)28-35-23-10-6-9-21(18-11-12-25(41-2)33-15-18)26(23)29(40)38(28)19-7-4-3-5-8-19/h3-12,15,20,24,39H,13,16H2,1-2H3,(H2,32,34,36)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362706 (US9840498, 33) Show SMILES Nc1ncnc(N2CCC[C@H]2c2nc3cccc(C#CCO)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C26H21N7O2/c27-15-19-23(28)29-16-30-24(19)32-13-5-12-21(32)25-31-20-11-4-7-17(8-6-14-34)22(20)26(35)33(25)18-9-2-1-3-10-18/h1-4,7,9-11,16,21,34H,5,12-14H2,(H2,28,29,30)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362704 (US9840498, 31) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3ccc(F)c(-c4cn(C)cn4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O2/c1-15-18(11-30)25(35-28(31)33-15)37-12-17(39)10-22(37)26-34-20-9-8-19(29)23(21-13-36(2)14-32-21)24(20)27(40)38(26)16-6-4-3-5-7-16/h3-9,13-14,17,22,39H,10,12H2,1-2H3,(H2,31,33,35)/t17-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362702 (US9840498, 29) Show SMILES CCOc1ncc(cn1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26FN9O3/c1-3-43-30-34-13-17(14-35-30)24-21(31)9-10-22-25(24)28(42)40(18-7-5-4-6-8-18)27(37-22)23-11-19(41)15-39(23)26-20(12-32)16(2)36-29(33)38-26/h4-10,13-14,19,23,41H,3,11,15H2,1-2H3,(H2,33,36,38)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362692 (US9840498, 18) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O2/c1-18-23(15-31)27(36-30(32)34-18)37-13-7-12-25(37)28-35-24-11-6-10-22(19-14-21(40-2)17-33-16-19)26(24)29(39)38(28)20-8-4-3-5-9-20/h3-6,8-11,14,16-17,25H,7,12-13H2,1-2H3,(H2,32,34,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362682 (US9840498, 8) Show SMILES Cn1cc(cn1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C27H22FN9O2/c1-35-12-15(11-33-35)22-19(28)7-8-20-23(22)27(39)37(16-5-3-2-4-6-16)26(34-20)21-9-17(38)13-36(21)25-18(10-29)24(30)31-14-32-25/h2-8,11-12,14,17,21,38H,9,13H2,1H3,(H2,30,31,32)/t17-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362703 (US9840498, 30) Show SMILES Cc1nc(N)nc(N2C[C@@H](F)C[C@H]2c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-21(12-30)25(35-28(31)33-16)37-15-18(29)11-23(37)26-34-22-10-6-9-20(17-13-32-36(2)14-17)24(22)27(39)38(26)19-7-4-3-5-8-19/h3-10,13-14,18,23H,11,15H2,1-2H3,(H2,31,33,35)/t18-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362694 (US9840498, 20) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O/c1-18-22(16-30)26(35-29(31)33-18)36-15-7-13-24(36)27-34-23-12-5-11-21(19-8-6-14-32-17-19)25(23)28(38)37(27)20-9-3-2-4-10-20/h2-6,8-12,14,17,24H,7,13,15H2,1H3,(H2,31,33,35)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362693 (US9840498, 19) Show SMILES Cc1ncc(cn1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C29H25N9O/c1-17-22(14-30)26(36-29(31)34-17)37-13-7-12-24(37)27-35-23-11-6-10-21(19-15-32-18(2)33-16-19)25(23)28(39)38(27)20-8-4-3-5-9-20/h3-6,8-11,15-16,24H,7,12-13H2,1-2H3,(H2,31,34,36)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362701 (US9840498, 28) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cnn(CCO)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H27N9O3/c1-17-22(13-30)26(35-29(31)33-17)37-16-20(40)12-24(37)27-34-23-9-5-8-21(18-14-32-36(15-18)10-11-39)25(23)28(41)38(27)19-6-3-2-4-7-19/h2-9,14-15,20,24,39-40H,10-12,16H2,1H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362691 (US9840498, 17) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H23N9O/c1-17-21(13-29)25(35-28(30)33-17)36-12-6-11-23(36)26-34-22-10-5-9-20(18-14-31-16-32-15-18)24(22)27(38)37(26)19-7-3-2-4-8-19/h2-5,7-10,14-16,23H,6,11-12H2,1H3,(H2,30,33,35)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362695 (US9840498, 21) Show SMILES COc1ccc(cn1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O2/c1-18-22(16-31)27(36-30(32)34-18)37-15-7-12-24(37)28-35-23-11-6-10-21(19-13-14-25(40-2)33-17-19)26(23)29(39)38(28)20-8-4-3-5-9-20/h3-6,8-11,13-14,17,24H,7,12,15H2,1-2H3,(H2,32,34,36)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362703 (US9840498, 30) Show SMILES Cc1nc(N)nc(N2C[C@@H](F)C[C@H]2c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-21(12-30)25(35-28(31)33-16)37-15-18(29)11-23(37)26-34-22-10-6-9-20(17-13-32-36(2)14-17)24(22)27(39)38(26)19-7-4-3-5-8-19/h3-10,13-14,18,23H,11,15H2,1-2H3,(H2,31,33,35)/t18-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362675 (US9840498, 1) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N Show InChI InChI=1S/C28H24FN9O2/c1-15-19(11-30)25(35-28(31)33-15)37-14-18(39)10-22(37)26-34-21-9-8-20(29)23(16-12-32-36(2)13-16)24(21)27(40)38(26)17-6-4-3-5-7-17/h3-9,12-13,18,22,39H,10,14H2,1-2H3,(H2,31,33,35)/t18-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362684 (US9840498, 10) Show SMILES CO[C@H]1C[C@H](N(C1)c1nc(N)nc(C)c1C#N)c1nc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C29H27N9O2/c1-17-22(13-30)26(35-29(31)33-17)37-16-20(40-3)12-24(37)27-34-23-11-7-10-21(18-14-32-36(2)15-18)25(23)28(39)38(27)19-8-5-4-6-9-19/h4-11,14-15,20,24H,12,16H2,1-3H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362685 (US9840498, 11) Show SMILES CO[C@H]1C[C@H](N(C1)c1nc(N)nc2[nH]cnc12)c1nc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362690 (US9840498, 16) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H25N9O2/c1-16-21(12-29)25(34-28(30)32-16)36-15-19(38)11-23(36)26-33-22-10-6-9-20(17-13-31-35(2)14-17)24(22)27(39)37(26)18-7-4-3-5-8-18/h3-10,13-14,19,23,38H,11,15H2,1-2H3,(H2,30,32,34)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362692 (US9840498, 18) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O2/c1-18-23(15-31)27(36-30(32)34-18)37-13-7-12-25(37)28-35-24-11-6-10-22(19-14-21(40-2)17-33-16-19)26(24)29(39)38(28)20-8-4-3-5-9-20/h3-6,8-11,14,16-17,25H,7,12-13H2,1-2H3,(H2,32,34,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362680 (US9840498, 6) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-19(13-30)25(35-28(31)33-16)37-12-6-9-22(37)26-34-21-11-10-20(29)23(17-14-32-36(2)15-17)24(21)27(39)38(26)18-7-4-3-5-8-18/h3-5,7-8,10-11,14-15,22H,6,9,12H2,1-2H3,(H2,31,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362700 (US9840498, 27) Show SMILES COc1ccc(cn1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-22(14-31)27(36-30(32)34-17)37-16-20(39)13-24(37)28-35-23-10-6-9-21(18-11-12-25(41-2)33-15-18)26(23)29(40)38(28)19-7-4-3-5-8-19/h3-12,15,20,24,39H,13,16H2,1-2H3,(H2,32,34,36)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362698 (US9840498, 25) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-23(13-31)27(36-30(32)34-17)37-16-20(39)12-25(37)28-35-24-10-6-9-22(18-11-21(41-2)15-33-14-18)26(24)29(40)38(28)19-7-4-3-5-8-19/h3-11,14-15,20,25,39H,12,16H2,1-2H3,(H2,32,34,36)/t20-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362688 (US9840498, 14) Show SMILES Cc1ccccc1-n1c(nc2cccc(-c3cnn(C)c3)c2c1=O)[C@@H]1CCCN1c1ncnc(N)c1C#N |r,wD:24.27,(.62,4.67,;1.95,3.9,;3.28,4.67,;4.62,3.9,;4.62,2.36,;3.28,1.59,;1.95,2.36,;.62,1.59,;.62,.05,;-.72,-.72,;-2.05,.05,;-3.38,-.72,;-4.72,.05,;-4.72,1.59,;-3.38,2.36,;-3.38,3.9,;-2.14,4.8,;-2.61,6.27,;-4.15,6.27,;-4.92,7.6,;-4.63,4.8,;-2.05,1.59,;-.72,2.36,;-.72,3.9,;1.95,-.72,;3.41,-.25,;4.32,-1.49,;3.41,-2.74,;1.95,-2.26,;1.18,-3.6,;-.36,-3.6,;-1.13,-4.93,;-.36,-6.27,;1.18,-6.27,;1.95,-7.6,;1.95,-4.93,;3.44,-5.33,;4.92,-5.73,)| Show InChI InChI=1S/C28H25N9O/c1-17-7-3-4-10-22(17)37-27(23-11-6-12-36(23)26-20(13-29)25(30)31-16-32-26)34-21-9-5-8-19(24(21)28(37)38)18-14-33-35(2)15-18/h3-5,7-10,14-16,23H,6,11-12H2,1-2H3,(H2,30,31,32)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362675 (US9840498, 1) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N Show InChI InChI=1S/C28H24FN9O2/c1-15-19(11-30)25(35-28(31)33-15)37-14-18(39)10-22(37)26-34-21-9-8-20(29)23(16-12-32-36(2)13-16)24(21)27(40)38(26)17-6-4-3-5-7-17/h3-9,12-13,18,22,39H,10,14H2,1-2H3,(H2,31,33,35)/t18-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362697 (US9840498, 24) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O2/c1-17-22(14-30)26(35-29(31)33-17)36-16-20(38)13-24(36)27-34-23-11-5-10-21(18-7-6-12-32-15-18)25(23)28(39)37(27)19-8-3-2-4-9-19/h2-12,15,20,24,38H,13,16H2,1H3,(H2,31,33,35)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362706 (US9840498, 33) Show SMILES Nc1ncnc(N2CCC[C@H]2c2nc3cccc(C#CCO)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C26H21N7O2/c27-15-19-23(28)29-16-30-24(19)32-13-5-12-21(32)25-31-20-11-4-7-17(8-6-14-34)22(20)26(35)33(25)18-9-2-1-3-10-18/h1-4,7,9-11,16,21,34H,5,12-14H2,(H2,28,29,30)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362678 (US9840498, 4) Show SMILES COc1ncc(cn1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C29H25N9O2/c1-17-21(14-30)25(36-28(31)34-17)37-13-7-12-23(37)26-35-22-11-6-10-20(18-15-32-29(40-2)33-16-18)24(22)27(39)38(26)19-8-4-3-5-9-19/h3-6,8-11,15-16,23H,7,12-13H2,1-2H3,(H2,31,34,36)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362679 (US9840498, 5) Show SMILES Cn1cc(cn1)-c1c(F)ccc2nc([C@@H]3CCCN3c3ncnc(N)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C27H22FN9O/c1-35-14-16(13-33-35)22-19(28)9-10-20-23(22)27(38)37(17-6-3-2-4-7-17)26(34-20)21-8-5-11-36(21)25-18(12-29)24(30)31-15-32-25/h2-4,6-7,9-10,13-15,21H,5,8,11H2,1H3,(H2,30,31,32)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362700 (US9840498, 27) Show SMILES COc1ccc(cn1)-c1cccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O3/c1-17-22(14-31)27(36-30(32)34-17)37-16-20(39)13-24(37)28-35-23-10-6-9-21(18-11-12-25(41-2)33-15-18)26(23)29(40)38(28)19-7-4-3-5-8-19/h3-12,15,20,24,39H,13,16H2,1-2H3,(H2,32,34,36)/t20-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362692 (US9840498, 18) Show SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3CCCN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C30H26N8O2/c1-18-23(15-31)27(36-30(32)34-18)37-13-7-12-25(37)28-35-24-11-6-10-22(19-14-21(40-2)17-33-16-19)26(24)29(39)38(28)20-8-4-3-5-9-20/h3-6,8-11,14,16-17,25H,7,12-13H2,1-2H3,(H2,32,34,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair

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