Compile Data Set for Download or QSAR

Found 204 hits Enz. Inhib. hit(s) with all data for entry = 9133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444416 (US10662159, Example 1) Show SMILES FC(F)(F)C(OC(=O)N1CCc2ccccc2C1)C(F)(F)F Show InChI InChI=1S/C13H11F6NO2/c14-12(15,16)10(13(17,18)19)22-11(21)20-6-5-8-3-1-2-4-9(8)7-20/h1-4,10H,5-7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM444474 (US10662159, Example 67 | US10662159, Example 68) Show SMILES Fc1ccc(cc1)C(OC1CC2(C1)CCN(C2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1 |(-8.79,-.56,;-7.25,-.56,;-6.48,-1.9,;-4.94,-1.9,;-4.17,-.56,;-4.94,.77,;-6.48,.77,;-2.63,-.56,;-1.86,.77,;-.32,.77,;.77,-.32,;1.86,.77,;.77,1.86,;2.76,2.02,;4.23,1.54,;4.23,,;2.76,-.48,;5.47,-.91,;5.31,-2.44,;6.88,-.28,;8.13,-1.18,;9.53,-.56,;10.94,.07,;8.91,.85,;10.16,-1.96,;7.97,-2.72,;7.81,-4.25,;6.43,-2.55,;9.5,-2.88,;-1.86,-1.9,;-.32,-1.9,;.45,-3.23,;-.32,-4.56,;.45,-5.9,;-1.86,-4.56,;-2.63,-3.23,)| Show InChI InChI=1S/C24H21F8NO3/c25-16-5-1-14(2-6-16)19(15-3-7-17(26)8-4-15)35-18-11-22(12-18)9-10-33(13-22)21(34)36-20(23(27,28)29)24(30,31)32/h1-8,18-20H,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444423 (US10662159, Example 8) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(Br)cc2C1)C(F)(F)F Show InChI InChI=1S/C12H8BrF6NO2/c13-8-2-1-6-4-20(5-7(6)3-8)10(21)22-9(11(14,15)16)12(17,18)19/h1-3,9H,4-5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444424 (US10662159, Example 9) Show SMILES Oc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C12H9F6NO3/c13-11(14,15)9(12(16,17)18)22-10(21)19-4-6-1-2-8(20)3-7(6)5-19/h1-3,9,20H,4-5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444431 (US10662159, Example 16) Show SMILES FC(F)(F)C(OC(=O)N1CCc2c(Br)cccc2C1)C(F)(F)F Show InChI InChI=1S/C13H10BrF6NO2/c14-9-3-1-2-7-6-21(5-4-8(7)9)11(22)23-10(12(15,16)17)13(18,19)20/h1-3,10H,4-6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444432 (US10662159, Example 17) Show SMILES FC(F)(F)C(OC(=O)N1CCc2cc(Br)ccc2C1)C(F)(F)F Show InChI InChI=1S/C13H10BrF6NO2/c14-9-2-1-8-6-21(4-3-7(8)5-9)11(22)23-10(12(15,16)17)13(18,19)20/h1-2,5,10H,3-4,6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444434 (US10662159, Example 19) Show SMILES COc1cccc2CN(Cc12)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C13H11F6NO3/c1-22-9-4-2-3-7-5-20(6-8(7)9)11(21)23-10(12(14,15)16)13(17,18)19/h2-4,10H,5-6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444436 (US10662159, Example 21) Show SMILES COc1cc2CN(Cc2cc1OC)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H13F6NO4/c1-23-9-3-7-5-21(6-8(7)4-10(9)24-2)12(22)25-11(13(15,16)17)14(18,19)20/h3-4,11H,5-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444437 (US10662159, Example 22) Show SMILES COc1cccc2CN(CCc12)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H13F6NO3/c1-23-10-4-2-3-8-7-21(6-5-9(8)10)12(22)24-11(13(15,16)17)14(18,19)20/h2-4,11H,5-7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444438 (US10662159, Example 23) Show SMILES COc1ccc2CN(CCc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H13F6NO3/c1-23-10-3-2-9-7-21(5-4-8(9)6-10)12(22)24-11(13(15,16)17)14(18,19)20/h2-3,6,11H,4-5,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444440 (US10662159, Example 25) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(cc2C1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C18H13F6NO2/c19-17(20,21)15(18(22,23)24)27-16(26)25-9-13-7-6-12(8-14(13)10-25)11-4-2-1-3-5-11/h1-8,15H,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444441 (US10662159, Example 26) Show SMILES COc1ccc(cc1F)-c1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H14F7NO3/c1-29-15-5-4-11(7-14(15)20)10-2-3-12-8-27(9-13(12)6-10)17(28)30-16(18(21,22)23)19(24,25)26/h2-7,16H,8-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444445 (US10662159, Example 30) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(cc2C1)N1CCCC1)C(F)(F)F Show InChI InChI=1S/C16H16F6N2O2/c17-15(18,19)13(16(20,21)22)26-14(25)24-8-10-3-4-12(7-11(10)9-24)23-5-1-2-6-23/h3-4,7,13H,1-2,5-6,8-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444446 (US10662159, Example 31) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(cc2C1)N1CCS(=O)(=O)CC1)C(F)(F)F Show InChI InChI=1S/C16H16F6N2O4S/c17-15(18,19)13(16(20,21)22)28-14(25)24-8-10-1-2-12(7-11(10)9-24)23-3-5-29(26,27)6-4-23/h1-2,7,13H,3-6,8-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444447 (US10662159, Example 32) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(cc2C1)N1CCOCC1)C(F)(F)F Show InChI InChI=1S/C16H16F6N2O3/c17-15(18,19)13(16(20,21)22)27-14(25)24-8-10-1-2-12(7-11(10)9-24)23-3-5-26-6-4-23/h1-2,7,13H,3-6,8-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444448 (US10662159, Example 35) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CCc3c(Br)cccc3C1)C2=O Show InChI InChI=1S/C17H17BrN2O4/c1-17(2)12-13(17)15(22)20(14(12)21)24-16(23)19-7-6-10-9(8-19)4-3-5-11(10)18/h3-5,12-13H,6-8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444451 (US10662159, Example 39) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1Cc3ccc(cc3C1)N1CCOCC1)C2=O Show InChI InChI=1S/C20H23N3O5/c1-20(2)15-16(20)18(25)23(17(15)24)28-19(26)22-10-12-3-4-14(9-13(12)11-22)21-5-7-27-8-6-21/h3-4,9,15-16H,5-8,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444452 (US10662159, Example 40) Show SMILES OC[C@@H](OC(=O)N1CCc2c(Br)cccc2C1)C(F)(F)F Show InChI InChI=1S/C13H13BrF3NO3/c14-10-3-1-2-8-6-18(5-4-9(8)10)12(20)21-11(7-19)13(15,16)17/h1-3,11,19H,4-7H2/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444453 (US10662159, Example 41) Show SMILES FCCCOc1cccc2CN(CCc12)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H16F7NO3/c17-6-2-8-26-12-4-1-3-10-9-24(7-5-11(10)12)14(25)27-13(15(18,19)20)16(21,22)23/h1,3-4,13H,2,5-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444454 (US10662159, Example 42) Show SMILES FCCCOc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H14F7NO3/c16-4-1-5-25-11-3-2-9-7-23(8-10(9)6-11)13(24)26-12(14(17,18)19)15(20,21)22/h2-3,6,12H,1,4-5,7-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444455 (US10662159, Example 43) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCC3CC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C16H15F6NO3/c17-15(18,19)13(16(20,21)22)26-14(24)23-6-10-3-4-12(5-11(10)7-23)25-8-9-1-2-9/h3-5,9,13H,1-2,6-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444457 (US10662159, Example 45) Show SMILES FC(F)COc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H11F8NO3/c15-10(16)6-25-9-2-1-7-4-23(5-8(7)3-9)12(24)26-11(13(17,18)19)14(20,21)22/h1-3,10-11H,4-6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444457 (US10662159, Example 45) Show SMILES FC(F)COc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H11F8NO3/c15-10(16)6-25-9-2-1-7-4-23(5-8(7)3-9)12(24)26-11(13(17,18)19)14(20,21)22/h1-3,10-11H,4-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444458 (US10662159, Example 46) Show SMILES CN(C)CCOc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H18F6N2O3/c1-23(2)5-6-26-12-4-3-10-8-24(9-11(10)7-12)14(25)27-13(15(17,18)19)16(20,21)22/h3-4,7,13H,5-6,8-9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444458 (US10662159, Example 46) Show SMILES CN(C)CCOc1ccc2CN(Cc2c1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H18F6N2O3/c1-23(2)5-6-26-12-4-3-10-8-24(9-11(10)7-12)14(25)27-13(15(17,18)19)16(20,21)22/h3-4,7,13H,5-6,8-9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444459 (US10662159, Example 47) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(NCCN3CCOCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H21F6N3O3/c19-17(20,21)15(18(22,23)24)30-16(28)27-10-12-1-2-14(9-13(12)11-27)25-3-4-26-5-7-29-8-6-26/h1-2,9,15,25H,3-8,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444460 (US10662159, Example 48) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCCN3CCCCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C19H22F6N2O3/c20-18(21,22)16(19(23,24)25)30-17(28)27-11-13-4-5-15(10-14(13)12-27)29-9-8-26-6-2-1-3-7-26/h4-5,10,16H,1-3,6-9,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444460 (US10662159, Example 48) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCCN3CCCCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C19H22F6N2O3/c20-18(21,22)16(19(23,24)25)30-17(28)27-11-13-4-5-15(10-14(13)12-27)29-9-8-26-6-2-1-3-7-26/h4-5,10,16H,1-3,6-9,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444461 (US10662159, Example 49) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCCN3CCCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H20F6N2O3/c19-17(20,21)15(18(22,23)24)29-16(27)26-10-12-3-4-14(9-13(12)11-26)28-8-7-25-5-1-2-6-25/h3-4,9,15H,1-2,5-8,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444461 (US10662159, Example 49) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCCN3CCCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H20F6N2O3/c19-17(20,21)15(18(22,23)24)29-16(27)26-10-12-3-4-14(9-13(12)11-26)28-8-7-25-5-1-2-6-25/h3-4,9,15H,1-2,5-8,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444462 (US10662159, Example 50) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCC(=O)N3CCOCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H18F6N2O5/c19-17(20,21)15(18(22,23)24)31-16(28)26-8-11-1-2-13(7-12(11)9-26)30-10-14(27)25-3-5-29-6-4-25/h1-2,7,15H,3-6,8-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444462 (US10662159, Example 50) Show SMILES FC(F)(F)C(OC(=O)N1Cc2ccc(OCC(=O)N3CCOCC3)cc2C1)C(F)(F)F Show InChI InChI=1S/C18H18F6N2O5/c19-17(20,21)15(18(22,23)24)31-16(28)26-8-11-1-2-13(7-12(11)9-26)30-10-14(27)25-3-5-29-6-4-25/h1-2,7,15H,3-6,8-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444463 (US10662159, Example 52) Show SMILES FC(F)(F)C(OC(=O)N1CC2(CC(C2)Oc2cccc(c2)C(F)(F)F)C1)C(F)(F)F Show InChI InChI=1S/C17H14F9NO3/c18-15(19,20)9-2-1-3-10(4-9)29-11-5-14(6-11)7-27(8-14)13(28)30-12(16(21,22)23)17(24,25)26/h1-4,11-12H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444463 (US10662159, Example 52) Show SMILES FC(F)(F)C(OC(=O)N1CC2(CC(C2)Oc2cccc(c2)C(F)(F)F)C1)C(F)(F)F Show InChI InChI=1S/C17H14F9NO3/c18-15(19,20)9-2-1-3-10(4-9)29-11-5-14(6-11)7-27(8-14)13(28)30-12(16(21,22)23)17(24,25)26/h1-4,11-12H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444464 (US10662159, Example 53) Show SMILES Fc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C16H14F7NO3/c17-9-2-1-3-10(4-9)26-11-5-14(6-11)7-24(8-14)13(25)27-12(15(18,19)20)16(21,22)23/h1-4,11-12H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444464 (US10662159, Example 53) Show SMILES Fc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C16H14F7NO3/c17-9-2-1-3-10(4-9)26-11-5-14(6-11)7-24(8-14)13(25)27-12(15(18,19)20)16(21,22)23/h1-4,11-12H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444465 (US10662159, Example 54) Show SMILES COc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C17H17F6NO4/c1-26-10-3-2-4-11(5-10)27-12-6-15(7-12)8-24(9-15)14(25)28-13(16(18,19)20)17(21,22)23/h2-5,12-13H,6-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444466 (US10662159, Example 55) Show SMILES FC(F)(F)C(OC(=O)N1CC2(CC(C2)Oc2cccc(Oc3ccccc3)c2)C1)C(F)(F)F Show InChI InChI=1S/C22H19F6NO4/c23-21(24,25)18(22(26,27)28)33-19(30)29-12-20(13-29)10-17(11-20)32-16-8-4-7-15(9-16)31-14-5-2-1-3-6-14/h1-9,17-18H,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444467 (US10662159, Example 56) Show SMILES FC(F)(F)Oc1cccc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C17H14F9NO4/c18-15(19,20)12(16(21,22)23)30-13(28)27-7-14(8-27)5-11(6-14)29-9-2-1-3-10(4-9)31-17(24,25)26/h1-4,11-12H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444476 (US10662159, Example 57) Show SMILES Fc1cccc(OC2C[C@@]3(C2)CCN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 |r,wU:9.9,(-17.05,-2.89,;-15.52,-3.05,;-14.89,-4.46,;-13.36,-4.62,;-12.46,-3.38,;-13.08,-1.97,;-12.18,-.72,;-10.65,-.88,;-9.68,-2.08,;-8.48,-1.11,;-9.45,.08,;-7.71,-2.45,;-6.2,-2.13,;-6.04,-.59,;-7.45,.03,;-4.71,.18,;-3.38,-.59,;-4.71,1.72,;-3.38,2.49,;-3.38,4.03,;-3.38,5.57,;-1.84,4.03,;-4.92,4.03,;-2.04,1.72,;-2.81,.38,;-1.27,3.05,;-.71,.95,;-14.62,-1.81,)| Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-7-15(8-12)4-5-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2/t12?,15-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444468 (US10662159, Example 58) Show SMILES Fc1cccc(OC2C[C@@]3(C2)CCN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 |r,wD:9.8,(-17.05,-2.89,;-15.52,-3.05,;-14.89,-4.46,;-13.36,-4.62,;-12.46,-3.38,;-13.08,-1.97,;-12.18,-.72,;-10.65,-.88,;-9.45,.08,;-8.48,-1.11,;-9.68,-2.08,;-7.71,-2.45,;-6.2,-2.13,;-6.04,-.59,;-7.45,.03,;-4.71,.18,;-3.38,-.59,;-4.71,1.72,;-3.38,2.49,;-3.38,4.03,;-3.38,5.57,;-1.84,4.03,;-4.92,4.03,;-2.04,1.72,;-2.81,.38,;-1.27,3.05,;-.71,.95,;-14.62,-1.81,)| Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-7-15(8-12)4-5-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2/t12?,15-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444469 (US10662159, Example 59) Show SMILES Fc1cccc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-4-5-15(7-12)8-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444469 (US10662159, Example 59) Show SMILES Fc1cccc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-4-5-15(7-12)8-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM444469 (US10662159, Example 59) Show SMILES Fc1cccc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C17H16F7NO3/c18-10-2-1-3-11(6-10)27-12-4-5-15(7-12)8-25(9-15)14(26)28-13(16(19,20)21)17(22,23)24/h1-3,6,12-13H,4-5,7-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444470 (US10662159, Example 60) Show SMILES Fc1cncc(OC2CC3(C2)CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C15H13F7N2O3/c16-8-1-9(5-23-4-8)26-10-2-13(3-10)6-24(7-13)12(25)27-11(14(17,18)19)15(20,21)22/h1,4-5,10-11H,2-3,6-7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444471 (US10662159, Example 61) Show SMILES Fc1cncc(OC2CCC3(CN(C3)C(=O)OC(C(F)(F)F)C(F)(F)F)C2)c1 Show InChI InChI=1S/C16H15F7N2O3/c17-9-3-11(6-24-5-9)27-10-1-2-14(4-10)7-25(8-14)13(26)28-12(15(18,19)20)16(21,22)23/h3,5-6,10,12H,1-2,4,7-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444472 (US10662159, Example 63) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(CC(C3)Oc3cccc(c3)C(F)(F)F)C1)C2=O Show InChI InChI=1S/C21H21F3N2O5/c1-19(2)14-15(19)17(28)26(16(14)27)31-18(29)25-9-20(10-25)7-13(8-20)30-12-5-3-4-11(6-12)21(22,23)24/h3-6,13-15H,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444473 (US10662159, Example 64) Show SMILES CC1(C)C2C1C(=O)N(OC(=O)N1CC3(C1)CCC(C3)Oc1cncc(F)c1)C2=O Show InChI InChI=1S/C20H22FN3O5/c1-19(2)14-15(19)17(26)24(16(14)25)29-18(27)23-9-20(10-23)4-3-12(6-20)28-13-5-11(21)7-22-8-13/h5,7-8,12,14-15H,3-4,6,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM444474 (US10662159, Example 67 | US10662159, Example 68) Show SMILES Fc1ccc(cc1)C(OC1CC2(C1)CCN(C2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1 |(-8.79,-.56,;-7.25,-.56,;-6.48,-1.9,;-4.94,-1.9,;-4.17,-.56,;-4.94,.77,;-6.48,.77,;-2.63,-.56,;-1.86,.77,;-.32,.77,;.77,-.32,;1.86,.77,;.77,1.86,;2.76,2.02,;4.23,1.54,;4.23,,;2.76,-.48,;5.47,-.91,;5.31,-2.44,;6.88,-.28,;8.13,-1.18,;9.53,-.56,;10.94,.07,;8.91,.85,;10.16,-1.96,;7.97,-2.72,;7.81,-4.25,;6.43,-2.55,;9.5,-2.88,;-1.86,-1.9,;-.32,-1.9,;.45,-3.23,;-.32,-4.56,;.45,-5.9,;-1.86,-4.56,;-2.63,-3.23,)| Show InChI InChI=1S/C24H21F8NO3/c25-16-5-1-14(2-6-16)19(15-3-7-17(26)8-4-15)35-18-11-22(12-18)9-10-33(13-22)21(34)36-20(23(27,28)29)24(30,31)32/h1-8,18-20H,9-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM444474 (US10662159, Example 67 | US10662159, Example 68) Show SMILES Fc1ccc(cc1)C(OC1CC2(C1)CCN(C2)C(=O)OC(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1 |(-8.79,-.56,;-7.25,-.56,;-6.48,-1.9,;-4.94,-1.9,;-4.17,-.56,;-4.94,.77,;-6.48,.77,;-2.63,-.56,;-1.86,.77,;-.32,.77,;.77,-.32,;1.86,.77,;.77,1.86,;2.76,2.02,;4.23,1.54,;4.23,,;2.76,-.48,;5.47,-.91,;5.31,-2.44,;6.88,-.28,;8.13,-1.18,;9.53,-.56,;10.94,.07,;8.91,.85,;10.16,-1.96,;7.97,-2.72,;7.81,-4.25,;6.43,-2.55,;9.5,-2.88,;-1.86,-1.9,;-.32,-1.9,;.45,-3.23,;-.32,-4.56,;.45,-5.9,;-1.86,-4.56,;-2.63,-3.23,)| Show InChI InChI=1S/C24H21F8NO3/c25-16-5-1-14(2-6-16)19(15-3-7-17(26)8-4-15)35-18-11-22(12-18)9-10-33(13-22)21(34)36-20(23(27,28)29)24(30,31)32/h1-8,18-20H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
MAKSCIENTIFIC, LLC US Patent					Assay Description MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...				US Patent US10662159 (2020) BindingDB Entry DOI: 10.7270/Q2RB77NZ
					More data for this Ligand-Target Pair

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