Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Leucine aminopeptidase | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50017478 (Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | MMDB Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50225458 ((2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroc£?aw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney cytosolic leucine aminopeptidase | Bioorg Med Chem Lett 18: 1550-4 (2008) Article DOI: 10.1016/j.bmcl.2008.01.107 BindingDB Entry DOI: 10.7270/Q28K78TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50457478 (CHEMBL4208547) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of LAP (unknown origin) | J Med Chem 61: 6468-6490 (2018) Article DOI: 10.1021/acs.jmedchem.7b00782 BindingDB Entry DOI: 10.7270/Q28S4SHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129685 (2-Amino-4-methyl-pentanal | CHEMBL88476) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of LAP | J Med Chem 54: 5955-80 (2011) Article DOI: 10.1021/jm200587f BindingDB Entry DOI: 10.7270/Q2PV6MGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129684 (3-[(1-amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroc£?aw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney cytosolic leucine aminopeptidase | Bioorg Med Chem Lett 18: 1550-4 (2008) Article DOI: 10.1016/j.bmcl.2008.01.107 BindingDB Entry DOI: 10.7270/Q28K78TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129684 (3-[(1-amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129681 (3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129682 (2-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoylme...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50089610 ((Z)-(S)-5-Amino-7-methyl-4-oxo-oct-2-enoic acid me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Queen's University of Belfast Curated by ChEMBL | Assay Description Inhibitory activity of the compound against leucine aminopeptidase | Bioorg Med Chem Lett 10: 1481-2 (2000) BindingDB Entry DOI: 10.7270/Q2BV7FVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027041 (2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-4-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50017478 (Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | MMDB PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Effect of inhibitor structure on the slow binding inhibition of Leucine aminopeptidase was determined and the Ki was reported which is = k2/k1 | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50017478 (Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | MMDB PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024594 ((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Leucine aminopeptidase isolated from porcine kidney. | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129679 ((1-Amino-3-methyl-butyl)-phosphonic acid | 1-amino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50316047 (1-amino-2-methylbutylphosphonic acid monophenylest...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of leucine aminopeptidase | Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129679 ((1-Amino-3-methyl-butyl)-phosphonic acid | 1-amino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of leucine aminopeptidase | Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50234656 ((R)-3-[((R)-1-amino-3-phenyl-propyl)-hydroxy-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 271 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroc£?aw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney cytosolic leucine aminopeptidase | Bioorg Med Chem Lett 18: 1550-4 (2008) Article DOI: 10.1016/j.bmcl.2008.01.107 BindingDB Entry DOI: 10.7270/Q28K78TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50022747 (2-(3-Amino-2-hydroxy-4-phenyl-thiobutyrylamino)-4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Leucine aminopeptidase | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129677 (3-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyl]-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50316048 (1-amino-2-phenylethylphosphonic acid monophenyl es...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of leucine aminopeptidase | Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024596 ((R)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Leucine aminopeptidase isolated from porcine kidney. | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024592 ((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of leucine aminopeptidase | Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024590 (1-Ammonium-octane-1-phosphonic acid anion | CHEMBL...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se... | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027043 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase from porcine kidney and the inhibition constant was determined after preincubatin... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Bos taurus (bovine)) | BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Haute Alsace Curated by ChEMBL | Assay Description Competitive inhibition of bovine LAPc using L-leucine-p-nitroanilide as substrate by spectrophotometric analysis | Bioorg Med Chem 20: 4942-53 (2012) Article DOI: 10.1016/j.bmc.2012.06.041 BindingDB Entry DOI: 10.7270/Q2RB75Q1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Leucine aminopeptidase | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50022751 (2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Aminopeptidase M | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027042 (3-Amino-2-hydroxy-5-methyl-hexanoic acid {2-methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and in... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50225458 ((2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 988 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroc£?aw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney cytosolic leucine aminopeptidase | Bioorg Med Chem Lett 18: 1550-4 (2008) Article DOI: 10.1016/j.bmcl.2008.01.107 BindingDB Entry DOI: 10.7270/Q28K78TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50022751 (2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Leucine aminopeptidase | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024601 (1-Ammonium-hexane-1-phosphonic acid anion | 1-amin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Leucine aminopeptidase isolated from porcine kidney. | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024602 (1-Ammonium-2-methyl-propane-1-phosphonic acid anio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se... | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027046 (2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50457469 (CHEMBL4213478) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of LAP (unknown origin) | J Med Chem 61: 6468-6490 (2018) Article DOI: 10.1021/acs.jmedchem.7b00782 BindingDB Entry DOI: 10.7270/Q28S4SHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024604 (1-Ammonium-propane-1-phosphonic acid anion | 1-ami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se... | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50022742 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-thio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin Curated by ChEMBL | Assay Description Inhibitory activity against Leucine aminopeptidase | J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50129680 (CHEMBL423870 | {[hydroxy(1-hydroxy-3-methylbutyl)p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney | J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50234656 ((R)-3-[((R)-1-amino-3-phenyl-propyl)-hydroxy-phosp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroc£?aw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney cytosolic leucine aminopeptidase | Bioorg Med Chem Lett 18: 1550-4 (2008) Article DOI: 10.1016/j.bmcl.2008.01.107 BindingDB Entry DOI: 10.7270/Q28K78TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Bos taurus (bovine)) | BDBM23983 (3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+4 | -29.0 | n/a | n/a | n/a | n/a | n/a | 8.0 | 30 |
ENSCMu | Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t... | Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50024592 ((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Leucine aminopeptidase isolated from porcine kidney. | J Med Chem 30: 1603-9 (1987) BindingDB Entry DOI: 10.7270/Q2W66MCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50046325 ((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027045 (2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Effect of inhibitor structure on the slow binding inhibition of Aminopeptidase M from porcine kidney was determined and the Ki was reported which is ... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50017478 (Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | MMDB PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1 | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50367209 (BESTATIN HYDROCHLORIDE | Ubenimex) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosol aminopeptidase (Homo sapiens (Human)) | BDBM50027045 (2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | <2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in... | J Med Chem 27: 417-22 (1984) BindingDB Entry DOI: 10.7270/Q280535G | |||||||||||
More data for this Ligand-Target Pair |
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