Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM5446
(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242522
(CHEMBL4061297)Show SMILES Nc1nc(NCc2ccc(Cl)cc2)c2c(n1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C17H14ClN5O/c18-10-3-1-9(2-4-10)8-20-15-14-12-7-11(24)5-6-13(12)21-16(14)23-17(19)22-15/h1-7,24H,8H2,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242544
(CHEMBL4080640)Show InChI InChI=1S/C18H17N5O/c1-10-2-4-11(5-3-10)9-20-16-15-13-8-12(24)6-7-14(13)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242545
(CHEMBL4083162)Show SMILES Cc1cc2[nH]c3nc(N)nc(NCc4ccc(Cl)cc4)c3c2cc1O Show InChI InChI=1S/C18H16ClN5O/c1-9-6-13-12(7-14(9)25)15-16(23-18(20)24-17(15)22-13)21-8-10-2-4-11(19)5-3-10/h2-7,25H,8H2,1H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242520
(CHEMBL4099589)Show InChI InChI=1S/C18H17N5O2/c1-25-12-5-2-10(3-6-12)9-20-16-15-13-8-11(24)4-7-14(13)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242543
(CHEMBL4090945)Show SMILES Nc1nc(NCc2ccccc2)c2c(n1)[nH]c1cc(Cl)c(O)cc21 Show InChI InChI=1S/C17H14ClN5O/c18-11-7-12-10(6-13(11)24)14-15(22-17(19)23-16(14)21-12)20-8-9-4-2-1-3-5-9/h1-7,24H,8H2,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242550
(CHEMBL4070420)Show SMILES Nc1nc(NCc2cccc(Cl)c2)c2c(n1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C17H14ClN5O/c18-10-3-1-2-9(6-10)8-20-15-14-12-7-11(24)4-5-13(12)21-16(14)23-17(19)22-15/h1-7,24H,8H2,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242542
(CHEMBL4069965)Show SMILES Nc1nc(NCc2ccccc2)c2c(n1)[nH]c1cc(Br)c(O)cc21 Show InChI InChI=1S/C17H14BrN5O/c18-11-7-12-10(6-13(11)24)14-15(22-17(19)23-16(14)21-12)20-8-9-4-2-1-3-5-9/h1-7,24H,8H2,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242535
(CHEMBL4099089)Show SMILES C[C@H](Nc1nc(N)nc2[nH]c3ccc(O)cc3c12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O/c1-10(11-5-3-2-4-6-11)20-16-15-13-9-12(24)7-8-14(13)21-17(15)23-18(19)22-16/h2-10,24H,1H3,(H4,19,20,21,22,23)/t10-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242541
(CHEMBL4073523)Show InChI InChI=1S/C18H17N5O2/c1-25-14-8-12-11(7-13(14)24)15-16(22-18(19)23-17(15)21-12)20-9-10-5-3-2-4-6-10/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242540
(CHEMBL4094157)Show InChI InChI=1S/C18H17N5O/c1-10-7-13-12(8-14(10)24)15-16(22-18(19)23-17(15)21-13)20-9-11-5-3-2-4-6-11/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242528
(CHEMBL4060727)Show InChI InChI=1S/C18H17N5O/c19-18-22-16(20-9-8-11-4-2-1-3-5-11)15-13-10-12(24)6-7-14(13)21-17(15)23-18/h1-7,10,24H,8-9H2,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242536
(CHEMBL3715932)Show InChI InChI=1S/C17H15N5O/c18-17-21-15(19-9-10-4-2-1-3-5-10)14-12-8-11(23)6-7-13(12)20-16(14)22-17/h1-8,23H,9H2,(H4,18,19,20,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242524
(CHEMBL4102074)Show InChI InChI=1S/C18H17N5O2/c1-25-14-5-3-2-4-10(14)9-20-16-15-12-8-11(24)6-7-13(12)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242526
(CHEMBL4083567)Show SMILES Cc1cc2[nH]c3nc(N)nc(NCc4cccc(Cl)c4)c3c2cc1O Show InChI InChI=1S/C18H16ClN5O/c1-9-5-13-12(7-14(9)25)15-16(23-18(20)24-17(15)22-13)21-8-10-3-2-4-11(19)6-10/h2-7,25H,8H2,1H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242534
(CHEMBL4088941)Show SMILES C[C@@H](Nc1nc(N)nc2[nH]c3ccc(O)cc3c12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O/c1-10(11-5-3-2-4-6-11)20-16-15-13-9-12(24)7-8-14(13)21-17(15)23-18(19)22-16/h2-10,24H,1H3,(H4,19,20,21,22,23)/t10-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242523
(CHEMBL4084090)Show InChI InChI=1S/C18H17N5O2/c1-25-12-4-2-3-10(7-12)9-20-16-15-13-8-11(24)5-6-14(13)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242524
(CHEMBL4102074)Show InChI InChI=1S/C18H17N5O2/c1-25-14-5-3-2-4-10(14)9-20-16-15-12-8-11(24)6-7-13(12)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242534
(CHEMBL4088941)Show SMILES C[C@@H](Nc1nc(N)nc2[nH]c3ccc(O)cc3c12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O/c1-10(11-5-3-2-4-6-11)20-16-15-13-9-12(24)7-8-14(13)21-17(15)23-18(19)22-16/h2-10,24H,1H3,(H4,19,20,21,22,23)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242536
(CHEMBL3715932)Show InChI InChI=1S/C17H15N5O/c18-17-21-15(19-9-10-4-2-1-3-5-10)14-12-8-11(23)6-7-13(12)20-16(14)22-17/h1-8,23H,9H2,(H4,18,19,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242522
(CHEMBL4061297)Show SMILES Nc1nc(NCc2ccc(Cl)cc2)c2c(n1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C17H14ClN5O/c18-10-3-1-9(2-4-10)8-20-15-14-12-7-11(24)5-6-13(12)21-16(14)23-17(19)22-15/h1-7,24H,8H2,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242544
(CHEMBL4080640)Show InChI InChI=1S/C18H17N5O/c1-10-2-4-11(5-3-10)9-20-16-15-13-8-12(24)6-7-14(13)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242527
(CHEMBL4061797)Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4ccc(O)cc4c23)cc1OC Show InChI InChI=1S/C19H19N5O3/c1-26-14-6-3-10(7-15(14)27-2)9-21-17-16-12-8-11(25)4-5-13(12)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242523
(CHEMBL4084090)Show InChI InChI=1S/C18H17N5O2/c1-25-12-4-2-3-10(7-12)9-20-16-15-13-8-11(24)5-6-14(13)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242525
(CHEMBL4091355)Show SMILES COc1ccccc1CNc1nc(N)nc2[nH]c3cc(C)c(O)cc3c12 Show InChI InChI=1S/C19H19N5O2/c1-10-7-13-12(8-14(10)25)16-17(23-19(20)24-18(16)22-13)21-9-11-5-3-4-6-15(11)26-2/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 4.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242535
(CHEMBL4099089)Show SMILES C[C@H](Nc1nc(N)nc2[nH]c3ccc(O)cc3c12)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O/c1-10(11-5-3-2-4-6-11)20-16-15-13-9-12(24)7-8-14(13)21-17(15)23-18(19)22-16/h2-10,24H,1H3,(H4,19,20,21,22,23)/t10-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242528
(CHEMBL4060727)Show InChI InChI=1S/C18H17N5O/c19-18-22-16(20-9-8-11-4-2-1-3-5-11)15-13-10-12(24)6-7-14(13)21-17(15)23-18/h1-7,10,24H,8-9H2,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242540
(CHEMBL4094157)Show InChI InChI=1S/C18H17N5O/c1-10-7-13-12(8-14(10)24)15-16(22-18(19)23-17(15)21-13)20-9-11-5-3-2-4-6-11/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50242521
(CHEMBL4072687)Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O2/c1-10-7-14-13(8-15(10)25)16-17(23-19(20)24-18(16)22-14)21-9-11-3-5-12(26-2)6-4-11/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 5.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242525
(CHEMBL4091355)Show SMILES COc1ccccc1CNc1nc(N)nc2[nH]c3cc(C)c(O)cc3c12 Show InChI InChI=1S/C19H19N5O2/c1-10-7-13-12(8-14(10)25)16-17(23-19(20)24-18(16)22-13)21-9-11-5-3-4-6-15(11)26-2/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 7.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242527
(CHEMBL4061797)Show SMILES COc1ccc(CNc2nc(N)nc3[nH]c4ccc(O)cc4c23)cc1OC Show InChI InChI=1S/C19H19N5O3/c1-26-14-6-3-10(7-15(14)27-2)9-21-17-16-12-8-11(25)4-5-13(12)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50242541
(CHEMBL4073523)Show InChI InChI=1S/C18H17N5O2/c1-25-14-8-12-11(7-13(14)24)15-16(22-18(19)23-17(15)21-12)20-9-10-5-3-2-4-6-10/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal... |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform alpha
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of CK1 alpha (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of PKC alpha (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of MEK1 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of ALK1 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 2
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of MEKK2 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Death-associated protein kinase 1
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of DAPK1 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 21
(Homo sapiens) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of MLK4 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Wee1-like protein kinase
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of Wee1 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Myotonin-protein kinase
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of DMPK (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of IRAK (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of JAK2 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human)) | BDBM50242512
(CHEMBL4098682)Show SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1 Show InChI InChI=1S/C19H19N5O/c1-10-3-5-12(6-4-10)9-21-17-16-13-8-15(25)11(2)7-14(13)22-18(16)24-19(20)23-17/h3-8,25H,9H2,1-2H3,(H4,20,21,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description
Inhibition of MARK1 (unknown origin) |
Bioorg Med Chem Lett 27: 2708-2712 (2017)
Article DOI: 10.1016/j.bmcl.2017.04.053
BindingDB Entry DOI: 10.7270/Q2J67KBT |
More data for this
Ligand-Target Pair | |
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