Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histidinol dehydrogenase, chloroplastic (Brassica oleracea var. capitata) | BDBM50267976![]() ((S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-b...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometry | Bioorg Med Chem Lett 6: 2131-2136 (1996) Article DOI: 10.1016/0960-894X(96)00384-8 BindingDB Entry DOI: 10.7270/Q2D79BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histidinol dehydrogenase, chloroplastic (Brassica oleracea var. capitata) | BDBM50267975![]() ((S)-3-Amino-1-(4-bromo-phenyl)-4-(1H-imidazol-4-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometry | Bioorg Med Chem Lett 6: 2131-2136 (1996) Article DOI: 10.1016/0960-894X(96)00384-8 BindingDB Entry DOI: 10.7270/Q2D79BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histidinol dehydrogenase, chloroplastic (Brassica oleracea var. capitata) | BDBM50287735![]() ((S)-3-Amino-1-(3-amino-phenyl)-4-(1H-imidazol-4-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometry | Bioorg Med Chem Lett 6: 2131-2136 (1996) Article DOI: 10.1016/0960-894X(96)00384-8 BindingDB Entry DOI: 10.7270/Q2D79BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histidinol dehydrogenase, chloroplastic (Brassica oleracea var. capitata) | BDBM50267972![]() ((S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometry | Bioorg Med Chem Lett 6: 2131-2136 (1996) Article DOI: 10.1016/0960-894X(96)00384-8 BindingDB Entry DOI: 10.7270/Q2D79BC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50506948![]() (CHEMBL4448806) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597493![]() (CHEMBL5192610) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50552912![]() (CHEMBL4760047) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM162846![]() (US9056843, 137) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597488![]() (CHEMBL5180112) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243173![]() ((R)-N-(1-(5-Azaspiro[2.5]octan-5- yl)propan-2-yl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM228164![]() (US10047073, 6 | US10047073, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC US Patent | Assay Description The Class I HDAC activity of Class IIa Histone Deacetylase (HDAC) inhibitors was quantified by measuring the cellular histone deacetylase enzymatic a... | US Patent US10047073 (2018) BindingDB Entry DOI: 10.7270/Q2PG1TQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597496![]() (CHEMBL5206259) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50552909![]() (CHEMBL4754665) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597489![]() (CHEMBL5208605) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597490![]() (CHEMBL5199904) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243152![]() (D1: N-((R)-1-((abs)-3- (Difluoromethoxy)piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597473![]() (CHEMBL5181094) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50506921![]() (CHEMBL4459800) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243193![]() (D1: N-((R)-1-((abs-1,5-cis)-6- Azabicyclo[3.2.0]he...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243192![]() (N-((2R)-1-(3-Azabicyclo[3.2.0]heptan- 3-yl)propan-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597492![]() (CHEMBL5186165) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243189![]() ((R)-N-(1-(3,4-dihydro-2,7-naphthyridin- 2(1H)-yl)p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597494![]() (CHEMBL5188032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597485![]() (CHEMBL5183751) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597487![]() (CHEMBL5169406) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243183![]() (N-((R)-1-(3-Azabicyclo[3.2.1]octan-3- yl)propan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243180![]() ((R)-N-(1-(5-Azaspiro[2.4]heptan-5- yl)propan-2-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM228164![]() (US10047073, 6 | US10047073, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC US Patent | Assay Description The Class I HDAC activity of Class IIa Histone Deacetylase (HDAC) inhibitors was quantified by measuring the cellular histone deacetylase enzymatic a... | US Patent US10047073 (2018) BindingDB Entry DOI: 10.7270/Q2PG1TQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243091![]() (N-((2R)-1-(3-Azabicyclo[3.1.0]hexan-3- yl)propan-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243202![]() ((2S)-1-((R)-2-(3-Fluoro-4-(5- (trifluoromethyl)-1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50597475![]() (CHEMBL5200987) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00474 BindingDB Entry DOI: 10.7270/Q2P2735N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [648-1032] (Homo sapiens (Human)) | BDBM243121![]() ((R)-N-(1-(3,4-Dihydroisoquinolin- 2(1H)-yl)propan-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293916![]() ((S)-1-(3,4-Difluoro-2- methylphenyl)-N- hydroxy-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI Foundation, Inc. US Patent | Assay Description 2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr... | US Patent US9617259 (2017) BindingDB Entry DOI: 10.7270/Q2DN4743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM243178![]() ((R)-N-(1-(Azepan-1-yl)propan-2-yl)-4- (5-(trifluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM162840![]() (US9056843, 131) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50552915![]() (CHEMBL4798111) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM162839![]() (US9056843, 130) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC4 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM162846![]() (US9056843, 137) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC5 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 7 (Homo sapiens (Human)) | BDBM162846![]() (US9056843, 137) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC7 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 9 (Homo sapiens (Human)) | BDBM162846![]() (US9056843, 137) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HDAC9 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50552909![]() (CHEMBL4754665) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50552912![]() (CHEMBL4760047) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Class 2A HDAC4 in human Jurkat E6.1 cells using Boc-Lys-(TFA)-AMC as substrate by fluorogenic assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00532 BindingDB Entry DOI: 10.7270/Q2474FHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50161830![]() (CHEMBL3793439) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
BioFocus Curated by ChEMBL | Assay Description Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrate | ACS Med Chem Lett 7: 34-9 (2016) Article DOI: 10.1021/acsmedchemlett.5b00302 BindingDB Entry DOI: 10.7270/Q22Z17DJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293880![]() ((S)-1-(3-Fluoro-2- methylphenyl)-3-(5- fluoropyrid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293886![]() ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(qui...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293895![]() ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(imi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293899![]() ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(6- ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293900![]() ((S)-3-(5-Chloro-6- methylpyridin-3-yl)-1-(3- fluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293911![]() ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(2- ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293912![]() ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(1-m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair |
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