Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50081081 (6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Groton Curated by ChEMBL | Assay Description Binding affinity of compound to human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 9: 2569-72 (1999) BindingDB Entry DOI: 10.7270/Q2BC3XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50081081 (6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Groton Curated by ChEMBL | Assay Description Binding ability of compound to human Dopamine receptor D2 | Bioorg Med Chem Lett 9: 2569-72 (1999) BindingDB Entry DOI: 10.7270/Q2BC3XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50081081 (6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Groton Curated by ChEMBL | Assay Description Binding affinity of compound to human 5-hydroxytryptamine 2A receptor | Bioorg Med Chem Lett 9: 2569-72 (1999) BindingDB Entry DOI: 10.7270/Q2BC3XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50081082 (2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Groton Curated by ChEMBL | Assay Description Binding affinity of compound to m2 muscarinic receptor | Bioorg Med Chem Lett 9: 2569-72 (1999) BindingDB Entry DOI: 10.7270/Q2BC3XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50081082 (2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Groton Curated by ChEMBL | Assay Description Binding ability of compound to m4 muscarinic receptor | Bioorg Med Chem Lett 9: 2569-72 (1999) BindingDB Entry DOI: 10.7270/Q2BC3XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033236 (8,9-Dichloro-2-methyl-5-[4-(2-methyl-imidazo[4,5-c...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033242 (3-Cyclohexyl-6-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033257 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033238 (3-(4-Chloro-phenyl)-1,8-dimethyl-5-[4-(2-methyl-im...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033240 (1-Methyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033264 (3-Cyclohexyl-1,8-dimethyl-5-[4-(2-methyl-imidazo[4...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033260 (3-Isobutoxymethyl-1,8-dimethyl-5-[4-(2-methyl-imid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033234 (1,3-Dimethyl-7-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033233 (8,9-Dichloro-1-methyl-5-[4-(2-methyl-imidazo[4,5-c...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033249 (5,7,9-Trimethyl-2-[4-(2-methyl-imidazo[4,5-c]pyrid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033229 (8,9-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033245 (8-Bromo-5-methyl-2-[4-(2-methyl-imidazo[4,5-c]pyri...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033255 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033232 (8,9-Dichloro-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033263 (8,9-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033251 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033231 (1,8,9-Trimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyrid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033246 (5-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033243 (1-Methyl-7-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033230 (5-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033268 (5-Methyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033241 (3-Isopropyl-1,8-dimethyl-5-[4-(2-methyl-imidazo[4,...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033254 (8-Bromo-2-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl)...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033235 (7-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-yl)-phenyl]...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033239 (8-Bromo-1-methyl-4-[4-(2-methyl-imidazo[4,5-c]pyri...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033266 (1,3,4-Trimethyl-7-[4-(2-methyl-imidazo[4,5-c]pyrid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033237 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033267 (8-Bromo-4-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl)...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Misshapen-like kinase 1 (Homo sapiens (Human)) | BDBM50361467 (CHEMBL1938400) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MINK | J Med Chem 54: 7797-814 (2011) Article DOI: 10.1021/jm200677b BindingDB Entry DOI: 10.7270/Q2HX1D4Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033253 (3-(2-Methoxy-ethoxymethyl)-1,8-dimethyl-5-[4-(2-me...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033258 (7,9-Dimethyl-2-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033248 (8,9-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033261 (1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033256 (3-Hydroxymethyl-1,8-dimethyl-5-[4-(2-methyl-imidaz...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (RAT-Rattus norvegicus) | BDBM50072197 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4. | Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human)) | BDBM50072197 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Evaluated for its ability to inhibit PDE3. | Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033228 (1,3,8-Trimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyrid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033227 (7,9-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50072197 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Evaluated for its ability to inhibit PDE4D. | Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 11 (Homo sapiens (Human)) | BDBM50361467 (CHEMBL1938400) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of p38beta MAPK | J Med Chem 54: 7797-814 (2011) Article DOI: 10.1021/jm200677b BindingDB Entry DOI: 10.7270/Q2HX1D4Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (RAT) | BDBM50072197 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Evaluated for its ability to inhibit PDE4B. | Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033262 (1,3-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50072197 (2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Evaluated for its ability to inhibit PDE4A. | Bioorg Med Chem Lett 8: 2891-6 (1999) BindingDB Entry DOI: 10.7270/Q2PG1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50033247 (1,7,9-Trimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyrid...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit platelets | J Med Chem 38: 3524-35 (1995) BindingDB Entry DOI: 10.7270/Q2JS9R2X | |||||||||||
More data for this Ligand-Target Pair |
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