Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279431 (3-(4-Chloro-phenyl)-2-[2-(4-chloro-phenylamino)-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279429 (3-(4-Chloro-phenyl)-2-(4-methyl-2-methylamino-thia...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279429 (3-(4-Chloro-phenyl)-2-(4-methyl-2-methylamino-thia...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B.V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 (unknown origin) expressed in HEK293 cells assessed as inhibition of TNFalpha-induced transcriptional activation treated 24 hrs bef... | Eur J Med Chem 44: 2184-9 (2009) Article DOI: 10.1016/j.ejmech.2008.10.031 BindingDB Entry DOI: 10.7270/Q25X28SV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279431 (3-(4-Chloro-phenyl)-2-[2-(4-chloro-phenylamino)-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B.V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 (unknown origin) expressed in HEK293 cells assessed as inhibition of TNFalpha-induced transcriptional activation treated 24 hrs bef... | Eur J Med Chem 44: 2184-9 (2009) Article DOI: 10.1016/j.ejmech.2008.10.031 BindingDB Entry DOI: 10.7270/Q25X28SV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50326123 (3-(4-Chloro-phenyl)-2-[2-(4-chloro-phenylamino)-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50315777 (3-(4-Acetyl-phenyl)-2-(5-morpholin-4-yl-4-pyridin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP-1 expressed in HEK293 cells assessed as PMA-stimulated transcriptional activation treated 24 hrs before PMA challenge measured after... | Bioorg Med Chem 18: 2796-808 (2010) Article DOI: 10.1016/j.bmc.2010.01.007 BindingDB Entry DOI: 10.7270/Q2S182NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279698 (2-(4-Methyl-2-methylamino-thiazol-5-yl)-3-o-tolyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B.V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 (unknown origin) expressed in HEK293 cells assessed as inhibition of TNFalpha-induced transcriptional activation treated 24 hrs bef... | Eur J Med Chem 44: 2184-9 (2009) Article DOI: 10.1016/j.ejmech.2008.10.031 BindingDB Entry DOI: 10.7270/Q25X28SV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50279699 (2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B.V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 (unknown origin) expressed in HEK293 cells assessed as inhibition of TNFalpha-induced transcriptional activation treated 24 hrs bef... | Eur J Med Chem 44: 2184-9 (2009) Article DOI: 10.1016/j.ejmech.2008.10.031 BindingDB Entry DOI: 10.7270/Q25X28SV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50326119 (CHEMBL1242070 | [5-(4-Oxo-3-phenyl-3,4-dihydro-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50326121 (CHEMBL1242520 | {5-[3-(4-Chloro-phenyl)-4-oxo-3,4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50326120 (2-[2-(4-Chloro-phenylamino)-4-phenyl-thiazol-5-yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50326122 (3-(4-Chloro-phenyl)-2-(2-methylamino-4-phenyl-thia...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL | Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l... | Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW | |||||||||||
More data for this Ligand-Target Pair |