Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucagon receptor (Homo sapiens (Human)) | BDBM50244265 (CHEMBL480113 | trans-4-((4-tert-butylcyclohexyl)(1...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244236 (CHEMBL500315 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244238 (CHEMBL499372 | trans-4-(((5-(benzyloxy)-1-methyl-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358368 (CHEMBL1922834) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358360 (CHEMBL1922708) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199486 (3-(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(tri...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393776 (CHEMBL2159349) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244235 (CHEMBL480692 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244199 (CHEMBL458145 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244234 (CHEMBL518939 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244237 (CHEMBL448921 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358373 (CHEMBL1922839) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393781 (CHEMBL2159337) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358366 (CHEMBL1922714) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358370 (CHEMBL1922836) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50334486 (CHEMBL1643951 | trans-4-((1-(4-tert-butylcyclohexy...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 21: 76-81 (2010) Article DOI: 10.1016/j.bmcl.2010.11.074 BindingDB Entry DOI: 10.7270/Q2R211PW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50171818 (4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorometho...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagon | Bioorg Med Chem Lett 15: 4564-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.101 BindingDB Entry DOI: 10.7270/Q26T0M5F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244122 (CHEMBL459457 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244233 (CHEMBL513067 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358346 (CHEMBL1922696) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244264 (CHEMBL471979 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244235 (CHEMBL480692 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulation | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393780 (CHEMBL2159353) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199498 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(4-(tri...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199498 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(4-(tri...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393786 (CHEMBL2159342) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358362 (CHEMBL1922710) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393785 (CHEMBL2159341) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199493 (1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(triflu...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199495 (1-(5-((2H-tetrazol-5-yl)carbamoyl)-2,3-dihydro-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393775 (CHEMBL2159348) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393776 (CHEMBL2159349) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ... | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358810 (CHEMBL1922938) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by scintillation proximity assay | Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50199495 (1-(5-((2H-tetrazol-5-yl)carbamoyl)-2,3-dihydro-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation | Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244266 (CHEMBL472154 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244300 (CHEMBL470955 | trans-4-(((4-tert-butylcyclohexyl)(...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358374 (CHEMBL1922840) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Homo sapiens (Human)) | BDBM50019355 (1-(3,4,5-Trimethoxy-benzyl)-1,2,3,4-tetrahydro-iso...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against human beta1 adrenergic receptor (AR) | Bioorg Med Chem Lett 10: 2283-6 (2001) BindingDB Entry DOI: 10.7270/Q2F47NCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50019355 (1-(3,4,5-Trimethoxy-benzyl)-1,2,3,4-tetrahydro-iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against CHO cells expressing the cloned human beta2 adrenergic receptor (AR) in the presence of [1... | Bioorg Med Chem Lett 10: 2283-6 (2001) BindingDB Entry DOI: 10.7270/Q2F47NCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50360601 (CHEMBL1933349 | MK-0893) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-1 adrenergic receptor (Homo sapiens (Human)) | BDBM50070125 (CHEMBL276659 | N-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]-iodocyanopindolol as the radioligand | Bioorg Med Chem Lett 8: 1101-6 (1999) BindingDB Entry DOI: 10.7270/Q2VM4BDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393778 (CHEMBL2159351) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244298 (CHEMBL472325 | trans-4-(((5-bromo-1-methyl-1H-benz...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358375 (CHEMBL1922841) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50244238 (CHEMBL499372 | trans-4-(((5-(benzyloxy)-1-methyl-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulation | Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358371 (CHEMBL1922837) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50358367 (CHEMBL1922715) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting | Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393788 (CHEMBL2159347) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393784 (CHEMBL2159340) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM50393785 (CHEMBL2159341) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ... | J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 1581 total ) | Next | Last >> |