Compile Data Set for Download or QSAR

Found 76 hits with Last Name = 'hong' and Initial = 'sg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331029 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C24H27FN4O4/c1-14-21(11-18-17-10-15(25)2-3-19(17)27-23(18)31)26-20-4-5-29(24(32)22(14)20)13-16(30)12-28-6-8-33-9-7-28/h2-3,10-11,16,26,30H,4-9,12-13H2,1H3,(H,27,31)/b18-11-/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331031 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C24H27FN4O3/c1-15-21(14-18-17-13-16(25)4-5-19(17)27-23(18)30)26-20-3-2-6-29(24(31)22(15)20)8-7-28-9-11-32-12-10-28/h4-5,13-14,26H,2-3,6-12H2,1H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331026 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CN(C)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C21H23FN4O2/c1-12-18(11-15-14-10-13(22)4-5-16(14)24-20(15)27)23-17-6-7-26(9-8-25(2)3)21(28)19(12)17/h4-5,10-11,23H,6-9H2,1-3H3,(H,24,27)/b15-11-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331028 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O3/c1-14-20(13-17-16-12-15(24)2-3-18(16)26-22(17)29)25-19-4-5-28(23(30)21(14)19)7-6-27-8-10-31-11-9-27/h2-3,12-13,25H,4-11H2,1H3,(H,26,29)/b17-13-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331029 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C24H27FN4O4/c1-14-21(11-18-17-10-15(25)2-3-19(17)27-23(18)31)26-20-4-5-29(24(32)22(14)20)13-16(30)12-28-6-8-33-9-7-28/h2-3,10-11,16,26,30H,4-9,12-13H2,1H3,(H,27,31)/b18-11-/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331023 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B method				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331023 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331024 ((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Cl)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27ClN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331026 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CN(C)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C21H23FN4O2/c1-12-18(11-15-14-10-13(22)4-5-16(14)24-20(15)27)23-17-6-7-26(9-8-25(2)3)21(28)19(12)17/h4-5,10-11,23H,6-9H2,1-3H3,(H,24,27)/b15-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331025 ((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Br)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27BrN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331027 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O2/c1-14-20(13-17-16-12-15(24)4-5-18(16)26-22(17)29)25-19-6-9-28(23(30)21(14)19)11-10-27-7-2-3-8-27/h4-5,12-13,25H,2-3,6-11H2,1H3,(H,26,29)/b17-13-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331026 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CN(C)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C21H23FN4O2/c1-12-18(11-15-14-10-13(22)4-5-16(14)24-20(15)27)23-17-6-7-26(9-8-25(2)3)21(28)19(12)17/h4-5,10-11,23H,6-9H2,1-3H3,(H,24,27)/b15-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331025 ((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Br)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27BrN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331023 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331024 ((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Cl)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27ClN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331031 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C24H27FN4O3/c1-15-21(14-18-17-13-16(25)4-5-19(17)27-23(18)30)26-20-3-2-6-29(24(31)22(15)20)8-7-28-9-11-32-12-10-28/h4-5,13-14,26H,2-3,6-12H2,1H3,(H,27,30)/b18-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331027 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O2/c1-14-20(13-17-16-12-15(24)4-5-18(16)26-22(17)29)25-19-6-9-28(23(30)21(14)19)11-10-27-7-2-3-8-27/h4-5,12-13,25H,2-3,6-11H2,1H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331030 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C24H29FN4O2/c1-4-28(5-2)11-12-29-10-6-7-20-22(24(29)31)15(3)21(26-20)14-18-17-13-16(25)8-9-19(17)27-23(18)30/h8-9,13-14,26H,4-7,10-12H2,1-3H3,(H,27,30)/b18-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331023 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331031 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C24H27FN4O3/c1-15-21(14-18-17-13-16(25)4-5-19(17)27-23(18)30)26-20-3-2-6-29(24(31)22(15)20)8-7-28-9-11-32-12-10-28/h4-5,13-14,26H,2-3,6-12H2,1H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331029 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C24H27FN4O4/c1-14-21(11-18-17-10-15(25)2-3-19(17)27-23(18)31)26-20-4-5-29(24(32)22(14)20)13-16(30)12-28-6-8-33-9-7-28/h2-3,10-11,16,26,30H,4-9,12-13H2,1H3,(H,27,31)/b18-11-/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331032 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C25H29FN4O4/c1-15-22(12-19-18-11-16(26)4-5-20(18)28-24(19)32)27-21-3-2-6-30(25(33)23(15)21)14-17(31)13-29-7-9-34-10-8-29/h4-5,11-12,17,27,31H,2-3,6-10,13-14H2,1H3,(H,28,32)/b19-12-/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331027 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O2/c1-14-20(13-17-16-12-15(24)4-5-18(16)26-22(17)29)25-19-6-9-28(23(30)21(14)19)11-10-27-7-2-3-8-27/h4-5,12-13,25H,2-3,6-11H2,1H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50331033 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C25H31FN4O2/c1-4-29(5-2)12-13-30-11-7-6-8-21-23(25(30)32)16(3)22(27-21)15-19-18-14-17(26)9-10-20(18)28-24(19)31/h9-10,14-15,27H,4-8,11-13H2,1-3H3,(H,28,31)/b19-15-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320285 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) Show SMILES CN(C)C(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C17H27N5O2/c1-20(2)17(24)21-10-12-6-14(7-13(12)11-21)19-9-16(23)22-5-3-4-15(22)8-18/h12-15,19H,3-7,9-11H2,1-2H3/t12-,13+,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N |r,TLB:9:8:6:3.2.4,4:3:10:7.6.5,4:5:10:3.2.9,THB:9:3:6:10.7.8,11:8:6:3.2.4| Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331030 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C24H29FN4O2/c1-4-28(5-2)11-12-29-10-6-7-20-22(24(29)31)15(3)21(26-20)14-18-17-13-16(25)8-9-19(17)27-23(18)30/h8-9,13-14,26H,4-7,10-12H2,1-3H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331024 ((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Cl)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27ClN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331028 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O3/c1-14-20(13-17-16-12-15(24)2-3-18(16)26-22(17)29)25-19-4-5-28(23(30)21(14)19)7-6-27-8-10-31-11-9-27/h2-3,12-13,25H,4-11H2,1H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331032 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C25H29FN4O4/c1-15-22(12-19-18-11-16(26)4-5-20(18)28-24(19)32)27-21-3-2-6-30(25(33)23(15)21)14-17(31)13-29-7-9-34-10-8-29/h4-5,11-12,17,27,31H,2-3,6-10,13-14H2,1H3,(H,28,32)/b19-12-/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320294 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) Show SMILES CN(C)C(=O)N1C[C@H]2C[C@@](C)(C[C@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C18H29N5O2/c1-18(20-10-16(24)23-6-4-5-15(23)9-19)7-13-11-22(12-14(13)8-18)17(25)21(2)3/h13-15,20H,4-8,10-12H2,1-3H3/t13-,14+,15-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320293 ((3aR,5alpha,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)...) Show SMILES CN(C)C(=O)N1C[C@H]2C[C@](C)(C[C@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C18H29N5O2/c1-18(20-10-16(24)23-6-4-5-15(23)9-19)7-13-11-22(12-14(13)8-18)17(25)21(2)3/h13-15,20H,4-8,10-12H2,1-3H3/t13-,14+,15-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331033 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C25H31FN4O2/c1-4-29(5-2)12-13-30-11-7-6-8-21-23(25(30)32)16(3)22(27-21)15-19-18-14-17(26)9-10-20(18)28-24(19)31/h9-10,14-15,27H,4-8,11-13H2,1-3H3,(H,28,31)/b19-15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320291 ((S)-1-(2-((3aR,5beta,6aS)-2-(2-hydroxyacetyl)octah...) Show SMILES OCC(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H24N4O3/c17-6-14-2-1-3-20(14)15(22)7-18-13-4-11-8-19(16(23)10-21)9-12(11)5-13/h11-14,18,21H,1-5,7-10H2/t11-,12+,13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331030 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C24H29FN4O2/c1-4-28(5-2)11-12-29-10-6-7-20-22(24(29)31)15(3)21(26-20)14-18-17-13-16(25)8-9-19(17)27-23(18)30/h8-9,13-14,26H,4-7,10-12H2,1-3H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331025 ((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...) Show SMILES CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(Br)cc34)c(C)c2C1=O Show InChI InChI=1S/C23H27BrN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331029 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C24H27FN4O4/c1-14-21(11-18-17-10-15(25)2-3-19(17)27-23(18)31)26-20-4-5-29(24(32)22(14)20)13-16(30)12-28-6-8-33-9-7-28/h2-3,10-11,16,26,30H,4-9,12-13H2,1H3,(H,27,31)/b18-11-/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B method				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320290 ((3aR,5beta,6aS)-methyl 5-(2-((S)-2-cyanopyrrolidin...) Show SMILES COC(=O)N1C[C@@H]2C[C@@H](C[C@@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H24N4O3/c1-23-16(22)19-9-11-5-13(6-12(11)10-19)18-8-15(21)20-4-2-3-14(20)7-17/h11-14,18H,2-6,8-10H2,1H3/t11-,12+,13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331028 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C23H25FN4O3/c1-14-20(13-17-16-12-15(24)2-3-18(16)26-22(17)29)25-19-4-5-28(23(30)21(14)19)7-6-27-8-10-31-11-9-27/h2-3,12-13,25H,4-11H2,1H3,(H,26,29)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331032 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C25H29FN4O4/c1-15-22(12-19-18-11-16(26)4-5-20(18)28-24(19)32)27-21-3-2-6-30(25(33)23(15)21)14-17(31)13-29-7-9-34-10-8-29/h4-5,11-12,17,27,31H,2-3,6-10,13-14H2,1H3,(H,28,32)/b19-12-/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B method				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331032 ((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(C[C@H](O)CN3CCOCC3)C(=O)c12 |r| Show InChI InChI=1S/C25H29FN4O4/c1-15-22(12-19-18-11-16(26)4-5-20(18)28-24(19)32)27-21-3-2-6-30(25(33)23(15)21)14-17(31)13-29-7-9-34-10-8-29/h4-5,11-12,17,27,31H,2-3,6-10,13-14H2,1H3,(H,28,32)/b19-12-/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of c-Kit after 30 mins by ELISA				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331031 ((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...) Show SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(CCN3CCOCC3)C(=O)c12 Show InChI InChI=1S/C24H27FN4O3/c1-15-21(14-18-17-13-16(25)4-5-19(17)27-23(18)30)26-20-3-2-6-29(24(31)22(15)20)8-7-28-9-11-32-12-10-28/h4-5,13-14,26H,2-3,6-12H2,1H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B method				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320287 ((3aR,5beta,6aS)-N-butyl-5-(2-((S)-2-cyanopyrrolidi...) Show SMILES O=C(CN[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)N1CCCC1)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C19H29N5O2/c20-10-17-4-3-7-24(17)18(25)11-21-16-8-14-12-23(13-15(14)9-16)19(26)22-5-1-2-6-22/h14-17,21H,1-9,11-13H2/t14-,15+,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320289 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) Show SMILES O=C(CN[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)N1CCOCC1)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C19H29N5O3/c20-10-17-2-1-3-24(17)18(25)11-21-16-8-14-12-23(13-15(14)9-16)19(26)22-4-6-27-7-5-22/h14-17,21H,1-9,11-13H2/t14-,15+,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320288 ((3aR,5beta,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)-...) Show SMILES O=C(CN[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)N1CCCCC1)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H31N5O2/c21-11-18-5-4-8-25(18)19(26)12-22-17-9-15-13-24(14-16(15)10-17)20(27)23-6-2-1-3-7-23/h15-18,22H,1-10,12-14H2/t15-,16+,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50320292 ((3aR,5alpha,6aS)-5-(2-((S)-2-cyanopyrrolidin-1-yl)...) Show SMILES CN(C)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C17H27N5O2/c1-20(2)17(24)21-10-12-6-14(7-13(12)11-21)19-9-16(23)22-5-3-4-15(22)8-18/h12-15,19H,3-7,9-11H2,1-2H3/t12-,13+,14+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 20: 3565-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.120 BindingDB Entry DOI: 10.7270/Q2P55NQQ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331030 ((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...) Show SMILES CCN(CC)CCN1CCCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O Show InChI InChI=1S/C24H29FN4O2/c1-4-28(5-2)11-12-29-10-6-7-20-22(24(29)31)15(3)21(26-20)14-18-17-13-16(25)8-9-19(17)27-23(18)30/h8-9,13-14,26H,4-7,10-12H2,1-3H3,(H,27,30)/b18-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Hengrui Pharmaceuticals Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B method				J Med Chem 53: 8140-9 (2010) Article DOI: 10.1021/jm101036c BindingDB Entry DOI: 10.7270/Q2BV7GWF
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 76 total )  |  Next  |  Last  >>

Jump to: