Found 114 hits with Last Name = 'humphries' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317140
(5-(2-(diethylamino)ethylamino)-7-hydroxy-8,9-dimet...)Show SMILES CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1c(O)c(OC)c(OC)cc31 Show InChI InChI=1S/C22H26N4O4/c1-5-25(6-2)10-9-23-13-7-8-14-19-17(13)20(27)18-15(26(19)12-24-14)11-16(29-3)22(30-4)21(18)28/h7-8,11-12,23,28H,5-6,9-10H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008356
(5-(2-(diethylamino)ethylamino)-8-methoxy-1-methyl-...)Show SMILES CCN(CC)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(OC)ccc31 Show InChI InChI=1S/C22H26N4O2/c1-5-25(6-2)12-11-23-17-8-9-18-21-20(17)22(27)16-13-15(28-4)7-10-19(16)26(21)14(3)24-18/h7-10,13,23H,5-6,11-12H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354527
(CHEMBL1836819)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3ncn2c13 Show InChI InChI=1S/C19H20N4O3/c1-23(2,25)9-8-20-14-5-6-15-18-17(14)19(24)13-10-12(26-3)4-7-16(13)22(18)11-21-15/h4-7,10-11,20H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008344
(5-(2-(diethylamino)ethylamino)-8-hydroxy-1-methyl-...)Show SMILES CCN(CC)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(O)ccc31 Show InChI InChI=1S/C21H24N4O2/c1-4-24(5-2)11-10-22-16-7-8-17-20-19(16)21(27)15-12-14(26)6-9-18(15)25(20)13(3)23-17/h6-9,12,22,26H,4-5,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317138
(5-(2-(diethylamino)ethylamino)-7,10-dimethoxy-6H-i...)Show SMILES CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1c(OC)ccc(OC)c31 Show InChI InChI=1S/C22H26N4O3/c1-5-25(6-2)12-11-23-14-7-8-15-20-18(14)22(27)19-16(28-3)9-10-17(29-4)21(19)26(20)13-24-15/h7-10,13,23H,5-6,11-12H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317139
(5-(2-(diethylamino)ethylamino)-7-hydroxy-10-methox...)Show SMILES CCN(CC)CCNc1ccc2ncn3c2c1c(=O)c1c(O)ccc(OC)c31 Show InChI InChI=1S/C21H24N4O3/c1-4-24(5-2)11-10-22-13-6-7-14-19-17(13)21(27)18-15(26)8-9-16(28-3)20(18)25(19)12-23-14/h6-9,12,22,26H,4-5,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354535
(CHEMBL1836822)Show SMILES C[N+](C)([O-])CCNc1ccc2ncn3c2c1c(=O)c1cc(O)ccc31 Show InChI InChI=1S/C18H18N4O3/c1-22(2,25)8-7-19-13-4-5-14-17-16(13)18(24)12-9-11(23)3-6-15(12)21(17)10-20-14/h3-6,9-10,19,23H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354530
(CHEMBL340884)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCCN(C)C)ccc3nc(C)n2c13 Show InChI InChI=1S/C20H22N4O2/c1-12-22-16-7-6-15(21-9-10-23(2)3)18-19(16)24(12)17-8-5-13(26-4)11-14(17)20(18)25/h5-8,11,21H,9-10H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354539
(CHEMBL1836826)Show SMILES Cc1nc2ccc(NCC[N+](C)(C)[O-])c3c2n1c1ccc(Br)cc1c3=O Show InChI InChI=1S/C19H19BrN4O2/c1-11-22-15-6-5-14(21-8-9-24(2,3)26)17-18(15)23(11)16-7-4-12(20)10-13(16)19(17)25/h4-7,10,21H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008352
(5-(2-(dimethylamino)ethylamino)-8-hydroxy-1-methyl...)Show InChI InChI=1S/C19H20N4O2/c1-11-21-15-6-5-14(20-8-9-22(2)3)17-18(15)23(11)16-7-4-12(24)10-13(16)19(17)25/h4-7,10,20,24H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008344
(5-(2-(diethylamino)ethylamino)-8-hydroxy-1-methyl-...)Show SMILES CCN(CC)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(O)ccc31 Show InChI InChI=1S/C21H24N4O2/c1-4-24(5-2)11-10-22-16-7-8-17-20-19(16)21(27)15-12-14(26)6-9-18(15)25(20)13(3)23-17/h6-9,12,22,26H,4-5,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354538
(CHEMBL1836825)Show SMILES Cc1nc2ccc(NCC[N+](C)(C)[O-])c3c2n1c1ccccc1c3=O Show InChI InChI=1S/C19H20N4O2/c1-12-21-15-9-8-14(20-10-11-23(2,3)25)17-18(15)22(12)16-7-5-4-6-13(16)19(17)24/h4-9,20H,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354528
(CHEMBL125750)Show InChI InChI=1S/C19H20N4O2/c1-22(2)9-8-20-14-5-6-15-18-17(14)19(24)13-10-12(25-3)4-7-16(13)23(18)11-21-15/h4-7,10-11,20H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354536
(CHEMBL1836823)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3nc(C)n2c13 Show InChI InChI=1S/C20H22N4O3/c1-12-22-16-7-6-15(21-9-10-24(2,3)26)18-19(16)23(12)17-8-5-13(27-4)11-14(17)20(18)25/h5-8,11,21H,9-10H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354532
(CHEMBL1836818)Show SMILES CN(C)CCNc1ccc2nc(C)n3c2c1c(=O)c1cc(Br)ccc31 Show InChI InChI=1S/C19H19BrN4O/c1-11-22-15-6-5-14(21-8-9-23(2)3)17-18(15)24(11)16-7-4-12(20)10-13(16)19(17)25/h4-7,10,21H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354531
(CHEMBL1836817)Show InChI InChI=1S/C19H19FN4O/c1-11-22-15-6-5-14(21-8-9-23(2)3)17-18(15)24(11)16-7-4-12(20)10-13(16)19(17)25/h4-7,10,21H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM83846
(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)Show InChI InChI=1S/C18H18N4O2.ClH/c1-21(2)8-7-19-13-4-5-14-17-16(13)18(24)12-9-11(23)3-6-15(12)22(17)10-20-14;/h3-6,9-10,19,23H,7-8H2,1-2H3;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317134
(5-(2-(dimethylamino)ethylamino)-1-methyl-6H-imidaz...)Show InChI InChI=1S/C19H20N4O/c1-12-21-15-9-8-14(20-10-11-22(2)3)17-18(15)23(12)16-7-5-4-6-13(16)19(17)24/h4-9,20H,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008352
(5-(2-(dimethylamino)ethylamino)-8-hydroxy-1-methyl...)Show InChI InChI=1S/C19H20N4O2/c1-11-21-15-6-5-14(20-8-9-22(2)3)17-18(15)23(11)16-7-4-12(24)10-13(16)19(17)25/h4-7,10,20,24H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309775
(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C18H18N4O/c1-11(2)9-10-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)22(17)21-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309777
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1ccccc31 Show InChI InChI=1S/C17H17N5O2/c1-22(2,24)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)21(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354534
(CHEMBL1836821)Show SMILES C[N+](C)([O-])CCNc1ccc2ncn3c2c1c(=O)c1ccccc31 Show InChI InChI=1S/C18H18N4O2/c1-22(2,24)10-9-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)21(17)11-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354529
(CHEMBL1836795)Show InChI InChI=1S/C18H17FN4O/c1-22(2)8-7-20-13-4-5-14-17-16(13)18(24)12-9-11(19)3-6-15(12)23(17)10-21-14/h3-6,9-10,20H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354537
(CHEMBL1836824)Show SMILES Cc1nc2ccc(NCC[N+](C)(C)[O-])c3c2n1c1ccc(F)cc1c3=O Show InChI InChI=1S/C19H19FN4O2/c1-11-22-15-6-5-14(21-8-9-24(2,3)26)17-18(15)23(11)16-7-4-12(20)10-13(16)19(17)25/h4-7,10,21H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354527
(CHEMBL1836819)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3ncn2c13 Show InChI InChI=1S/C19H20N4O3/c1-23(2,25)9-8-20-14-5-6-15-18-17(14)19(24)13-10-12(26-3)4-7-16(13)22(18)11-21-15/h4-7,10-11,20H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry in the presence of 2 uM BSA |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309779
(5-(4-methoxyphenylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C20H14N4O2/c1-26-13-8-6-12(7-9-13)21-15-10-11-16-19-18(15)20(25)14-4-2-3-5-17(14)24(19)23-22-16/h2-11,21H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309780
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3nnn2c13 Show InChI InChI=1S/C18H19N5O3/c1-23(2,25)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(26-3)4-7-15(12)22(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317137
(5-(2-(diethylamino)ethylamino)-10-methoxy-6H-imida...)Show InChI InChI=1S/C21H24N4O2/c1-4-24(5-2)12-11-22-15-9-10-16-20-18(15)21(26)14-7-6-8-17(27-3)19(14)25(20)13-23-16/h6-10,13,22H,4-5,11-12H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309771
(8-bromo-5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,...)Show InChI InChI=1S/C18H17BrN4O/c1-10(2)7-8-20-13-4-5-14-17-16(13)18(24)12-9-11(19)3-6-15(12)23(17)22-21-14/h3-6,9-10,20H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309766
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show InChI InChI=1S/C18H19N5O2/c1-22(2)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(25-3)4-7-15(12)23(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317133
(5-(2-(dimethylamino)ethylamino)-6H-imidazo[4,5,1-d...)Show InChI InChI=1S/C18H18N4O/c1-21(2)10-9-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)22(17)11-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309778
(5-(2-(dimethylamino)ethylamino)-8-bromo-6H-[1,2,3]...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1cc(Br)ccc31 Show InChI InChI=1S/C17H16BrN5O2/c1-23(2,25)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)22(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008347
(5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-imidaz...)Show InChI InChI=1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8,11-12,21,25H,3-4,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309774
(5-(3-hydroxypropylamino)-8-bromo-6H-[1,2,3]triazol...)Show InChI InChI=1S/C16H13BrN4O2/c17-9-2-5-13-10(8-9)16(23)14-11(18-6-1-7-22)3-4-12-15(14)21(13)20-19-12/h2-5,8,18,22H,1,6-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50008347
(5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-imidaz...)Show InChI InChI=1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8,11-12,21,25H,3-4,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309777
(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)Show SMILES C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1ccccc31 Show InChI InChI=1S/C17H17N5O2/c1-22(2,24)10-9-18-12-7-8-13-16-15(12)17(23)11-5-3-4-6-14(11)21(16)20-19-13/h3-8,18H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 167 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317136
(5-(3-(dimethylamino)propylamino)-6H-imidazo[4,5,1-...)Show InChI InChI=1S/C19H20N4O/c1-22(2)11-5-10-20-14-8-9-15-18-17(14)19(24)13-6-3-4-7-16(13)23(18)12-21-15/h3-4,6-9,12,20H,5,10-11H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309768
(5-(2-(dimethylamino)ethylamino)-8-fluoro-6H-[1,2,3...)Show InChI InChI=1S/C17H16FN5O/c1-22(2)8-7-19-12-4-5-13-16-15(12)17(24)11-9-10(18)3-6-14(11)23(16)21-20-13/h3-6,9,19H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309776
(5-(3-hydroxypropylamino)-6H-[1,2,3]triazolo[4,5,1-...)Show InChI InChI=1S/C16H14N4O2/c21-9-3-8-17-11-6-7-12-15-14(11)16(22)10-4-1-2-5-13(10)20(15)19-18-12/h1-2,4-7,17,21H,3,8-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 203 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50354533
(CHEMBL1836820)Show SMILES C[N+](C)([O-])CCNc1ccc2ncn3c2c1c(=O)c1cc(F)ccc31 Show InChI InChI=1S/C18H17FN4O2/c1-23(2,25)8-7-20-13-4-5-14-17-16(13)18(24)12-9-11(19)3-6-15(12)22(17)10-21-14/h3-6,9-10,20H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 205 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
J Med Chem 54: 6597-611 (2011)
Article DOI: 10.1021/jm200416e BindingDB Entry DOI: 10.7270/Q21Z44TH |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309773
(5-(3-hydroxypropylamino)-8-methoxy-6H-[1,2,3]triaz...)Show InChI InChI=1S/C17H16N4O3/c1-24-10-3-6-14-11(9-10)17(23)15-12(18-7-2-8-22)4-5-13-16(15)21(14)20-19-13/h3-6,9,18,22H,2,7-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM83846
(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)Show InChI InChI=1S/C18H18N4O2.ClH/c1-21(2)8-7-19-13-4-5-14-17-16(13)18(24)12-9-11(23)3-6-15(12)22(17)10-20-14;/h3-6,9-10,19,23H,7-8H2,1-2H3;1H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 296 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317134
(5-(2-(dimethylamino)ethylamino)-1-methyl-6H-imidaz...)Show InChI InChI=1S/C19H20N4O/c1-12-21-15-9-8-14(20-10-11-22(2)3)17-18(15)23(12)16-7-5-4-6-13(16)19(17)24/h4-9,20H,10-11H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 323 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50309780
(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3nnn2c13 Show InChI InChI=1S/C18H19N5O3/c1-23(2,25)9-8-19-13-5-6-14-17-16(13)18(24)12-10-11(26-3)4-7-15(12)22(17)21-20-14/h4-7,10,19H,8-9H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 328 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309772
(8-methoxy-5-(phenethylamino)-6H-[1,2,3]triazolo[4,...)Show SMILES COc1ccc2c(c1)c(=O)c1c(NCCc3ccccc3)ccc3nnn2c13 Show InChI InChI=1S/C22H18N4O2/c1-28-15-7-10-19-16(13-15)22(27)20-17(8-9-18-21(20)26(19)25-24-18)23-12-11-14-5-3-2-4-6-14/h2-10,13,23H,11-12H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
NAD(P)H dehydrogenase [quinone] 1
(Homo sapiens (Human)) | BDBM50332183
(2-(2-Fluorophenyl)-4-(2-naphthyl)-2,3-dihydro-1,5-...)Show SMILES Fc1ccccc1C1CC(=Nc2ccccc2S1)c1ccc2ccccc2c1 |c:10| Show InChI InChI=1S/C25H18FNS/c26-21-10-4-3-9-20(21)25-16-23(27-22-11-5-6-12-24(22)28-25)19-14-13-17-7-1-2-8-18(17)15-19/h1-15,25H,16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO1 |
Bioorg Med Chem Lett 20: 7331-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.070 BindingDB Entry DOI: 10.7270/Q2M32W16 |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50317132
(5-(2-(diethylamino)ethylamino)-6H-imidazo[4,5,1-de...)Show InChI InChI=1S/C20H22N4O/c1-3-23(4-2)12-11-21-15-9-10-16-19-18(15)20(25)14-7-5-6-8-17(14)24(19)13-22-16/h5-10,13,21H,3-4,11-12H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM50309775
(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)Show InChI InChI=1S/C18H18N4O/c1-11(2)9-10-19-13-7-8-14-17-16(13)18(23)12-5-3-4-6-15(12)22(17)21-20-14/h3-8,11,19H,9-10H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 by spectrophotometry |
Bioorg Med Chem 18: 696-706 (2010)
Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ribosyldihydronicotinamide dehydrogenase [quinone]
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
the University of Manchester and Manchester Cancer Research Center
Curated by ChEMBL
| Assay Description Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry |
Bioorg Med Chem Lett 20: 2832-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.051 BindingDB Entry DOI: 10.7270/Q2FB533K |
More data for this Ligand-Target Pair | 3D Structure (crystal) |