Compile Data Set for Download or QSAR

Found 813 hits with Last Name = 'potashman' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164488 (US9066954, 373) Show SMILES Fc1cc(F)cc(c1)-c1ccc2nnc(CNc3ccnc4cc(OCCn5cncn5)cnc34)n2n1 Show InChI InChI=1S/C24H18F2N10O/c25-16-7-15(8-17(26)9-16)19-1-2-22-32-33-23(36(22)34-19)12-29-20-3-4-28-21-10-18(11-30-24(20)21)37-6-5-35-14-27-13-31-35/h1-4,7-11,13-14H,5-6,12H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-57.5	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17689 (2-aminobenzimidazole, 14 | N-{4-chloro-3-[(4-methy...) Show SMILES COc1cc2nccc(Oc3ccc4nc(Nc5ccc(Cl)c(CN6CCN(C)CC6)c5)[nH]c4c3)c2cc1OC Show InChI InChI=1S/C30H31ClN6O3/c1-36-10-12-37(13-11-36)18-19-14-20(4-6-23(19)31)33-30-34-24-7-5-21(15-26(24)35-30)40-27-8-9-32-25-17-29(39-3)28(38-2)16-22(25)27/h4-9,14-17H,10-13,18H2,1-3H3,(H2,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	-54.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164473 (US9066954, 302) Show SMILES COc1ccc2c(OCc3nnc4c(F)cc(cn34)-c3cc(C)cs3)ccnc2c1 Show InChI InChI=1S/C22H17FN4O2S/c1-13-7-20(30-12-13)14-8-17(23)22-26-25-21(27(22)10-14)11-29-19-5-6-24-18-9-15(28-2)3-4-16(18)19/h3-10,12H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-54.7	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17703 (2-aminobenzoxazole, 28 | N-(4-chloro-3-{[(2S)-1-me...) Show SMILES COc1cc2ncnc(Oc3ccc4oc(Nc5ccc(Cl)c(OC[C@@H]6CCCN6C)c5)nc4c3)c2cc1OC |r| Show InChI InChI=1S/C29H28ClN5O5/c1-35-10-4-5-18(35)15-38-25-11-17(6-8-21(25)30)33-29-34-23-12-19(7-9-24(23)40-29)39-28-20-13-26(36-2)27(37-3)14-22(20)31-16-32-28/h6-9,11-14,16,18H,4-5,10,15H2,1-3H3,(H,33,34)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17705 (2-aminobenzoxazole, 30 | N-{4-chloro-3-[(4-methylp...) Show SMILES COc1cc2nccc(Oc3ccc4oc(Nc5ccc(Cl)c(CN6CCN(C)CC6)c5)nc4c3)c2cc1OC Show InChI InChI=1S/C30H30ClN5O4/c1-35-10-12-36(13-11-35)18-19-14-20(4-6-23(19)31)33-30-34-25-15-21(5-7-27(25)40-30)39-26-8-9-32-24-17-29(38-3)28(37-2)16-22(24)26/h4-9,14-17H,10-13,18H2,1-3H3,(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17704 (2-aminobenzoxazole, 29 | N-(4-chloro-3-{[(2S)-1-me...) Show SMILES COc1cc2nccc(Oc3ccc4oc(Nc5ccc(Cl)c(OC[C@@H]6CCCN6C)c5)nc4c3)c2cc1OC |r| Show InChI InChI=1S/C30H29ClN4O5/c1-35-12-4-5-19(35)17-38-27-13-18(6-8-22(27)31)33-30-34-24-14-20(7-9-26(24)40-30)39-25-10-11-32-23-16-29(37-3)28(36-2)15-21(23)25/h6-11,13-16,19H,4-5,12,17H2,1-3H3,(H,33,34)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164486 (US9066954, 336) Show SMILES Cc1csc(c1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H15N5S/c1-13-9-18(26-12-13)17-6-7-19-22-23-20(25(19)24-17)11-14-4-5-16-15(10-14)3-2-8-21-16/h2-10,12H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	-52.6	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164420 (US9066954, 55) Show SMILES COc1cnc2c(NCc3nnc4ncc(nn34)-c3ccccc3)ccnc2c1 Show InChI InChI=1S/C20H16N8O/c1-29-14-9-16-19(23-10-14)15(7-8-21-16)22-12-18-25-26-20-24-11-17(27-28(18)20)13-5-3-2-4-6-13/h2-11H,12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	-52.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17687 (2-aminobenzimidazole, 12 | N-(3-{[(2R)-1-methylpyr...) Show SMILES CN1CCC[C@@H]1COc1cc(Nc2nc3ccc(Oc4ccnc5ccccc45)cc3[nH]2)ccc1C(F)(F)F |r| Show InChI InChI=1S/C29H26F3N5O2/c1-37-14-4-5-19(37)17-38-27-15-18(8-10-22(27)29(30,31)32)34-28-35-24-11-9-20(16-25(24)36-28)39-26-12-13-33-23-7-3-2-6-21(23)26/h2-3,6-13,15-16,19H,4-5,14,17H2,1H3,(H2,34,35,36)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	1	-50.9	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164453 (US9066954, 176) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(C)cs3)ccnc2c1 Show InChI InChI=1S/C20H17N7OS/c1-12-7-17(29-11-12)14-3-4-18-24-25-19(27(18)26-14)10-22-15-5-6-21-16-8-13(28-2)9-23-20(15)16/h3-9,11H,10H2,1-2H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.20	-51.3	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17709 (2-aminobenzoxazole, 34 | N-(4-chloro-3-{[(2S)-1-me...) Show SMILES CN1CCC[C@H]1COc1cc(Nc2nc3cc(Oc4ccnc5[nH]ccc45)ccc3o2)ccc1Cl |r| Show InChI InChI=1S/C26H24ClN5O3/c1-32-12-2-3-17(32)15-33-24-13-16(4-6-20(24)27)30-26-31-21-14-18(5-7-23(21)35-26)34-22-9-11-29-25-19(22)8-10-28-25/h4-11,13-14,17H,2-3,12,15H2,1H3,(H,28,29)(H,30,31)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24483 (5-(3-{[(7-methoxyquinolin-4-yl)oxy]methyl}-[1,2,4]...) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3cc(C)ns3)ccnc2c1 Show InChI InChI=1S/C20H16N6O2S/c1-12-9-18(29-25-12)15-5-6-19-22-23-20(26(19)24-15)11-28-17-7-8-21-16-10-13(27-2)3-4-14(16)17/h3-10H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	US Patent	1.60	-50.5	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164424 (US9066954, 62) Show SMILES COc1cnc2c(OCc3cnc4ccc(nn34)-c3cc(F)c(F)c(F)c3)ccnc2c1 Show InChI InChI=1S/C22H14F3N5O2/c1-31-14-8-18-22(28-10-14)19(4-5-26-18)32-11-13-9-27-20-3-2-17(29-30(13)20)12-6-15(23)21(25)16(24)7-12/h2-10H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70	-50.4	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164434 (US9066954, 85) Show SMILES COc1ccc2c(OCc3nnc4c(F)cc(cn34)-c3cc(C)ns3)ccnc2c1 Show InChI InChI=1S/C21H16FN5O2S/c1-12-7-19(30-26-12)13-8-16(22)21-25-24-20(27(21)10-13)11-29-18-5-6-23-17-9-14(28-2)3-4-15(17)18/h3-10H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-50.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164475 (US9066954, 309) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3ccc4ncsc4c3)ccnc2c1 Show InChI InChI=1S/C22H16N8OS/c1-31-14-9-18-22(25-10-14)17(6-7-23-18)24-11-21-28-27-20-5-4-15(29-30(20)21)13-2-3-16-19(8-13)32-12-26-16/h2-10,12H,11H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	-50.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17684 (2-aminobenzimidazole, 9 | N-methyl-4-({2-[(3-{[(2R...) Show SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(c(OC[C@H]5CCCN5C)c4)C(F)(F)F)[nH]c3c2)ccn1 |r| Show InChI InChI=1S/C27H27F3N6O3/c1-31-25(37)23-14-19(9-10-32-23)39-18-6-8-21-22(13-18)35-26(34-21)33-16-5-7-20(27(28,29)30)24(12-16)38-15-17-4-3-11-36(17)2/h5-10,12-14,17H,3-4,11,15H2,1-2H3,(H,31,37)(H2,33,34,35)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	-49.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17688 (2-aminobenzimidazole, 13 | N-{4-chloro-3-[(4-methy...) Show SMILES CN1CCN(Cc2cc(Nc3nc4ccc(Oc5ccnc6ccccc56)cc4[nH]3)ccc2Cl)CC1 Show InChI InChI=1S/C28H27ClN6O/c1-34-12-14-35(15-13-34)18-19-16-20(6-8-23(19)29)31-28-32-25-9-7-21(17-26(25)33-28)36-27-10-11-30-24-5-3-2-4-22(24)27/h2-11,16-17H,12-15,18H2,1H3,(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2	-49.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17710 (2-aminobenzoxazole, 35 | N-{4-chloro-3-[(4-methylp...) Show SMILES CN1CCN(Cc2cc(Nc3nc4cc(Oc5ccnc6[nH]ccc56)ccc4o3)ccc2Cl)CC1 Show InChI InChI=1S/C26H25ClN6O2/c1-32-10-12-33(13-11-32)16-17-14-18(2-4-21(17)27)30-26-31-22-15-19(3-5-24(22)35-26)34-23-7-9-29-25-20(23)6-8-28-25/h2-9,14-15H,10-13,16H2,1H3,(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17713 (2-aminobenzoxazole, 38 | 7-chloro-N-{4-chloro-3-[(...) Show SMILES CN1CCN(Cc2cc(Nc3nc4cc(Oc5ccnc6ccccc56)cc(Cl)c4o3)ccc2Cl)CC1 Show InChI InChI=1S/C28H25Cl2N5O2/c1-34-10-12-35(13-11-34)17-18-14-19(6-7-22(18)29)32-28-33-25-16-20(15-23(30)27(25)37-28)36-26-8-9-31-24-5-3-2-4-21(24)26/h2-9,14-16H,10-13,17H2,1H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164430 (US9066954, 75) Show SMILES CNC(=O)c1ccc(s1)-c1ccc2nnc(COc3ccnc4cc(OC)ccc34)n2c1 Show InChI InChI=1S/C23H19N5O3S/c1-24-23(29)20-7-6-19(32-20)14-3-8-21-26-27-22(28(21)12-14)13-31-18-9-10-25-17-11-15(30-2)4-5-16(17)18/h3-12H,13H2,1-2H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	-49.7	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164435 (US9066954, 86) Show SMILES COc1ccc2c(OCc3nnc4c(F)cc(cn34)-c3cnc(C)s3)ccnc2c1 Show InChI InChI=1S/C21H16FN5O2S/c1-12-24-9-19(30-12)13-7-16(22)21-26-25-20(27(21)10-13)11-29-18-5-6-23-17-8-14(28-2)3-4-15(17)18/h3-10H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	-49.5	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164457 (US9066954, 202) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4NC(=O)CCc4c3)ccnc2c1 Show InChI InChI=1S/C25H20N6O3/c1-33-17-4-5-18-21(13-17)26-11-10-22(18)34-14-24-29-28-23-8-7-20(30-31(23)24)16-2-6-19-15(12-16)3-9-25(32)27-19/h2,4-8,10-13H,3,9,14H2,1H3,(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.40	-49.5	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164464 (US9066954, 232) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4OCCOc4c3)ccnc2c1 Show InChI InChI=1S/C24H19N5O4/c1-30-16-3-4-17-19(13-16)25-9-8-20(17)33-14-24-27-26-23-7-5-18(28-29(23)24)15-2-6-21-22(12-15)32-11-10-31-21/h2-9,12-13H,10-11,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.60	-49.3	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164441 (US9066954, 118) Show SMILES COc1cnc2ccc(cc2c1)[C@H](C)c1nnc2ccc(nn12)-c1ccccc1 |r| Show InChI InChI=1S/C23H19N5O/c1-15(17-8-9-20-18(12-17)13-19(29-2)14-24-20)23-26-25-22-11-10-21(27-28(22)23)16-6-4-3-5-7-16/h3-15H,1-2H3/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.60	-49.3	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50302903 (7-methoxy-N-((6-(3,4,5-trifluorophenyl)-[1,2,4]tri...) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(F)c(F)c(F)c3)ccnc2c1 Show InChI InChI=1S/C21H14F3N7O/c1-32-12-8-17-21(27-9-12)16(4-5-25-17)26-10-19-29-28-18-3-2-15(30-31(18)19)11-6-13(22)20(24)14(23)7-11/h2-9H,10H2,1H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	2.70	-49.2	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17697 (2-aminobenzoxazole, 22 | 4-({2-[(4-chloro-3-{[(2S)...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(OC[C@@H]5CCCN5C)c4)nc3c2)ccn1 |r| Show InChI InChI=1S/C26H26ClN5O4/c1-28-25(33)22-14-19(9-10-29-22)35-18-6-8-23-21(13-18)31-26(36-23)30-16-5-7-20(27)24(12-16)34-15-17-4-3-11-32(17)2/h5-10,12-14,17H,3-4,11,15H2,1-2H3,(H,28,33)(H,30,31)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	2.80	-48.3	4.60	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164469 (US9066954, 294) Show SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3ccc4NC(=O)Cc4c3)ccnc2c1 Show InChI InChI=1S/C25H19N5O3/c1-32-18-4-5-19-21(12-18)26-9-8-22(19)33-14-24-29-28-23-7-3-16(13-30(23)24)15-2-6-20-17(10-15)11-25(31)27-20/h2-10,12-13H,11,14H2,1H3,(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.80	-49.1	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164446 (US9066954, 141) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4OCCc4c3)ccnc2c1 Show InChI InChI=1S/C24H19N5O3/c1-30-17-3-4-18-20(13-17)25-10-8-22(18)32-14-24-27-26-23-7-5-19(28-29(23)24)15-2-6-21-16(12-15)9-11-31-21/h2-8,10,12-13H,9,11,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.90	-49.1	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17711 (2-aminobenzoxazole, 36 | 4-({2-[(4-chloro-3-{[(2S)...) Show SMILES CNC(=O)c1cc(Oc2cc(F)c3oc(Nc4ccc(Cl)c(OC[C@@H]5CCCN5C)c4)nc3c2)ccn1 |r| Show InChI InChI=1S/C26H25ClFN5O4/c1-29-25(34)22-12-17(7-8-30-22)36-18-11-20(28)24-21(13-18)32-26(37-24)31-15-5-6-19(27)23(10-15)35-14-16-4-3-9-33(16)2/h5-8,10-13,16H,3-4,9,14H2,1-2H3,(H,29,34)(H,31,32)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17701 (2-aminobenzoxazole, 26 | 4-[(2-{[4-chloro-3-(piper...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(OCC5CCNCC5)c4)nc3c2)ccn1 Show InChI InChI=1S/C26H26ClN5O4/c1-28-25(33)22-14-19(8-11-30-22)35-18-3-5-23-21(13-18)32-26(36-23)31-17-2-4-20(27)24(12-17)34-15-16-6-9-29-10-7-16/h2-5,8,11-14,16,29H,6-7,9-10,15H2,1H3,(H,28,33)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17702 (2-aminobenzoxazole, 27 | 4-({2-[(4-chloro-3-{[(2S)...) Show SMILES CN1CCC[C@H]1COc1cc(Nc2nc3cc(Oc4ccnc(c4)C(N)=O)ccc3o2)ccc1Cl |r| Show InChI InChI=1S/C25H24ClN5O4/c1-31-10-2-3-16(31)14-33-23-11-15(4-6-19(23)26)29-25-30-20-12-17(5-7-22(20)35-25)34-18-8-9-28-21(13-18)24(27)32/h4-9,11-13,16H,2-3,10,14H2,1H3,(H2,27,32)(H,29,30)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17683 (2-aminobenzimidazole, 8 | 4-{[2-({3-[2-(dimethylam...) Show SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(c(OCCN(C)C)c4)C(F)(F)F)[nH]c3c2)ccn1 Show InChI InChI=1S/C25H25F3N6O3/c1-29-23(35)21-14-17(8-9-30-21)37-16-5-7-19-20(13-16)33-24(32-19)31-15-4-6-18(25(26,27)28)22(12-15)36-11-10-34(2)3/h4-9,12-14H,10-11H2,1-3H3,(H,29,35)(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	-48.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17691 (2-aminobenzimidazole, 16 | N-{4-chloro-3-[(4-methy...) Show SMILES CN1CCN(Cc2cc(Nc3nc4ccc(Oc5ccnc6[nH]ccc56)cc4[nH]3)ccc2Cl)CC1 Show InChI InChI=1S/C26H26ClN7O/c1-33-10-12-34(13-11-33)16-17-14-18(2-4-21(17)27)30-26-31-22-5-3-19(15-23(22)32-26)35-24-7-9-29-25-20(24)6-8-28-25/h2-9,14-15H,10-13,16H2,1H3,(H,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3	-48.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50302905 (7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3cc(C)ns3)ccnc2c1 Show InChI InChI=1S/C19H16N8OS/c1-11-7-16(29-26-11)13-3-4-17-23-24-18(27(17)25-13)10-21-14-5-6-20-15-8-12(28-2)9-22-19(14)15/h3-9H,10H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	3.20	-48.8	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164472 (US9066954, 297) Show SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3cc(C)no3)ccnc2c1 Show InChI InChI=1S/C21H17N5O3/c1-13-9-19(29-25-13)14-3-6-20-23-24-21(26(20)11-14)12-28-18-7-8-22-17-10-15(27-2)4-5-16(17)18/h3-11H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	-48.8	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17706 (2-aminobenzoxazole, 31 | N-{4-chloro-3-[(4-methylp...) Show SMILES CN1CCN(Cc2cc(Nc3nc4cc(Oc5ccnc6ccccc56)ccc4o3)ccc2Cl)CC1 Show InChI InChI=1S/C28H26ClN5O2/c1-33-12-14-34(15-13-33)18-19-16-20(6-8-23(19)29)31-28-32-25-17-21(7-9-27(25)36-28)35-26-10-11-30-24-5-3-2-4-22(24)26/h2-11,16-17H,12-15,18H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17682 (2-aminobenzimidazole, 7 | 4-{[2-({4-chloro-3-[(4-m...) Show SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)[nH]c3c2)ccn1 Show InChI InChI=1S/C26H28ClN7O2/c1-28-25(35)24-15-20(7-8-29-24)36-19-4-6-22-23(14-19)32-26(31-22)30-18-3-5-21(27)17(13-18)16-34-11-9-33(2)10-12-34/h3-8,13-15H,9-12,16H2,1-2H3,(H,28,35)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	-47.5	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17700 (2-aminobenzoxazole, 25 | 4-[(2-{[4-chloro-3-(morph...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(CN5CCOCC5)c4)nc3c2)ccn1 Show InChI InChI=1S/C25H24ClN5O4/c1-27-24(32)22-14-19(6-7-28-22)34-18-3-5-23-21(13-18)30-25(35-23)29-17-2-4-20(26)16(12-17)15-31-8-10-33-11-9-31/h2-7,12-14H,8-11,15H2,1H3,(H,27,32)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17695 (2-aminobenzoxazole, 20 | 4-{[2-({4-chloro-3-[(4-me...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)nc3c2)ccn1 Show InChI InChI=1S/C26H27ClN6O3/c1-28-25(34)23-15-20(7-8-29-23)35-19-4-6-24-22(14-19)31-26(36-24)30-18-3-5-21(27)17(13-18)16-33-11-9-32(2)10-12-33/h3-8,13-15H,9-12,16H2,1-2H3,(H,28,34)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	-47.5	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17698 (2-aminobenzoxazole, 23 | 4-{[2-({4-chloro-3-[2-(di...) Show SMILES CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(OCCN(C)C)c4)nc3c2)ccn1 Show InChI InChI=1S/C24H24ClN5O4/c1-26-23(31)20-14-17(8-9-27-20)33-16-5-7-21-19(13-16)29-24(34-21)28-15-4-6-18(25)22(12-15)32-11-10-30(2)3/h4-9,12-14H,10-11H2,1-3H3,(H,26,31)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164461 (US9066954, 226) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3cnc(C)s3)ccnc2c1 Show InChI InChI=1S/C20H16N6O2S/c1-12-22-10-18(29-12)15-5-6-19-23-24-20(26(19)25-15)11-28-17-7-8-21-16-9-13(27-2)3-4-14(16)17/h3-10H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.70	-47.9	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164455 (US9066954, 187) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1 Show InChI InChI=1S/C21H18N8O2/c1-28-12-13(3-6-20(28)30)15-4-5-18-25-26-19(29(18)27-15)11-23-16-7-8-22-17-9-14(31-2)10-24-21(16)17/h3-10,12H,11H2,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.90	-47.7	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17699 (2-aminobenzoxazole, 24 | 4-{[2-({4-chloro-3-[2-(di...) Show SMILES CCN(CC)CCOc1cc(Nc2nc3cc(Oc4ccnc(c4)C(=O)NC)ccc3o2)ccc1Cl Show InChI InChI=1S/C26H28ClN5O4/c1-4-32(5-2)12-13-34-24-14-17(6-8-20(24)27)30-26-31-21-15-18(7-9-23(21)36-26)35-19-10-11-29-22(16-19)25(33)28-3/h6-11,14-16H,4-5,12-13H2,1-3H3,(H,28,33)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164418 (US9066954, 52) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3ccc4C(=O)N(C)Cc4c3)ccnc2c1 Show InChI InChI=1S/C24H20N8O2/c1-31-13-15-9-14(3-4-17(15)24(31)33)18-5-6-21-28-29-22(32(21)30-18)12-26-19-7-8-25-20-10-16(34-2)11-27-23(19)20/h3-11H,12-13H2,1-2H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	-47.7	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164445 (US9066954, 140) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4N(C)CCOc4c3)ccnc2c1 Show InChI InChI=1S/C25H22N6O3/c1-30-11-12-33-23-13-16(3-7-21(23)30)19-6-8-24-27-28-25(31(24)29-19)15-34-22-9-10-26-20-14-17(32-2)4-5-18(20)22/h3-10,13-14H,11-12,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.20	-47.6	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164442 (US9066954, 121) Show SMILES FC(F)(c1nnc2ccc(nn12)-c1ccccc1)c1ccc2ncccc2c1 Show InChI InChI=1S/C21H13F2N5/c22-21(23,16-8-9-17-15(13-16)7-4-12-24-17)20-26-25-19-11-10-18(27-28(19)20)14-5-2-1-3-6-14/h1-13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.40	-47.5	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164454 (US9066954, 186) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1 Show InChI InChI=1S/C22H18N6O3/c1-27-12-14(3-8-22(27)29)17-6-7-20-24-25-21(28(20)26-17)13-31-19-9-10-23-18-11-15(30-2)4-5-16(18)19/h3-12H,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	-47.2	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164404 (US9066954, 18) Show SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3cn(C)nn3)ccnc2c1 Show InChI InChI=1S/C20H17N7O2/c1-26-11-17(22-25-26)13-3-6-19-23-24-20(27(19)10-13)12-29-18-7-8-21-16-9-14(28-2)4-5-15(16)18/h3-11H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.60	-47.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164463 (US9066954, 231) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc4C(=O)N(C)Cc4c3)ccnc2c1 Show InChI InChI=1S/C25H20N6O3/c1-30-13-16-11-15(3-5-18(16)25(30)32)20-7-8-23-27-28-24(31(23)29-20)14-34-22-9-10-26-21-12-17(33-2)4-6-19(21)22/h3-12H,13-14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.70	-47.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164419 (US9066954, 53) Show SMILES COc1cnc2c(NCc3nnc4ccc(nn34)-c3cnn(c3)C(C)C)ccnc2c1 Show InChI InChI=1S/C21H21N9O/c1-13(2)29-12-14(9-25-29)16-4-5-19-26-27-20(30(19)28-16)11-23-17-6-7-22-18-8-15(31-3)10-24-21(17)18/h4-10,12-13H,11H2,1-3H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.70	-47.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair

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