Compile Data Set for Download or QSAR

Found 81 hits with Last Name = 'pulley' and Initial = 'md'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374100 (CHEMBL270011) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(Cc3ccccc3)C[C@@H]12)N1CCCC1 |t:9| Show InChI InChI=1S/C26H32N2/c1-2-6-22(7-3-1)18-28-19-24-12-13-25(26(24)20-28)23-10-8-21(9-11-23)14-17-27-15-4-5-16-27/h1-3,6-11,13,24,26H,4-5,12,14-20H2/t24-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374104 (CHEMBL255962) Show SMILES CC1CCCN1CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12 |w:17.18,28.30,1.0,t:16| Show InChI InChI=1S/C27H34N2/c1-21-6-5-16-29(21)17-15-22-9-11-24(12-10-22)26-14-13-25-19-28(20-27(25)26)18-23-7-3-2-4-8-23/h2-4,7-12,14,21,25,27H,5-6,13,15-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50232355 ((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(CC3CC3)C[C@@H]12)N1CCCC1 |r,t:9| Show InChI InChI=1S/C23H32N2/c1-2-13-24(12-1)14-11-18-5-7-20(8-6-18)22-10-9-21-16-25(17-23(21)22)15-19-3-4-19/h5-8,10,19,21,23H,1-4,9,11-17H2/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50232355 ((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(CC3CC3)C[C@@H]12)N1CCCC1 |r,t:9| Show InChI InChI=1S/C23H32N2/c1-2-13-24(12-1)14-11-18-5-7-20(8-6-18)22-10-9-21-16-25(17-23(21)22)15-19-3-4-19/h5-8,10,19,21,23H,1-4,9,11-17H2/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374110 (CHEMBL401954) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C1CCCC1)N1CCCC1 |t:9| Show InChI InChI=1S/C24H34N2/c1-2-6-22(5-1)26-17-21-11-12-23(24(21)18-26)20-9-7-19(8-10-20)13-16-25-14-3-4-15-25/h7-10,12,21-22,24H,1-6,11,13-18H2/t21-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50232355 ((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(CC3CC3)C[C@@H]12)N1CCCC1 |r,t:9| Show InChI InChI=1S/C23H32N2/c1-2-13-24(12-1)14-11-18-5-7-20(8-6-18)22-10-9-21-16-25(17-23(21)22)15-19-3-4-19/h5-8,10,19,21,23H,1-4,9,11-17H2/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374102 (CHEMBL402297) Show SMILES OC[C@@H]1CCCN1CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12 |w:18.19,29.31,t:17| Show InChI InChI=1S/C27H34N2O/c30-20-25-7-4-15-29(25)16-14-21-8-10-23(11-9-21)26-13-12-24-18-28(19-27(24)26)17-22-5-2-1-3-6-22/h1-3,5-6,8-11,13,24-25,27,30H,4,7,12,14-20H2/t24?,25-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352357 (CHEMBL558655) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCc1ccncc1 Show InChI InChI=1S/C25H29N3O2S/c1-20-3-2-17-28(20)18-14-21-4-6-23(7-5-21)24-8-10-25(11-9-24)31(29,30)27-19-22-12-15-26-16-13-22/h4-13,15-16,20,27H,2-3,14,17-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374109 (CHEMBL255840) Show SMILES CC(C)N1C[C@@H]2CC=C([C@@H]2C1)c1ccc(CCN2CCCC2)cc1 |c:7| Show InChI InChI=1S/C22H32N2/c1-17(2)24-15-20-9-10-21(22(20)16-24)19-7-5-18(6-8-19)11-14-23-12-3-4-13-23/h5-8,10,17,20,22H,3-4,9,11-16H2,1-2H3/t20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352358 (CHEMBL558456) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C26H30N2O2S/c1-21-6-5-18-28(21)19-17-22-9-11-24(12-10-22)25-13-15-26(16-14-25)31(29,30)27-20-23-7-3-2-4-8-23/h2-4,7-16,21,27H,5-6,17-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243638 (1-((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)Cc1ccccc1 |r,t:16| Show InChI InChI=1S/C28H34N2O/c1-21-6-5-16-29(21)17-15-22-9-11-24(12-10-22)26-14-13-25-19-30(20-27(25)26)28(31)18-23-7-3-2-4-8-23/h2-4,7-12,14,21,25,27H,5-6,13,15-20H2,1H3/t21-,25+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374095 (CHEMBL255752) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12)N1CCCC1 |w:11.12,22.23,t:9| Show InChI InChI=1S/C26H32N2/c1-2-6-22(7-3-1)18-28-19-24-12-13-25(26(24)20-28)23-10-8-21(9-11-23)14-17-27-15-4-5-16-27/h1-3,6-11,13,24,26H,4-5,12,14-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374101 (CHEMBL410623) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(CC12)C1CCCC1)N1CCCC1 |w:11.12,15.15,t:9| Show InChI InChI=1S/C24H34N2/c1-2-6-22(5-1)26-17-21-11-12-23(24(21)18-26)20-9-7-19(8-10-20)13-16-25-14-3-4-15-25/h7-10,12,21-22,24H,1-6,11,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374098 (CHEMBL256225) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12)N1CCCCC1 |w:11.11,22.23,t:9| Show InChI InChI=1S/C27H34N2/c1-3-7-23(8-4-1)19-29-20-25-13-14-26(27(25)21-29)24-11-9-22(10-12-24)15-18-28-16-5-2-6-17-28/h1,3-4,7-12,14,25,27H,2,5-6,13,15-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243122 (2-methyl-1-((3aR,6aR)-6-(4-(2-((R)-2-methylpyrroli...) Show SMILES CC(C)C(=O)N1C[C@@H]2CC=C([C@@H]2C1)c1ccc(CCN2CCC[C@H]2C)cc1 |r,c:9| Show InChI InChI=1S/C24H34N2O/c1-17(2)24(27)26-15-21-10-11-22(23(21)16-26)20-8-6-19(7-9-20)12-14-25-13-4-5-18(25)3/h6-9,11,17-18,21,23H,4-5,10,12-16H2,1-3H3/t18-,21+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243123 (CHEMBL488464 | cyclopentyl((3aR,6aR)-6-(4-(2-((R)-...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)C1CCCC1 |r,t:16| Show InChI InChI=1S/C26H36N2O/c1-19-5-4-15-27(19)16-14-20-8-10-21(11-9-20)24-13-12-23-17-28(18-25(23)24)26(29)22-6-2-3-7-22/h8-11,13,19,22-23,25H,2-7,12,14-18H2,1H3/t19-,23+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50414743 (CHEMBL564803) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C27H30N2O2S/c1-21-5-4-17-28(21)18-16-22-8-10-23(11-9-22)24-12-14-27(15-13-24)32(30,31)29-19-25-6-2-3-7-26(25)20-29/h2-3,6-15,21H,4-5,16-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374103 (CHEMBL255961) Show SMILES OC[C@H]1CCCN1CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12 |w:18.19,29.31,t:17| Show InChI InChI=1S/C27H34N2O/c30-20-25-7-4-15-29(25)16-14-21-8-10-23(11-9-21)26-13-12-24-18-28(19-27(24)26)17-22-5-2-1-3-6-22/h1-3,5-6,8-11,13,24-25,27,30H,4,7,12,14-20H2/t24?,25-,27?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352354 (CHEMBL554506) Show SMILES COC1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCCC2C)cc1 Show InChI InChI=1S/C25H34N2O3S/c1-20-4-3-16-26(20)17-13-21-5-7-22(8-6-21)23-9-11-25(12-10-23)31(28,29)27-18-14-24(30-2)15-19-27/h5-12,20,24H,3-4,13-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243674 (((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)C1CCOCC1 |r,t:16| Show InChI InChI=1S/C26H36N2O2/c1-19-3-2-13-27(19)14-10-20-4-6-21(7-5-20)24-9-8-23-17-28(18-25(23)24)26(29)22-11-15-30-16-12-22/h4-7,9,19,22-23,25H,2-3,8,10-18H2,1H3/t19-,23+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374111 (CHEMBL409899) Show SMILES C(Cc1ccc(cc1)C1=CC[C@@H]2CN(Cc3ccccc3)C[C@H]12)N1CCCC1 |t:9| Show InChI InChI=1S/C26H32N2/c1-2-6-22(7-3-1)18-28-19-24-12-13-25(26(24)20-28)23-10-8-21(9-11-23)14-17-27-15-4-5-16-27/h1-3,6-11,13,24,26H,4-5,12,14-20H2/t24-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374107 (CHEMBL270440) Show SMILES CC(C)N1CC2CC=C(C2C1)c1ccc(CCN2CCCC2)cc1 |w:5.4,9.10,c:7| Show InChI InChI=1S/C22H32N2/c1-17(2)24-15-20-9-10-21(22(20)16-24)19-7-5-18(6-8-19)11-14-23-12-3-4-13-23/h5-8,10,17,20,22H,3-4,9,11-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50232355 ((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(CC3CC3)C[C@@H]12)N1CCCC1 |r,t:9| Show InChI InChI=1S/C23H32N2/c1-2-13-24(12-1)14-11-18-5-7-20(8-6-18)22-10-9-21-16-25(17-23(21)22)15-19-3-4-19/h5-8,10,19,21,23H,1-4,9,11-17H2/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor expressed in CHOK1 cells by [3H]R(-)-alpha-methylhistamine displacement assay				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352355 (CHEMBL560140) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C23H30N2O4S2/c1-19-3-2-13-24(19)14-12-20-4-6-21(7-5-20)22-8-10-23(11-9-22)31(28,29)25-15-17-30(26,27)18-16-25/h4-11,19H,2-3,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50297366 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES CCNS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C21H28N2O2S/c1-3-22-26(24,25)21-12-10-20(11-13-21)19-8-6-18(7-9-19)14-16-23-15-4-5-17(23)2/h6-13,17,22H,3-5,14-16H2,1-2H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inverse agonist activity against human histamine H3 receptor by [35S]GTPgamma binding assay				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50232355 ((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...) Show SMILES C(Cc1ccc(cc1)C1=CC[C@H]2CN(CC3CC3)C[C@@H]12)N1CCCC1 |r,t:9| Show InChI InChI=1S/C23H32N2/c1-2-13-24(12-1)14-11-18-5-7-20(8-6-18)22-10-9-21-16-25(17-23(21)22)15-19-3-4-19/h5-8,10,19,21,23H,1-4,9,11-17H2/t21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inverse agonist activity at human H3 receptor expressed in CHOK1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50297367 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC1CCOCC1 |r| Show InChI InChI=1S/C24H32N2O3S/c1-19-3-2-15-26(19)16-12-20-4-6-21(7-5-20)22-8-10-24(11-9-22)30(27,28)25-23-13-17-29-18-14-23/h4-11,19,23,25H,2-3,12-18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inverse agonist activity against human histamine H3 receptor by [35S]GTPgamma binding assay				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50297368 (4-{4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-bip...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 |r| Show InChI InChI=1S/C23H30N2O3S/c1-19-3-2-13-24(19)14-12-20-4-6-21(7-5-20)22-8-10-23(11-9-22)29(26,27)25-15-17-28-18-16-25/h4-11,19H,2-3,12-18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inverse agonist activity against human histamine H3 receptor by [35S]GTPgamma binding assay				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243639 (((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1cccnc1 |r,t:16| Show InChI InChI=1S/C26H31N3O/c1-19-4-3-14-28(19)15-12-20-6-8-21(9-7-20)24-11-10-23-17-29(18-25(23)24)26(30)22-5-2-13-27-16-22/h2,5-9,11,13,16,19,23,25H,3-4,10,12,14-15,17-18H2,1H3/t19-,23+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50414742 (CHEMBL560799) Show SMILES CCN(CC)S(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCCC2C)cc1 Show InChI InChI=1S/C23H32N2O2S/c1-4-25(5-2)28(26,27)23-14-12-22(13-15-23)21-10-8-20(9-11-21)16-18-24-17-6-7-19(24)3/h8-15,19H,4-7,16-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50297368 (4-{4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-bip...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 |r| Show InChI InChI=1S/C23H30N2O3S/c1-19-3-2-13-24(19)14-12-20-4-6-21(7-5-20)22-8-10-23(11-9-22)29(26,27)25-15-17-28-18-16-25/h4-11,19H,2-3,12-18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352364 (CHEMBL562629) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C24H32N2O2S/c1-20-6-5-16-25(20)19-15-21-7-9-22(10-8-21)23-11-13-24(14-12-23)29(27,28)26-17-3-2-4-18-26/h7-14,20H,2-6,15-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374097 (CHEMBL255166) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12)N1CCOCC1 |w:11.11,22.23,t:9| Show InChI InChI=1S/C26H32N2O/c1-2-4-22(5-3-1)18-28-19-24-10-11-25(26(24)20-28)23-8-6-21(7-9-23)12-13-27-14-16-29-17-15-27/h1-9,11,24,26H,10,12-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50297367 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC1CCOCC1 |r| Show InChI InChI=1S/C24H32N2O3S/c1-19-3-2-15-26(19)16-12-20-4-6-21(7-5-20)22-8-10-24(11-9-22)30(27,28)25-23-13-17-29-18-14-23/h4-11,19,23,25H,2-3,12-18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352359 (CHEMBL552279) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C25H28N2O2S/c1-20-6-5-18-27(20)19-17-21-9-11-22(12-10-21)23-13-15-25(16-14-23)30(28,29)26-24-7-3-2-4-8-24/h2-4,7-16,20,26H,5-6,17-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374105 (CHEMBL429418) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(CC12)c1ccccn1)N1CCCC1 |w:11.12,15.15,t:9| Show InChI InChI=1S/C24H29N3/c1-2-13-25-24(5-1)27-17-21-10-11-22(23(21)18-27)20-8-6-19(7-9-20)12-16-26-14-3-4-15-26/h1-2,5-9,11,13,21,23H,3-4,10,12,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50243674 (((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)C1CCOCC1 |r,t:16| Show InChI InChI=1S/C26H36N2O2/c1-19-3-2-13-27(19)14-10-20-4-6-21(7-5-20)24-9-8-23-17-28(18-25(23)24)26(29)22-11-15-30-16-12-22/h4-7,9,19,22-23,25H,2-3,8,10-18H2,1H3/t19-,23+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor expressed in CHOK1 cells by [3H]R(-)-alpha-methylhistamine displacement assay				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352360 (CHEMBL563118) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC1CCC1 Show InChI InChI=1S/C23H30N2O2S/c1-18-4-3-16-25(18)17-15-19-7-9-20(10-8-19)21-11-13-23(14-12-21)28(26,27)24-22-5-2-6-22/h7-14,18,22,24H,2-6,15-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374108 (CHEMBL273202) Show SMILES CN(C)CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12 |w:14.15,25.26,t:12| Show InChI InChI=1S/C24H30N2/c1-25(2)15-14-19-8-10-21(11-9-19)23-13-12-22-17-26(18-24(22)23)16-20-6-4-3-5-7-20/h3-11,13,22,24H,12,14-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374099 (CHEMBL256648) Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12)N1CCC1 |w:11.12,22.23,t:9| Show InChI InChI=1S/C25H30N2/c1-2-5-21(6-3-1)17-27-18-23-11-12-24(25(23)19-27)22-9-7-20(8-10-22)13-16-26-14-4-15-26/h1-3,5-10,12,23,25H,4,11,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352353 (CHEMBL1823053) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCC(O)C1 |r| Show InChI InChI=1S/C23H30N2O3S/c1-18-3-2-14-24(18)15-12-19-4-6-20(7-5-19)21-8-10-23(11-9-21)29(27,28)25-16-13-22(26)17-25/h4-11,18,22,26H,2-3,12-17H2,1H3/t18-,22?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50352361 (CHEMBL558260) Show SMILES CC1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NCC1CC1 Show InChI InChI=1S/C23H30N2O2S/c1-18-3-2-15-25(18)16-14-19-6-8-21(9-7-19)22-10-12-23(13-11-22)28(26,27)24-17-20-4-5-20/h6-13,18,20,24H,2-5,14-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50374094 (CHEMBL402296) Show SMILES FC1(F)CCN(CCc2ccc(cc2)C2=CCC3CN(Cc4ccccc4)CC23)C1 |w:17.17,28.29,t:15| Show InChI InChI=1S/C26H30F2N2/c27-26(28)13-15-29(19-26)14-12-20-6-8-22(9-7-20)24-11-10-23-17-30(18-25(23)24)16-21-4-2-1-3-5-21/h1-9,11,23,25H,10,12-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex				Bioorg Med Chem Lett 18: 1490-4 (2008) Article DOI: 10.1016/j.bmcl.2007.12.059 BindingDB Entry DOI: 10.7270/Q2Q81DZS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243120 (CHEMBL520719 | cyclopentyl((3aR,6aR)-6-(4-(2-(pyrr...) Show SMILES O=C(C1CCCC1)N1C[C@@H]2CC=C([C@@H]2C1)c1ccc(CCN2CCCC2)cc1 |r,c:12| Show InChI InChI=1S/C25H34N2O/c28-25(21-5-1-2-6-21)27-17-22-11-12-23(24(22)18-27)20-9-7-19(8-10-20)13-16-26-14-3-4-15-26/h7-10,12,21-22,24H,1-6,11,13-18H2/t22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243175 (((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1ccccc1 |r,t:16| Show InChI InChI=1S/C27H32N2O/c1-20-6-5-16-28(20)17-15-21-9-11-22(12-10-21)25-14-13-24-18-29(19-26(24)25)27(30)23-7-3-2-4-8-23/h2-4,7-12,14,20,24,26H,5-6,13,15-19H2,1H3/t20-,24+,26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50297369 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES COCCNS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C22H30N2O3S/c1-18-4-3-15-24(18)16-13-19-5-7-20(8-6-19)21-9-11-22(12-10-21)28(25,26)23-14-17-27-2/h5-12,18,23H,3-4,13-17H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50297368 (4-{4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-bip...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCOCC1 |r| Show InChI InChI=1S/C23H30N2O3S/c1-19-3-2-13-24(19)14-12-20-4-6-21(7-5-20)22-8-10-23(11-9-22)29(26,27)25-15-17-28-18-16-25/h4-11,19H,2-3,12-18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50243674 (((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)C1CCOCC1 |r,t:16| Show InChI InChI=1S/C26H36N2O2/c1-19-3-2-13-27(19)14-10-20-4-6-21(7-5-20)24-9-8-23-17-28(18-25(23)24)26(29)22-11-15-30-16-12-22/h4-7,9,19,22-23,25H,2-3,8,10-18H2,1H3/t19-,23+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inverse agonist activity at human H3 receptor expressed in CHOK1 cells by GTPgammaS binding assay				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50243676 (((3aR,6aR)-6-(4-(2-(pyrrolidin-1-yl)ethyl)phenyl)-...) Show SMILES O=C(C1CCOC1)N1C[C@@H]2CC=C([C@@H]2C1)c1ccc(CCN2CCCC2)cc1 |r,c:12| Show InChI InChI=1S/C24H32N2O2/c27-24(21-10-14-28-17-21)26-15-20-7-8-22(23(20)16-26)19-5-3-18(4-6-19)9-13-25-11-1-2-12-25/h3-6,8,20-21,23H,1-2,7,9-17H2/t20-,21?,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				Bioorg Med Chem Lett 18: 4133-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.086 BindingDB Entry DOI: 10.7270/Q2C82942
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50414741 (CHEMBL550198) Show SMILES CC(C)NS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCCC2C)cc1 Show InChI InChI=1S/C22H30N2O2S/c1-17(2)23-27(25,26)22-12-10-21(11-13-22)20-8-6-19(7-9-20)14-16-24-15-4-5-18(24)3/h6-13,17-18,23H,4-5,14-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair

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