Found 1313 hits with Last Name = 'winters' and Initial = 't' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373326
(CHEMBL444278)Show SMILES CNc1nc(I)nc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@]2(COP(O)(O)=O)C[C@H]12 Show InChI InChI=1S/C13H18IN5O8P2/c1-15-10-9-11(18-12(14)17-10)19(5-16-9)7-2-8(27-29(23,24)25)13(3-6(7)13)4-26-28(20,21)22/h5-8H,2-4H2,1H3,(H,15,17,18)(H2,20,21,22)(H2,23,24,25)/t6-,7+,8+,13+/m1/s1 | PDB
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Article
PubMed
| 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373304
(CHEMBL255724)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(cc1)C1CCCCC1 Show InChI InChI=1S/C31H34N4O2/c1-3-23-11-7-9-15-28(23)35-30(21-22(2)34-35)37-29-16-10-8-14-27(29)33-31(36)32-26-19-17-25(18-20-26)24-12-5-4-6-13-24/h7-11,14-21,24H,3-6,12-13H2,1-2H3,(H2,32,33,36) | PDB
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PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373331
(CHEMBL255095)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(cc1)C(C)C Show InChI InChI=1S/C28H30N4O2/c1-5-21-10-6-8-12-25(21)32-27(18-20(4)31-32)34-26-13-9-7-11-24(26)30-28(33)29-23-16-14-22(15-17-23)19(2)3/h6-19H,5H2,1-4H3,(H2,29,30,33) | PDB
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373303
(CHEMBL256141)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C2CCCCC2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C29H29ClN4O2/c1-20-19-28(34(33-20)26-13-7-5-11-24(26)30)36-27-14-8-6-12-25(27)32-29(35)31-23-17-15-22(16-18-23)21-9-3-2-4-10-21/h5-8,11-19,21H,2-4,9-10H2,1H3,(H2,31,32,35) | PDB
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| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373305
(CHEMBL256088)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C2CCCC2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C28H27ClN4O2/c1-19-18-27(33(32-19)25-12-6-4-10-23(25)29)35-26-13-7-5-11-24(26)31-28(34)30-22-16-14-21(15-17-22)20-8-2-3-9-20/h4-7,10-18,20H,2-3,8-9H2,1H3,(H2,30,31,34) | PDB
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| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373324
(CHEMBL258406)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H23F3N4O3/c1-3-18-8-4-6-10-22(18)33-24(16-17(2)32-33)35-23-11-7-5-9-21(23)31-25(34)30-19-12-14-20(15-13-19)36-26(27,28)29/h4-16H,3H2,1-2H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373330
(CHEMBL257559)Show SMILES CC(C)c1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C27H25F3N4O3/c1-17(2)21-8-4-6-10-23(21)34-25(16-18(3)33-34)36-24-11-7-5-9-22(24)32-26(35)31-19-12-14-20(15-13-19)37-27(28,29)30/h4-17H,1-3H3,(H2,31,32,35) | PDB
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| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373307
(CHEMBL402837)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H23F3N4O2/c1-3-18-8-4-6-10-22(18)33-24(16-17(2)32-33)35-23-11-7-5-9-21(23)31-25(34)30-20-14-12-19(13-15-20)26(27,28)29/h4-16H,3H2,1-2H3,(H2,30,31,34) | PDB
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PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373293
(CHEMBL255307)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H22F3N5O3/c1-3-17-7-4-5-9-21(17)33-22(15-16(2)32-33)35-23-20(8-6-14-29-23)31-24(34)30-18-10-12-19(13-11-18)36-25(26,27)28/h4-15H,3H2,1-2H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
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| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373323
(CHEMBL255306)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C24H18ClF3N4O3/c1-15-14-22(32(31-15)20-8-4-2-6-18(20)25)34-21-9-5-3-7-19(21)30-23(33)29-16-10-12-17(13-11-16)35-24(26,27)28/h2-14H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373308
(CHEMBL256776)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C(C)(C)C)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C27H27ClN4O2/c1-18-17-25(32(31-18)23-11-7-5-9-21(23)28)34-24-12-8-6-10-22(24)30-26(33)29-20-15-13-19(14-16-20)27(2,3)4/h5-17H,1-4H3,(H2,29,30,33) | PDB
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| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373306
(CHEMBL256089)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C2CC2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C26H23ClN4O2/c1-17-16-25(31(30-17)23-8-4-2-6-21(23)27)33-24-9-5-3-7-22(24)29-26(32)28-20-14-12-19(13-15-20)18-10-11-18/h2-9,12-16,18H,10-11H2,1H3,(H2,28,29,32) | PDB
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| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373322
(CHEMBL255094)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C24H18ClF3N4O3/c1-15-13-22(32(31-15)18-6-4-5-16(25)14-18)34-21-8-3-2-7-20(21)30-23(33)29-17-9-11-19(12-10-17)35-24(26,27)28/h2-14H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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UniChem
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| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373310
(CHEMBL402563)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN4O2/c1-3-18-8-4-6-10-22(18)30-24(16-17(2)29-30)32-23-11-7-5-9-21(23)28-25(31)27-20-14-12-19(26)13-15-20/h4-16H,3H2,1-2H3,(H2,27,28,31) | PDB
UniProtKB/SwissProt
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UniChem
Similars
| Article
PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373320
(CHEMBL403879)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C25H18F6N4O3/c1-15-14-22(35(34-15)20-8-4-2-6-18(20)24(26,27)28)37-21-9-5-3-7-19(21)33-23(36)32-16-10-12-17(13-11-16)38-25(29,30)31/h2-14H,1H3,(H2,32,33,36) | PDB
UniProtKB/SwissProt
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| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373292
(CHEMBL255308)Show SMILES Cc1cc(Oc2ncccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C23H17ClF3N5O3/c1-14-13-20(32(31-14)19-7-3-2-5-17(19)24)34-21-18(6-4-12-28-21)30-22(33)29-15-8-10-16(11-9-15)35-23(25,26)27/h2-13H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373319
(CHEMBL255728)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1C Show InChI InChI=1S/C25H21F3N4O3/c1-16-7-3-5-9-21(16)32-23(15-17(2)31-32)34-22-10-6-4-8-20(22)30-24(33)29-18-11-13-19(14-12-18)35-25(26,27)28/h3-15H,1-2H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373311
(CHEMBL255310)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C31H28N4O3/c1-3-23-11-7-9-15-28(23)35-30(21-22(2)34-35)38-29-16-10-8-14-27(29)33-31(36)32-24-17-19-26(20-18-24)37-25-12-5-4-6-13-25/h4-21H,3H2,1-2H3,(H2,32,33,36) | PDB
UniProtKB/SwissProt
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| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50240720
((2S,3S,4S,5R,6S)-6-(4-((2S,3R)-1-(4-fluorophenyl)-...)Show SMILES O[C@@H](CC[C@@H]1[C@H](N(C1=O)c1ccc(F)cc1)c1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C30H29F2NO9/c31-17-5-1-15(2-6-17)22(34)14-13-21-23(33(28(21)38)19-9-7-18(32)8-10-19)16-3-11-20(12-4-16)41-30-26(37)24(35)25(36)27(42-30)29(39)40/h1-12,21-27,30,34-37H,13-14H2,(H,39,40)/t21-,22+,23-,24+,25+,26-,27+,30-/m1/s1 | PDB
Reactome pathway
KEGG
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MCE
KEGG
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Similars
| Article
PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371521
(EZETIMIBE)Show SMILES O[C@@H](CC[C@@H]1[C@H](N(C1=O)c1ccc(F)cc1)c1ccc(O)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1 | PDB
Reactome pathway
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| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373312
(CHEMBL404869)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C28H30N4O3/c1-5-21-10-6-8-12-25(21)32-27(18-20(4)31-32)35-26-13-9-7-11-24(26)30-28(33)29-22-14-16-23(17-15-22)34-19(2)3/h6-19H,5H2,1-4H3,(H2,29,30,33) | PDB
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UniChem
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| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373321
(CHEMBL257560)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H18ClF3N4O3/c1-15-14-22(32(31-15)18-10-6-16(25)7-11-18)34-21-5-3-2-4-20(21)30-23(33)29-17-8-12-19(13-9-17)35-24(26,27)28/h2-14H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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PC sid
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PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373329
(CHEMBL255726)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1F Show InChI InChI=1S/C24H18F4N4O3/c1-15-14-22(32(31-15)20-8-4-2-6-18(20)25)34-21-9-5-3-7-19(21)30-23(33)29-16-10-12-17(13-11-16)35-24(26,27)28/h2-14H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373317
(CHEMBL257378)Show SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2ccccc2Oc2ccnn2-c2ccccc2)cc1 Show InChI InChI=1S/C23H17F3N4O3/c24-23(25,26)33-18-12-10-16(11-13-18)28-22(31)29-19-8-4-5-9-20(19)32-21-14-15-27-30(21)17-6-2-1-3-7-17/h1-15H,(H2,28,29,31) | PDB
UniProtKB/SwissProt
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PubMed
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373288
(CHEMBL403555)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C24H19F3N4O3/c1-16-15-22(31(30-16)18-7-3-2-4-8-18)33-21-10-6-5-9-20(21)29-23(32)28-17-11-13-19(14-12-17)34-24(25,26)27/h2-15H,1H3,(H2,28,29,32) | PDB
UniProtKB/SwissProt
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PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373313
(CHEMBL401657)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(OC)cc1 Show InChI InChI=1S/C26H26N4O3/c1-4-19-9-5-7-11-23(19)30-25(17-18(2)29-30)33-24-12-8-6-10-22(24)28-26(31)27-20-13-15-21(32-3)16-14-20/h5-17H,4H2,1-3H3,(H2,27,28,31) | PDB
UniProtKB/SwissProt
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PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373327
(CHEMBL402597)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccccc1 Show InChI InChI=1S/C25H24N4O2/c1-3-19-11-7-9-15-22(19)29-24(17-18(2)28-29)31-23-16-10-8-14-21(23)27-25(30)26-20-12-5-4-6-13-20/h4-17H,3H2,1-2H3,(H2,26,27,30) | PDB
UniProtKB/SwissProt
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PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373302
(CHEMBL255447)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C2CCOCC2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C28H27ClN4O3/c1-19-18-27(33(32-19)25-8-4-2-6-23(25)29)36-26-9-5-3-7-24(26)31-28(34)30-22-12-10-20(11-13-22)21-14-16-35-17-15-21/h2-13,18,21H,14-17H2,1H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373318
(CHEMBL255727)Show SMILES COc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H21F3N4O4/c1-16-15-23(32(31-16)20-8-4-6-10-22(20)34-2)35-21-9-5-3-7-19(21)30-24(33)29-17-11-13-18(14-12-17)36-25(26,27)28/h3-15H,1-2H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373299
(CHEMBL258235)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)-c2cnco2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C26H20ClN5O3/c1-17-14-25(32(31-17)22-8-4-2-6-20(22)27)35-23-9-5-3-7-21(23)30-26(33)29-19-12-10-18(11-13-19)24-15-28-16-34-24/h2-16H,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
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PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371519
(CHEMBL271655)Show SMILES COc1ccc([C@@H]2[C@H](OC(=O)N2c2cccc(F)c2)C(=O)N(C)Cc2ccc(F)cc2)c(O)c1 Show InChI InChI=1S/C25H22F2N2O5/c1-28(14-15-6-8-16(26)9-7-15)24(31)23-22(20-11-10-19(33-2)13-21(20)30)29(25(32)34-23)18-5-3-4-17(27)12-18/h3-13,22-23,30H,14H2,1-2H3/t22-,23+/m1/s1 | PDB
Reactome pathway
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Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373325
(CHEMBL258407)Show SMILES Clc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)c(Oc2ccccc2)c1 Show InChI InChI=1S/C19H13Cl3N2O2/c20-12-6-9-17(18(10-12)26-14-4-2-1-3-5-14)24-19(25)23-13-7-8-15(21)16(22)11-13/h1-11H,(H2,23,24,25) | PDB
UniProtKB/SwissProt
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PC sid
UniChem
| Article
PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371538
(CHEMBL271634)Show SMILES COc1ccc([C@@H]2[C@H](OC(=O)N2c2cccc(F)c2)[C@H](O)CCc2ccccc2)c(O)c1 Show InChI InChI=1S/C25H24FNO5/c1-31-19-11-12-20(22(29)15-19)23-24(21(28)13-10-16-6-3-2-4-7-16)32-25(30)27(23)18-9-5-8-17(26)14-18/h2-9,11-12,14-15,21,23-24,28-29H,10,13H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
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Similars
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PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373309
(CHEMBL430029)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(F)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C23H19FN4O2/c1-16-15-22(28(27-16)19-7-3-2-4-8-19)30-21-10-6-5-9-20(21)26-23(29)25-18-13-11-17(24)12-14-18/h2-15H,1H3,(H2,25,26,29) | PDB
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PubMed
| 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371523
(CHEMBL258358)Show SMILES COc1ccc([C@@H]2[C@H](OC(=O)N2c2cccc(F)c2)C(=O)N2CCc3ccccc3C2)c(O)c1 Show InChI InChI=1S/C26H23FN2O5/c1-33-20-9-10-21(22(30)14-20)23-24(34-26(32)29(23)19-8-4-7-18(27)13-19)25(31)28-12-11-16-5-2-3-6-17(16)15-28/h2-10,13-14,23-24,30H,11-12,15H2,1H3/t23-,24+/m1/s1 | PDB
Reactome pathway
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Similars
| Article
PubMed
| 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371520
(CHEMBL257848)Show SMILES COc1ccc([C@@H]2[C@H](OC(=O)N2c2ccc(F)cc2)[C@H](O)CCc2ccccc2)c(O)c1 Show InChI InChI=1S/C25H24FNO5/c1-31-19-12-13-20(22(29)15-19)23-24(21(28)14-7-16-5-3-2-4-6-16)32-25(30)27(23)18-10-8-17(26)9-11-18/h2-6,8-13,15,21,23-24,28-29H,7,14H2,1H3/t21-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373332
(CHEMBL255505)Show InChI InChI=1S/C13H8Cl4N2O/c14-7-3-8(15)5-10(4-7)19-13(20)18-9-1-2-11(16)12(17)6-9/h1-6H,(H2,18,19,20) | PDB
UniProtKB/SwissProt
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PubMed
| 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373290
(CHEMBL255093)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(cn1)C(C)C Show InChI InChI=1S/C27H29N5O2/c1-5-20-10-6-8-12-23(20)32-26(16-19(4)31-32)34-24-13-9-7-11-22(24)29-27(33)30-25-15-14-21(17-28-25)18(2)3/h6-18H,5H2,1-4H3,(H2,28,29,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371537
(CHEMBL402421)Show SMILES COc1cccc([C@@H]2[C@H](OC(=O)N2c2cccc(F)c2)[C@H](O)CCc2ccccc2)c1O Show InChI InChI=1S/C25H24FNO5/c1-31-21-12-6-11-19(23(21)29)22-24(20(28)14-13-16-7-3-2-4-8-16)32-25(30)27(22)18-10-5-9-17(26)15-18/h2-12,15,20,22,24,28-29H,13-14H2,1H3/t20-,22-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373315
(CHEMBL255278)Show SMILES COC(=O)c1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C(C)(C)C)n(n1)-c1ccccc1 Show InChI InChI=1S/C28H28N4O4/c1-28(2,3)19-14-16-20(17-15-19)29-27(34)30-22-12-8-9-13-24(22)36-25-18-23(26(33)35-4)31-32(25)21-10-6-5-7-11-21/h5-18H,1-4H3,(H2,29,30,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371542
(CHEMBL439420)Show SMILES COc1cccc(OC[C@@H](O)[C@H]2OC(=O)N([C@@H]2c2ccc(OC)cc2O)c2cccc(F)c2)c1 Show InChI InChI=1S/C25H24FNO7/c1-31-17-7-4-8-19(12-17)33-14-22(29)24-23(20-10-9-18(32-2)13-21(20)28)27(25(30)34-24)16-6-3-5-15(26)11-16/h3-13,22-24,28-29H,14H2,1-2H3/t22-,23-,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371528
(CHEMBL257850)Show SMILES O[C@H](CCc1ccccc1)[C@H]1OC(=O)N([C@@H]1c1ccc(O)cc1O)c1ccc(F)cc1 Show InChI InChI=1S/C24H22FNO5/c25-16-7-9-17(10-8-16)26-22(19-12-11-18(27)14-21(19)29)23(31-24(26)30)20(28)13-6-15-4-2-1-3-5-15/h1-5,7-12,14,20,22-23,27-29H,6,13H2/t20-,22-,23-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
NPC1-like intracellular cholesterol transporter 1
(Rattus norvegicus) | BDBM50371533
(CHEMBL258061)Show SMILES O[C@@H](CC[C@H]1OC(=O)N([C@@H]1c1ccc(O)cc1)c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C24H21F2NO4/c25-17-5-1-15(2-6-17)21(29)13-14-22-23(16-3-11-20(28)12-4-16)27(24(30)31-22)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane |
Bioorg Med Chem Lett 18: 546-53 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373328
(CHEMBL257136)Show SMILES CCc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C25H21F3N4O3/c1-2-17-16-23(32(31-17)19-8-4-3-5-9-19)34-22-11-7-6-10-21(22)30-24(33)29-18-12-14-20(15-13-18)35-25(26,27)28/h3-16H,2H2,1H3,(H2,29,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373316
(CHEMBL428431)Show SMILES CC(C)c1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H23F3N4O3/c1-17(2)22-16-24(33(32-22)19-8-4-3-5-9-19)35-23-11-7-6-10-21(23)31-25(34)30-18-12-14-20(15-13-18)36-26(27,28)29/h3-17H,1-2H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373314
(CHEMBL258429)Show SMILES CC(C)(C)c1ccc(NC(=O)Nc2ccccc2Oc2cc(nn2-c2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C27H26N4O4/c1-27(2,3)18-13-15-19(16-14-18)28-26(34)29-21-11-7-8-12-23(21)35-24-17-22(25(32)33)30-31(24)20-9-5-4-6-10-20/h4-17H,1-3H3,(H,32,33)(H2,28,29,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373289
(CHEMBL403824)Show SMILES CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C25H22F3N5O2/c1-3-17-8-4-6-10-20(17)33-23(14-16(2)32-33)35-21-11-7-5-9-19(21)31-24(34)30-18-12-13-22(29-15-18)25(26,27)28/h4-15H,3H2,1-2H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373291
(CHEMBL255252)Show SMILES Cc1cc(Oc2ccncc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C23H18F3N5O3/c1-15-13-21(31(30-15)17-5-3-2-4-6-17)33-20-11-12-27-14-19(20)29-22(32)28-16-7-9-18(10-8-16)34-23(24,25)26/h2-14H,1H3,(H2,28,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373294
(CHEMBL255506)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(n1)-c1ccccn1 Show InChI InChI=1S/C23H18F3N5O3/c1-15-14-21(31(30-15)20-8-4-5-13-27-20)33-19-7-3-2-6-18(19)29-22(32)28-16-9-11-17(12-10-16)34-23(24,25)26/h2-14H,1H3,(H2,28,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
P2Y purinoceptor 1
(Homo sapiens (Human)) | BDBM50373301
(CHEMBL256944)Show SMILES Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(cc2)C2CCS(=O)(=O)CC2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C28H27ClN4O4S/c1-19-18-27(33(32-19)25-8-4-2-6-23(25)29)37-26-9-5-3-7-24(26)31-28(34)30-22-12-10-20(11-13-22)21-14-16-38(35,36)17-15-21/h2-13,18,21H,14-17H2,1H3,(H2,30,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human P2Y1 receptor |
Bioorg Med Chem Lett 18: 3338-43 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.028
BindingDB Entry DOI: 10.7270/Q2X34Z95 |
More data for this
Ligand-Target Pair | |
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