Compile Data Set for Download or QSAR

Found 81 hits with Last Name = 'zhang' and Initial = 'aq'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343301 (2-((4-(4-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(F)cc2)nc2ccccc12 Show InChI InChI=1S/C20H22FN3/c1-23-19-5-3-2-4-18(19)22-20(23)14-24-12-10-16(11-13-24)15-6-8-17(21)9-7-15/h2-9,16H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343305 (2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)meth...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(Cl)cc2F)nc2ccccc12 Show InChI InChI=1S/C20H21ClFN3/c1-24-19-5-3-2-4-18(19)23-20(24)13-25-10-8-14(9-11-25)16-7-6-15(21)12-17(16)22/h2-7,12,14H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343299 (2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2ccccc2F)nc2ccccc12 Show InChI InChI=1S/C20H22FN3/c1-23-19-9-5-4-8-18(19)22-20(23)14-24-12-10-15(11-13-24)16-6-2-3-7-17(16)21/h2-9,15H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343317 (1-methyl-2-(((1R,5S)-3-(4-(trifluoromethyl)phenyl)...) Show SMILES Cn1c(CN2[C@H]3CC[C@@H]2CC(C3)c2ccc(cc2)C(F)(F)F)nc2ncccc12 |r,THB:12:10:4:7.6| Show InChI InChI=1S/C22H23F3N4/c1-28-19-3-2-10-26-21(19)27-20(28)13-29-17-8-9-18(29)12-15(11-17)14-4-6-16(7-5-14)22(23,24)25/h2-7,10,15,17-18H,8-9,11-13H2,1H3/t15?,17-,18+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343308 (1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2ncccc12 Show InChI InChI=1S/C20H21F3N4/c1-26-17-3-2-10-24-19(17)25-18(26)13-27-11-8-15(9-12-27)14-4-6-16(7-5-14)20(21,22)23/h2-7,10,15H,8-9,11-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343295 (2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...) Show SMILES COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1 Show InChI InChI=1S/C21H25N3O/c1-23-19-9-5-4-8-18(19)22-21(23)15-24-13-11-16(12-14-24)17-7-3-6-10-20(17)25-2/h3-10,16H,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343306 (1-methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2ccccc12 Show InChI InChI=1S/C21H22F3N3/c1-26-19-5-3-2-4-18(19)25-20(26)14-27-12-10-16(11-13-27)15-6-8-17(9-7-15)21(22,23)24/h2-9,16H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	561	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343316 (CHEMBL1774224 | cis-1-methyl-2-(((2R,4R)-2-methyl-...) Show SMILES C[C@@H]1C[C@@H](CCN1Cc1nc2ncccc2n1C)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H23F3N4/c1-14-12-16(15-5-7-17(8-6-15)21(22,23)24)9-11-28(14)13-19-26-20-18(27(19)2)4-3-10-25-20/h3-8,10,14,16H,9,11-13H2,1-2H3/t14-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343309 (1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2cnccc12 Show InChI InChI=1S/C20H21F3N4/c1-26-18-6-9-24-12-17(18)25-19(26)13-27-10-7-15(8-11-27)14-2-4-16(5-3-14)20(21,22)23/h2-6,9,12,15H,7-8,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	671	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343314 (2-((4-(2-Fluoro-4-(trifluoromethoxy)phenyl)piperid...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(OC(F)(F)F)cc2F)nc2ncccc12 Show InChI InChI=1S/C20H20F4N4O/c1-27-17-3-2-8-25-19(17)26-18(27)12-28-9-6-13(7-10-28)15-5-4-14(11-16(15)21)29-20(22,23)24/h2-5,8,11,13H,6-7,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343321 (CHEMBL1774229 | cis-2-(((3R,4R)-4-(4-chloro-2-fluo...) Show SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(Cl)cc1F |r| Show InChI InChI=1S/C20H22ClFN4/c1-13-11-26(9-7-15(13)16-6-5-14(21)10-17(16)22)12-19-24-20-18(25(19)2)4-3-8-23-20/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343313 (2-((4-(2-Fluoro-4-(trifluoromethyl)phenyl)piperidi...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(cc2F)C(F)(F)F)nc2ncccc12 Show InChI InChI=1S/C20H20F4N4/c1-27-17-3-2-8-25-19(17)26-18(27)12-28-9-6-13(7-10-28)15-5-4-14(11-16(15)21)20(22,23)24/h2-5,8,11,13H,6-7,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343312 (2-((4-(2-Methoxy-4-(trifluoromethyl)phenyl)piperid...) Show SMILES COc1cc(ccc1C1CCN(Cc2nc3ncccc3n2C)CC1)C(F)(F)F Show InChI InChI=1S/C21H23F3N4O/c1-27-17-4-3-9-25-20(17)26-19(27)13-28-10-7-14(8-11-28)16-6-5-15(21(22,23)24)12-18(16)29-2/h3-6,9,12,14H,7-8,10-11,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343320 (CHEMBL1774228 | cis-1-methyl-2-(((3S,4S)-3-methyl-...) Show SMILES C[C@@H]1CN(Cc2nc3ncccc3n2C)CC[C@@H]1c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343319 (CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...) Show SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343318 ((S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)...) Show SMILES Cn1c(CN2CC[C@@H](c3ccc(cc3)C(F)(F)F)C(C)(C)C2)nc2ncccc12 |r| Show InChI InChI=1S/C22H25F3N4/c1-21(2)14-29(13-19-27-20-18(28(19)3)5-4-11-26-20)12-10-17(21)15-6-8-16(9-7-15)22(23,24)25/h4-9,11,17H,10,12-14H2,1-3H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343319 (CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...) Show SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343327 (CHEMBL1774235 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...) Show SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(OC(F)(F)F)cc1F |r| Show InChI InChI=1S/C21H22F4N4O/c1-13-11-29(12-19-27-20-18(28(19)2)4-3-8-26-20)9-7-15(13)16-6-5-14(10-17(16)22)30-21(23,24)25/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343325 (CHEMBL1774233 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...) Show SMILES C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C21H22F4N4/c1-13-11-29(12-19-27-20-18(28(19)2)4-3-8-26-20)9-7-15(13)16-6-5-14(10-17(16)22)21(23,24)25/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50343323 (CHEMBL1774231 | cis-2-(((3R,4R)-4-(2-methoxy-4-(tr...) Show SMILES COc1cc(ccc1[C@@H]1CCN(Cc2nc3ncccc3n2C)C[C@@H]1C)C(F)(F)F |r| Show InChI InChI=1S/C22H25F3N4O/c1-14-12-29(13-20-27-21-18(28(20)2)5-4-9-26-21)10-8-16(14)17-7-6-15(22(23,24)25)11-19(17)30-3/h4-7,9,11,14,16H,8,10,12-13H2,1-3H3/t14-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263432 (2-(((1R,5S)-6-((6-chloropyridin-3-yloxy)methyl)-3-...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(Cl)nc4)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C20H21ClN4O/c1-24-18-5-3-2-4-17(18)23-20(24)11-25-9-14-15(10-25)16(14)12-26-13-6-7-19(21)22-8-13/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	511	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263433 (1-methyl-2-(((1R,5S)-6-((5-(trifluoromethyl)pyridi...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cn4)C(F)(F)F)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C21H21F3N4O/c1-27-18-5-3-2-4-17(18)26-19(27)11-28-9-14-15(10-28)16(14)12-29-20-7-6-13(8-25-20)21(22,23)24/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263434 (1-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenox...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2ncccc12 |r| Show InChI InChI=1S/C21H21F3N4O/c1-27-18-3-2-8-25-20(18)26-19(27)11-28-9-15-16(10-28)17(15)12-29-14-6-4-13(5-7-14)21(22,23)24/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274140 (1-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenox...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2cnccc12 |r| Show InChI InChI=1S/C21H21F3N4O/c1-27-19-6-7-25-8-18(19)26-20(27)11-28-9-15-16(10-28)17(15)12-29-14-4-2-13(3-5-14)21(22,23)24/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274141 (3-methyl-2-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyc...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccccc4)[C@H]3C2)nc2ccncc12 |r| Show InChI InChI=1S/C20H22N4O/c1-23-19-9-21-8-7-18(19)22-20(23)12-24-10-15-16(11-24)17(15)13-25-14-5-3-2-4-6-14/h2-9,15-17H,10-13H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274142 (3-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenox...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2cccnc12 |r| Show InChI InChI=1S/C21H21F3N4O/c1-27-19(26-18-3-2-8-25-20(18)27)11-28-9-15-16(10-28)17(15)12-29-14-6-4-13(5-7-14)21(22,23)24/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	419	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274143 (2-(((1R,5S)-6-((3-chlorophenoxy)methyl)-3-aza-bicy...) Show SMILES Cn1c(CN2C[C@H]3C(COc4cccc(Cl)c4)[C@H]3C2)nc2ncccc12 |r| Show InChI InChI=1S/C20H21ClN4O/c1-24-18-6-3-7-22-20(18)23-19(24)11-25-9-15-16(10-25)17(15)12-26-14-5-2-4-13(21)8-14/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274144 (2-(((1R,5S)-6-((3-chlorophenoxy)methyl)-3-aza-bicy...) Show SMILES Cn1c(CN2C[C@H]3C(COc4cccc(Cl)c4)[C@H]3C2)nc2cnccc12 |r| Show InChI InChI=1S/C20H21ClN4O/c1-24-19-5-6-22-8-18(19)23-20(24)11-25-9-15-16(10-25)17(15)12-26-14-4-2-3-13(21)7-14/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263426 (1-methyl-2-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyc...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccccc4)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C21H23N3O/c1-23-20-10-6-5-9-19(20)22-21(23)13-24-11-16-17(12-24)18(16)14-25-15-7-3-2-4-8-15/h2-10,16-18H,11-14H2,1H3/t16-,17+,18?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263427 (2-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyclo[3.1.0]...) Show SMILES C(Oc1ccccc1)C1[C@@H]2CN(Cc3nc4ccccc4s3)C[C@H]12 |r| Show InChI InChI=1S/C20H20N2OS/c1-2-6-14(7-3-1)23-13-17-15-10-22(11-16(15)17)12-20-21-18-8-4-5-9-19(18)24-20/h1-9,15-17H,10-13H2/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263428 (2-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyclo[3.1.0]...) Show SMILES C(Oc1ccccc1)C1[C@@H]2CN(Cc3cn4ccccc4n3)C[C@H]12 |r| Show InChI InChI=1S/C20H21N3O/c1-2-6-16(7-3-1)24-14-19-17-12-22(13-18(17)19)10-15-11-23-9-5-4-8-20(23)21-15/h1-9,11,17-19H,10,12-14H2/t17-,18+,19?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263429 (3-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyclo[3.1.0]...) Show SMILES C(Oc1ccccc1)C1[C@@H]2CN(Cc3cnc4ccccc4c3)C[C@H]12 |r| Show InChI InChI=1S/C22H22N2O/c1-2-7-18(8-3-1)25-15-21-19-13-24(14-20(19)21)12-16-10-17-6-4-5-9-22(17)23-11-16/h1-11,19-21H,12-15H2/t19-,20+,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.75E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263430 (1-cyclopropyl-2-(((1R,5S)-6-(phenoxymethyl)-3-aza-...) Show SMILES C(Oc1ccccc1)C1[C@@H]2CN(Cc3nc4ccccc4n3C3CC3)C[C@H]12 |r| Show InChI InChI=1S/C23H25N3O/c1-2-6-17(7-3-1)27-15-20-18-12-25(13-19(18)20)14-23-24-21-8-4-5-9-22(21)26(23)16-10-11-16/h1-9,16,18-20H,10-15H2/t18-,19+,20?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263353 (1-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyclo[3.1.0]...) Show SMILES C(Oc1ccccc1)C1[C@@H]2CN(Cc3nc4cccc5CCCn3c45)C[C@H]12 |r| Show InChI InChI=1S/C23H25N3O/c1-2-8-17(9-3-1)27-15-20-18-12-25(13-19(18)20)14-22-24-21-10-4-6-16-7-5-11-26(22)23(16)21/h1-4,6,8-10,18-20H,5,7,11-15H2/t18-,19+,20?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	967	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263354 (2-[(1R,5S)-6-(Biphenyl-3-yloxymethyl)-3-aza-bicycl...) Show SMILES Cn1c(CN2C[C@H]3C(COc4cccc(c4)-c4ccccc4)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C27H27N3O/c1-29-26-13-6-5-12-25(26)28-27(29)17-30-15-22-23(16-30)24(22)18-31-21-11-7-10-20(14-21)19-8-3-2-4-9-19/h2-14,22-24H,15-18H2,1H3/t22-,23+,24?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263355 (2-(((1R,5S)-6-((2,5-difluorophenoxy)methyl)-3-aza-...) Show SMILES Cn1c(CN2C[C@H]3C(COc4cc(F)ccc4F)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C21H21F2N3O/c1-25-19-5-3-2-4-18(19)24-21(25)11-26-9-14-15(10-26)16(14)12-27-20-8-13(22)6-7-17(20)23/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263389 (2-(((1R,5S)-6-((4-isopropylphenoxy)methyl)-3-aza-b...) Show SMILES CC(C)c1ccc(OCC2[C@@H]3CN(Cc4nc5ccccc5n4C)C[C@H]23)cc1 |r| Show InChI InChI=1S/C24H29N3O/c1-16(2)17-8-10-18(11-9-17)28-15-21-19-12-27(13-20(19)21)14-24-25-22-6-4-5-7-23(22)26(24)3/h4-11,16,19-21H,12-15H2,1-3H3/t19-,20+,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263390 (2-(((1R,5S)-6-((4-chlorophenoxy)methyl)-3-aza-bicy...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(Cl)cc4)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C21H22ClN3O/c1-24-20-5-3-2-4-19(20)23-21(24)12-25-10-16-17(11-25)18(16)13-26-15-8-6-14(22)7-9-15/h2-9,16-18H,10-13H2,1H3/t16-,17+,18?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263391 (2-(((1R,5S)-6-((4-chloro-2-fluorophenoxy)methyl)-3...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(Cl)cc4F)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C21H21ClFN3O/c1-25-19-5-3-2-4-18(19)24-21(25)11-26-9-14-15(10-26)16(14)12-27-20-7-6-13(22)8-17(20)23/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263392 (1-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenox...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C22H22F3N3O/c1-27-20-5-3-2-4-19(20)26-21(27)12-28-10-16-17(11-28)18(16)13-29-15-8-6-14(7-9-15)22(23,24)25/h2-9,16-18H,10-13H2,1H3/t16-,17+,18?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50263431 (2-(((1R,5S)-6-((5-chloropyridin-2-yloxy)methyl)-3-...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(Cl)cn4)[C@H]3C2)nc2ccccc12 |r| Show InChI InChI=1S/C20H21ClN4O/c1-24-18-5-3-2-4-17(18)23-19(24)11-25-9-14-15(10-25)16(14)12-26-20-7-6-13(21)8-22-20/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50343295 (2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...) Show SMILES COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1 Show InChI InChI=1S/C21H25N3O/c1-23-19-9-5-4-8-18(19)22-21(23)15-24-13-11-16(12-14-24)17-7-3-6-10-20(17)25-2/h3-10,16H,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	951	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole-induced effect				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343296 (4-bromo-5-((4-(2-methoxyphenyl)piperazin-1-yl)meth...) Show SMILES COc1ccccc1N1CCN(Cc2c(Br)c(=O)n(-c3ccccc3)n2C)CC1 Show InChI InChI=1S/C22H25BrN4O2/c1-24-19(21(23)22(28)27(24)17-8-4-3-5-9-17)16-25-12-14-26(15-13-25)18-10-6-7-11-20(18)29-2/h3-11H,12-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	891	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343297 (1-methyl-2-((4-(6-methyl-2-(pyrrolidin-1-yl)pyrimi...) Show SMILES Cc1cc(nc(n1)N1CCCC1)C1CCN(Cc2nc3ccccc3n2C)CC1 Show InChI InChI=1S/C23H30N6/c1-17-15-20(26-23(24-17)29-11-5-6-12-29)18-9-13-28(14-10-18)16-22-25-19-7-3-4-8-21(19)27(22)2/h3-4,7-8,15,18H,5-6,9-14,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.79E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343295 (2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...) Show SMILES COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1 Show InChI InChI=1S/C21H25N3O/c1-23-19-9-5-4-8-18(19)22-21(23)15-24-13-11-16(12-14-24)17-7-3-6-10-20(17)25-2/h3-10,16H,11-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343298 (1-Methyl-2-((4-phenylpiperidin-1-yl)methyl)-1H-ben...) Show SMILES Cn1c(CN2CCC(CC2)c2ccccc2)nc2ccccc12 Show InChI InChI=1S/C20H23N3/c1-22-19-10-6-5-9-18(19)21-20(22)15-23-13-11-17(12-14-23)16-7-3-2-4-8-16/h2-10,17H,11-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	212	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343299 (2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2ccccc2F)nc2ccccc12 Show InChI InChI=1S/C20H22FN3/c1-23-19-9-5-4-8-18(19)22-20(23)14-24-12-10-15(11-13-24)16-6-2-3-7-17(16)21/h2-9,15H,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343300 (2-((4-(3-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2cccc(F)c2)nc2ccccc12 Show InChI InChI=1S/C20H22FN3/c1-23-19-8-3-2-7-18(19)22-20(23)14-24-11-9-15(10-12-24)16-5-4-6-17(21)13-16/h2-8,13,15H,9-12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343301 (2-((4-(4-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(F)cc2)nc2ccccc12 Show InChI InChI=1S/C20H22FN3/c1-23-19-5-3-2-4-18(19)22-20(23)14-24-12-10-16(11-13-24)15-6-8-17(21)9-7-15/h2-9,16H,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	159	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343302 (2-((4-(2-Chlorophenyl)piperidin-1-yl)methyl)-1-met...) Show SMILES Cn1c(CN2CCC(CC2)c2ccccc2Cl)nc2ccccc12 Show InChI InChI=1S/C20H22ClN3/c1-23-19-9-5-4-8-18(19)22-20(23)14-24-12-10-15(11-13-24)16-6-2-3-7-17(16)21/h2-9,15H,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	144	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair

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