Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230775![]() (US9340537, 29 | US9896444, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230777![]() (US9340537, 31 | US9896444, Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230795![]() (US9340537, 49 | US9896444, Example 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230799![]() (US9340537, 53 | US9896444, Example 53) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230809![]() (US9340537, 63 | US9896444, Example 63) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230775![]() (US9340537, 29 | US9896444, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213682![]() (US9278981, 274) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG US Patent | Assay Description For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230795![]() (US9340537, 49 | US9896444, Example 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230799![]() (US9340537, 53 | US9896444, Example 53) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230809![]() (US9340537, 63 | US9896444, Example 63) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213659![]() (US9278981, 251) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG US Patent | Assay Description For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213662![]() (US9278981, 254) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG US Patent | Assay Description For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213677![]() (US9278981, 269) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG US Patent | Assay Description For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230777![]() (US9340537, 31 | US9896444, Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230826![]() (US9340537, 80 | US9896444, Example 80) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213581![]() (US9278981, 173) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230826![]() (US9340537, 80 | US9896444, Example 80) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230768![]() (US9340537, 22 | US9896444, Example 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230777![]() (US9340537, 31 | US9896444, Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230814![]() (US9340537, 68 | US9896444, Example 68) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213603![]() (US9278981, 195) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213613![]() (US9278981, 205) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213655![]() (US9278981, 247) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213656![]() (US9278981, 248) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213667![]() (US9278981, 259) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213671![]() (US9278981, 263) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213673![]() (US9278981, 265) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213677![]() (US9278981, 269) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230768![]() (US9340537, 22 | US9896444, Example 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230777![]() (US9340537, 31 | US9896444, Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213496![]() (US9278981, 88) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213559![]() (US9278981, 151) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213578![]() (US9278981, 170) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213579![]() (US9278981, 171) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230814![]() (US9340537, 68 | US9896444, Example 68) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.130 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM477669![]() (N-(4-(chlorodifluoromethoxy)phenyl)-7-(1H-imidazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Terns, Inc. US Patent | Assay Description ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent... | US Patent US10889571 (2021) BindingDB Entry DOI: 10.7270/Q27S7RW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | US20240101536, Example 11![]() (N-(4-(chlorodifluoromethoxy)phenyl)-7-(1H-imidazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230834![]() (US9340537, 88 | US9896444, Example 88) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213596![]() (US9278981, 188) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230801![]() (US9340537, 55 | US9896444, Example 55) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230810![]() (US9340537, 64 | US9896444, Example 64) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230815![]() (US9340537, 69 | US9896444, Example 69) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230834![]() (US9340537, 88 | US9896444, Example 88) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230835![]() (US9340537, 89 | US9896444, Example 89) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
NOVATIS AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230801![]() (US9340537, 55 | US9896444, Example 55) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230810![]() (US9340537, 64 | US9896444, Example 64) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230815![]() (US9340537, 69 | US9896444, Example 69) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230815![]() (US9340537, 69 | US9896444, Example 69) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were... | J Med Chem 50: 4953-75 (2007) BindingDB Entry DOI: 10.7270/Q2B27XKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM213699![]() (US9278981, 291) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Novartis AG US Patent | Assay Description The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition... | US Patent US9278981 (2016) BindingDB Entry DOI: 10.7270/Q2DV1HRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human)) | BDBM230815![]() (US9340537, 69 | US9896444, Example 69) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NOVATIS AG US Patent | Assay Description The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the... | US Patent US9340537 (2016) BindingDB Entry DOI: 10.7270/Q2FB51T5 | |||||||||||
More data for this Ligand-Target Pair |
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