Compile Data Set for Download or QSAR

Found 66 hits of ic50 for UniProtKB: P38158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223121 ((Z)-N'-(5-chloro-1-(2-fluorobenzyl)-2-oxoindol...) Show SMILES Fc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H17ClFN3O5/c27-17-7-9-21-19(11-17)25(26(34)31(21)13-16-3-1-2-4-20(16)28)30-29-23(32)14-35-18-8-5-15-6-10-24(33)36-22(15)12-18/h1-12H,13-14H2,(H,29,32)/b30-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223124 ((Z)-N'-(5-bromo-1-(2-chlorobenzyl)-2-oxoindoli...) Show SMILES Clc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2cc(Br)ccc12 Show InChI InChI=1S/C26H17BrClN3O5/c27-17-7-9-21-19(11-17)25(26(34)31(21)13-16-3-1-2-4-20(16)28)30-29-23(32)14-35-18-8-5-15-6-10-24(33)36-22(15)12-18/h1-12H,13-14H2,(H,29,32)/b30-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223122 ((Z)-N'-(5-chloro-1-(3-fluorobenzyl)-2-oxoindol...) Show SMILES Fc1cccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Cl)ccc23)c1 Show InChI InChI=1S/C26H17ClFN3O5/c27-17-6-8-21-20(11-17)25(26(34)31(21)13-15-2-1-3-18(28)10-15)30-29-23(32)14-35-19-7-4-16-5-9-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223125 ((Z)-N'-(5-bromo-1-(4-bromobenzyl)-2-oxoindolin...) Show SMILES Brc1ccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Br)ccc23)cc1 Show InChI InChI=1S/C26H17Br2N3O5/c27-17-5-1-15(2-6-17)13-31-21-9-7-18(28)11-20(21)25(26(31)34)30-29-23(32)14-35-19-8-3-16-4-10-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223118 ((Z)-N'-(1-(4-bromobenzyl)-2-oxoindolin-3-ylide...) Show SMILES Brc1ccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3ccccc23)cc1 Show InChI InChI=1S/C26H18BrN3O5/c27-18-9-5-16(6-10-18)14-30-21-4-2-1-3-20(21)25(26(30)33)29-28-23(31)15-34-19-11-7-17-8-12-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.07E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223123 ((Z)-N'-(1-benzyl-5-bromo-2-oxoindolin-3-yliden...) Show SMILES Brc1ccc2N(Cc3ccccc3)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C26H18BrN3O5/c27-18-8-10-21-20(12-18)25(26(33)30(21)14-16-4-2-1-3-5-16)29-28-23(31)15-34-19-9-6-17-7-11-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.48E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM19992 (2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...) Show SMILES OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 Show InChI InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23850 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2cc5)ccc4O)cc3)c1 Show InChI InChI=1S/C28H24O3/c29-24-12-15-26-22-9-3-19(4-10-22)1-2-21-8-16-27(30)28(17-21)31-25-13-6-20(7-14-25)5-11-23(26)18-24/h3-4,6-10,12-18,29-30H,1-2,5,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23851 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1ccc-2c(CCc3ccc(Oc4cccc(CCc5ccc-2c(O)c5)c4)cc3)c1 Show InChI InChI=1S/C28H24O3/c29-23-11-15-26-22(18-23)10-6-19-7-12-24(13-8-19)31-25-3-1-2-20(16-25)4-5-21-9-14-27(26)28(30)17-21/h1-3,7-9,11-18,29-30H,4-6,10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225289 (1,1''-bis(2-Fluorobenzyl)-[3,3':3'...) Show SMILES Fc1ccccc1Cn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(Cc2ccccc2F)c2ccccc12 Show InChI InChI=1S/C38H27F2N3O/c39-32-16-6-1-11-25(32)21-42-23-30(27-13-3-9-19-35(27)42)38(29-15-5-8-18-34(29)41-37(38)44)31-24-43(36-20-10-4-14-28(31)36)22-26-12-2-7-17-33(26)40/h1-20,23-24H,21-22H2,(H,41,44)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5.98E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225288 (1,1''-bis(2-Chlorobenzyl)-[3,3':3'...) Show SMILES Clc1ccccc1Cn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(Cc2ccccc2Cl)c2ccccc12 Show InChI InChI=1S/C38H27Cl2N3O/c39-32-16-6-1-11-25(32)21-42-23-30(27-13-3-9-19-35(27)42)38(29-15-5-8-18-34(29)41-37(38)44)31-24-43(36-20-10-4-14-28(31)36)22-26-12-2-7-17-33(26)40/h1-20,23-24H,21-22H2,(H,41,44)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7.31E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223117 ((Z)-N'-(1-(2-chlorobenzyl)-2-oxoindolin-3-ylid...) Show SMILES Clc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2ccccc12 Show InChI InChI=1S/C26H18ClN3O5/c27-20-7-3-1-5-17(20)14-30-21-8-4-2-6-19(21)25(26(30)33)29-28-23(31)15-34-18-11-9-16-10-12-24(32)35-22(16)13-18/h1-13H,14-15H2,(H,28,31)/b29-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.31E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223115 ((Z)-N'-(1-(2-fluorobenzyl)-2-oxoindolin-3-ylid...) Show SMILES Fc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2ccccc12 Show InChI InChI=1S/C26H18FN3O5/c27-20-7-3-1-5-17(20)14-30-21-8-4-2-6-19(21)25(26(30)33)29-28-23(31)15-34-18-11-9-16-10-12-24(32)35-22(16)13-18/h1-13H,14-15H2,(H,28,31)/b29-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.37E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225286 (1,1''-bis(3-Fluorobenzyl)-1H,1''H-...) Show SMILES Fc1cccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3cccc(F)c3)c3ccccc23)c1 Show InChI InChI=1S/C38H27F2N3O/c39-27-11-7-9-25(19-27)21-42-23-32(29-13-1-5-17-35(29)42)38(31-15-3-4-16-34(31)41-37(38)44)33-24-43(36-18-6-2-14-30(33)36)22-26-10-8-12-28(40)20-26/h1-20,23-24H,21-22H2,(H,41,44)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7.92E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23842 (2-[2,6-bis(propan-2-yl)phenyl]-3-sulfanylidene-2,3...) Show SMILES CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccccc2C1=S Show InChI InChI=1S/C20H21NOS/c1-12(2)14-10-7-11-15(13(3)4)18(14)21-19(22)16-8-5-6-9-17(16)20(21)23/h5-13H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23849 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1ccc2CCc3ccc(c(O)c3)-c3ccccc3CCc3ccc(Oc1c2)cc3 Show InChI InChI=1S/C28H24O3/c29-26-16-11-21-6-5-20-10-15-25(27(30)17-20)24-4-2-1-3-22(24)12-7-19-8-13-23(14-9-19)31-28(26)18-21/h1-4,8-11,13-18,29-30H,5-7,12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225287 (1,1''-bis(4-Bromobenzyl)-1H,1''H-[...) Show SMILES Brc1ccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3ccc(Br)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C38H27Br2N3O/c39-27-17-13-25(14-18-27)21-42-23-32(29-7-1-5-11-35(29)42)38(31-9-3-4-10-34(31)41-37(38)44)33-24-43(36-12-6-2-8-30(33)36)22-26-15-19-28(40)20-16-26/h1-20,23-24H,21-22H2,(H,41,44)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	9.16E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223116 ((Z)-N'-(1-(3-fluorobenzyl)-2-oxoindolin-3-ylid...) Show SMILES Fc1cccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3ccccc23)c1 Show InChI InChI=1S/C26H18FN3O5/c27-18-5-3-4-16(12-18)14-30-21-7-2-1-6-20(21)25(26(30)33)29-28-23(31)15-34-19-10-8-17-9-11-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.33E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223112 ((Z)-N'-(5-nitro-2-oxoindolin-3-ylidene)-2-((2-...) Show SMILES [O-][N+](=O)c1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C19H12N4O7/c24-16(9-29-12-4-1-10-2-6-17(25)30-15(10)8-12)21-22-18-13-7-11(23(27)28)3-5-14(13)20-19(18)26/h1-8H,9H2,(H,21,24)(H,20,22,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.47E+3	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225285 (1,1''-Dibenzyl-1H,1''H-[3,3':3...) Show SMILES O=C1Nc2ccccc2C1(c1cn(Cc2ccccc2)c2ccccc12)c1cn(Cc2ccccc2)c2ccccc12 Show InChI InChI=1S/C38H29N3O/c42-37-38(31-19-9-10-20-34(31)39-37,32-25-40(23-27-13-3-1-4-14-27)35-21-11-7-17-29(32)35)33-26-41(24-28-15-5-2-6-16-28)36-22-12-8-18-30(33)36/h1-22,25-26H,23-24H2,(H,39,42)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	9.83E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23839 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2c(O)c5)ccc4O)cc3)c1 Show InChI InChI=1S/C28H24O4/c29-22-9-13-24-21(17-22)8-3-18-4-10-23(11-5-18)32-28-16-20(7-14-26(28)30)2-1-19-6-12-25(24)27(31)15-19/h4-7,9-17,29-31H,1-3,8H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225291 (1,1''-Diisopropyl-[3,3':3',3'&...) Show SMILES CC(C)n1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(C(C)C)c2ccccc12 Show InChI InChI=1S/C30H29N3O/c1-19(2)32-17-24(21-11-5-9-15-27(21)32)30(23-13-7-8-14-26(23)31-29(30)34)25-18-33(20(3)4)28-16-10-6-12-22(25)28/h5-20H,1-4H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225290 (1,1''-Dipropyl-[3,3':3',3''...) Show SMILES CCCn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CCC)c2ccccc12 Show InChI InChI=1S/C30H29N3O/c1-3-17-32-19-24(21-11-5-9-15-27(21)32)30(23-13-7-8-14-26(23)31-29(30)34)25-20-33(18-4-2)28-16-10-6-12-22(25)28/h5-16,19-20H,3-4,17-18H2,1-2H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223109 ((Z)-N'-(5-fluoro-2-oxoindolin-3-ylidene)-2-((2...) Show SMILES Fc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C19H12FN3O5/c20-11-3-5-14-13(7-11)18(19(26)21-14)23-22-16(24)9-27-12-4-1-10-2-6-17(25)28-15(10)8-12/h1-8H,9H2,(H,22,24)(H,21,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225292 (1,1''-Dibutyl-[3,3':3',3''...) Show SMILES CCCCn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CCCC)c2ccccc12 Show InChI InChI=1S/C32H33N3O/c1-3-5-19-34-21-26(23-13-7-11-17-29(23)34)32(25-15-9-10-16-28(25)33-31(32)36)27-22-35(20-6-4-2)30-18-12-8-14-24(27)30/h7-18,21-22H,3-6,19-20H2,1-2H3,(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225284 (1,1''-Dimethyl-1H,1''H-[3,3':3...) Show SMILES Cn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(C)c2ccccc12 Show InChI InChI=1S/C26H21N3O/c1-28-15-20(17-9-3-7-13-23(17)28)26(19-11-5-6-12-22(19)27-25(26)30)21-16-29(2)24-14-8-4-10-18(21)24/h3-16H,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223114 ((Z)-N'-(1-benzyl-2-oxoindolin-3-ylidene)-2-((2...) Show SMILES O=C(COc1ccc2ccc(=O)oc2c1)N\N=C1/C(=O)N(Cc2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H19N3O5/c30-23(16-33-19-12-10-18-11-13-24(31)34-22(18)14-19)27-28-25-20-8-4-5-9-21(20)29(26(25)32)15-17-6-2-1-3-7-17/h1-14H,15-16H2,(H,27,30)/b28-25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223111 ((Z)-N'-(5-bromo-2-oxoindolin-3-ylidene)-2-((2-...) Show SMILES Brc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C19H12BrN3O5/c20-11-3-5-14-13(7-11)18(19(26)21-14)23-22-16(24)9-27-12-4-1-10-2-6-17(25)28-15(10)8-12/h1-8H,9H2,(H,22,24)(H,21,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225293 (1,1''-Diisobutyl-[3,3':3',3'&#...) Show SMILES CC(C)Cn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CC(C)C)c2ccccc12 Show InChI InChI=1S/C32H33N3O/c1-21(2)17-34-19-26(23-11-5-9-15-29(23)34)32(25-13-7-8-14-28(25)33-31(32)36)27-20-35(18-22(3)4)30-16-10-6-12-24(27)30/h5-16,19-22H,17-18H2,1-4H3,(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23852 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1ccc2CCc3ccc(cc3)-c3ccccc3CCc3ccc(Oc1c2)cc3 Show InChI InChI=1S/C28H24O2/c29-27-18-12-22-6-5-20-8-14-24(15-9-20)26-4-2-1-3-23(26)13-7-21-10-16-25(17-11-21)30-28(27)19-22/h1-4,8-12,14-19,29H,5-7,13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23840 (2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...) Show SMILES O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 Show InChI InChI=1S/C22H17NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23854 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES C1Cc2cccc(Oc3ccc(CCc4ccccc4-c4ccc1cc4)cc3)c2 Show InChI InChI=1S/C28H24O/c1-2-7-28-24(5-1)15-10-22-13-18-26(19-14-22)29-27-6-3-4-23(20-27)9-8-21-11-16-25(28)17-12-21/h1-7,11-14,16-20H,8-10,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23853 (14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...) Show SMILES Oc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 Show InChI InChI=1S/C28H24O2/c29-28-19-22-9-8-21-4-3-6-25(18-21)30-24-15-11-20(12-16-24)10-14-23-5-1-2-7-26(23)27(28)17-13-22/h1-7,11-13,15-19,29H,8-10,14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225282 (5'-Bromo-1H,1''H-[3,3':3',3...) Show SMILES Brc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16BrN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23841 (2-(2-hexylphenyl)-2,3-dihydro-1H-isoindole-1,3-dio...) Show SMILES CCCCCCc1ccccc1N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C20H21NO2/c1-2-3-4-5-10-15-11-6-9-14-18(15)21-19(22)16-12-7-8-13-17(16)20(21)23/h6-9,11-14H,2-5,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23846 (5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...) Show SMILES COc1ccc-2c(CCc3ccc(Oc4cccc(CCc5ccc-2c(OC)c5)c4)cc3)c1 Show InChI InChI=1S/C30H28O3/c1-31-26-15-17-28-24(20-26)12-8-21-9-13-25(14-10-21)33-27-5-3-4-22(18-27)6-7-23-11-16-29(28)30(19-23)32-2/h3-5,9-11,13-20H,6-8,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225283 (5'-Methyl-1H,1''H-[3,3':3',3&#...) Show SMILES Cc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C25H19N3O/c1-15-10-11-23-18(12-15)25(24(29)28-23,19-13-26-21-8-4-2-6-16(19)21)20-14-27-22-9-5-3-7-17(20)22/h2-14,26-27H,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23845 (5,16-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...) Show SMILES COc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2cc5)ccc4OC)cc3)c1 Show InChI InChI=1S/C30H28O3/c1-31-27-16-17-28-24-11-5-21(6-12-24)3-4-23-10-18-29(32-2)30(19-23)33-26-14-8-22(9-15-26)7-13-25(28)20-27/h5-6,8-12,14-20H,3-4,7,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23844 (16,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}....) Show SMILES COc1ccc2CCc3ccc(c(OC)c3)-c3ccccc3CCc3ccc(Oc1c2)cc3 Show InChI InChI=1S/C30H28O3/c1-31-28-18-13-23-8-7-22-12-17-27(29(19-22)32-2)26-6-4-3-5-24(26)14-9-21-10-15-25(16-11-21)33-30(28)20-23/h3-6,10-13,15-20H,7-9,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23843 (5,16,25-trimethoxy-14-oxapentacyclo[20.2.2.2^{10,1...) Show SMILES COc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2c(OC)c5)ccc4OC)cc3)c1 Show InChI InChI=1S/C31H30O4/c1-32-26-14-16-27-24(20-26)11-6-21-7-12-25(13-8-21)35-31-19-23(10-17-29(31)33-2)5-4-22-9-15-28(27)30(18-22)34-3/h7-10,12-20H,4-6,11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM50068234 (5'-Chloro-1H,1''H-[3,3':3',3&#...) Show SMILES Clc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H16ClN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223119 ((Z)-N'-(1-(2-fluorobenzyl)-5-methyl-2-oxoindol...) Show SMILES Cc1ccc2N(Cc3ccccc3F)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C27H20FN3O5/c1-16-6-10-22-20(12-16)26(27(34)31(22)14-18-4-2-3-5-21(18)28)30-29-24(32)15-35-19-9-7-17-8-11-25(33)36-23(17)13-19/h2-13H,14-15H2,1H3,(H,29,32)/b30-26-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.68E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23848 (25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...) Show SMILES COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 Show InChI InChI=1S/C29H26O2/c1-30-29-20-23-10-9-22-5-4-7-26(19-22)31-25-16-12-21(13-17-25)11-15-24-6-2-3-8-27(24)28(29)18-14-23/h2-8,12-14,16-20H,9-11,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223120 ((Z)-N'-(1-(3-fluorobenzyl)-5-methyl-2-oxoindol...) Show SMILES Cc1ccc2N(Cc3cccc(F)c3)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C27H20FN3O5/c1-16-5-9-22-21(11-16)26(27(34)31(22)14-17-3-2-4-19(28)12-17)30-29-24(32)15-35-20-8-6-18-7-10-25(33)36-23(18)13-20/h2-13H,14-15H2,1H3,(H,29,32)/b30-26-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.78E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23838 ((2R,5S,14S,16R)-14-[(2S,3R)-3-hydroxy-6-methylhept...) Show SMILES [H][C@@]1(CCC2C1[C@H](C)CC1C2CC=C2C[C@@H](O)CC[C@]12C)[C@H](C)[C@H](O)CCC(C)C |r,t:14| Show InChI InChI=1S/C27H46O2/c1-16(2)6-11-25(29)18(4)21-9-10-23-22-8-7-19-15-20(28)12-13-27(19,5)24(22)14-17(3)26(21)23/h7,16-18,20-26,28-29H,6,8-15H2,1-5H3/t17-,18+,20+,21-,22?,23?,24?,25-,26?,27+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) Show SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM23847 (16-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...) Show SMILES COc1ccc2CCc3ccc(cc3)-c3ccccc3CCc3ccc(Oc1c2)cc3 Show InChI InChI=1S/C29H26O2/c1-30-28-19-13-23-7-6-21-9-15-25(16-10-21)27-5-3-2-4-24(27)14-8-22-11-17-26(18-12-22)31-29(28)20-23/h2-5,9-13,15-20H,6-8,14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM19459 (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.0	37
University of Tokyo					Assay Description The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...				Bioorg Med Chem 16: 4272-85 (2008) Article DOI: 10.1016/j.bmc.2008.02.078 BindingDB Entry DOI: 10.7270/Q28S4N7J
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM223107 ((Z)-N'-(5-methyl-2-oxoindolin-3-ylidene)-2-((2...) Show SMILES Cc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1 Show InChI InChI=1S/C20H15N3O5/c1-11-2-6-15-14(8-11)19(20(26)21-15)23-22-17(24)10-27-13-5-3-12-4-7-18(25)28-16(12)9-13/h2-9H,10H2,1H3,(H,22,24)(H,21,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...				Chem Biol Drug Des 89: 456-463 (2017) Article DOI: 10.1111/cbdd.12867 BindingDB Entry DOI: 10.7270/Q25M64KX
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM222412 (3-[1-(3,4, 5-trimethoxyphenyl)-1H-[1,2,3]triazol-4...) Show SMILES COc1cc(cc(OC)c1OC)-n1cc(CCC(=O)N[C@@H]2OC(CO)[C@@H](O)C(O)C2O)nn1 |r| Show InChI InChI=1S/C20H28N4O9/c1-30-12-6-11(7-13(31-2)19(12)32-3)24-8-10(22-23-24)4-5-15(26)21-20-18(29)17(28)16(27)14(9-25)33-20/h6-8,14,16-18,20,25,27-29H,4-5,9H2,1-3H3,(H,21,26)/t14?,16-,17?,18?,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	6.8	1
CSIR-Indian Institute of Chemical Biology					Assay Description Briefly, the sample solution (25 μL, 1.0 mM solution in DMSO) was mixed with enzyme solution (25 μL, 0.5 U/mL prepared in 0.1 M phosphate buffe...				Bioorg Chem 72: 11-20 (2017) Article DOI: 10.1016/j.bioorg.2017.03.006 BindingDB Entry DOI: 10.7270/Q2D7999X
					More data for this Ligand-Target Pair

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