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Compile Data Set for Download or QSAR

Found 145 hits Enz. Inhib. hit(s) with all data for entry = 50007395   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50067678
PNG
((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Show SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 |r,t:28|
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
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0.340n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062415
PNG
(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21ClFNO/c1-14-13-25(2,3)28-20-11-9-17-16-6-4-5-7-21(16)29-24(23(17)22(14)20)15-8-10-18(26)19(27)12-15/h4-13,24,28H,1-3H3
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0.410n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062406
PNG
(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22ClNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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0.430n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062409
PNG
(5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)cc4)c3c12 |t:1|
Show InChI InChI=1S/C25H22BrNO/c1-15-14-25(2,3)27-20-13-12-19-18-6-4-5-7-21(18)28-24(23(19)22(15)20)16-8-10-17(26)11-9-16/h4-14,24,27H,1-3H3
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0.550n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062419
PNG
(5-(3-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22FNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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0.690n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062417
PNG
(5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)cc4)c3c12 |t:1|
Show InChI InChI=1S/C25H22ClNO/c1-15-14-25(2,3)27-20-13-12-19-18-6-4-5-7-21(18)28-24(23(19)22(15)20)16-8-10-17(26)11-9-16/h4-14,24,27H,1-3H3
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0.700n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062413
PNG
(5-(3-Bromo-5-methyl-phenyl)-2,2,4-trimethyl-2,5-di...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(C)cc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24BrNO/c1-15-11-17(13-18(27)12-15)25-24-20(19-7-5-6-8-22(19)29-25)9-10-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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0.870n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062407
PNG
(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22BrNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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1.10n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062414
PNG
(5-(4-Chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(C)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24ClNO/c1-15-13-17(9-11-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)10-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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1.20n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062421
PNG
(5-(3,5-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(Cl)cc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21Cl2NO/c1-14-13-25(2,3)28-20-9-8-19-18-6-4-5-7-21(18)29-24(23(19)22(14)20)15-10-16(26)12-17(27)11-15/h4-13,24,28H,1-3H3
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1.70n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062416
PNG
(5-(3-Fluoro-4-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24FNO/c1-15-9-10-17(13-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)11-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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1.80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062411
PNG
(2,2,4-Trimethyl-5-p-tolyl-2,5-dihydro-1H-6-oxa-1-a...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)cc4)c3c12 |t:1|
Show InChI InChI=1S/C26H25NO/c1-16-9-11-18(12-10-16)25-24-20(19-7-5-6-8-22(19)28-25)13-14-21-23(24)17(2)15-26(3,4)27-21/h5-15,25,27H,1-4H3
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2.30n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062422
PNG
(5-(3-Bromo-5-fluoro-phenyl)-2,2,4-trimethyl-2,5-di...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(F)cc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21BrFNO/c1-14-13-25(2,3)28-20-9-8-19-18-6-4-5-7-21(18)29-24(23(19)22(14)20)15-10-16(26)12-17(27)11-15/h4-13,24,28H,1-3H3
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2.40n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062405
PNG
(2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(c4)C(F)(F)F)c3c12 |t:1|
Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-12-11-19-18-9-4-5-10-21(18)31-24(23(19)22(15)20)16-7-6-8-17(13-16)26(27,28)29/h4-14,24,30H,1-3H3
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2.60n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50067678
PNG
((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Show SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 |r,t:28|
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
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2.90n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062423
PNG
(5-(3,4-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21Cl2NO/c1-14-13-25(2,3)28-20-11-9-17-16-6-4-5-7-21(16)29-24(23(17)22(14)20)15-8-10-18(26)19(27)12-15/h4-13,24,28H,1-3H3
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3.40n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM8903
PNG
((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:20|
Show InChI InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
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3.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062410
PNG
(2,2,4-Trimethyl-5-phenyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccccc4)c3c12 |t:1|
Show InChI InChI=1S/C25H23NO/c1-16-15-25(2,3)26-20-14-13-19-18-11-7-8-12-21(18)27-24(23(19)22(16)20)17-9-5-4-6-10-17/h4-15,24,26H,1-3H3
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3.60n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062418
PNG
(5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)nc4)c3c12 |t:1|
Show InChI InChI=1S/C24H21BrN2O/c1-14-12-24(2,3)27-18-10-9-17-16-6-4-5-7-19(16)28-23(22(17)21(14)18)15-8-11-20(25)26-13-15/h4-13,23,27H,1-3H3
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3.90n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062403
PNG
(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(F)cc4)c3c12 |t:1|
Show InChI InChI=1S/C25H22FNO/c1-15-14-25(2,3)27-20-13-12-19-18-6-4-5-7-21(18)28-24(23(19)22(15)20)16-8-10-17(26)11-9-16/h4-14,24,27H,1-3H3
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5.30n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062425
PNG
(5-(4-Fluoro-3-trifluoromethyl-phenyl)-2,2,4-trimet...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(F)c(c4)C(F)(F)F)c3c12 |t:1|
Show InChI InChI=1S/C26H21F4NO/c1-14-13-25(2,3)31-20-11-9-17-16-6-4-5-7-21(16)32-24(23(17)22(14)20)15-8-10-19(27)18(12-15)26(28,29)30/h4-13,24,31H,1-3H3
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6.80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM8903
PNG
((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:20|
Show InChI InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
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8.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062424
PNG
(1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...)
Show SMILES CC(=O)c1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:27|
Show InChI InChI=1S/C27H25NO2/c1-16-15-27(3,4)28-22-14-13-21-20-7-5-6-8-23(20)30-26(25(21)24(16)22)19-11-9-18(10-12-19)17(2)29/h5-15,26,28H,1-4H3
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8.80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062408
PNG
(2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(cc4)C(F)(F)F)c3c12 |t:1|
Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-13-12-19-18-6-4-5-7-21(18)31-24(23(19)22(15)20)16-8-10-17(11-9-16)26(27,28)29/h4-14,24,30H,1-3H3
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11n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062412
PNG
(5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1...)
Show SMILES COc1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:26|
Show InChI InChI=1S/C26H25NO2/c1-16-15-26(2,3)27-21-14-13-20-19-7-5-6-8-22(19)29-25(24(20)23(16)21)17-9-11-18(28-4)12-10-17/h5-15,25,27H,1-4H3
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13n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50067678
PNG
((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Show SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 |r,t:28|
Show InChI InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
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13n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50062420
PNG
(5-(6-Bromo-pyridin-2-yl)-2,2,4-trimethyl-2,5-dihyd...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Br)n4)c3c12 |t:1|
Show InChI InChI=1S/C24H21BrN2O/c1-14-13-24(2,3)27-17-12-11-16-15-7-4-5-9-19(15)28-23(22(16)21(14)17)18-8-6-10-20(25)26-18/h4-13,23,27H,1-3H3
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13.8n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM8903
PNG
((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:20|
Show InChI InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
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31n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062407
PNG
(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22BrNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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34n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062415
PNG
(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21ClFNO/c1-14-13-25(2,3)28-20-11-9-17-16-6-4-5-7-21(16)29-24(23(17)22(14)20)15-8-10-18(26)19(27)12-15/h4-13,24,28H,1-3H3
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39n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062413
PNG
(5-(3-Bromo-5-methyl-phenyl)-2,2,4-trimethyl-2,5-di...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(C)cc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24BrNO/c1-15-11-17(13-18(27)12-15)25-24-20(19-7-5-6-8-22(19)29-25)9-10-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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42n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062405
PNG
(2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(c4)C(F)(F)F)c3c12 |t:1|
Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-12-11-19-18-9-4-5-10-21(18)31-24(23(19)22(15)20)16-7-6-8-17(13-16)26(27,28)29/h4-14,24,30H,1-3H3
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44n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062406
PNG
(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22ClNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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58n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062423
PNG
(5-(3,4-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21Cl2NO/c1-14-13-25(2,3)28-20-11-9-17-16-6-4-5-7-21(16)29-24(23(17)22(14)20)15-8-10-18(26)19(27)12-15/h4-13,24,28H,1-3H3
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59n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062416
PNG
(5-(3-Fluoro-4-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24FNO/c1-15-9-10-17(13-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)11-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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60n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062409
PNG
(5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)cc4)c3c12 |t:1|
Show InChI InChI=1S/C25H22BrNO/c1-15-14-25(2,3)27-20-13-12-19-18-6-4-5-7-21(18)28-24(23(19)22(15)20)16-8-10-17(26)11-9-16/h4-14,24,27H,1-3H3
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67n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062411
PNG
(2,2,4-Trimethyl-5-p-tolyl-2,5-dihydro-1H-6-oxa-1-a...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)cc4)c3c12 |t:1|
Show InChI InChI=1S/C26H25NO/c1-16-9-11-18(12-10-16)25-24-20(19-7-5-6-8-22(19)28-25)13-14-21-23(24)17(2)15-26(3,4)27-21/h5-15,25,27H,1-4H3
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80n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062421
PNG
(5-(3,5-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(Cl)cc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21Cl2NO/c1-14-13-25(2,3)28-20-9-8-19-18-6-4-5-7-21(18)29-24(23(19)22(14)20)15-10-16(26)12-17(27)11-15/h4-13,24,28H,1-3H3
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100n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062414
PNG
(5-(4-Chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(C)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24ClNO/c1-15-13-17(9-11-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)10-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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147n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062417
PNG
(5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)cc4)c3c12 |t:1|
Show InChI InChI=1S/C25H22ClNO/c1-15-14-25(2,3)27-20-13-12-19-18-6-4-5-7-21(18)28-24(23(19)22(15)20)16-8-10-17(26)11-9-16/h4-14,24,27H,1-3H3
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152n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50062410
PNG
(2,2,4-Trimethyl-5-phenyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccccc4)c3c12 |t:1|
Show InChI InChI=1S/C25H23NO/c1-16-15-25(2,3)26-20-14-13-19-18-11-7-8-12-21(18)27-24(23(19)22(16)20)17-9-5-4-6-10-17/h4-15,24,26H,1-3H3
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154n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062405
PNG
(2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(c4)C(F)(F)F)c3c12 |t:1|
Show InChI InChI=1S/C26H22F3NO/c1-15-14-25(2,3)30-20-12-11-19-18-9-4-5-10-21(18)31-24(23(19)22(15)20)16-7-6-8-17(13-16)26(27,28)29/h4-14,24,30H,1-3H3
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795n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062415
PNG
(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21ClFNO/c1-14-13-25(2,3)28-20-11-9-17-16-6-4-5-7-21(16)29-24(23(17)22(14)20)15-8-10-18(26)19(27)12-15/h4-13,24,28H,1-3H3
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1.46E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062406
PNG
(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22ClNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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1.53E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062416
PNG
(5-(3-Fluoro-4-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)c(F)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24FNO/c1-15-9-10-17(13-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)11-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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1.58E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062410
PNG
(2,2,4-Trimethyl-5-phenyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccccc4)c3c12 |t:1|
Show InChI InChI=1S/C25H23NO/c1-16-15-25(2,3)26-20-14-13-19-18-11-7-8-12-21(18)27-24(23(19)22(16)20)17-9-5-4-6-10-17/h4-15,24,26H,1-3H3
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1.86E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062414
PNG
(5-(4-Chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Cl)c(C)c4)c3c12 |t:1|
Show InChI InChI=1S/C26H24ClNO/c1-15-13-17(9-11-20(15)27)25-24-19(18-7-5-6-8-22(18)29-25)10-12-21-23(24)16(2)14-26(3,4)28-21/h5-14,25,28H,1-4H3
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1.86E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062407
PNG
(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cccc(Br)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H22BrNO/c1-15-14-25(2,3)27-20-12-11-19-18-9-4-5-10-21(18)28-24(23(19)22(15)20)16-7-6-8-17(26)13-16/h4-14,24,27H,1-3H3
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2.14E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062411
PNG
(2,2,4-Trimethyl-5-p-tolyl-2,5-dihydro-1H-6-oxa-1-a...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(C)cc4)c3c12 |t:1|
Show InChI InChI=1S/C26H25NO/c1-16-9-11-18(12-10-16)25-24-20(19-7-5-6-8-22(19)28-25)13-14-21-23(24)17(2)15-26(3,4)27-21/h5-15,25,27H,1-4H3
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2.33E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50062421
PNG
(5-(3,5-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4cc(Cl)cc(Cl)c4)c3c12 |t:1|
Show InChI InChI=1S/C25H21Cl2NO/c1-14-13-25(2,3)28-20-9-8-19-18-6-4-5-7-21(18)29-24(23(19)22(14)20)15-10-16(26)12-17(27)11-15/h4-13,24,28H,1-3H3
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2.58E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.


J Med Chem 41: 291-302 (1998)


Article DOI: 10.1021/jm9705768
BindingDB Entry DOI: 10.7270/Q29W0DMD
More data for this
Ligand-Target Pair
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